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Journal of Integrative Plant Biology 2022年第3期64卷 625-631页

作者： min Yong Ahn Dong Hye Seo Woo Taek kim Department of Systems Biology Division of Life ScienceYonsei UniversitySeoul 03722Korea Institute of Life Science and Biotechnology Yonsei UniversitySeoul 03722Korea

The mechanism regulating proteasomal activity under proteotoxic stress conditions remains ***,we showed that arsenite-induced proteotoxic stress resulted in upregulation of Arabidopsis homologous PUB22 and PUB23 U-boxE3 ubiquitin ligases and that pub22 pub23 double mutants displayed arsenite-insensitive seed germination and root growth ***22/PUB23 downregulated 26 S proteasome activity by promoting the dissociation of the 19 S regulatory particle from the holo-proteasome complex,resulting in intracellular accumulation of UbG76 VGFP,an artificial substrate of the proteasome complex,and insoluble poly-ubiquitinated *** results suggest that PUB22/PUB23 play a critical role in arsenite-induced proteotoxic stress response via negative regulation of 26 S proteasome integrity.

关键词： Arabidopsis thaliana proteotoxic stress sodium arsenite U-box E3 ligases PUB22/23 26S proteasome complex

GRU-based Buzzer Ensemble for Abnormal Detection in Industrial Control Systems

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Computers, Materials & Continua 2023年第1期74卷 1749-1763页

作者： Hyo-Seok kim Chang-Gyoon Lim Sang-Joon Lee Yong-min kim Interdisciplinary Program of Information Security Chonnam National UniversityGwangju61186Korea Major in Computer Engineering Chonnam National UniversityYeosu59626Korea School of Business Administration Chonnam National UniversityGwangju61186Korea Department of Electronic Commerce Chonnam National UniversityYeosu59626Korea

Recently,Industrial Control Systems(ICSs)have been changing from a closed environment to an open environment because of the expansion of digital transformation,smart factories,and Industrial Internet of Things(IIoT).Since security accidents that occur in ICSs can cause national confusion and human casualties,research on detecting abnormalities by using normal operation data learning is being actively *** single technique proposed by existing studies does not detect abnormalities well or provide satisfactory *** this paper,we propose a GRU-based Buzzer Ensemble for AbnormalDetection(GBE-AD)model for detecting anomalies in industrial control systems to ensure rapid response and process *** newly proposed ensemble model of the buzzer method resolves False Negatives(FNs)by complementing the limited range that can be detected in a single model because of the internal models composing *** the internal models remain suppressed for False Positives(FPs),GBE-AD provides better *** addition,we generated mean prediction error data in GBE-AD and inferred abnormal processes using soft and hard *** confirmed that the detection model’s Time-series Aware Precision(TaP)suppressed FPs at 97.67%.The final performance was 94.04%in an experiment using anHIL-basedAugmented ICS(HAI)Security Dataset(ver.21.03)among public datasets.

关键词： Industrial control system abnormal detection ensemble learning HAI dataset

User Recognition System Based on Spectrogram Image Conversion Using EMG Signals

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Computers, Materials & Continua 2022年第7期72卷 1213-1227页

作者： Jae Myung kim Gyu Ho Choi min-Gu kim Sung Bum Pan Interdisciplinary Program in IT-Bio Convergence System Chosun UniversityGwangju61452Korea IT Research Institute Chosun UniversityGwangju61452Korea

Recently,user recognitionmethods to authenticate personal identity has attracted significant attention especially with increased availability of various internet of things(IoT)services through fifth-generation technology(5G)based mobile *** EMG signals generated inside the body with unique individual characteristics are being studied as a part of nextgeneration user recognition ***,there is a limitation when applying EMG signals to user recognition systems as the same operation needs to be repeated while maintaining a constant strength of muscle over ***,it is necessary to conduct research on multidimensional feature transformation that includes changes in frequency features over *** this paper,we propose a user recognition system that applies EMG signals to the short-time fourier transform(STFT),and converts the signals into EMG spectrogram images while adjusting the time-frequency resolution to extract multidimensional *** proposed system is composed of a data pre-processing and normalization process,spectrogram image conversion process,and final classification *** experimental results revealed that the proposed EMG spectrogram image-based user recognition system has a 95.4%accuracy performance,which is 13%higher than the EMGsignal-based *** a user recognition accuracy improvement was achieved by using multidimensional features,in the time-frequency domain.

