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Cardiovascular Innovations and Applications 2023年第1期7卷 44-48页

作者： jong kun park Ilan Vavilin Jacob Zaemes Araba Ofosu-Somuah Raghav Gattani Camila Sahebi Alexander G.Truesdell The University of Texas Health Science Center at Houston HoustonTXUSA MedStar Georgetown University Hospital Washington D.C.USA Inova Heart and Vascular Institute Falls ChurchVAUSA Inova Fairfax Hospital Department of Hematology and Oncology Falls ChurchVAUSA

Background:Spontaneous heparin-induced thrombocytopenia is a pro-thrombotic syndrome in which anti-heparin antibodies develop without heparin *** presentation:A 78-year-old man who underwent a successful lumbar laminectomy presented to the hospital 5 days after discharge for stroke-like symptoms and was found to have acute infarcts of the bilateral frontal *** patient was found to be severely thrombocytopenic and was incidentally found to have an inferior wall myocardial *** investigation led to the diagnosis of bilateral lower extremity deep vein *** overall clinical presentation prompted a detailed hematologic workup that indicated positivity for heparin-induced thrombocy-topenia despite no previous exposure to heparin ***:This case illustrates a patient with no prior lifetime heparin exposure who underwent laminectomy with subsequent development of acute infarcts of the bilateral frontal lobes,an inferior wall myocardial infarction,and bilateral lower extremity deep vein thromboses,with concern for sequelae of spontaneous heparin-induced thrombo-cytopenia.

关键词： Acute coronary syndrome deep vein thrombosis myocardial infarction cerebrovascular infarction spontaneous heparin-induced thrombocytopenia

3D printing-enabled advanced electrode architecture design

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Carbon Energy 2021年第3期3卷 424-439页

作者： Tiankuo Chu Soyeon park kun(Kelvin)Fu Department of Mechanical Engineering University of DelawareNewarkDelawareUSA Center for Composite Materials(CCM) University of DelawareNewarkDelawareUSA

A high-performance energy storage device plays an important role in controlling carbon *** emerging additive manufacturing techniques bring a great revolution of electrode fabrication process and promote the performance of energy storage devices through the advanced electrode architecture *** this paper,recent studies on the three-dimensional(3D)-printed electrode with advanced architecture have been mainly reviewed,including interdigitated structure,through-thickness aligned structure,hierarchical porous structure and fiber and fibric structure of electrodes,and expectations for the development of novel advanced electrode architecture generated and optimized by computational simulation and machine *** strategy of advanced electrode architecture design and fabrication enabled by the 3D printing technique represents a promising direction toward future energy storage devices with high electrochemical and mechanical performance.

关键词： 3D printing additive manufacturing advanced structure battery supercapacitor

Appendectomy in patient with suspected COVID-19 with negative COVID-19 results: A case report

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World Journal of Clinical Cases 2020年第10期8卷 1944-1949页

作者： Changho Kim jong kun Kim In Hwan Yeo Jae Young Choe Jeong Eun Lee So Jeong Kang Chan Sub park Ki Tae Kwon Soyoon Hwang Department of Emergency Medicine School of MedicineKyungpook National UniversityDaegu 41944South Korea Department of Anesthesiology and Pain Medicine School of MedicineKyungpook National UniversityKyungpook National University HospitalDaegu 41944South Korea Department of Surgery School of MedicineKyungpook National UniversityKyungpook National University HospitalDaegu 41944South Korea Department of Internal Medicine School of MedicineKyungpook National UniversityDaeguKoreaDepartment of Infection ControlKyungpook National University Chilgok HospitalDaegu 41944South Korea

