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Dwindling in the mountains: Description of a critically endangered and microendemic Onychodactylus species(Amphibia, Hynobiidae) from the Korean Peninsula

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Zoological Research 2022年第5期43卷 750-755页

作者： Amael Borzee Yucheol Shin Nikolay APoyarkov jong Yoon Jeon hae Jun baek Chang Hoon Lee Junghwa An Yoon Jee Hong Mi-Sook Min Laboratory of Animal Behaviour and Conservation College of Biology and the EnvironmentNanjing Forestry UniversityNanjingJiangsu 210037China Department of Biological Sciences School of Natural ScienceKangwon National UniversityChuncheon 24341Republic of Korea Department of Vertebrate Zoology Biological FacultyM.V.Lomonosov Moscow State UniversityMoscow 119234Russia Research Institute for Veterinary Science College of Veterinary MedicineSeoul National UniversitySeoul 08826Republic of Korea Animal Resources Division National Institute for Biological ResourcesIncheon 22689Republic of Korea

DEAR EDITOR,Species that are not formally described are generally not targets for conservation,regardless of their threatened *** habitat degradation has increased over the past several decades in the Republic of Kore... 详细信息

关键词： habitat endangered mountains

Nanostructured hafnium-doped strontium oxide film for homeotropic/homogeneous convertible liquid crystal alignment depending on the curing temperature

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International Journal of Smart and Nano Materials 2022年第4期13卷 597-611页

作者： Dong Hyun Kim Dong wook Lee Jin Young Oh jonghoon Won hae-Chang Jeong Dae-Shik Seo IT Nano Electronic Device Laboratory Department of Electrical and Electronic EngineeringYonsei UniversitySeoulRepublic of Korea Department of Smart Manufacturing Engineering Changwon National UniversityChangwonGyeongnamRepublic of Korea Department of Electrical Electronic and Control Engineering Changwon National UniversityChangwonGyeongnamRepublic of Korea

A hafnium strontium oxide(HfSrO)liquid crystal(LC)alignment film was efficiently created through brush coating,and its ability to change the LC alignment direction was confirmed.A brush was applied to HfSrO sol coated on an indium-tin oxide substrate,after which the coating was solidified at var-ious curing *** was confirmed that a directional micro/nanostructure was formed above 280°C due to the shear stresses caused by the movement of the brush *** chemical changes were analyzed by using X-ray photoelectron spectroscopy and contact angle *** the curing temperature increased,the prevalence of oxygen bonds increased and the contact angle decreased,thereby increasing the surface *** anisotropic boundary of the micro-grooves and the van der Waals forces due to an increase in surface energy changed the alignment direction of LC mole-cules from vertical to horizontal,as verified through polarized optical microscopy and pretilt angle ***,the efficiency of the brush-coating method,which dramatically simplifies the LC alignment film process,was *** homeotropic/homogeneous LC alignment property of the HfSrO film produced through brush coating depending on the curing temperature provides an innovative approach for LC alignment.

关键词： Brush coating nanostructure solution process liquid crystal alignment

Silent advanced large cell neuroendocrine carcinoma with synchronous adenocarcinoma of the colon:A case report

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World Journal of Gastrointestinal Oncology 2022年第11期14卷 2266-2272页

作者： Hyeon Seok baek Sang wook Kim Soo Teik Lee Ho Sung Park Seung Young Seo Department of Internal Medicine Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University HospitalJeonju-si 56445Jeollabuk-doSouth Korea Department of Pathology Jeonbuk National University Medical SchoolJeonjusi 56445Jeollabuk-doSouth Korea

