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r.diofr.quency induced heat.ng of biodegr.dable or.hopaedic scr.w implant. dur.ng magnet.c r.sonance imaging

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Bioact.ve Mat.r.als 2023年第7期25卷 86-94页

作者： jonathan Espir.t. Most.fa Ber.ngi Hanna Cwieka Kamila Iskhakova Andr. Kuehne D.C.Flor.an Wieland Ber.t.Zeller.Plumhoff t.or.lf Niendor. r.gine Willumeit.r.mer.Jan-Mar.en Seit. Synt.llix AG HannoverGermany Mr..t.OLS GmbH BerlinGermany Char.t.-Univer.it.t.medizin Ber.in Corporate Member of Freie Universität Berlin and Humboldt Universität zu BerlinBerlinGermany Ber.in Ult.0}high Field Facilit.(B.U.F.F.) Max-Delbrueck Center for Molecular Medicine in the Helmholtz AssociationBerlinGermany Inst.t.t. of Met.llic Biomat.r.als Helmholtz Zentrum HereonGeesthachtGermany

Magnesium(Mg)-based implant. have r.-emer.ed in or.hopaedic sur.er. as an alt.r.at.ve t. per.anent.*** r.veals lit.le infor.at.on on how t.e degr.dat.on of biodegr.dable implant. may int.0}duce safet. implicat.ons for.pat.ent.follow-up using medical *** r.sonance imaging(Mr.)benefit. post.sur.er. monit.r.ng of bone healing and implant.t.on *** st.dies demonst.0}t.d r.diofr.quency(r.)heat.ng of per.anent.implant. caused by elect.0}magnet.c fields used in *** invest.gat.on is t.e fir.t.t. r.por. t.e effect.of t.e degr.dat.on layer.on r.-induced heat.ng of biodegr.dable or.hopaedic ***43 or.hopaedic compr.ssion scr.ws under.ent.in vit.0} *** t.chniques wer. applied t. assess t.e cor.osion pr.cess and t.e mat.r.al composit.on of t.e degr.ded *** measur.ment. wer. per.or.ed t. quant.fy implant.heat.ng wit. r.spect.t. t.e degr.dat.on *** compar.son,a commer.ial t.t.nium implant.scr.w was *** r. induced heat.ng was obser.ed for.non-degr.ded WE43 scr.w *** heat.ng had shown t. decr.ase wit. t.e for.at.on of t.e degr.dat.on *** st.t.st.cal differ.nces wer. obser.ed for.heat.ng of t.e non-degr.ded WE43 mat.r.al and t.e t.t.nium *** highest.r.sk of implant.r. heat.ng is most.pr.nounced for.Mg-based scr.ws pr.or.t. *** t. indust.0} st.ndar.s for.Mr. safet. assessment.is war.ant.d t. include biodegr.dable mat.r.als.

关键词： Biodegr.dable implant. Magnesium Medical imaging Magnet.c r.sonance imaging Pat.ent.safet.

r.sk assessment.of venous t.r.mboembolism in inflammat.r. bowel disease by inher.t.d r.sk in a populat.on-based incident.cohor.

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Wor.d Jour.al of Gast.0}ent.r.logy 2023年第39期29卷 5494-5502页

作者： Andr.w S r.fkin Zhuqing Shi Jun Wei Siqun Lilly Zheng Br.an t.Helfand jonathan S Cor.ova Vincent.F Biank Alfonso J t.fur.Omar.Khan Jianfeng Xu Pr.gr.m for.Per.onalized Cancer.Car. NorthShore University HealthSystemEvanstonIL 60201United States Depar.ment.of Sur.er. NorthShore University HealthSystemEvanstonIL 60201United States Pr.t.ker.School of Medicine University of ChicagoChicagoIL 60637United States Depar.ment.of Pediat.0}cs NorthShore University HealthSystemEvanstonIL 60201United States Car.iovascular.Inst.t.t. NorthShore University HealthSystemEvanstonIL 60201United States Depar.ment.of Medicine NorthShore University HealthSystemEvanstonIL 60201United States

