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Surgical treatment outcomes of primary hepatic sarcomas: A singlecenter experience

World Journal of Hepatology 2021年第5期13卷 584-594页

作者： Sang Jin kim Jinsoo Rhu jong man kim Gyu Seung Choi Jae-Won Joh Department of Surgery Korea University College of MedicineSeoulRepublic of KoreaDivision of Hepatobiliopancreas and Transplant SurgeryKorea University Ansan HospitalAnsan 15355South Korea Department of Surgery Samsung Medical CenterSeoul 06351South Korea

BACKGROUND Primary hepatic sarcoma is a rare tumor originated from mesenchymal *** are various pathologic types of primary hepatic sarcoma and the treatment outcome of this tumor was usually *** hepatocellular carcinoma,outcome of primary hepatic sarcoma is not well-known due to it’s ***,with development of medical technology,surgical treatment may lead to better *** To investigate the surgical outcomes of primary hepatic sarcoma,we gathered and analyzed the cases of a single *** From August 2001 to September 2016,a total of nine patients were surgically treated for primary hepatic sarcoma after exclusion of cases with open and closure,early loss to follow-up and sarcomatoid hepatocellular carcinoma and sarcomatoid cholangiocellular *** characteristics,tumor characteristics such as tumor pathology,size and number,surgical and adjuvant treatments were *** recurrence,and patient survival were analyzed with retrospective *** The enrolled participants included five patients with angiosarcoma and four patients with undifferentiated *** patients experienced tumor recurrence at a median of 52 post-operative *** two patients survived and the 5-year survival rate was 29.6%.One patient with angiosarcoma who received central hepatectomy for primary tumor and received radiofrequency ablation for recurrent tumor still lives for 11 *** patient with undifferentiated sarcoma received *** for primary tumor followed by chemotherapy and radiation therapy still lives around 30 mo even though she got additional operation for recurrent *** patients who received living donor liver transplantation due to angiosarcoma *** adjuvant therapy was associated with survival gain(P=0.002).CONCLUSION Patients with primary hepatic sarcoma may gain survival benefit with surgical resection followed by adjuvant therapy,even though the outcome remains relatively poor

关键词： Liver Angiosarcoma Undifferentiated sarcoma Operation Survival Recurrence

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Hepatic resection vs percutaneous radiofrequency ablation of hepatocellular carcinoma abutting right diaphragm

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World Journal of Gastrointestinal Oncology 2019年第3期11卷 227-237页

作者： Kyoung Doo Song Hyo Keun Lim Hyunchul Rhim Min Woo Lee Tae Wook Kang Yong Han Paik jong man kim Jae-Won Joh Department of Radiology Samsung Medical Center Sungkyunkwan University School of Medicine Department of Radiology Samsung Medical Center Sungkyunkwan University School of Medicine Department of Health Sciences and Technology SAIHSTSungkyunkwan University Department of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Department of Surgery Samsung Medical Center Sungkyunkwan University School of Medicine

BACKGROUND It is usually difficult to adequately conduct percutaneous ultrasound-guided radiofrequency(RF) ablation for hepatocellular carcinomas(HCCs) abutting the diaphragm. Our hypothesis was that the subphrenic location of HCC could have an effect on the long-term therapeutic outcomes after hepatic resection and RF *** To compare the long-term therapeutic outcomes of hepatic resection and percutaneous RF ablation for HCCs abutting the *** A total of 143 Child-Pugh class A patients who had undergone hepatic resection(n = 80) or percutaneous ultrasound-guided RF ablation(n = 63) for an HCC(≤ 3 cm) abutting the right diaphragm were included. Cumulative local tumor progression(LTP), cumulative intrahepatic distant recurrence(IDR), disease-free survival(DFS), and overall survival(OS) rates were estimated. Prognostic factors for DFS and OS were analyzed. Complications were *** The cumulative IDR rate, DFS rate, and OS rate for the hepatic resection group and RF ablation group at 5 years were "35.9% vs 65.8%", "64.1% vs 18.3%", and"88.4% vs 68.7%", respectively. Hepatic resection was an independent prognostic factor for DFS(P ≤ 0.001; hazard ratio, 0.352; 95%CI: 0.205, 0.605; with RF ablation as the reference category); however, treatment modality was not an independent prognostic factor for OS. The LTP rate was 46.6% at 5 years for the RF ablation group. The major complication rate was not significantly different between the groups(P = 0.630). The rate of occurrence of peritoneal seeding was higher in the RF ablation group(1.3% vs 9.5%, P = 0.044).CONCLUSION Although OS was not significantly different between patients who had gone hepatic resection or percutaneous RF ablation for HCCs abutting the diaphragm,DFS was better in the hepatic resection group.