关键词： EMG user recognition spectrogram CNN

Electrochemical characteristics of HVOF spray coated layer with WC-27NiCr and WC-10Co4Cr for Al bronze

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中国有色金属学会会刊：英文版 2012年第S3期22卷 753-759页

作者： min-su HAN Seung-jun LEE min-sung kim Seok-ki JANG Seong-jong kim Division of Marine Engineering Mokpo Maritime University

Among the environmentally friendly marine energies,tidal current power plants require low cost because they do not need to construct a large *** power is particularly reliable energy source because the power generation capacity is predictable regardless of weather or *** materials or stainless steel have been used as materials of blades for current power ***,their strength and welding performance generated many problems in field *** alloys with excellent cavitation resistance and corrosion resistance were applied as blade materials to improve the durability of copper *** were coated with WC-27NiCr and WC-10Co4Cr using the high velocity oxy-fuel (HVOF) *** metal spray coating technology has the advantage in terms of the selection of materials for cost effectiveness and environmental effects of corrosion because the properties of the coat layer can be controlled *** with WC-27NiCr and WC-10Co4Cr by HVOF,WC-27NiCr shows better corrosion resistance *** reason for this seems to be that corrosion resistance improves and a stable passive film forms due to the effects of Ni and Cr.

关键词： tidal power copper alloys HVOF coating corrosion resistance

Aqueous-processable,naphthalene diimide-based polymers for eco-friendly fabrication of high-performance,n-type organic electrolyte-gated transistors

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Science China Chemistry 2022年第5期65卷 973-978页

作者： Dahyun Jeong min Je kim Seungjin Lee Jin-Woo Lee Youngwoong kim Hyeong Jun kim Jeong Ho Cho Bumjoon J.kim Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Chemical and Biomolecular Engineering Sogang UniversitySeoul 04107Republic of Korea

Organic electrolyte-gated transistors(OEGTs) have the benefits of low power consumption and large current ***,the electrical performance of n-type OEGTs lags far behind that of p-type *** this study,we design a series of polymers,P(NDITEG-T) and P(NDIMTEG-T),comprising a naphthalene diimide backbone for n-type charge transport and oligo(ethylene glycol)(OEG) side chains for high ionic conductivity and eco-friendly solution *** incorporation of the OEG chain facilitates the electrochemical doping of the semiconductor by ions to realize high-performance,n-type ***,in OEGTs,P(NDITEG-T) achieves a high electron mobility of 1.0 × 10^(-1) cm^(2) V^(-1) s^(-1),which represents the highest value reported for solution-processed,n-type *** is noted that the fabrication of the OEGTs is achieved by solution processing with eco-friendly ethanol/water mixtures in virtue of the hydrophilic OEG *** work demonstrates the molecular design of the P(NDITEG-T) polymer and its significant ability to produce aqueous-processable,high-performance,and n-type OEGTs.

