检索结果-南通市图书馆

Early expressions of hypoxia-inducible factor 1alpha and vascular endothelial growth factor increase the neuronal plasticity of activated endogenous neural stem cells after focal cerebral ischemia

引用

Neural Regeneration Research 2014年第9期9卷 912-918页

作者： Seung Song jong-tae park Joo Young Na Man-Seok park Jeong-Kil Lee Min-Cheol Lee Hyung-Seok Kim Department of Forensic Medicine Chonnam National University Medical School Department of Neurology Chonnam National University Medical School Department of Neurosurgery Chonnam National University Medical School Department of Pathology Chonnam National University Medical School

Endogenous neural stem cells become ＂activated＂ after neuronal injury, but the activation sequence and fate of endogenous neural stem cells in focal cerebral ischemia model are little known. We evaluated the relationships between neural stem cells and hypoxia-inducible factor-1α and vascular endothelial growth factor expression in a photothromobotic rat stroke model using immunohistochemistry and western blot analysis. We also evaluated the chronological changes of neural stem cells by 5-bromo-2′-deoxyuridine（BrdU） incorporation. Hypoxia-inducible factor-1α expression was initially increased from 1 hour after ischemic injury, followed by vascular endothelial growth factor expression. Hypoxia-inducible factor-1α immunoreactivity was detected in the ipsilateral cortical neurons of the infarct core and peri-infarct area. Vascular endothelial growth factor immunoreactivity was detected in bilateral cortex, but ipsilateral cortex staining intensity and numbers were greater than the contralateral cortex. Vascular endothelial growth factor immunoreactive cells were easily found along the peri-infarct area 12 hours after focal cerebral ischemia. The expression of nestin increased throughout the microvasculature in the ischemic core and the peri-infarct area in all experimental rats after 24 hours of ischemic injury. Nestin immunoreactivity increased in the subventricular zone during 12 hours to 3 days, and prominently increased in the ipsilateral cortex between 3–7 days. Nestin-labeled cells showed dual differentiation with microvessels near the infarct core and reactive astrocytes in the peri-infarct area. BrdU-labeled cells were increased gradually from day 1 in the ipsilateral subventricular zone and cortex, and numerous BrdU-labeled cells were observed in the peri-infarct area and non-lesioned cortex at 3 days. BrdU-labeled cells rather than neurons, were mainly co-labeled with nestin and GFAP. Early expressions of hypoxia-inducible factor-1α and vascular endothelial gr

关键词： nerve regeneration brain ischemia neural stem cell neural precursor cell hypoxia-inducible factor 1α vascular endothelial growth factor microenvironment photothrombosis neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Energy-Efficieng MAC Protocols for Wireless Body Area Networks: A Survey

引用

China Communications 2011年第5期8卷 1-10页

作者： Sai Anand Gopalan jong-tae park School of Electronics Engineering Kyungpook National University

In this paper, we provide a comprehensive survey of key energy-efficient Medium Access Control (MAC) protocols for Wireless Body Area Networks (WBANs). At the outset, we outline the crucial attributes of a good MAC protocol for WBAN. Several sources that contribute to the energy inefficiency of WBAN are identified, and features of the various MAC protocols qualitatively compared. Then, we further investigate some representative TDMA-based energy-efficient MAC protocols for WBAN by emphasizing their strengths and weaknesses. Finally, we conclude with a number of open research issues with regard to WBAN MAC layer.

关键词： Medium Access Control (MAC) Wireless Body Area Networks (WBANs) energy-efficiency

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Thermal energy harvesting circuit with maximum power point tracking control for self-powered sensor node applications

引用

Frontiers of Information Technology & Electronic Engineering 2018年第2期19卷 285-296页

作者： Eun-Jung YOON jong-tae park Chong-Gun YU Department of Electronics Engineering Incheon National University

We present a simple implementation of a thermal energy harvesting circuit with the maximum power point tracking（MPPT） control for self-powered miniature-sized sensor nodes. Complex start-up circuitry and direct current to direct current（DC-DC） boost converters are not required, because the output voltage of targeted thermoelectric generator（TEG） devices is high enough to drive the load applications directly. The circuit operates in the active/asleep mode to overcome the power mismatch between TEG devices and load applications. The proposed circuit was implemented using a 0.35-μm complementary metal-oxide semiconductor（CMOS） process. Experimental results confirmed correct circuit operation and demonstrated the performance of the MPPT scheme. The circuit achieved a peak power efficiency of 95.5% and an MPPT accuracy of higher than 99%.