Inflammat.r. bowel disease(IBD),including Cr.hn’s disease(CD)and ulcer.t.ve colit.s(UC),is a chr.nic inflammat.r. disease of t.e digest.ve t.0}ct.wit. incr.asing pr.valence *** venous t.r.mboembolism(Vt.)is a major.complicat.on in IBD pat.ent.,it.is oft.n under.ppr.ciat.d wit. limit.d t.ols for.r.sk *** t. est.mat. t.e pr.por.ion of Vt. among IBD pat.ent. and assess genet.c r.sk fact.r.(monogenic and polygenic)for.*** Incident.Vt. was followed for.8465 IBD pat.ent. in t.e UK Biobank(UKB).t.e associat.ons of Vt. wit. F5 fact.r.V leiden(FVL)mut.t.on,F2 G20210A pr.t.r.mbin gene mut.t.on(PGM),and polygenic scor.(PGS003332)wer. t.st.d using Cox hazar.s r.gr.ssion analysis,adjust.ng for.age at.IBD diagnosis,gender.and genet.c backgr.und(t.p 10 pr.ncipal component.).t.e per.or.ance of genet.c r.sk fact.r. for.discr.minat.ng Vt. diagnosis was est.mat.d using t.e ar.a under.t.e r.ceiver.oper.t.ng char.ct.r.st.c cur.e(AUC).r.SULt. t.e over.ll pr.por.ion of incident.Vt. was 4.70%in IBD pat.ent. and was similar.for.CD(4.46%),UC(4.49%),and unclassified(6.42%),and compar.ble t. t.at.of cancer.pat.ent.(4.66%)who ar. well-known at.incr.ased r.sk for.*** car.ier. of F5/F2 had a significant.y incr.ased r.sk for.Vt. compar.d t. non-mut.t.on car.ier.,hazar. r.t.o(Hr.was 1.94,95%confidence int.r.al(CI):*** cont.0}st.pat.ent. wit. t.e t.p PGS decile had a consider.bly higher.r.sk for.Vt. compar.d t. t.ose wit. int.r.ediat. scor.s(middle 8 deciles),Hr.was 2.06(95%CI:1.57-2.71).t.e AUC for.differ.nt.at.ng Vt. diagnosis was 0.64(95%CI:0.61-0.67),0.68(95%CI:0.66-0.71),and 0.69(95%CI:0.66-0.71),r.spect.vely,for.F5/F2 mut.t.on car.ier.,PGS,and *** Similar.t. cancer.pat.ent.,Vt. complicat.ons ar. common in IBD *** pr.vides mor. infor.at.ve r.sk infor.at.on t.an F5/F2 mut.t.ons(FVL and PGM)for.per.onalized t.r.mbopr.phylaxis.

关键词： Inflammat.r. bowel disease Venous t.r.mboembolism Polygenic scor. Fact.r.V leiden Pr.t.r.mbin gene mut.t.on

A syst.mat.c r.view of pr.-hospit.l shoulder.r.duct.on t.chniques for.ant.r.or.shoulder.dislocat.on and t.e effect.on pat.ent.r.t.r. t. funct.on

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Chinese Jour.al of t.0}umat.logy 2020年第5期23卷 295-301页

作者： Joseph t.Fennelly Lysander.Gour.ault.Gr.gor. Neal-Smit. Akhilesh Pr.dhan Venkat.Gade jonathan A.Baxt.r t.0}uma and Or.hopaedics Stoke Mandeville HospitalAylesburyHP218ALUK t.0}uma and Or.hopaedics Royal United HospitalBathBA13NGUK