关键词： organic electrolyte-gated transistors n-type transistors oligo(ethylene glycol)polymers eco-friendly solution process high electron mobility

The role of extracellular vesicles in animal reproduction and diseases

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Journal of Animal Science and Biotechnology 2022年第6期13卷 1634-1656页

作者： Sangiliyandi Gurunathan min-Hee Kang Hyuk Song Nam Hyung kim Jin-Hoi kim Department of Stem Cell and Regenerative Biotechnology Konkuk UniversitySeoul 05029Korea Guangdong Provincial Key Laboratory of Large Animal models for Biomedicine Wuyi UniversityJiangmen 529020China

Extracellular vesicles(EVs)are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication,both in normal physiology and in pathological *** can transfer functional proteins and genetic information to alter the phenotype and function of recipient cells,which undergo different changes that positively affect their structural and functional *** fluids are enriched with several subpopulations of EVs,including exosomes,microvesicles(MVs),and apoptotic bodies carrying several cargoes,such as lipids,proteins,and nucleic *** associated with the reproductive system are actively involved in the regulation of different physiological events,including gamete maturation,fertilization,and embryo and fetal *** can influence follicle development,oocyte maturation,embryo production,and endometrial-conceptus *** loaded with cargoes are used to diagnose various diseases,including pregnancy disorders;however,these are dependent on the type of cell of origin and pathological ***-derived microRNAs(miRNAs)and proteins in the placenta regulate inflammatory responses and trophoblast invasion through intercellular delivery in the placental *** review presents evidence regarding the types of extracellular vesicles,and general aspects of isolation,purification,and characterization of EVs,particularly from various types of ***,we discuss EVs as mediators and messengers in reproductive biology,the effects of EVs on placentation and pregnancy disorders,the role of EVs in animal reproduction,in the male reproductive system,and mother and embryo *** addition,we emphasize the role of microRNAs in embryo implantation and the role of EVs in reproductive and therapeutic ***,we discuss the future perspectives of EVs in reproductive biology.

关键词： Embryos Extracellular vesicles Implantation MicroRNA Pregnancy disorders

Microstructural characteristics and low-cycle fatigue properties of AZ91 and AZ91-Ca-Y alloys extruded at different temperatures

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Journal of Magnesium and Alloys 2023年第3期11卷 892-902页

作者： Ye Jin kim Young min kim Jun Ho Bae Soo-Hyun Joo Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Advanced Metals Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Engineering Dankook UniversityCheonan 31116Republic of Korea

The commercial AZ91 alloy and nonflammable SEN9(AZ91-0.3Ca-0.2Y,wt%)alloy are extruded at 300°C and 400°*** microstructure,tensile and compressive properties,and low-cycle fatigue(LCF)properties are investigated,with particular focus on the influence of the extrusion *** the AZ91 and SEN9 materials extruded at 300°C(300-materials),numerous fine Mg_(17)Al_(12)particles are inhomogeneously distributed owing to localized dynamic precipitation during extrusion,unlike those extruded at 400°C(400-materials).These fine particles suppress the coarsening of recrystallized grains,decreasing the average grain size of *** the four extruded materials have considerably different microstructures,the difference in their tensile yield strengths is insignificant because strong grain-boundary hardening and precipitation hardening effects in 300-materials are offset almost completely by a strong texture hardening effect in ***,owing to their finer grains and weaker texture,300-materials have higher compressive yield strengths *** the LCF tests,{10-12}twinning is activated at lower stresses in 400-materials than in *** the fatigue damage accumulated per cycle is smaller in 400-materials,they have longer fatigue lives than those of 300-materials.A fatigue life prediction model for the investigated materials is established on the basis of the relationship between the total strain energy density(ΔW_(t))and the number of cycles to fatigue failure(N_(f)),and it is expressed through a simple equation(ΔW_(t)=10·N_(f)-0.59).This model enables fatigue life prediction of both the investigated alloys regardless of the extrusion temperature and strain amplitude.

