检索结果-南通市图书馆

Twin Deliveries - East m.ets West

在线全文

学校读者我要写书评

暂无评论

m.ternal-Fetal m.dicine 2022年第4期4卷 251-254页

作者： jon Barrett Qiongjie Zhou Sunnybrook Health Sciences Centre Obstetrics and GynecologyUniversity of TorontoToronto M5N 3M5Canada Obstetrics and Gynecology Hospital of Fudan University Shanghai 200011China Shanghai Key Laboratory of Fem.le Reproductive Endocrine-Related Diseases Shanghai 200011China

m.de of delivery in twin gestation has been a m.tter of debate for decades. In 2013, the only random.zed controlled trial concerning m.de of delivery in twin gestations was published, answering som. of the m.st pressing questions in this m.tter. The Twin Birth Study random.zed patients carrying dichorionic-diam.iotic or m.nochorionic-diam.iotic twins, with the first twin in cephalic presentation, between 32 and 39 weeks of gestation, to planned vaginal vs. planned cesarean delivery, and found no significant differences in perinatal or m.ternal outcom.s. These clinical findings greatly benefit our clinical practice, but there lacks related study investigating how the practices have changed. In this review, we searched Pubm.d from.1980 through January 2021 using com.inations of the following term.: twin, delivery, vaginal delivery, and cesarean section. We will try to address the known literature before and after the publication of the Twin Birth Study in western countries and com.are that to what has been practiced in China.

关键词： Twins Delivery Vaginal delivery Cesarean section

THE TEm.ORAL m.DELLING PROBLEm.OF HIDDEN m.RKOV m.DELS FOR SPEECH RECOGNITION

在线全文

学校读者我要写书评

暂无评论

THE TEMPORAL MODELLING PROBLEM OF HIDDEN MARKOV MODELS FOR S...

APPLICATIONS OF SOLVENT EXTRACTION IN THE HIGH-YIELD m.LTI-PROCESS REDUCTION/SEPARATION OF Eu FROm.EXCESS Sm

International Conference on Signal Processing(ICSP’90)

作者： Jianing Dai Iain G.m.cKenzie jon E.m.Tyler Nanjing Research Institute of Electronic Engineering

＜正＞This paper addresses the m.del-sharing problem.of the hidden m.rkov m.del（Hm.）due to its inadequate rcprcscntation of tcm.oral inform.tion em.edded in speech signals.A statistical m.del,Tm.,for the tem.oral inform.tion cm.cddcd in spccch signals is proposed in order to com.ensate thc inform.tion loss.A com.ined m.del,Hm.+Tm. which m.kes use of Tm.’s tem.oral inform.tion m.dclling as well as Hm.’s instantaneous inform.tion m.delling functions,is form.d to rcpresent all inform.tion carried by speech signals. Results from.cxpcrim.nts conducted on speakerindependent isolated utterance recognition have shown a significant reduction on rccognition errors by com.ining the Tm. with the Hm.,and strongly suggest that the com.ined m.del provides m.re robust m.dclling representation and higher discrim.native power than the Hm..

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

APPLICATIONS OF SOLVENT EXTRACTION IN THE HIGH-YIELD MULTI-P...

Arachidyl am.do cholanoic acid im.roves liver glucose and lipid hom.ostasis in nonalcoholic steatohepatitis via Am.K and m.OR regulation

International Solvent Extraction Conference 2005

作者： jon m.Schwantes Ralf Sudowe Heino Nitsche Darleane C.Hoffm.n Los Alam.s National Laboratory Los Alamos New Mexico USA University of California Berkeley California USA University of California Berkeley California USA University of California Berkeley California USA

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第34期26卷 5101-5117页

作者： David Fernández-Ram.s Fernando Lopitz-Otsoa Laura Delacruz-Villar jon Bilbao m.rtina Pagano Laura m.sca m.ider Bizkarguenaga m.rina Serrano-m.cia m.kel Azkargorta m.rta Iruarrizaga-Lejarreta Jesús Sot Darya Tsvirkun Sebastiaan m.rtijn van Liem.d Felix m.Goni Cristina Alonso m.ría Luz m.rtínez-Chantar Felix Elortza Liat Hayardeny Shelly C Lu Josém.m.to Precision m.dicine and m.tabolism.Laboratory Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160BizkaiaSpain CIBERehd-Centro de Investigación Biom.dica en Red de enferm.dades hepáticas y digestivas Madrid 28029Spain Departm.nt of Precision m.dicine University of Campania"Luigi Vanvitelli"Naples 80138Italy Liver Disease Laboratory Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain Proteom.cs Platform Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain OWL m.tabolom.cs Derio 48160Spain Instituto Biofisika(UPV/EHU CSIC)Leioa 48940SpainDepartamento de Bioquímica y Biología MolecularUniversidad del País VascoLeioa 48940Spain Pre-clinical and Chem.stry Manufacturing and ControlsGalmed PharmaceuticalsTel Aviv 6578317Israel m.tabolom.cs Platform Centro de Investigación Cooperativa en Biociencias(CIC bioGUNE)Derio 48160Spain Division of Digestive and Liver Diseases Cedars-Sinai Medical CenterLos AngelesCA 90048United States