关键词： Thermoelectric energy Energy harvesting Maximum power point tracking (MPPT) control Self-powered system Sensor node

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of electrical stimulation on neural regeneration via the p38-RhoA and ERK1/2-Bcl-2 pathways in spinal cord-injured rats

引用

Neural Regeneration Research 2018年第2期13卷 340-346页

作者： Min Cheol Joo Chul Hwan Jang jong tae park Seung Won Choi Seungil Ro Min Seob Kim Moon Young Lee Department of Rehabilitation Medicine and Institute of Wonkwang Medical Science School of Medicine Wonkwang University Department of Neurosurgery School of Medicine Wonkwang University Department of Anesthesiology and Pain Medicine School of Medicine Wonkwang University Department of Physiology and Cell Biology School of Medicine University of Nevada Department of Physiology and Institute of Wonkwang Medical Science School of Medicine Wonkwang University

Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury （SCI）. To identify the signaling pathway involved in electrical stimulation improving the function of injured spinal cord, 21 female Sprague-Dawley rats were randomly assigned to three groups： control （no surgical intervention, n = 6）, SCI （SCI only, n = 5）, and electrical simulation （ES; SCI induction followed by ES treatment, n = 10）. A complete spinal cord transection was performed at the 10^th thoracic level. Electrical stimulation of the injured spinal cord region was applied for 4 hours per day for 7 days. On days 2 and 7 post SCI, the Touch-Test Sensory Evaluators and the Basso-Beattie-Bresnahan locomotor scale were used to evaluate rat sensory and motor function. Somatosensory-evoked potentials of the tibial nerve of a hind paw of the rat were measured to evaluate the electrophysiological function of injured spinal cord. Western blot analysis was performed to measure p38-RhoA and ERK1/2-Bcl-2 pathways related protein levels in the injured spinal cord. Rat sensory and motor functions were similar between SCI and ES groups. Com- pared with the SCI group, in the ES group, the latencies of the somatosensory-evoked potential of the tibial nerve of rats were significantly shortened, the amplitudes were significantly increased, RhoA protein level was significantly decreased, protein gene product 9.5 expression, ERK1/2, p38, and Bcl-2 protein levels in the spinal cord were significantly increased. These data suggest that ES can promote the recovery of electrophysiological function of the injured spinal cord through regulating p38-RhoA and ERK1/2-Bcl-2 pathway-related protein levels in the injured spinal cord.

关键词： Bcl-2 ERKI/2 p38 PGP9.5 RhoA spinal cord injury somatosensory evoked potential muscle contraction electrical impulses neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Wearable Triboelectric Nanogenerators Based on Printed Polyvinylidene Fluoride Films Incorporated with Cobalt-Based Metal-Organic Framework for Self-Powered Mobile Electronics

引用

Energy & Environmental Materials 2024年第4期7卷 396-403页

作者： Myeong-Hyeon Kim Sang-Joon park tae-Jun Ha Department of Electronic Materials Engineering Kwangwoon University

In this study,wearable triboelectric nanogenerators comprising bar-printed polyvinylidene fluoride (PVDF) films incorporated with cobalt-based metalorganic framework (Co-MOF) were *** enhanced output performance of the TENCs was attributed to the phase transition of PVDF from α-crystals to β-crystals,as facilitated by the incorporation of the MOF.

关键词： bar printing phase transition polyvinylidene fluoride incorporated with cobalt-based metal–organic framework self-powered mobile electronics wearable triboelectric nanogenerators

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Tailoring local structures of atomically dispersed copper sites for highly selective CO_(2) electroreduction

引用

Carbon Energy 2024年第4期6卷 79-90页

作者： Kyung‐jong Noh Byoung Joon park Ying Wang Yejung Choi Sang‐Hoon You Yong‐tae Kim Kug‐Seung Lee Jeong Woo Han Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)PohangGyeongbukRepublic of Korea Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)PohangGyeongbukRepublic of Korea Pohang Accelerator Laboratory(PAL) Beamline DivisionPohangGyeongbukRepublic of Korea