BACKGROUND Large cell neuroendocrine carcinoma(LCNEC)accounts for about 0.25%of colorectal cancer ***,synchronous LCNEC and adenocarcinoma coexistence in the colon is very *** are usually aggressive and have a poor ***,colorectal LCNEC patients complain of abdominal symptoms such as pain,diarrhea or hematochezia because it is often diagnosed as an advanced disease that accompanies metastatic *** SUMMARY We describe a case of relatively asymptomatic synchronous LCNEC and colon adenocarcinoma.A 62-year-old male patient visited our hospital due to anemia detected by a local health *** did not complain of melena,hematochezia or abdominal *** examination was unremarkable and his abdomen was soft,nontender and nondistended with no palpable *** tests revealed anemia with hemoglobin 5.1 g/*** revealed an ulcerofungating lesion in the ascending colon and about a 1.5 cm-sized large sessile polyp in the sigmoid *** biopsy of the ascending colon lesion revealed the ulcerofungating mass that was LCNEC and endoscopic mucosal resection at the sigmoid colon lesion showed a large polypoid lesion that was *** liver,lung,bone and lymph nodes metastasis was found on chest/abdominal computed tomography and positron emission *** patient was diagnosed with advanced colorectal LCNEC with liver,lung,bone and lymph node metastasis(stage IV)and synchronous colonic adenocarcinoma *** this case,no specific symptom except anemia was observed despite the multiple *** patient refused systemic chemotherapy and was discharged after *** We report a case of silent LCNEC of the colon despite the advanced state and synchronous adenocarcinoma.

关键词： Large cell neuroendocrine carcinoma Colon Synchronous Adenocarcinoma Case report

Kinetics modeling for the mixed reforming of methane over Ni-CeO_2/MgAl_2O_4 catalyst

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Journal of Natural Gas Chemistry 2011年第1期20卷 9-17页

作者： Hye Jin Jun Myung-June Park Seung-Chan baek jong wook Bae Kyoung-Su Ha Ki-Won Jun Department of Chemical Engineering Ajou University Petroleum Displacement Technology Research Center Korea Research Institute of Chemical Technology (KRICT)

Kinetics model was developed for the mixed （steam and dry） reforming of methane, which is useful for the control of H2/CO ratio. The equilibrium constants of reaction rate were determined using the experimental equilibrium data at different reaction temperatures, while the forward reaction rate constants were estimated using the experimental data under non-equilibrium （high inert fraction and high space velocity） conditions. The comparison between calculated and experimental data clearly showed that the developed model described satisfactorily, and further analysis using the parametric sensitivity determined the wall temperature and CO2 fraction in the feed gas as effective parameters for the manipulation of CH4 conversion and H2/CO ratio of synthesis gas under the equilibrium condition. Meanwhile, the inert fraction, rather than the residence time, was selected as additional parameter under non-equilibrium condition.

关键词： mixed reforming nickel-based catalyst kinetics modeling parameter estimation parametric sensitivity

Efficacy of horse oil on lipopolysaccharide-induced inflammation in human keratinocytes

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Journal of Traditional Chinese Medicine 2021年第3期41卷 355-359页

作者： In wook Kim Hyo-Soon Jeong Hye-Young Yun Kwang Jin baek Nyoun Soo kwon Dong-Seok Kim Department of Biochemistry Chung-Ang University College of MedicineSeoul 06974Republic of Korea

OBJECTIVE: To investigate the efficacy of horse oil on lipopolysaccharide(LPS)-induced inflammation in human ***: Western blot analysis was performed to measure the expression of cyclooxygenase-2(COX-2) and IκBα. ELISA was used to analyze prostaglandin E2(PGE2) ***: Horse oil decreased LPS-induced COX-2 and PGE2 levels in a dose-dependent manner. Nuclear factor-kappa B(NF-κB) plays a key role in the expression of inflammatory cytokines and mediators. Therefore, we investigated the influence of horse oil on the NF-κB signaling pathways. Horse oil inhibited translocation of NF-κB from the cytosol to the nucleus. Furthermore, LPS-induced degradation of IκBα was recovered by horse oil. The activation of p38 mitogen-activated protein kinase(MAPK) reportedly induces degradation of IκBα In agreement with this, LPS activated p38 MAPK and caused IκBα degradation. Conversely, horse oil inhibited LPS-induced p38 MAPK activation and IκBαdegradation. In addition, a specific p38 MAPK inhibitor, SB203580, blocked IκBα ***: Horse oil decreased COX-2 and PGE2 by inhibiting p38 MAPK activation, IκBα degradation, and the translocation of NF-κB.