BACKGROUND Even at present,we are in the middle of the novel coronavirus disease 2019(COVID-19)pandemic and are facing challenges in trial and ***,emergency surgery for patients with suspected COVID-19 is burdensome not only for patients but also for healthcare ***,we established a surveillance system in the emergency room and established principles for managing patients suspected of COVID-19 who require emergency *** SUMMARY A 67-year-old man was diagnosed with appendicitis in March *** wife was diagnosed with COVID-1910 d earlier,and the patient was in close contact with *** patient tested negative twice on an upper respiratory COVID-19 reverse transcription–polymerase chain reaction screening test,but chest X-ray and chest computed tomography revealed patchy ground-glass opacity in both upper lobes of the patient’s *** same emergency surgery procedure for patients with confirmed COVID-19 was applied to this patient suspected of having the disease to ensure that surgery was not delayed while waiting for the reverse transcription–polymerase chain reaction results.A few hours after surgery,the upper respiratory tract specimen taken in the emergency room was negative for COVID-19 but the lower respiratory tract specimen was found to be positive for the *** When COVID-19 is suspected,emergency surgery should be performed as for confirmed COVID-19 without delay.

关键词： COVID-19 Appendicitis Appendectomy Emergency room Infection control Case report

Rapid assessment checklist for green roof ecosystem services in Bangkok,Thailand

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Ecological Processes 2020年第1期9卷 205-221页

作者： Rattanapan Phoomirat Nipada Ruankaew Disyatat Tae Yoon park Dong kun Lee Pongchai Dumrongrojwatthana Biological Sciences Program Faculty of ScienceChulalongkorn UniversityBangkok 10330Thailand Department of Biology Faculty of ScienceChulalongkorn UniversityBangkok 10330Thailand Graduate School of Education Yonsei UniversitySeoul 03722Republic of Korea Department of Landscape Architecture and Rural System Engineering Seoul National UniversitySeoul 08826Republic of Korea

Background:A green roof is a man-made ecosystem created when a rooftop is covered with substrate and *** green roof ecosystems(GREs)are able to provide ecosystem services,there is currently no assessment tool available to specifically evaluate ***,the aim of this study was to develop a rapid assessment checklist(RAC)to assess GRE services(GRES),which was developed and tested on 10 green roofs in Bangkok,***:The RAC consisted of 46 proxy indicators(33 qualitative and 13 quantitative indicators)encompassing various aspects of *** GRES values or scores varied according to structural differences in the green *** average score(from a maximum of 100)of total ecosystem services was 61±7,which could be inferred as a good performance in ecosystem service *** highest scores were obtained from the regulating services at 68±*** lowest average score was 53±11 from the provisioning ***:The RAC was able to evaluate the levels of GRES provided by the selected green roofs,enabling the meaningful comparison of their potential capability to provide ***,this RAC could be an innovative tool for evaluation of four categories of GRES.

关键词： Vegetated roof Evaluation Composite indicator Urban ecosystem Ecosystem management

Neuromorphic devices based on fluorite-structured ferroelectrics

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InfoMat 2022年第12期4卷 1-32页

作者： Dong Hyun Lee Geun Hyeong park Se Hyun Kim Ju Yong park kun Yang Stefan Slesazeck Thomas Mikolajick Min Hyuk park Department of Materials Science and Engineering&Inter-University Semiconductor Research Center College of EngineeringSeoul National UniversitySeoulRepublic of Korea Research Institute of Advanced Materials Seoul National UniversitySeoulRepublic of Korea NaMLab gGmbH DresdenGermany Institute of Engineering Research Seoul National UniversitySeoulRepublic of Korea