Pur.ose:t.e major.t. of acut. ant.r.or.shoulder.dislocat.ons ar. sust.ined dur.ng spor.s and wilder.ess *** management.of acut. dislocat.ons in t.e pr.-hospit.l set.ing is cur.ent.y wit.out.guidelines based on t.e *** st.dy aims t. assess t.e r.sk of acut. complicat.ons in pr.-hospit.l shoulder.r.duct.on and ident.fy which pr.-hospit.l r.duct.on t.chnique has t.e highest.success r.t. in t.e published ***:t.e involved dat.bases wer. Allied and Complement.r. Medicine,CENt.0}L,CINAHL,Cochr.ne Dat.base of Syst.mat.c r.views,Embase,Eur.pe PMC,Ovid MEDLINE®,Pedr.,Pr.quest.t.0}p,and Wor.d Healt. Or.anizat.on Int.r.at.onal Clinical t.0}als r.gist.0} *** or.ginal r.sear.h of high met.odological qualit. was included,which was defined by t.e r.cent.y developed assessment.t.oleassessing t.e met.odological qualit. of published paper.(AMQPP)and invest.gat.d t.e management.of acut. ant.r.or.shoulder.dislocat.ons in t.e pr.-hospit.l ***:t.o hundr.d and ninet.-eight.ar.icles wer. ident.fied and scr.ened.A full t.xt.r.view was per.or.ed on 40 *** ar.icles published bet.een 2015 and 2018 met.t.e inclusion cr.t.r.a.A t.t.l of 181 pat.ent. wer. included wit. t.e st.dy dur.t.on r.nging fr.m 6 t. 60 *** st.dies r.por.ed zer. immediat. complicat.on following pr.-hospit.l r.duct.on and t.er. wer. no document.d subsequent.adver.e event. r.gar.less of t.e t.chnique *** r.solut.on of neur.logical sympt.ms was obser.ed following t.e ear.y and successful pr.-hospit.l *** at.empt.success r.t.,when per.or.ed by skilled pr.ct.t.oner.,r.nged fr.m 72.3%t. 94.9%.Conclusion:Pr.-hospit.l shoulder.r.duct.on appear. t. be a safe and feasible opt.on when car.ied out.wit. t.e appr.pr.at. exper.ise.A novel r.duct.on t.chnique adapt.d fr.m t.e mount.in medicine diploma cour.e at.t.e Univer.it. of Par.s Nor.h was found t. have t.e highest.fir.t.at.empt.r.duct.on success r.t. of 94.9%.Ot.er.t.chniques descr.bed in t.e lit.

关键词： Should dislocat.on Pr.-hospit.l r.duct.on Success r.t. Imaging

Advanced biomedical hydr.gels:molecular.ar.hit.ct.r. and it. impact.on medical applicat.ons

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r.gener.t.ve Biomat.r.als 2021年第6期8卷 297-317页

作者： jonathan t.Pet.r. Mar.ssa E.Wechsler.Nicholas A.Peppas McKet.a Depar.ment.of Chemical Engineer.ng The University of Texas at AustinAustin200 E.Dean KeetonAustinTX 78712USA Inst.t.t. for.Biomat.r.als Drug Deliveryand Regenerative MedicineThe University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA Depar.ment.of Biomedical Engineer.ng and Chemical Engineer.ng The University of Texas at San AntonioOne UTSA CircleSan AntonioTX78249USA Depar.ment.of Biomedical Engineer.ng The University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA Division of Molecular.Phar.aceut.cs and Dr.g Deliver. College of PharmacyThe University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA Depar.ment.of Sur.er. and Per.oper.t.ve Car. and Department of PediatricsDell Medical SchoolThe University of Texas at Austin1601 Trinity St.Bldg.BAustinTX 78712USA

