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A critical review:emerging bioeconomy and waste-to-energy technologies for sustainable municipal solid waste management

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waste Disposal and Sustainable Energy 2019年第3期1卷 151-167页

作者： To-Hung Tsui jonathan w.c.wong Department of Biology Institute of Bioresource and AgricultureSino-Forest Applied Research Centre for Pearl River Delta EnvironmentHong Kong Baptist UniversityKowloon TongHong KongChina

Municipal solid waste(MSw)management has emerged as probably the most pressing issue many governments nowadays are ***,waste-to-Energy(wtE)is mostly associated with incineration,but now,with the emergence of the bioeconomy,it embraces a broader definition comprising any processing technique that can generate electricity/heat or produce a waste-derived *** the ambit of the circular economy many nations are looking for,additional effort must be made to be sure of acquiring the most updated information and paving a sustainable path for managing MSw in such a *** this regard,we have undertaken a critical review of various technologies,with their updated progress,involved in the exploitation of MSw as a renewable resource,along with the critical advantages and limitations on energy and material cycling for sustainable MSw ***,the most widely used method,is nowadays difficult to further apply due to its dubious reputation and social ***,to address the organic fraction of MSw which currently is mostly unrecycled and causes disposal issues,the biological approach presents an attractive *** new emphasis of bioeconomy leads us to understand how environmental biotechnologies should be better connected/integrated for more sustainable MSw *** article is concluded with advances of future prospects,which can serve as a timely reminder to encourage competent authorities/researchers to work towards further improvement of the present MSw management system.

关键词： Municipal solid waste management Sustainability circular economy Bioeconomy waste-to-energy Anaerobic digestion

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施用污泥堆肥对作物和土壤的影响

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土壤与环境 2000年第4期9卷 277-280页

作者：张桥吴启堂黄焕忠廖新弟周立祥华南农业大学资源环境学院广东广州510642 香港浸会大学生物系华南农业大学动物科学系广东广州510642 南京农业大学资源与环境学院江苏南京210095

污泥中的有机质、营养成分可为农业生产提供重要的有机肥源，但污泥中的重金属是制约污泥农用的重要因素，为检验污泥堆肥施用后对作物及土壤的影响，文章对污泥与稻草或木屑堆肥的产品进行了盆栽试验研究。结果表明，污泥与稻草或木屑... 详细信息

污泥中的有机质、营养成分可为农业生产提供重要的有机肥源，但污泥中的重金属是制约污泥农用的重要因素，为检验污泥堆肥施用后对作物及土壤的影响，文章对污泥与稻草或木屑堆肥的产品进行了盆栽试验研究。结果表明，污泥与稻草或木屑的堆肥作为肥料施用于萝卜（Brassica campestris）和菜心（Brassica parachinensis），产量明显提高，部分堆肥产品增产效果优于化肥，且后效明显。堆肥施用使土壤中有机质、各养分含量增加，微生物活动增强、数量增加，然而作物和土壤中的重金属含量也有不同程度的提高。

关键词：污泥堆肥作物影响施肥土壤

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A spotlight on dosage and subject selection for effective neuroprotection: exploring the central role of mitochondria

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Neural Regeneration Research 2025年第4期20卷 1081-1082页

作者： John Mitrofanis jonathan Stone Michael R.Hamblin Pierre Magistretti Alim-Louis Benabid Glen Jeffery Fonds clinatec UniversitéGrenoble AlpesGrenobleFrance School of Medical Science University of SydneySydneyAustralia Faculty of Health Sciences University of JohannesburgJohannesburgSouth Africa King Abdullah University of Science and Technology ThuwalSaudi Arabia Institute of Ophthalmology University College LondonLondonUK

Neurons are notoriously vulnerable cell *** the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological conditions,including stroke,head trauma,and neurodegenerative disease,can generate stress in neurons,affecting their survival and proper *** most neural pathologies,mitochondria become dysfunctional and this plays a pivotal role in the process of cell *** challenge over the last few decades has been to develop effective interventions that improve neuronal homeostasis under pathological *** interventions,often referred to as disease-modifying or neuroprotective,have,however,proved frustratingly elusive,at both preclinical and,in particular,clinical *** this perspective,we highlight two factors that we feel are key to the development of effective neuroprotective *** are:firstly,the choice of dose of intervention and method of application,and secondly,the selection of subjects,whether they be patients or the animal model.

