检索结果-南通市图书馆

Biofabrication of nanocomposite-based scaffolds containing human bone extracellularmatrix for the differentiation of skeletal stem and progenitor cells

引用

Bio-Design and Manufacturing 2024年第2期7卷 121-136页

作者： Yang-Hee Kim Janos M.Kanczler Stuart Lanham Andrew Rawlings Marta Roldo Gianluca Tozzi jonathan i.dawson Gianluca Cidonio Richard O.C.Oreffo Faculty of Medicine Bone and Joint Research GroupCentre for Human DevelopmentStem Cells and RegenerationInstitute of Developmental SciencesUniversity of SouthamptonSouthampton SO166YDUK School of Pharmacy and Biomedical Science University of PortsmouthPortsmouth PO12DTUK School of Engineering Faculty of Engineering and ScienceUniversity of GreenwichGreenwich ME44TBUK Center for Life Nano-and Neuro-Science(CLN2S) Italian Institute of Technology00161 RomeItaly

Autograft or metal implants are routinely used in skeletal ***,they fail to provide long-term clinical resolution,necessitating a functional biomimetic tissue engineering *** use of native human bone tissue for synthesizing a biomimeticmaterial inkfor three-dimensional(3D)bioprintingof skeletal tissueis anattractivestrategyfor ***,human bone extracellular matrix(bone-ECM)offers an exciting potential for the development of an appropriate microenvironment for human bone marrow stromal cells(HBMSCs)to proliferate and differentiate along the osteogenic *** this study,we engineered a novel material ink(LAB)by blending human bone-ECM(B)with nanoclay(L,Laponite®)and alginate(A)polymers using extrusion-based *** inclusion of the nanoﬁller and polymeric material increased the rheology,printability,and drug retention properties and,critically,the preservation of HBMSCs viability upon *** composite of human bone-ECM-based 3D constructs containing vascular endothelial growth factor(VEGF)enhanced vascularization after implantation in an ex vivo chick chorioallantoic membrane(CAM)*** inclusion of bone morphogenetic protein-2(BMP-2)with the HBMSCs further enhanced vascularization and mineralization after only seven *** study demonstrates the synergistic combination of nanoclay with biomimetic materials(alginate and bone-ECM)to support the formation of osteogenic tissue both in vitro and ex vivo and offers a promising novel 3D bioprinting approach to personalized skeletal tissue repair.

关键词： Extracellular matrix Nanoclay Bone 3D bioprinting

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biofabrication and biomanufacturing in ireland and the UK

引用

Bio-Design and Manufacturing 2024年第6期7卷 825-856页

作者： Jack F.Murphy Martha Lavelle Lisa Asciak Ross Burdis Hannah J.Levis Cosimo Ligorio Jamie Mc Guire Marlene Polleres Poppy O.Smith Lucinda Tullie Juan Uribe-Gomez Biqiong Chen jonathan i.dawson Julien E.Gautrot Nigel M.Hooper Daniel J.Kelly Vivian S.W.Li Alvaro Mata Abhay Pandit James B.Phillips Wenmiao Shu Molly M.Stevens Rachel L.Williams James P.K.Armstrong Yan Yan Shery Huang Department of Engineering University of CambridgeCambridge CB21PZUK Department of Translational Health Sciences Bristol Medical SchoolUniversity of BristolBristol BS13NYUK Department of Biomedical Engineering University of StrathclydeGlasgow G40NWUK Department of Materials Institute of Biomedical EngineeringImperial College LondonLondon SW72AZUK Department of Bioengineering Institute of Biomedical EngineeringImperial College LondonLondon SW72AZUK Department of Eye and Vision Science Institute of Life Course and Medical SciencesUniversity of LiverpoolLiverpool L78TXUK Biodiscovery institute University of NottinghamNottingham NG72RDUK Department of Chemical and Environmental Engineering University of NottinghamNottingham NG72RDUK Centre for Human Development Stem Cells and RegenerationHuman Development and HealthFaculty of MedicineUniversity of SouthamptonSouthampton S0166YDUK Division of Neuroscience School of Biological SciencesFaculty of BiologyMedicine and HealthUniversity of ManchesterManchester M139PTUK UCL Centre for Nerve Engineering Department of PharmacologyUCL School of PharmacyUniversity College LondonLondon WC1N 1AXUK Stem Cell and Cancer Biology Laboratory The Francis Crick InstituteLondon NW11ATUK CÚRAM SFI Research Centre for Medical DevicesUniversity of GalwayGalway H91 W2TYIreland School of Mechanical and Aerospace Engineering Queen’s University BelfastBelfast BT95AHUK School of Engineering and Materials Science Queen Mary University of LondonLondon E14NSUK Geoffrey Jefferson Brain Research Centre Manchester Academic Health Science CentreNorthern Care Alliance and University of ManchesterManchester M139PLUK Trinity Centre for Biomedical Engineering Trinity Biomedical Sciences InstituteTrinity College DublinDublin 2Ireland Department of Mechanical Manufacturing and Biomedical EngineeringSchool of EngineeringTrinity College DublinDublin 2Ireland Advanced Materials and Bioengineering Research Centre(AMBER) Royal College of Surgeons in Ireland and T

As we navigate the transition from the Fourth to the Fifth industrial Revolution,the emerging fields of biomanufacturing and biofabrication are transforming life sciences and *** sectors are benefiting from a synergy of synthetic and engineering biology,sustainable manufacturing,and integrated design *** techniques such as 3D bioprinting,tissue engineering,directed assembly,and self-assembly are instrumental in creating biomimetic scaffolds,tissues,organoids,medical devices,and biohybrid *** field of biofabrication in the United Kingdom and ireland is emerging as a pivotal force in bioscience and healthcare,propelled by cutting-edge research and *** on the production of biologically functional products for use in drug delivery,in vitro models,and tissue engineering,research institutions across these regions are dedicated to innovating healthcare solutions that adhere to ethical standards while prioritising sustainability,affordability,and healthcare system benefits.

