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Protective Role of Golden Flaxseed (Linum usitatissimum L.) Against Oxidative Damage in Lipids and Proteins of Healthy Volunteers

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Journal of Biosciences and Medicines 2015年第10期3卷 45-53页

作者： Luisa Zuravski Ritiele Pinto Coelho jonathaline apollo duarte Manoelly Oliveira Rocha Juliana Mezzomo Bruna Cocco Pilar Leandro Leal Galarca Margareth Linde Athayde Aline Augusti Boligon Michel Mansur Machado Vanusa Manfredini Postgraduate Program in Biochemistry Federal University of PampaUruguaianaBrazil Course of Pharmacy Federal University of PampaUruguaianaBrazil Postgraduate Program in Pharmaceutical Sciences Federal University of PampaUruguaianaBrazil Postgraduate Program in Pharmaceutical Sciences Federal University of Santa MariaSanta MariaBrazil

Flaxseed (Linum usitatissimum L.) is composed mainly of bioactive components such as polyphenols, polyunsaturated fatty acids, fiber and lignans. Flaxseed can be found in different presentation forms (grain or flour) and varieties (brown or golden);however, questions have arisen as to whether the presentation form and/or variety may influence the health effects. The objective of this study was to evaluate the effects on blood pressure, anthropometric and oxidative parameters in healthy human volunteers. All subjects received 40 gram aliquots of flaxseed and were instructed to consume them in their entirety mixed with water in the morning for a period of 14 days. Oxidative parameters showed significant reductions (p < 0.05) in oxidative damage to lipids and proteins via dietary intervention with golden flaxseed grains. There were no significant differences in anthropometric parameters, blood pressure, DNA damage and micronuclei frequency after 14-day supplementation. This research indicates that golden flaxseed grains can be a valuable adjunct for disease prevention and protecting the organism against oxidative damage.

关键词： Golden Flaxseed Grains Antioxidant Oxidative Damage

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