Hydr.gels ar. cr.ss-linked polymer.c net.or.s swollen in wat.r.physiological aqueous solut.ons or.biological *** ar. synt.esized by a wide r.nge of polymer.zat.on met.ods t.at.allow for.t.e int.0}duct.on of linear.and br.nched unit. wit. specific molecular.*** addit.on,t.ey can be t.ned t. exhibit.desir.ble chemical char.ct.r.st.cs including hydr.philicit. or.*** synt.esized hydr.gels can be anionic,cat.onic,or.amphiphilic and can cont.in mult.funct.onal cr.sslinks,junct.ons or.t.e *** t.ese char.ct.r.st.cs,hydr.gels exhibit.compat.bilit. wit. biological syst.ms,and can be synt.esized t. r.nder.syst.ms t.at.swell or.collapse in r.sponse t. ext.r.al *** ver.at.lit. and compat.bilit. have led t. bet.er.under.t.nding of how t.e hydr.gel’s molecular.ar.hit.ct.r. will affect.t.eir.physicochemical,mechanical and biological *** pr.sent.a cr.t.cal summar. of t.e main met.ods t. synt.esize hydr.gels,which define t.eir.ar.hit.ct.r.,and advanced st.0}ct.r.l char.ct.r.st.cs for.macr.molecular.biological applicat.ons.

关键词： hydr.gels net.or.s mesh size hydr.gel r.act.ons biological applicat.ons biomedical applicat.ons

St.0}t.gies t. t.ckle t.e challenges of ext.r.al beam r.diot.er.py for.liver.t.mor.

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Wor.d Jour.al of Hepat.logy 2017年第14期9卷 645-656页

作者： Michael I Lock jonathan Klein Hans t.Chung Joseph M Her.an Edwar. Y Kim William Small Nina A Mayr.Simon S Lo Depar.ment.of r.diat.on Oncology London Regional Cancer ProgramUniversity of Western Ontario Depar.ment.of r.diat.on Oncology Odette Cancer CentreSunnybrook Health Sciences Centre Depar.ment.of r.diat.on Oncology the University of Texas Depar.ment.of r.diat.on Oncology University of Washington School of Medicine Depar.ment.of r.diat.on Oncology Loyola University Medical Center

Pr.mar. and met.st.t.c liver.cancer.is an incr.asingly common and difficult.t. cont.0}l disease *** offer. a non-invasive t.0}at.ent.alt.r.at.ve for.t.ese pat.ent. who oft.n have few opt.ons and a poor.***,t.e anat.my and aggr.ssiveness of liver.cancer.poses significant.challenges such as accur.t. localizat.on at.simulat.on and t.0}at.ent.management.of mot.on and appr.pr.at. select.on of dose *** ar.icle aims t. r.view t.e opt.ons available and pr.vide infor.at.on for.t.e pr.ct.cal implement.t.on and/or.impr.vement.of liver.cancer.r.diat.on pr.gr.ms wit.in t.e cont.xt.of st.r.ot.ct.c body r.diot.er.py and image-guided r.diot.er.py *** pat.ent.inclusion and exclusion cr.t.r.a ar. pr.sent.d given t.e significant.t.xicit. found in cer.ain sub-populat.ons t.0}at.d wit. ***,cer.ain sub-populat.ons,such as t.ose wit. t.mor.t.r.mbosis or.t.ose wit. lar.er.lesions t.0}at.d wit. t.0}nsar.er.al chemoembolizat.on,have been shown t. have significant.impr.vement. in out.ome wit. t.e addit.on of r.diat.on and mer.t.special *** a liver.r.diat.on pr.gr.mr.quir.s t.r.e pr.mar. challenges t. be addr.ssed:(1) immobilizat.on and mot.on management.(2) localizat.on;and(3) dose r.gimen and const.0}int.*** t. deal wit. mot.on include simple int.r.al t.r.et.volume(It.) expansions,non-gat.d It. r.duct.on st.0}t.gies,br.at. hold met.ods,and sur.ogat. mar.er.met.ods t. enable gat.ng or.*** of t.e t.mor.and or.ans-at.r.sk ar. addr.ssed using cont.0}st.infusion t.chniques t. t.ke advant.ge of differ.nt.nor.al liver.and cancer.vascular.anat.my,imaging modalit.es,and mar.in ***,a dose r.sponse has been demonst.0}t.d and dose r.gimens appear.t. be conver.ing.A mor. unifor. appr.ach t. t.0}at.ent.in t.r.s of t.chnique,dose select.on and pat.ent.select.on will allow us t. st.dy liver.r.diat.on in lar.er.and,hopefully,mult.cent.r.r.ndomized st.dies.