关键词： Hepatic resection Radiofrequency ablation Hepatocellular carcinoma Diaphragm Treatment outcome

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Single hepatocellular carcinoma ≤ 3 cm in left lateral segment:Liver resection or radiofrequency ablation?

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World Journal of Gastroenterology 2014年第14期20卷 4059-4065页

作者： jong man kim Tae Wook Kang Choon Hyuck David Kwon Jae-Won Joh Justin Sangwook Ko Jae Berm Park Hyunchul Rhim Joon Hyeok Lee Sung Joo kim Seung Woon Paik Department of Surgery Samsung Medical CenterSungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science Samsung Medical CenterSungkyunkwan University School of Medicine Department of Anesthesiology and Pain Medicine Samsung Medical CenterSungkyunkwan University School of Medicine Division of Gastroenterology Department of MedicineSamsung Medical CenterSungkyunkwan University School of Medicine

AIM: To evaluate the long-term results of radiofrequency ablation (RFA) compared to left lateral sectionectomy (LLS) in patients with Child-Pugh class A disease for the treatment of single and small hepatocellular car... 详细信息

关键词： Small hepatocellular carcinoma Left lateral segment Radiofrequency ablation Liver resection Tumor recurrence Survival

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New-onset diabetes after adult liver transplantation in the Korean Organ Transplantation Registry (KOTRY) study

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Hepatobiliary Surgery and Nutrition 2020年第4期9卷 425-439页

作者： jong man kim Shin Hwang Kwang-Woong Lee Jae-Geun Lee Je Ho Ryu Bong-Wan kim Dong Lak Choi Young Kyoung You Dong-Sik kim Yang Won Nah Koo Jeong Kang Jai Young Cho Geun Hong In Seok Choi Hee Chul Yu Dongho Choi Myoung Soo kim 无 Department of Surgery Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea Department of Surgery Asan Medical CenterCollege of Medicine University of UlsanSouth Korea Department of Surgery Seoul National University College of MedicineSeoulSouth Korea Department of Surgery Yonsei University College of MedicineSeoulSouth Korea Department of Surgery Pusan National University College of MedicineBusanSouth Korea Department of Liver Transplantation and Hepatobiliary Surgery Ajou University School of MedicineSuwonSouth Korea Department of Surgery Catholic University of Daegu College of MedicineDaeguSouth Korea Department of Surgery College of MedicineCatholic University of KoreaSeoulSouth Korea Division of HBP Surgery and Liver Transplantation Department of SurgeryKorea University College of MedicineSeoulSouth Korea Department of Surgery Ulsan University HospitalUniversity of Ulsan College of MedicineUlsanSouth Korea Department of Surgery Keimyung University School of MedicineDaeguSouth Korea Department of Surgery Seoul National University Bundang HospitalSeoul National University College of MedicineSungnamSouth Korea Department of Surgery Ewha Woman’s University School of MedicineSeoulSouth Korea Department of Surgery Konyang University HospitalDaejonSouth Korea Department of Surgery Chonbuk National University School of MedicineJeonjuSouth Korea Department of Surgery Hanyang University College of MedicineSeoulSouth Korea The Korean Organ Transplantation Registry Study Group

Background:New-onset diabetes after transplantation(NODAT)is a serious complication following liver transplantation(LT).The present study aimed to investigate the incidence of and risk factors for NODAT using the Korean Organ Transplantation Registry(KOTRY)***:Patients with history of pediatric transplantation(age≤18 years),re-transplantation,multi-organ transplantation,or pre-existing diabetes mellitus were excluded.A total of 1,919 non-diabetic adult patients who underwent a primary LT between May 2014 and December 2017 were *** factors were identified using Cox regression ***:NODAT occurred in 19.7%(n=377)of adult liver transplant *** analysis showed steroid use,increased age,and high body mass index(BMI)in recipients,and implantation of a left-side liver graft was closely associated with NODAT in adult *** living donor liver transplant(LDLT)patients(n=1,473),open donor hepatectomy in the living donors,steroid use,small for size liver graft(graft to recipient weight ratio≤0.8),increased age,and high BMI in the recipient were predictive factors for *** use of antimetabolite and basiliximab induction reduced the incidence of NODAT in adult LT and in adult ***:Basiliximab induction,early steroid withdrawal,and antimetabolite therapy may prevent NODAT after adult *** BMI or advanced age in liver recipients,open donor hepatectomy in living donors,and small size liver graft can predict the occurrence of NODAT after adult LT or LDLT.