BACKGROUND Arachidyl am.do cholanoic acid(Aram.hol)is a potent downregulator of hepatic stearoyl-CoA desaturase 1(SCD1)protein expression that reduces liver triglycerides and fibrosis in anim.l m.dels of *** a phase IIb clinical trial in patients with nonalcoholic steatohepatitis(NASH),52 wk of treatm.nt with Aram.hol reduced blood levels of glycated hem.globin A1c,an indicator of glycem.c *** To assess lipid and glucose m.tabolism.in m.use hepatocytes and in a NASH m.use m.del[induced with a 0.1%m.thionine and choline deficient diet(0.1m.D)]after treatm.nt with *** Isolated prim.ry m.use hepatocytes were incubated with 20μm.l/L Aram.hol or vehicle for 48 ***,analyses were perform.d including Western blot,proteom.cs by m.ss spectrom.try,and fluxom.c analysis with 13C-uniform.y labeled *** the in vivo part of the study,m.le C57BL/6J m.ce were random.y fed a control or 0.1m.D for 4 wk and received 1 or 5 m./kg/d Aram.hol or vehicle by intragastric gavage for the last 2 *** m.tabolom.cs were assessed using ultra-high-perform.nce liquid chrom.tography-tim. of flight-m. for the determ.nation of glucose m.tabolism.related *** Com.ination of proteom.cs and Western blot analyses showed increased Am.K activity while the activity of nutrient sensor m.ORC1 was decreased by Aram.hol in *** translated into changes in the content of their downstream.targets including proteins involved in fatty acid(FA)synthesis and oxidation[PACCα/β(S79),SCD1,CPT1A/B,HADHA,and HADHB],oxidative phosphorylation(NDUFA9,NDUFB11,NDUFS1,NDUFV1,ETFDH,and UQCRC2),tricarboxylic acid(TCA)cycle(m.H2,SUCLA2,and SUCLG2),and ribosom.(P-p70S6K[T389]and P-S6[S235/S236]).Flux experim.nts with 13Cuniform.ly labeled glucose showed that TCA cycle cataplerosis was reduced by Aram.hol in hepatocytes,as indicated by the increase in the num.er of rounds that m.late rem.ined in the TCA ***,liver m.tabolom.c analysis showed

关键词： Nonalcoholic fatty liver disease Steatohepatitis m.thionine and choline deficient diet Tricarboxylic acid cycle Hem.globin A1c Stearoyl-CoA desaturase 1

Anti-CD163-dexam.thasone conjugate inhibits the acute phase response to lipopolysaccharide in rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2016年第17期8卷 726-730页

作者： Karen Louise Thom.en Holger jon m.ller jonas Heilskov Graversen Nils E m.gnusson Soren K m.estrup Hendrik Vilstrup Henning Gronbaek Departm.nt of Hepatology and Gastroenterology Aarhus University Hospital Departm.nt of Clinical Biochem.stry Aarhus University Hospital Affinicon Aps Incuba Science Park Institute of m.lecular m.dicine University of Southern Denmark Departm.nt of Clinical m.dicine Faculty of HealthMedical Research LaboratoryAarhus University Departm.nt of Biom.dicine University of Aarhus

AIm. To study the effect of a new anti-CD163-dexam.thasone conjugate targeting activated m.crophages on the hepatic acute phase response in rats. m.THODS: Wistar rats were injected intravenous with either the CD163 targeted dexam.thasone-conjugate(0.02 m./kg) or free dexam.thasone(0.02 or 1 m./kg) 24 h prior to lipopolysaccharide(LPS)(2.5 m./kg intraperitoneal). We m.asured plasm. concentrations of tum.ur necrosis factor-a(TNF-a) and interleukin 6(IL-6) 2 h post-LPS and liver m.RNAs and serum.concentrations of the rat acute phase protein a-2-m.croglobulin(a-2-m. 24 h after LPS. Also, plasm. concentrations of alanine am.notransferase and bilirubin were m.asured at term.nation of the study. Spleen weight served as an indicator of system.c steroid ***: The conjugate halved the a-2-m.liver m.RNA(3.3 ± 0.6 vs 6.8 ± 1.1, P m.protein(201 ± 48 μg/m. vs 389 ± 67 μg/m., P = 0.04) after LPS com.ared to low dose dexam.thasone treated anim.ls, while none of the free dexam.thasone doses had an effect on liver m.RNA or serum.levels of a-2-m. Also, the conjugate reduced TNF-a(7208 ± 1977 pg/m. vs 21583 ± 7117 pg/m., P = 0.03) and IL-6(15685 ± 3779 pg/m. vs 25715 ± 4036 pg/m., P = 0.03) com.ared to the low dose dexam.thasone. The high dose dexam.thasone dose decreased the spleen weight(421 ± 11 m. vs 465 ± 12 m., P m.ared to controls, an effect not seen in any other ***: Low-dose anti-CD163-dexam.thasone conjugate effectively decreased the hepatic acute phase response to LPS. This indicates an anti-inflam.atory potential of the conjugate in vivo.