关键词： protective dosage distress

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wilson's disease in two siblings from Ecuador:Two case reports

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world Journal of clinical cases 2025年第3期13卷 50-60页

作者： Enrique carrera jonathan Alvarado Martina Astudillo Galo Pillajo Department of Gastroenterology and Hepatology Hospital de Especialidades Eugenio EspejoQuito 170136PichinchaEcuador Faculty of Medicine Pontificia Universidad Catolica del EcuadorQuito 170143PichinchaEcuador Department of Radiology Hospital de Especialidades Eugenio EspejoQuito 170136PichinchaEcuador

BAcKGROUND wilson's disease(wD)is a rare metabolic disorder of copper accumulation in organs such as liver,brain,and *** and treatments are challenging in settings,where advanced diagnostic tests are unavailable,copper chelating agents are frequently scarce,healthcare professionals lack disease awareness,and medical follow-ups are *** diagnoses and treatments help prevent complications,improve patients’quality of life,and ensure a normal life *** clinical presentations and outcomes of wD can vary within a single *** SUMMARY we present the cases of two siblings(19 and 27 years)from a consanguineous family in rural Ecuador,diagnosed as having wD during a family *** male patient,diagnosed at age 19 after his brother’s death from acute liver failure,presented with compensated cirrhosis,neurological symptoms,and bilateral Kayser-Fleischer *** developed progressive neurological deterioration during an irregular treatment with D-penicillamine due to medication *** condition improved upon switching to trientine tetrahydrochloride,and his neurological symptoms improved over an 8-year period of *** female patient,diagnosed at age 10,exhibited only biochemical *** treatment history was similar;however,she remained asymptomatic without disease progression over the same follow-up *** discuss the potential influence of epigenetic mechanisms and modifier genes on the various phenotypes,emphasizing the need for research in these areas to optimize therapeutic *** Our patients’medical histories show how early diagnosis and treatment can prevent disease progression;and,how suboptimal treatments impact disease outcomes.

关键词： wilson disease Kayser-Fleischer rings copper chelator D-penicillamine Trientine tetrahydrochloride case report

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AccELERATED OPTIMIZATION wITH ORTHOGONALITY cONSTRAINTS

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Journal of computational Mathematics 2021年第2期39卷 207-226页

作者： jonathan w.Siegel Department of Mathematics Pennsylvania State UniversityUniversity ParkPAUSA

we develop a generalization of Nesterov’s accelerated gradient descent method which is designed to deal with orthogonality *** demonstrate the effectiveness of our method,we perform numerical experiments which demonstrate that the number of iterations scales with the square root of the condition number,and also compare with existing state-of-the-art quasi-Newton methods on the Stiefel *** experiments show that our method outperforms existing state-of-the-art quasi-Newton methods on some large,ill-conditioned problems.

关键词： Riemannian optimization Stiefel manifold Accelerated gradient descent Eigenvector problems Electronic structure calculations

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complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts christian Mustroph David Gimbel jonathan Grossberg Daniel L.Barrow Matthew F.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

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Altaids: accretionary tectonics writ large

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National Science Review 2023年第2期10卷 12-13页

作者： jonathan c.Aitchison School of Earth and Environmental Sciences The University of Queensland

This perspective is written through the lens of someone who,except for a limited but enlightening foray into the region25 years ago,has largely watched the evolution of thinking and understanding of the Altaids from *** area is a hotbed for new ideas and *** strongly held viewpoints associated with various schools of thought have been *** time,international collaboration has moved thinking towards a consensus view,which hopefully will not stifle valuable originality.