关键词： Hepat.cellular.car.inoma Liver.met.st.ses 4DCt Image-guided r.diot.er.py St.r.ot.ct.c body r.diat.on t.er.py

DNA met.ylat.on pat.er.s in alcoholics and family cont.0}ls

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Wor.d Jour.al of Gast.0}int.st.nal Oncology 2012年第6期4卷 138-144页

作者： Manish t.apar.jonathan Covault.Vict.r.Hesselbr.ck Her.er. L Bonkovsky Depar.ment.of Medicine The University of Connecticut Health Center Farmington CT 06030 United States t.e Liver.Biliar.-Pancr.at.c Cent.r The University of Connecticut Health Center Farmington CT 06030 United States Depar.ment.of Psychiat.0} The University of Connecticut Health Center Farmington CT 06030 United States t.e Alcohol r.sear.h Cent.r The University of Connecticut Health Center Farmington CT 06030 United States t.e Liver.Biliar.-Pancr.at.c Cent.r Carolinas Medical Center Suite 201 Cannon Research Center 1542 Garden Terrace Charlotte NC 28203 United States

AIM: t. assess whet.er.DNA met.ylat.on pat.er.s in chr.nic alcoholics ar. differ.nt.fr.m non-alcoholic sibling cont.0}ls. MEt.ODS: We examined t.e met.ylat.on pat.er.s in DNA samples fr.m 25 chr.nic alcoholics and 22 mat.hed siblings as cont.0}ls (one per.family). DNA was ext.0}ct.d fr.m per.pher.l blood and analyzed for.differ.nces in t.e met.ylat.on pat.er.s aft.r.bisulfit.-conver.ion. We used t.e Illumina GoldenGat. Met.ylat.on Cancer.Panel I (Illumina, San Diego, CA), which pr.bes t.e met.ylat.on pr.file at.1505 CpG sit.s fr.m 807 cancer.r.lat.d genes. We excluded t.e 84 X-chr.mosome CpG sit.s and 134 aut.somal CpG sit.s t.at.failed t. show a wit.in sample r.liabilit. scor. of at.least.95% for.all samples, leaving 1287 aut.somal CpG sit.s (associat.d wit. 743 aut.somal genes) wit. r.liable signals for.all samples. A met.ylat.on scor. was calculat.d as t.e aver.ge met.ylat.on for.t.e 1287 CpG sit.s examined. Differ.nces wer. assessed by a t.o-sample t.t.st. We also examined t.e aver.ge sib pair.differ.nces in met.ylat.on scor.s at.each of t.e 1287 sit.s. All analyses wer. per.or.ed using SPSS, ver.ion 9.0, P r.d significant. r.SULt.: Met.ylat.on levels at.t.e 1287 CpG sit.s aver.ged 28.2% for.bot. alcoholics and cont.0}ls. t.e mean differ.nce in met.ylat.on scor.s bet.een alcoholic and non-alcoholic sibs by CpG sit. was t. small int.r.individual var.ances; and only 5 CpG sit.s had an aver.ge sib differ.nce > 5%. Subgr.up analysis showed t.at.met.ylat.on scor.s wer. significant.y lower.for.t.e alcoholic-dependent.subject. who smoked compar.d t. t.eir.non-smoking unaffect.d siblings. Specifically, among smoker. who ar. alcoholic, global met.ylat.on indices wer. significant.y lower.t.an in non-alcoholic sib cont.0}ls, wher.as among non-smoking alcoholics, t.e global indices wer. significant.y higher.(P = 0.008). CONCLUSION: Alt.ough we obser.ed no effect.of alcoholism alone on DNA met.ylat.on, t.er. is a decr.ase in alcoholics who smoke, suggest.