关键词： Bioprinting Drug delivery Biomaterials Tissue engineering Sustainability Biohybrid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

1 Gbps free-space deep-ultraviolet communications based on Ⅲ-nitride micro-LEDs emitting at 262 nm

引用

Photonics Research 2019年第7期7卷 19-25页

作者： Xiangyu He Enyuan Xie Mohamed Sufyan islim Ardimas Andi Purwita jonathan J.D.McKendry Erdan Gu Harald Haas Martin D.dawson institute of Photonics Department of PhysicsUniversity of StrathclydeGlasgow G11RDUK Li-Fi R&D Centre the University of EdinburghInstitute for Digital CommunicationsEdinburgh EH9 3JLUK

The low modulation bandwidth of deep-ultraviolet(UV) light sources is considered as the main reason limiting the data transmission rate of deep-UV communications. Here, we present high-bandwidth Ⅲ-nitride microlight-emitting diodes(μLEDs) emitting in the UV-C region and their applications in deep-UV communication systems. The fabricated UV-C μLEDs with 566 μm2 emission area produce an optical power of 196 μW at the 3400 A∕cm2 current density. The measured 3 dB modulation bandwidth of these μLEDs initially increases linearly with the driving current density and then saturates as 438 MHz at a current density of 71 A∕cm2, which is limited by the cutoff frequency of the commercial avalanche photodiode used for the measurement. A deep-UV communication system is further demonstrated. By using the UV-C μLED, up to 800 Mbps and 1.1 Gbps data transmission rates at bit error ratio of 3.8 × 10-3 are achieved assuming on-off keying and orthogonal frequency-division multiplexing modulation schemes, respectively.

关键词： communications Ⅲ-nitride micro-LEDs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Erbium-doped TeO2-coated Si3N4 waveguide amplifiers with 5 dB net gain

引用

Photonics Research 2020年第6期8卷 127-134页

作者： HENRY C.FRANKiS HAMiDU M.MBONDE dawson B.BONNEViLLE CHENGLiN ZHANG RiCHARD MATEMAN ARNE LEiNSE jonathan D.B.BRADLEY Department of Engineering Physics Mc Master UniversityHamilton L8S 4L7Canada Lioni X international BV Enschede AL 7500The Netherlands

We demonstrate 5dB net gain in an erbium-doped tellurium-oxide-coated silicon nitride *** amplifier design leverages the high refractive index and high gain in erbium-doped tellurite glass as well as the ultralow losses and mature,reliable,and low-cost fabrication methods of silicon nitride waveguide *** show that the waveguide platform demonstrates low background propagation losses of 0.25dB/cm based on a ring resonator device with a Q factor of 1.3×10^6 at 1640 *** measure 5dB peak net gain at 1558 nm and>3dB of net gain across the C band in a 6.7 cm long waveguide for 35 m W of launched 1470 nm pump *** per unit length of 1.7 and 1.4dB/cm is measured in a 2.2 cm long waveguide for 970 and 1470 nm pump wavelengths,*** simulations predict that>10dB gain can be achieved across the C band simply by optimizing waveguide length and fiber-chip *** results demonstrate a promising approach for the monolithic integration of compact erbium-doped waveguide amplifiers on silicon nitride chips and within silicon-based photonic integrated circuits.

关键词： waveguide pump amplifiers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

10 Gbps wavelength division multiplexing using UV-A, UV-B, and UV-C micro-LEDs

引用

Photonics Research 2022年第2期10卷 516-523页

作者： Daniel M.Maclure jonathan J.D.McKendry Mohamed Sufyan islim Enyuan Xie Cheng Chen Xiaobin Sun Xudong Liang Xiaohui Huang Hanaa Abumarshoud Johannes Herrnsdorf Erdan Gu Harald Haas Martin D.dawson institute of Photonics Department of PhysicsSUPAUniversity of StrathclydeGlasgow G11RDUK LiFi Research and Development Centre Department of Electronic&Electrical EngineeringUniversity of StrathclydeTechnology&Innovation CentreGlasgow G11RDUK Fraunhofer Center of Applied Photonics Technology&Innovation CentreGlasgow G11RDUK Zhixin Semiconductor(Hangzhou)Co. Ltd.Hangzhou 311200China

Deep ultraviolet(DUV) optical wireless communications have seen increased interest in recent years due to the unique properties of light in this spectral region. However, the reported DUV data rates remain significantly lower than comparable demonstrations at visible wavelengths due to lower modulation bandwidths and/or output power of the sources. Here, we present a wavelength division multiplexing demonstration using three UV microlight-emitting diodes emitting at nominal peak wavelengths of 285, 317, and 375 nm, respectively, each with an emitting area of approximately 1369 μm^(2)(equivalent to circular device pixels of diameter;0 μm). Using orthogonal frequency division multiplexing, data rates of 4.17, 3.02, and 3.13 Gbps were achieved from the 285, 317, and 375 nm devices, respectively, for a combined data rate of 10.32 Gbps transmitted over a distance of 0.5 m.

关键词： Gbps multiplexing diodes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：