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Flu DRiPs in MHc class Ⅰ Immunosurveillance

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Virologica Sinica 2019年第2期34卷 162-167页

作者： Jiajie wei jonathan w.Yewdell cellular Biology Section Laboratory of Viral DiseasesNational Institute of Allergy and Infectious DiseasesNational Institutes of Health

Since the publication of the DRiP(defective ribosomal product) hypothesis in 1996, numerous studies have addressed the contribution of DRiPs to generating viral antigenic peptides for cD8^+T cell immunosurveillance. Here, we review studies characterizing the generation of antigenic peptides from influenza A virus encoded DRiPs, discuss the many remaining mysteries regarding the nature of their co-translational generation, and speculate on where the future might lead.

关键词： Influenza A virus(IAV) MHc-restricted cytotoxicity Immune responses MHc class Ⅰ DRiP

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Global distribution of geothermal gradients in sedimentary basins

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Geoscience Frontiers 2023年第6期14卷 478-495页

作者： Folarin Kolawole jonathan c.Evenick Lamont-Doherty Earth Observatory at columbia University New YorkNYUSA INPEX corporation TokyoJapan

The heat budget of sedimentary basins is determined by heat transfer across the lithosphereasthenosphere boundary and lithospheric heat sources,such that the tectonic evolution of their host continental and oceanic lithosphere ultimately impact the present-day heat flow and average geothermal *** increase in availability of publicly-accessible geothermal gradient measurements across the world provides an opportunity to globally assess the dominant controls on the thermal regime of sedimentary ***,we compile a global dataset of152,000 unique data points with constrained bottomhole temperature measurements and assess the relationships between geothermal gradient and selected independent tectonic variables,including crustal and lithospheric thicknesses,crustal age,sediment thickness,and basin *** results show that in both oceanic and continental settings,geothermal gradients exhibit a non-linear,systematic variation with the tectonic *** find that oceanic geothermal gradients decrease with increasing crustal age and lithospheric *** gradients in the continents show no clear relationships with thermotectonic crustal age,but decrease with increasing crustal and lithospheric *** drop significantly at 1.5 km sediment-cover thickness,likely reflecting the effect of high sedimentation rates,but show a striking rise at>12 km thicknesses,potentially influenced by thinned lithosphere and thermal blanketing *** commonly-assumed‘normal’gradient of 25℃/km for continents is only valid for a narrow range(1.5–12.5 km)of sedimentary cover-thickness,and oceanic‘normal’gradient may be as high as 50–75℃/km for>20 Ma crustal age and>50 km-thick *** show that,conditionally,crustal age may best predict average geothermal gradients in oceanic settings,and lithosphere thickness in ***,we observe that tectonic basin types exhibit distinct ranges of gradients that reflect their prevalent tec

关键词： Geothermal gradient Oceanic crust continental crust Lithosphere Tectonics

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A Numerical Study of Temporal Mixing Layer with Three-Dimensional Mortar Spectral Element Method

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chinese Physics Letters 2011年第6期28卷 187-189页

作者： ZHANG Xu LIU Jin-Hong jonathan w.N Institute of Fluid Physics China Academy of Engineering PhysicsMianyang 621900 Mechanical Department University of WyomingLaramieUSA

we investigate a set of well-posed interface conditions of viscous fluxes of Navier–Stokes equations,extend them to three-dimensional Navier–Stokes equations and successfully study a temporally turbulent mixing *** evolution of a large vortex structure and the non-dimensional statistical quantities in the mixing layer are numerically *** span-wise energy spectrum of the mixing layer exhibits wide band features,which means that the simulation generates the desired amount of small *** results show that too many small scales are present due to insufficient dissipation and the amount of large scales is low,indicating too much dissipation for large-scale structures.

关键词： layer mixing dissipation

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