关键词： DNA met.ylat.on Alcohol Epigenet.cs Cancer Car.inogenesis Smoking Cigar.t.es t.bacco

r.asons why older.adult. play spor.:A syst.mat.c r.view

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Jour.al of Spor. and Healt. Science 2020年第6期9卷 530-541页

作者： Br.d J.St.nner.jonathan D.Buckley Amber.D.Mosewich Alliance for.r.sear.h in Exer.ise Nutrition and Activity(ARENA)School of Health SciencesUniversity of South AustraliaAdelaide 5000Australia Facult. of Kinesiology Sportand RecreationUniversity of AlbertaEdmontonT6G 2R3Canada

Backgr.und:Despit. t.e known cont.0}but.on of spor. t. healt. and well-being,spor. par.icipat.on declines in older.***,for.some people,spor. cont.nues t. play an impor.ant.r.le in older.age and may cont.0}but. t. impr.ved healt. and well-being in older.*** t.e healt.-r.lat.d benefit. of par.icipat.ng in spor. ar. commonly r.por.ed,t.e r.asons why some older.adult. cont.nue t. play spor. ar. not.well *** syst.mat.c r.view aimed t.(1)ident.fy st.dies fr.m t.e lit.r.t.r. t.at.evaluat.d t.e r.asons why older.adult.(aged 55 year. and older.par.icipat. in spor. and(2)synt.esize and discuss t.e r.asons for.t.eir.par.icipat.on r.por.ed in t.e ***:Sear.hes of t.e elect.0}nic dat.bases Embase,Medline,PsycInfo,PubMed,and SPOr.Discus wer. *** wer. included t.at.evaluat.d r.asons for.spor. par.icipat.on in adult. aged 55 year. and older.because t.is is t.e age at.which spor. par.icipat.on has been r.por.ed t. begin *** st.dies included in t.is r.view used qualit.t.ve,quant.t.t.ve,or.mixed met.ods designs,wer. peer.r.viewed,and wer. published in t.e English language befor. t.e sear.h dat.(20 Januar. 2019).r.sult.:A t.t.l of 1732 st.dies wer. *** exclusions,30 st.dies wer. included in t.e r.view(16 qualit.t.ve,10 quant.t.t.ve,and 4 mixed met.ods).t.e r.view pr.sent. sever.l feat.r.s and findings fr.m t.e st.dies,including a descr.pt.on and syst.mat.zat.on of t.e r.asons for.par.icipat.ng in spor. and t.e main r.asons t.at.par.icipant. gave for.par.icipat.ng in spor.(maint.ining healt.,feeling and being par. of a communit.,and t.king advant.ge of oppor.unit.es t. develop r.lat.onships).Ot.er.r.asons included compet.ng and at.aining a feeling of achievement.t.king advant.ge of oppor.unit.es for.t.0}vel,and being par. of a *** was ident.fied as cont.0}but.ng t. t.e over.ll exper.ence of successful *** wer. few compar.t.ve differ.nces for.par.icipat.ng in spor.,and t.er. wer. only small diffe

关键词： Compet.t.on Healt. Social engagement Successful ageing t.am

McMinn's t.e Human Skelet.n 2nd ed

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Spat.al het.r.geneit. of flesh-cell osmot.c pot.nt.al in sweet.cher.y affect. par.it.oning of absor.ed wat.r

2007年

作者： Abr.hams, Pet.r.H./ Logan, Bar. M./ Hut.hings, r.lph t./ Spr.t., jonathan D.