关键词： horse oil inflammation keratinocytes NF-kappa B cyclooxygenase 2 mitogen-activated protein kinase lipopolysaccharides dinoprostone

Molecular phylogenetic status of Siberian roe deer(Capreolus pygargus) based on mitochondrial cytochrome b from Jeju Island in Korea

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Chinese Science Bulletin 2014年第32期59卷 4283-4288页

作者： Yong-Su Park baek-Jun Kim Woo-Shin Lee jong-Taek Kim Tae-wook Kim Hong-Shik Oh Jangsu Endangered Species Restoration Team Jangsu CountyJeonbuk 176-7 Republic of Korea Department of Climate and Ecology National Institute of Ecology Seocheon 325-813 Republic of Korea Department of Forest Science Seoul National UniversitySeoul 151-192 Republic of Korea School of Veterinary Medicine Kangwon National UniversityChuncheon Gangwon 200-701 Republic of Korea Department of Science Education Jeju National UniversityJeju 690-750 Republic of Korea

In order to elucidate the genetic diversity and taxonomic status of Siberian roe deer(Capreolus pygargus)from the Korean peninsula,partial sequences of the mitochondrial cytochrome b gene were *** collected 57 roe deer samples from Mainland and Jeju Island between July 2004 and June 2009.A total of 50 sequences(1,070 bp)were obtained,and seven haplotypes were *** haplotypes were found from Mainland,and two were discovered from Jeju *** genetic diversity was lower in the Jeju Island population than in the Mainland *** addition,both the consensus neighbor-joining tree and maximum parsimony tree showed an identical topology between the Mainland and Jeju Island *** on the results,two subspecies of the Korean roe deer were *** roe deer in Jeju Island showed a distinct difference in the cytochrome b gene compared with other Siberian roe deer,being aunique native species inhabiting only Jeju Island in *** Siberian roe deer in Jeju Island can be classified at subspecies level,the new subspecies in Jeju was named Capreolus pygargus jejuensis in this *** this new subspecies,reasonable conservation and management effort is needed in the future.

关键词：线粒体细胞色素b基因济州岛系统发育地位矮鹿韩国狍遗传多样性分子

Sex-specific effects of social networks on the prevalence, awareness, and control of hypertension among older Korean adults

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Journal of Geriatric Cardiology 2016年第7期13卷 580-586页

作者： Jiwon baek Nam wook Hur Hyeon Chang Kim Yoosik Youm Department of Sociology Yonsei University College of Social Sciences Seoul South Korea Department of Preventive Medicine Yonsei University College of Medicine Seoul South Korea

BackgroundHypertension 是在更老的成年人之中的普通长期的疾病，并且与医药复杂并发症和死亡被联系。试图在更旧的 *** 朝鲜语聚会生活，健康，和老化工程(KSHAP ) 之中在高血压的流行，了解，和控制上检验社会网络特征的效果的这研... 详细信息

BackgroundHypertension 是在更老的成年人之中的普通长期的疾病，并且与医药复杂并发症和死亡被联系。试图在更旧的 *** 朝鲜语聚会生活，健康，和老化工程(KSHAP ) 之中在高血压的流行，了解，和控制上检验社会网络特征的效果的这研究会见了 814 ≥；从在 2011 年 12 月和 2012 年 3 月之间的一个农村镇区的 60 岁的居民和他们的配偶(反应率：95%) 。我们从 595 个参加者评估了数据。Multivariate 逻辑回归模型被用来在观察强壮的性特定的网络在高血压的流行，了解，和控制上完成的 *** 上估计网络特征的效果。在老妇人之中，网络密度与高血压了解被联系[机会比率(或) ：2.63， 95% 信心间隔(CI ) ：1.03-5.37 ] 并且控制(或：1.72；95% CI：0.94-3.13 ) 。在老人之中，大网络与高血压的更低的流行被联系(或：0.75；95% CI：0.58-0.96 ) 。比作老妇人，有粗糙的网络的老人展出了更好的高血压了解(或：0.37；95% CI：0.14-0.95 ) 并且控制(或：0.42；95% CI：0.19-0.91 ) 。网络尺寸为高血压控制与密度交往了(P = 0.051 ) ，与与被联系的控制高血压大并且功课 *** 大网络为高血压与更低的风险被联系，并且一个粗糙的网络在老人之中与高血压了解和控制被联系。有稠密的网络的老妇人是最可能的展出高血压了解和控制。