关键词： Diabetes living donors immunosuppression Asia

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Environmentally friendly hybrid coating prepared by electro-deposition method at various seawater conditions

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中国有色金属学会会刊：英文版 2009年第B9期19卷 110-113页

作者： Myeong-Hoon LEE Kyung-man MOON jong-Do kim Kang JUN Kwang-Ho kim Division of Marine System Engineering Korea Maritime University Dongsam-Dong Youngdo Busan 606-791 Korea National Core Research Center for Hybrid Materials Solution Pusan National University Busan 609-735 Korea

The formation mechanism of calcareous deposit films in seawater involves an increase in pH at the metal/solution interface due to cathodic reactions, a raised carbonate ion concentration at the interface and precipitation of inorganic deposits such as CaCO3, Mg(OH)2. Environmentally friendly hybrid calcareous deposit films were formed by an electrochemical technique on steel substrates in various solution environments. And the influence of dissolved gas on formation of calcareous deposit films was investigated by scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS) and X-ray diffractometry(XRD). Consequently, these results showed that formation of good overall calcareous deposited films by dissolved gas in seawater environments can be achieved by controlling the material composition and structure through effective use of electrochemical method.

关键词：海水混合环保电沉积扫描电子显微镜涂层制备溶液界面

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Synergistic passivation of MAPbI_(3) perovskite solar cells by compositional engineering using acetamidinium bromide additives

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Journal of Energy Chemistry 2021年第8期30卷 755-762,I0016页

作者： Kyungeun Jung Weon-Sik Chae Jae Won Choi Ki Chul kim man-jong Lee Department of Chemistry Konkuk University143-701 SeoulSouth Korea Department of Advanced Technology Fusion Konkuk University143-701 SeoulSouth Korea Analysis Research Division Daegu CenterKorea Basic Science Institute702-701 DaeguSouth Korea Division of Chemical Engineering Konkuk University05029 SeoulSouth Korea

For the global commercialization of highly efficient and stable perovskite solar cells(PSCs),it is necessary to effectively suppress the formation of various defects acting as nonradiative recombination sources in perovskite light-harvesting *** defects between the charge-selective layer and the perovskite are easily formed in the solution process used to fabricate perovskite *** addition,owing to the difference in thermal expansion coefficients between the substrate and the perovskite film,internal residual tensile stress inevitably occurs,resulting in increased nonradiative ***,a simple compositional engineering scheme for realizing efficient and stable PSCs,which incorporates acetamidinium bromide(AABr)as an additive into the MAPbI_(3) lattice,is *** an additive,AABr has been found to provide synergistic multiple passivation for both internal and interfacial *** was found to effectively release the tensile strain of the MAPbI_(3) film by forming a structure stabilized by NH-I hydrogen bonds,as evidenced by calculations based on density functional theory(DFT).Furthermore,the incorporated AABr additives created a charge carrier recombination barrier to enhance charge collection capability by reducing interfacial ***,a power conversion efficiency(PCE)of 20.18%was achieved using a planar device employing AABr-incorporated MAPbI_(3).This was substantially higher than the 18.32% PCE of a pristine MAPbI_(3)-based ***,unencapsulated PSCs using AABr-incorporated MAPbI_(3) absorbers exhibited excellent long-term stability,maintaining>95% of initial PCE up to 1200 hours in ambient air.

关键词： Acetamidinium bromide Planar perovskite solar cell Tensile stress Interface passivation Recombination barrier

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Graphene-GaN Schottky diodes

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Nano Research 2015年第4期8卷 1327-1338页

作者： Seongjun kim Tae Hoon Seo Myung jong kim Keun man song Eun-Kyung Suh Hyunsoo kim School of Semiconductor and Chemical Engineering Semiconductor Physics Research Center Chonbuk National University Jeonju 561-756 Republic of Korea Soft Innovative Materials Research Center Korea Institute of Science and Technology Jeonbuk 561-905 Republic of Korea Korea Advanced Nano Fab Center Suwon 443-700 Republic of Korea

The electrical characteristics of graphene Schottky contacts formed on undoped GaN semiconductors were investigated. Excellent rectifying behavior with a rectification ratio of -10^7 at ±2 V and a low reverse leakage current of 1.0 × 10^-8 A/cm^2 at -5 V were observed. The Schottky barrier heights, as determined by the thermionic emission model Richardson plots, and barrier inhomogeneity model, were 0.90, 0.72, and 1.24 ± 0.13 eV, respectively. Despite the predicted low barrier height of -0.4 eV at the graphene-GaN interface, the formation of excellent rectifying characteristics with much larger barrier heights is attributed to the presence of a large number of surface states （1.2 x 1013 states/cm2/eV） and the internal spontaneous polarization field of GaN, resulted in a significant upward surface band bending or a bare surface barrier height as high as of 2.9 eV. Using the S parameter of 0.48 （measured from the work function dependence of Schottky barrier height） and the mean barrier height of 1.24 eV, the work function of graphene in the Au/graphene/GaN stack could be approximately estimated to be as low as 3.5 eV. The obtained results indicate that graphene is a promising candidate for use as a Schottky rectifier in GaN semiconductors with n-type conductivity.