关键词： AZ91-Ca-Y Extrusion temperature Microstructure Low-cycle fatigue Fatigue life prediction model

Harnessing novel engineered feeder cells expressing activating molecules for optimal expansion of NK cells with potent antitumor activity

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Cellular & Molecular Immunology 2022年第2期19卷 296-298页

作者： Bokyung min Bitna Yang You-Sun kim Gyeong min Park HyunAh kim Hyojin kim Eun-Ji kim Yu Kyeong Hwang Eui-Cheol Shin Sungyoo Cho BioMedical Science and Engineering Interdisciplinary Program KAISTDaejeonKorea Cell Therapy Research Center GC LabCellYonginKorea Laboratory of Immunology and Infectious Diseases Graduate School of Medical Science and EngineeringKAISTDaejeonKorea

Natural killer(NK)cells play an important role in the antitumor immune response as the major cytotoxic lymphocytes in the innate immune *** cells without any genetic modifications have been used for both autologous and allogeneic ***,many reports have suggested that allogeneic NK cells can reduce the recurrence of disease and improve survival through a graft-versus-leukemia effect without GVHD[1,2].

关键词： killer expressing optimal

Intelligent Risk-Identification Algorithm with Vision and 3D LiDAR Patterns at Damaged Buildings

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Intelligent Automation & Soft Computing 2023年第5期36卷 2315-2331页

作者： Dahyeon kim Jiyoung min Yongwoo Song Chulsu kim Junho Ahn Computer Information Technology Korea National University of TransportationChungju27469Korea Department of Railway Vehicle System Engineering Korea National University of TransportationUiwang16106Korea

Existingﬁreﬁghting robots are focused on simple storage orﬁre sup-pression outside buildings rather than detection or *** a large number of robots using expensive equipment is *** study aims to increase the efﬁciency of search and rescue operations and the safety ofﬁreﬁgh-ters by detecting and identifying the disaster site by recognizing collapsed areas,obstacles,and rescuers on-site.A fusion algorithm combining a camera and three-dimension light detection and ranging(3D LiDAR)is proposed to detect and loca-lize the interiors of disaster *** algorithm detects obstacles by analyzingﬂoor segmentation and edge patterns using a mask regional convolutional neural network(mask R-CNN)features model based on the visual data collected from a parallelly connected camera and 3D *** as objects are detected using you only look once version 4(YOLOv4)in the image data to localize persons requiring *** point cloud data based on 3D LiDAR cluster the objects using the density-based spatial clustering of applications with noise(DBSCAN)clustering algorithm and estimate the distance to the actual object using the center point of the clustering *** proposed artiﬁcial intelligence(AI)algorithm was veriﬁed based on individual sensors using a sensor-mounted robot in an actual building to detectﬂoor surfaces,atypical obstacles,and persons requiring ***,the fused AI algorithm was comparatively veriﬁed.

关键词： Three-dimension light detection and ranging vision risk identiﬁcation damaged building robot

Improvement of hydrogen embrittlement and stress corrosion cracking by annealing for Al-4.4Mg-0.6Mn alloy

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 17-22页

作者： Seong-jong kim min-Su HAN Seong-Kweon kim Seok-Ki JANG Division of Marine Engineering Mokpo National Maritime University Media Engineering Seoul National University of Technology

With no annealing treatment, cathodic polarization trends in 5083F Al alloy revealed concentration polarization and activation polarization. However, the annealed specimens have lower current densities at corrosion protection potential compared to the non-annealed specimen. The results of SSRTs conducted in seawater at the applied potential range of -1.8 V to -0.5 V indicated that the maximum tensile strength, elongation, and time-to-fracture had high values at applied potentials of –0.7 to –1.4 V. The maximum tensile strength, elongation, and time-to-fracture decreased when the potential values were beyond this range in either anodic or cathodic direction. In general, the increased shear lip caused by annealing treatment indicates elongation. Time-to-fracture would likely increase with elongation. Potentials between –0.5 V to –0.6 V were found to be in the region of stress corrosion cracking. The corrosion protection zone was determined to be –0.7 V to –1.4 V because these potential ranges produced good mechanical properties. Potential less than –1.4 V produced a fractured surface with a mixture of dimples (ductile fractures) and a quasi-cleavage pattern resulting from the effects of hydrogen gas.

关键词：应力腐蚀开裂退火处理合金氢脆浓度极化阴极极化保护电位拉伸强度