Atomically‐dispersed copper sites coordinated with nitrogen‐doped carbon(Cu–N–C)can provide novel possibilities to enable highly selective and active electrochemical CO_(2) reduction ***,the construction of optimal local electronic structures for nitrogen‐coordinated Cu sites(Cu–N_(4))on carbon remains ***,we synthesized the Cu–N–C catalysts with atomically‐dispersed edge‐hosted Cu–N_(4) sites(Cu–N_(4)C_(8))located in a micropore between two graphitic sheets via a facile method to control the concentration of metal ***‐hosted Cu–N_(4)C_(8) catalysts outperformed the previously reported M–N–C catalysts for CO_(2)‐to‐CO conversion,achieving a maximum CO Faradaic efficiency(FECO)of 96%,a CO current density of–8.97 mA cm^(–2) at–0.8 V versus reversible hydrogen electrode(RHE),and over FECO of 90%from–0.6 to–1.0 V versus *** studies revealed that the micropore of the graphitic layer in edge‐hosted Cu–N_(4)C_(8) sites causes the d‐orbital energy level of the Cu atom to shift upward,which in return decreases the occupancy of antibonding states in the*COOH *** research suggests new insights into tailoring the locally coordinated structure of the electrocatalyst at the atomic scale to achieve highly selective electrocatalytic reactions.

关键词： atomic local structure density functional theory electrochemical CO_(2)reduction metal nitrogen‐doped carbon single‐atom catalyst

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Upcycling plastic wastes into value-added products via electrocatalysis and photoelectrocatalysis

引用

Journal of Energy Chemistry 2024年第4期91卷 522-541页

作者： Sungsoon Kim Dongjae Kong Xiaolin Zheng jong Hyeok park Department of Chemical&Biomolecular Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Mechanical Engineering Stanford UniversityStanfordCA 94305USA

Plastic,renowned for its versatility,durability,and cost-effectiveness,is indispensable in modern ***,the annual production of nearly 400 million tons of plastic,coupled with a recycling rate of only 9%,has led to a monumental environmental *** recycling has emerged as a vital response to this crisis,offering sustainable solutions to mitigate its environmental *** these recycling efforts,plastic upcycling has garnered attention,which elevates discarded plastics into higher-value ***,electrocatalytic and photoelectrocatalytic treatments stand at the forefront of advanced plastic *** or photoelectrocatalytic treatments involve chemical reactions that facilitate electron transfer through the electrode/electrolyte interface,driven by electrical or solar energy,*** methods enable precise control of chemical reactions,harnessing potential,current density,or light to yield valuable chemical *** review explores recent progress in plastic upcycling through electrocatalytic and photoelectrocatalytic pathways,offering promising solutions to the plastic waste crisis and advancing sustainability in the plastics industry.

关键词： Plastic upcycling Electrocatalytic reaction Photoelectrocatalytic reaction Value-added product

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prenatal and postnatal factors associated with sudden infant death syndrome:an umbrella review of meta-analyses

引用

World Journal of Pediatrics 2024年第5期20卷 451-460页

作者： tae Hyeon Kim Hyeri Lee Selin Woo Hayeon Lee Jaeyu park Guillaume Fond Laurent Boyer jong Woo Hahn Jiseung Kang Dong Keon Yon Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea CEReSS-Health Service Research and Quality of Life Center Assistance Publique des Hôpitaux de MarseilleAix-Marseille UniversityMarseilleFrance Department of Pediatrics Seoul National University College of MedicineSeoulSouth Korea Department of Pediatrics Seoul National University Bundang HospitalSeongnamSouth Korea Department of Anesthesia Critical Care and Pain MedicineMassachusetts General Hospital14913th StreetRoom 4140CharlestownBostonMAUSA Division of Sleep Medicine Harvard Medical SchoolBostonMAUSA Department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-roDongdaemun-guSeoul02447South Korea Department of Precision Medicine Kyung Hee University College of MedicineSeoulSouth Korea