A continuous exponential rise has been observed in the storage and processing of the data that may not curtail in the foreseeable *** required data processing speed and power consumption are restricted by the buses between the logic and memory devices that are characteristic of the von Neumann computing ***-mimicking neuromorphic computing has garnered considerable academic and industrial interest to resolve these ***,devices based on emerging nonvolatile memories capable of mimicking the behaviors of synapses and neurons,which are the main elements in biological computing systems(brains),are attracting significant interest from the device *** the discovery of ferroelectricity in fluorite-structured oxides,such as HfO2 and ZrO2,which are compatible with the state-of-the-art complementary-metal-oxide-semiconductor processes,ferroelectric devices have rapidly evolved as the main direction of these research and development *** science related to fluorite-structured ferroelectrics has been intensively studied over the last *** present,the focus is gradually moving to practical applications,including neuromorphic computing and advanced classical processing or memory units in the conventional von Neumann ***,despite its rapid development,the wealth of recent progress in neuromorphic computing devices based on fluorite-structured ferroelectrics has not been reviewed and *** progress report comprehensively reviews and systemizes the recent progress in artificial synaptic and spiking neuron devices for neuromorphic computing based on fluorite-structured ferroelectrics.

关键词： ferroelectrics hafnia neuromorphic computing semiconductor devices

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美丽园区建设的路径研究

生态经济 2025年第1期41卷 44-51页

作者：陈吕军严坤田金平清华大学环境学院北京100084 清华大学生态文明研究中心北京100084 清华大学碳中和研究院北京100084

建设美丽中国是全面建设社会主义现代化国家、实现中华民族永续发展的重要举措。中国工业园区历经四十多年发展历程,已经成为建设实体经济、引领区域发展的先行者,目前已聚集全国80%的工业企业,推动工业园区建设成为人与自然和谐共生的... 详细信息

建设美丽中国是全面建设社会主义现代化国家、实现中华民族永续发展的重要举措。中国工业园区历经四十多年发展历程,已经成为建设实体经济、引领区域发展的先行者,目前已聚集全国80%的工业企业,推动工业园区建设成为人与自然和谐共生的美丽园区,对我国生态文明建设意义重大。论文回顾了中国工业园区的发展历程,面向新发展阶段存在的新挑战和新机遇,提出了工业园区在新时代需承担的高质量发展使命任务。在此基础上,本文针对园区社会、经济、自然三个子系统,从六个方面解析并详细阐述了中国工业园区打造美丽园区、支撑美丽中国建设的关键内涵。进一步地,根据国家对美丽中国建设提出的目标和计划,结合我国生态工业园区发展过程中形成的实践经验,从八个维度提出工业园区推进美丽中国建设的关键行动,支撑工业园区生态文明建设和美丽中国行动。

关键词：美丽中国工业园区美丽园区绿色发展生态文明

Depolarization mitigated in ferroelectric Hf_(0.5)Zr_(0.5)O_(2)ultrathin films(<5 nm)on Si substrate by interface engineering

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Journal of Advanced Ceramics 2024年第3期13卷 282-292页

作者： Se Hyun Kim Younghwan Lee Dong Hyun Lee Geun Hyeong park Hyun Woo Jeong kun Yang Yong Hyeon Cho Young Yong Kim Min Hyuk park Department of Materials Science and Engineering College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Research Institute of Advanced Materials College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Inter-university Semiconductor Research Center College of EngineeringSeoul National UniversitySeoul 08826Republic of Korea Pohang Accelerator Laboratory Pohang University of Science&TechnologyPohang 790784Republic of Korea

(Hf,Zr)O_(2)offers considerable potential for next-generation semiconductor devices owing to its nonvolatile spontaneous polarization at the ***,scaling this material to sub-5 nm thickness poses several challenges,including the formation of an interfacial layer and high trap *** particular,a low-k SiO_(2)interfacial layer is naturally formed when(Hf,Zr)O_(2)films are directly grown on a Si substrate,leading to high depolarization fields and rapid reduction of the remanent *** address these issues,we conducted a study to significantly improve ferroelectricity and switching endurance of(Hf,Zr)O_(2)films with sub-5 nm thicknesses by inserting a TiO_(2)interfacial *** deposition of a Ti film prior to Hf_(0.5)Zr_(0.5)O_(2)film deposition resulted in a high-k TiO_(2)interfacial layer and prevented the direct contact of Hf_(0.5)Zr_(0.5)O_(2)with *** findings show that the high-k TiO_(2)interfacial layer can reduce the SiO_(2)/Si interface trap density and the depolarization field,resulting in a switchable polarization of 60.2μC/cm^(2)for a 5 nm thick Hf_(0.5)Zr_(0.5)O_(2)***,we propose that inserting a high-k TiO_(2)interfacial layer between the Hf_(0.5)Zr_(0.5)O_(2)film and the Si substrate may offer a promising solution to enhancing the ferroelectricity and reliability of(Hf,Zr)O_(2)grown on the Si substrate and can pave the way for next-generation semiconductor devices with improved performance.