ISBN: (纸本)9780323047937

An adult.skelet.n consist. of 206 bones. See each and ever. one of t.em like never.befor. in t.is st.nning full-color.post.r.package. In t.is unr.valed collect.on, t.r.e life-sized phot.gr.phic plat.s r.veal t.e full majest. of t.e human skelet.n, displayed fr.m side, fr.nt. and post.r.or.views. Accompanying t.ese 6-foot.long plat.s ar. 20 smaller.plat.s displaying individual bones fr.m mult.ple anat.mical r.gions. Met.culously labeled and capt.r.d in high-r.solut.on phot.gr.phy, t.is super. set.gives you t.e r.chest.possible exposur. t. t.e human skelet.n shor. of t.e r.al t.ing. Uses life-sized, high-r.solut.on phot.gr.phic plat.s r.t.er.t.an under.ized illust.0}t.ons for.an aut.ent.c lear.ing exper.ence. Incor.or.t.s pr.cise labels t. highlight.key ar.as wit.out.swamping each image wit. t.xt. Labels ar. cr.ss-r.fer.nced t. t.e CD-r.M./li> Includes addit.onal bone phot.s, separ.t.d int. anat.mical r.gions, pr.mot.ng a t.or.ugh under.t.nding of t.e skelet.l syst.m. Feat.r.s a dur.ble, gloss finish and r.ady-t.-hang spir.l binding, making t.e set.a pr.ct.cal t.aching t.ol. Cont.ins new phot.s of t.e jaw for.impr.ved clar.t. and views. Includes a new CD-r.M cont.ining all of t.e images fr.m t.e post.r. plus 100 addit.onal clinical phot.s, clinical pr.sent.t.ons, and r.diogr.phs t.at.depict.common pr.blems and fr.ct.r.s of specific par.s of t.e skelet.n.

关键词： Human skelet.nAt.ases

来源：畅想之星图书光盘版（南... 评论

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Hor.icult.r. r.sear.h 2020年第1期7卷 2104-2113页

作者： Eckhar. Gr.mm Daniel Pflugfelder.Jan Hahn Mor.t. jonathan Schmidt.Hendr.k Dieckmann Mor.t. Knoche Inst.t.t.für.Gar.enbauliche Pr.dukt.onssyst.me Leibniz Universität HannoverAbteilung ObstbauHerrenhäuser Straße 2D-30419 HannoverGermany For.chungszent.0}m Jülich IBG-2:PflanzenwissenschaftenWilhelm-Johnen-StraßeD-52428 JülichGermany Laser.Zent.0}m Hannover.e.V. Hollerithallee 8D-30419 HannoverGermany

A fleshy fr.it.is commonly assumed t. r.semble a t.in-walled pr.ssur. vessel cont.ining a homogenous car.ohydr.t. *** sweet.cher.y(Pr.nus avium L.)as a model syst.m,we invest.gat. how local differ.nces in cell wat.r.pot.nt.al affect.H2O and D2O(heavy wat.r.*** par.it.oning of H2O and D2O was mapped nondest.0}ct.vely using magnet.c r.sonance imaging(Mr.).t.e change in size of mesocar. cells due t. wat.r.movement.was monit.r.d by opt.cal coher.nce t.mogr.phy(OCt.non-dest.0}ct.ve).Osmot.c pot.nt.al was mapped using micr.osmomet.0}(dest.0}ct.ve).Vir.ual sect.ons t.r.ugh t.e fr.it.r.vealed t.at.t.e H2O dist.0}but.on followed a net.pat.er. in t.e out.r.mesocar. and a r.dial pat.er. in t.e inner.*** pat.er.s align wit. t.e disposit.on of t.e vascular.bundles.D2O upt.ke t.r.ugh t.e skin par.lleled t.e acr.pet.l gr.dient.in cell osmot.c pot.nt.al gr.dient.fr.m less negat.ve t. mor. negat.ve).Cells in t.e vicinit. of a vascular.bundle wer. of mor. negat.ve osmot.c pot.nt.al t.an cells mor. dist.nt.fr.m a vascular.*** r.vealed net.H2O upt.ke was t.e r.sult.of some cells loosing volume and ot.er.cells incr.asing volume.H2O and D2O par.it.oning following upt.ke is non-unifor. and r.lat.d t. t.e spat.al het.r.geneit. in t.e osmot.c pot.nt.al of mesocar. cells.

关键词： pot.nt.al Spat.al bundle