Background Comprehensive quantitative evidence on the risk and protective factors for sudden infant death syndrome(SIDS)effects is *** investigated the risk and protective factors related to *** We conducted an umbrella review of meta-analyses of observational and interventional studies assessing SIDS-related ***/MEDLINE,Embase,EBSCO,and Google Scholar were searched from inception until January 18,*** extraction,quality assessment,and certainty of evidence were assessed by using A Measurement Tool Assessment Systematic Reviews 2 following PRISMA *** to observational evidence,credibility was graded and classified by class and quality of evidence(CE;convincing,highly suggestive,suggestive,weak,or not significant).Our study protocol was registered with PROSPERO(CRD42023458696).The risk and protective factors related to SIDS are presented as equivalent odds ratios(eORs).Results We identified eight original meta-analyses,including 152 original articles,covering 12 unique risk and protective factors for SIDS across 21 countries/regions and five *** risk factors,including prenatal drug exposure[eOR=7.84(95%CI=4.81–12.79),CE=highly suggestive],prenatal opioid exposure[9.55(95%CI=4.87–18.72),CE=suggestive],prenatal methadone exposure[9.52(95%CI=3.34–27.10),CE=weak],prenatal cocaine exposure[4.38(95%CI=1.95–9.86),CE=weak],prenatal maternal smoking[2.25(95%CI=1.95–2.60),CE=highly suggestive],postnatal maternal smoking[1.97(95%CI=1.75–2.22),CE=weak],bed sharing[2.89(95%CI=1.81–4.60),CE=weak],and infants found with heads covered by bedclothes after last sleep[11.01(95%CI=5.40–22.45),CE=suggestive],were *** the other hand,three protective factors,namely,breastfeeding[0.57(95%CI=0.39–0.83),CE=non-significant],supine sleeping position[0.48(95%CI=0.37–0.63),CE=suggestive],and pacifier use[0.44(95%CI=0.30–0.65),CE=weak],were also *** Based on the evidence,we propose several risk and protecti

关键词： Infant Protective factor Risk factor Sudden infant death syndrome Umbrella review

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Extracellular vesicles for neural regeneration after spinal cord injury

引用

Neural Regeneration Research 2024年第3期19卷 491-492页

作者： Young-Ju Lim Wook-tae park Gun Woo Lee Department of Orthopedic Surgery Yeungnam University Medical CenterYeungnam University College of MedicineDaeguKorea

What is spinal cord injury:Spinal cord injury(SCI)is the damage to the structure of the bundles of cells and nerves that communicate signals from the brain to the body and *** pathology of SCI includes both primary and secondary injuries(Morales et al.,2016).Physical forces such as compression,shearing,contusion,and tearing are major causes of primary injury in *** are two main processes in primary injury:acute and *** acute phase includes traumatic disruption of axons and hemorrhage of the blood vessels around the spinal *** injury to the vessels can lead to increased edema within the neural and cord tissues,susceptibility to infiltration by microglia and astrocytes,excitotoxicity,and ***,disruption of the blood-spinal cord barrier results in the release of inflammatory cytokines from specific cells and vessels.

关键词： acute injuries nerves

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

用农作物秸秆高效生物合成人造淀粉和单细胞蛋白

引用

Science Bulletin 2023年第2期68卷 214-223,M0004页

作者：徐欣欣张伟游淳范超纪王莉 jong-tae park Jiyun Kwak 陈红歌张以恒马延和 Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China Department of Food Science and Technology Chungnam National UniversityDaejeon 34134Republic of Korea College of Life Sciences Henan Agricultural UniversityZhengzhou 450002China

全球人口快速增长和气候变化正在引发可能的粮食危机.本研究开发了一种利用现有且丰富的农业废弃物(秸秆)高效合成人造淀粉和微生物蛋白的新技术.利用没有辅酶的体外多酶分子机器和酿酒酵母进行一锅法生物转化,将预处理玉米秸秆中的纤... 详细信息

全球人口快速增长和气候变化正在引发可能的粮食危机.本研究开发了一种利用现有且丰富的农业废弃物(秸秆)高效合成人造淀粉和微生物蛋白的新技术.利用没有辅酶的体外多酶分子机器和酿酒酵母进行一锅法生物转化,将预处理玉米秸秆中的纤维素进行酶水解合成人造淀粉,同时在有氧条件下发酵生产微生物蛋白.低成本去除β-葡萄糖糖苷酶的商业化纤维素酶以及在酿酒酵母细胞表面展示骨架蛋白用于固定淀粉磷酸化酶和纤维二糖磷酸化酶,构成一个多酶分子机器与酵母的复合体系,从而实现稀酸预处理秸秆的高效纤维素水解;利用纤维素水解中间产物的底物穿梭效应(从纤维素到微生物),快速消除葡萄糖对纤维素酶的产物抑制,比富含商业β-葡萄糖苷酶的纤维素酶混合物表现出更好的纤维素水解速率.动物实验结果显示,人造直链淀粉摄入引起缓慢平缓的血糖水平变化,表明直链淀粉作为预防肥胖和糖尿病的健康食品的应用前景.利用农业废弃物资源高效生物合成人造淀粉和微生物蛋白是解决粮食危机,实现农业可持续发展的重要途径之一.

关键词：直链淀粉微生物蛋白产物抑制纤维素水解淀粉磷酸化酶粮食危机动物实验结果单细胞蛋白

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：