关键词： ferroelectric charge trapping hafnia depolarization

Antioxidant effect of Lactobacillus fermentum HFY02-fermented soy milk on D-galactose-induced aging mouse model

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Food Science and Human Wellness 2022年第5期11卷 1362-1372页

作者： Tiantian Hu Rui Chen Yu Qian Ke Ye Xingyao Long kun-Young park Xin Zhao Chongqing Collaborative Innovation Center for Functional Food Chongqing Engineering Research Center of Functional FoodChongqing Engineering Laboratory for Research and Development of Functional FoodChongqing University of EducationChongqing 400067China Department of General Practice The Third People's Hospital of ChengduChengdu 610036China Department of Food Science and Biotechnology Cha UniversitySeongnam 13488Korea

This study aimed to investigate the antioxidant effect of soybean milk fermented by a new type of Lactobacillus fermentum(LF-HFY02)by using D-galactose induced aging mice ***,the optimal fermentation conditions was screened out by detecting the effects of different fermentation temperature and time on the active components and antioxidant activity of soybean milk in *** then unfermented soybean milk and the soybean milk fermented by different Lactobacillus was given by gavage to D-galactose-induced aging *** activities of GSH,GSH-Px,SOD,CAT and T-AOC in serum,brain and liver of soybean milk fermented by LF-HFY02 were significantly increased,while the content of MDA and the level of AGEs in hippocampal were significantly decreased compared with D-galactose induced *** more,the mRNA expression of GSH and SOD in mouse liver were obviously up-regulated by soybean milk fermented by *** skin tissue structure of mice in the LF-HFY02 fermented soybean milk group was more complete,the collagen fibers were increased and arranged orderly and liver inflammation has improved compared with the model *** Western blot analysis showed that LF-HFY02 effectively upregulated EGFR,SOD and GSH protein expression in mouse *** findings suggest that LF-HFY02 can effectively prevent D-galactose-induced oxidation and aging in mice,and the effect was even better than that of the Lactobacillus delbruechii *** and vitamin ***,LF-HFY02 may be potentially employed as a probiotic *** conclusion,soybean milk fermented by LF-HFY02 can increase the content of antioxidant factors and the activity of antioxidant enzymes by regulating gene and protein expression,and finally inhibit the process of tissue cell peroxidation,and improve the oxidative damage of mouse skin and *** results could provide a basis for the research and development and industrial production of probiotic-related fermented soybean milk products.

关键词： Lactobacillus fermentum HFY02 Fermented soybean milk D-galactose Antioxidant Aging

TROPICAL CYCLOGENESIS DETECTION IN NWP AT KMA

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Tropical Cyclone Research and Review 2014年第4期3卷 256-269页

作者： Woojeong Lee KiRyong Kang Jiyoung Kim kun-Young Byun jong Sook park Seonghee Won Yunho park WonTae Yun National Typhoon Center Korea Meteorological AdministrationJejuKorea Weather Radar Center Korea Meteorological AdministrationSeoulKorea Global Environment System Research Division National Institute Meteorological ResearchKorea Meteorological AdministrationJejuKorea Foreast Research Division National Institute Meteorological ResearchKorea Meteorological AdministrationJejuKorea Numerical Model Development Division Korea Meteorological AdministrationSeoulKorea