关键词： graphene GaN Schottky diode Schottky barrier height Fermi level pinning

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Influence of a UV-ozone treatment on amorphous SnO_(2) electron selective layers for highly efficient planar MAPbI3 perovskite solar cells

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Journal of Materials Science & Technology 2020年第24期59卷 195-202页

作者： Kyungeun Jung Du Hyeon kim Jaemin kim Sunglim Ko Jae Won Choi Ki Chul kim Sang-Geul Lee man-jong Lee Department of Advanced Technology Fusion Konkuk UniversitySeoul05029Republic of Korea a Department of Chemistry Konkuk UniversitySeoul05029Republic of Korea Department of Mechanical Design and Production Engineering Konkuk UniversitySeoul05029Republic of Korea Division of Chemical Engineering Konkuk UniversitySeoul05029Republic of Korea Daegu Center Korea Basic Science InstituteDaegu41566Republic of Korea

The effect of ultraviolet-ozone(UVO)irradiation on amorphous(am)SnO_(2) and its impact on the photoconversion efficiency of MAPbI3-based perovskite solar cells were investigated in *** treatment was found to increase the amount of chemisorbed oxygen on the am-SnO_(2) surface,reducing the surface energy and contact *** changes in the am-SnO_(2) surface lowered the Gibbs free energy for the densification of perovskite films and facilitated the formation of homogeneous perovskite *** addition,the Fermi energy of the UVO-treated am-SnO_(2) shifted upwards to achieve an ideal band offset for MAPbI3,which was verified by theoretical calculations based on the density functional *** achieved a champion efficiency of 19.01% with a statistical reproducibility of 17.01±1.34% owing to improved perovskite film densification and enhanced charge transport/extraction,which is considerably higher than the 13.78±2.15% of the ***,UVO-treated,am-SnO_(2)-based devices showed improved stability and less hysteresis,which is encouraging for the future application of up-scaled perovskite solar cells.

关键词： UV-ozone Amorphous SnO_(2) Electron selective layers Planar perovskite solar cells Hysteresis

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Helmet-based noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease: A case report

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World Journal of Clinical Cases 2020年第10期8卷 1939-1943页

作者： Mi Hwa Park Min Jeong kim Ah Jin kim man-jong Lee Jung-Soo kim Division of Pulmonology Department of Internal MedicineInha University HospitalIncheon 22332South Korea Division of Critical Care Medicine Department of Internal MedicineInha University HospitalIncheon 22332South Korea

BACKGROUND Noninvasive ventilation(NIV)reduces intubation rates,mortalities,and lengths of hospital and intensive care unit stays in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Helmet-based NIV is better tolerated than oronasal mask-based ventilation,and thus,allows NIV to be conducted for prolonged periods at higher pressures with minimal air *** SUMMARY A 73-year-old man with a previous diagnosis of COPD stage 4 was admitted to our medical intensive care unit with chief complaints of cough,sputum,and dyspnea of several days’*** 10 mo,he had been on oxygen at home by day and had used an oronasal mask-based NIV at *** intensive care unit admission,he breathed using respiratory accessory *** and signs of infection were detected,and infiltration was observed in the right lower lung field by chest ***,we diagnosed AECOPD by communityacquired *** admission,respiratory distress steadily deteriorated and invasive mechanical ventilation became ***,the patient refused this option,and thus,we selected helmet-based NIV as a salvage *** 3 d of helmet-based NIV,his consciousness level and hypercapnia recovered to his pre-hospitalization *** Helmet-based NIV could be considered as a salvage treatment when AECOPD patients refuse invasive mechanical ventilation and oronasal mask-based NIV is ineffective.

关键词： Acute exacerbation of chronic obstructive pulmonary disease Noninvasive ventilation Helmet Case report

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Robust fault detection of piecewise affine ARX systems

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Journal of Control and Decision 2020年第3期7卷 276-285页

作者： Young-man kim School of Engineering Liberty University1971 University Blvd.LynchburgVAUSA

In this paper,l1 regularisation-based robust fault detection technique for PWARX(PieceWise affine Auto Regressive eXogenous)systems is *** problem is formulated in convex optimisation form using l1 regularisation hence,global solution can be *** regularisation constant plays a key role for finding the number of *** MSE(mean square error)value between actual system and its model under no fault is used as a threshold for tracking dynamics change and detecting *** simplicity of turning only one parameter(regularisation constant)outstands this approach from *** proposed algorithm also shows the capability of separating the dynamics change from additive fault under *** illustration concludes this proposal by demonstrating its effectiveness.

关键词： Piecewise affine ARX fault detection regularisation convex optimisation sparsity

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