关键词：网络特性高血压老年人控制率患病率异性性别可信区间

Virtual Mold Technique in Thermal Stress Analysis during Casting Process

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Journal of Materials Science & Technology 2008年第3期24卷 359-363页

作者： Si-Young Kwak Jae-wook baek Jeong-Ho Nam Jeong-Kil Choi E-Design Center Korea Institute of Industrial Technology Department of Virtual Engineering Korea University of Science & Technology

It is important to analyse the casting product and the mold at the same time considering thermal contraction of the casting and thermal expansion of the mold. The analysis considering contact of the casting and the mold induces the precise prediction of stress distribution and the defect such as hot tearing. But it is difficult to generate FEM mesh for the interface of the casting and the mold. Moreover the mesh for the mold domain spends lots of computational time and memory for the analysis due to a number of meshes. Consequently we proposed the virtual mold technique which only uses mesh of the casting part for thermal stress analysis in casting process. The spring bar element in virtual mold technique is used to consider the contact of the casting and the mold. In general, a volume of the mold is much bigger than that of casting part, so the proposed technique decreases the number of mesh and saves the computational memory and time greatly. In this study, the proposed technique was verified by the comparison with the traditional contact technique on a specimen. And the proposed technique gave satisfactory results.

关键词： Casting process Thermal stress analysis Virtual mold

Risk prediction platform for pancreatic fistula after pancreatoduodenectomy using artificial intelligence

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World Journal of Gastroenterology 2020年第30期26卷 4453-4464页

作者： In Woong Han Kyeongwon Cho Youngju Ryu Sang Hyun Shin Jin Seok Heo Dong wook Choi Myung Jin Chung Oh Chul kwon baek Hwan Cho Department of Surgery Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Medical Artificial Intelligence Research Center Department of Medical Device Management and ResearchSAIHSTSamsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Department of Radiology Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Artificial Intelligence Research Center Medical DataBase IncorporatedSeoul 06048South Korea

BACKGROUND Despite advancements in operative technique and improvements in postoperative managements,postoperative pancreatic fistula(POPF)is a life-threatening complication following pancreatoduodenectomy(PD).There are some reports to predict POPF preoperatively or intraoperatively,but the accuracy of those is *** intelligence(AI)technology is being actively used in the medical field,but few studies have reported applying it to outcomes after *** To develop a risk prediction platform for POPF using an AI *** Medical records were reviewed from 1769 patients at Samsung Medical Center who underwent PD from 2007 to 2016.A total of 38 variables were inserted into AI-driven *** algorithms tested to make the risk prediction platform were random forest(RF)and a neural network(NN)with or without recursive feature elimination(RFE).The median imputation method was used for missing *** area under the curve(AUC)was calculated to examine the discriminative power of algorithm for POPF *** The number of POPFs was 221(12.5%)according to the International Study Group of Pancreatic Fistula definition *** median imputation,AUCs using 38 variables were 0.68±0.02 with RF and 0.71±0.02 with *** maximal AUC using NN with RFE was *** risk factors for POPF were identified by AI algorithm:Pancreatic duct diameter,body mass index,preoperative serum albumin,lipase level,amount of intraoperative fluid infusion,age,platelet count,extrapancreatic location of tumor,combined venous resection,co-existing pancreatitis,neoadjuvant radiotherapy,American Society of Anesthesiologists’score,sex,soft texture of the pancreas,underlying heart disease,and preoperative endoscopic biliary *** developed a web-based POPF prediction platform,and this application is freely available at http://*** This study is the first to predict POPF with multiple risk factors using *** platform is reli

关键词： Postoperative pancreatic fistula Pancreatoduodenectomy Neural networks Recursive feature elimination