In this study,a tropical cyclogenesis detection system,Tropical Cyclone Analysis&Forecast(TCAF),was evaluated with an operational numerical model of the Korea Meteorological Administration(KMA).The tracking performance was compared with the result with the ECMWF model input field(TCAF-ECMWF).In order to improve the performance,different tracking time at an interval of 6 hours were *** lowest false alarm rate and the highest hit rate(correct detection)were achieved at 06 hour after the initial tracking *** tracking performance was also tested on two typhoons in 2013,LEEPI(1304)and DANAS(1324).The results showed that the TCAF-ECMWF detected tropical depressions 72 hours before the formation of the typhoon DANAS,which is a 12-hour earlier detection compared with the current performance with the use of KMA’s numerical weather prediction(NWP)model ***,it is expected that TC genesis detection could be improved by determining an optimal tracking time and by using more accurate NWP model data.

关键词： tropical cyclone genesis detection numerical weather prediction

Treatment for gastric ‘indefinite for neoplasm/dysplasia' lesions based on predictive factors

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World Journal of Gastroenterology 2019年第4期25卷 469-484页

作者： Mi Jung Kwon Ho Suk Kang Hyeon Tae Kim Jin Woo Choo Bo Hyun Lee Sung Eun Hong kun Ha park Dong Min Jung Hyun Lim Jae Seung Soh Sung Hoon Moon jong Hyeok Kim Hye-Rim park Soo Kee Min Jin won Seo Ji-Young Choe Department of Pathology Hallym University Sacred Heart Hospital Hallym University College of Medicine Department of Internal Medicine Hallym University Sacred Heart Hospital

BACKGROUND Gastric ‘indefinite for neoplasm/dysplasia'(IFND) is a borderline lesion that is difficult to diagnose as either regenerative or neoplastic. There is a need for guidance in the identification of a subset of patients, who have an IFND lesion with a higher risk of malignant potential, to enable risk stratification and optimal *** To determine the clinical and pathologic factors for the accurate diagnosis of gastric IFND *** In total, 461 gastric lesions diagnosed via biopsy as IFND lesions were retrospectively evaluated. Endoscopic resection(n = 134), surgery(n = 22), and follow-up endoscopic biopsy(n = 305) were performed to confirm the *** time interval from initial biopsy to cancer diagnosis was measured, and diagnostic delays were categorized as > 2 wk, > 2 mo, > 6 mo, and > 1 year. The IFND lesions presenting as regenerating atypia(60%) or atypical epithelia(40%)at initial biopsy were adenocarcinomas in 22.6%, adenomas in 8.9%, and gastritis in 68.5% of the *** Four clinical factors [age ≥ 60 years(2.445, 95%CI: 1.305-4.580, P = 0.005),endoscopic size ≥ 10 mm(3.519, 95%CI: 1.891-6.548, P < 0.001), single lesion(5.702, 95%CI: 2.212-14.696, P < 0.001), and spontaneous bleeding(4.056, 95%CI:1.792-9.180, P = 0.001)], and two pathologic factors [atypical epithelium(25.575,95%CI: 11.537-56.695, P < 0.001], and repeated IFND diagnosis [6.022, 95%CI:1.822-19.909, P = 0.003)] were independent risk factors for gastric cancer. With two or more clinical factors, the sensitivity and specificity for carcinoma were91.3% and 54.9%, respectively. Ten undifferentiated carcinomas were initially diagnosed as IFND. In the subgroup analysis, fold change(5.594, 95%CI: 1.458-21.462, P = 0.012) predicted undifferentiated or invasive carcinoma in the submucosal layers or deeper. Diagnostic delays shorter than 1 year were not associated with worse prognoses. Extremely well-differentiated adenocarcinomas accounted for half of the repeate

关键词： Gastric cancer Biopsy Endoscopic surgical procedure Diagnostic delay Prognosis