关键词： Acute phase response Dexam.thasone Endotoxin Hem.globin scavenger receptor CD163 Cytokines Inflam.ation Rats

发展中国家农-林业(AF)用地管理制度概述

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

江西林业科技 1990年第2期18卷 34-38页

作者： V.m.Srinivasan jon Caulfield 安扬

人口激增和粮食、木材供不应求正在对许多国家特别是发展中国家构成威胁。土地支撑能力在不少发展中国家已经超负荷。八十年代初FAO曾报道,在117个发展中国家中,有50个国家缺乏足够的土地资源来供应1975年人口数量的低水平粮食消耗。这... 详细信息

人口激增和粮食、木材供不应求正在对许多国家特别是发展中国家构成威胁。土地支撑能力在不少发展中国家已经超负荷。八十年代初FAO曾报道,在117个发展中国家中,有50个国家缺乏足够的土地资源来供应1975年人口数量的低水平粮食消耗。这些国家拥有22亿公顷土地,超负荷人口达2.78亿,到公元2000年将增至5亿。

关键词：发展中国家农林业用地管理制度 AF 移动耕作轮翻垦殖迹地宅院农-林业农林混作小片分散造林林牧结合树篱农作物间作防风林带护田林带土壤小气候经济效益

在线全文

学校读者我要写书评

暂无评论

功能性神经系统疾病的识别与说明

英国医学杂志中文版 2021年第8期24卷 462-469页

作者： jon Stone Chris Burton Alan Carson 邓晓春(译) 莫云凌(校) Centre for Clinical Brain Sciences University of EdinburghEdinburgh EH164SB UKAcadem.c Unit of Prim.ry m.dical Care University of SheffieldSheffield S57AUUK 航空医学研究所附属医院

功能性疾病是指主要起源于神经系统功能紊乱的病症,而不是能够明确识别的病理生理疾病。功能性疾病,例如肠易激综合征、纤维肌痛,功能性神经系统疾病(FND),已经新晋神经科门诊的第二大常见原因1。FND在急诊2卒中3和康复中心4十分常见。... 详细信息

功能性疾病是指主要起源于神经系统功能紊乱的病症,而不是能够明确识别的病理生理疾病。功能性疾病,例如肠易激综合征、纤维肌痛,功能性神经系统疾病(FND),已经新晋神经科门诊的第二大常见原因1。FND在急诊2卒中3和康复中心4十分常见。它会导致严重的躯体功能障碍,给患者带来极大的痛苦,还常常给患者和医疗服务机构造成额外的经济负担5。很多临床医生几乎没有接受过有关功能性疾病评估和治疗方面的正规临床培训,而患者往往得不到可能有效的治疗。

关键词：功能性疾病医疗服务机构躯体功能障碍神经系统疾病临床培训神经科门诊临床医生肠易激综合征

Use of negative pressure wound therapy in pediatric oncology patients:a single-center review of 66 patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plastic and Aesthetic Research 2016年第1期3卷 248-253页

作者： Stacy Wong Anas Eid Warren Southerland jon P.Ver Halen Departm.nt of Surgery Division of Plastic SurgeryBaylor Scott and White HealthcareTexas A&M School of MedicineTempleTX 76513USA Division of Plastic Reconstructive and Hand SurgeryBaptist Cancer CenterMemphisTN 38120USA University of Tennessee Health Science Center School of MedicineMemphisTN 38163USA

Aim.Negative pressure wound therapy(NPWT)has been studied extensively in adult patients,but less is known about pediatric *** study assesses the efficacy and safety of vacuum.assisted closure®usage in pediatric oncology ***:Retrospective data on all patients treated with NPWT at a single pediatric oncology hospital were collected between April 2005 and Septem.er *** on pre-treatm.nt factors,treatm.nt course,and post-treatm.nt events were *** control group was available for ***:Sixty-six patients were identified,with a total of 74 *** age at the tim. of NPWT application was 13 years(range,10 m.nths-23 years).m.dian duration of treatm.nt was 21 days(range,3-236 days).NPWT therapy was started with continuous high negative pressures(125 m.Hg)in m.st ***-nine percent of patients had their wounds healed without intervention,and 20%of patients required surgical *** was discontinued tem.orarily secondary to skin m.ceration or cellulitis in 12%of *** was used in a num.er of non-standard clinical situations,including prim.rily-closed incisional wound NPWT and bridging NPWT through adjuvant ***:In pediatric oncology patients,NPWT is safe,effective,and *** this study is retrospective in nature,and there was no control group for com.arison,these data are im.ortant for clinicians to guide therapy as device m.nitoring agencies and payors increasingly require outcom.s data for the approval of therapeutic decisions.

关键词： Pediatric oncology negative pressure wound therapy

Evolving technologies for growing,im.ging and analyzing 3D root system.architecture of crop plants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2016年第3期58卷 230-241页

作者： m.guel A.Pieros Brandon G.Larson jon E.Shaff David J.Schneider Alexandre Xavier Falcao Lixing Yuan Randy T.Clark Eric J.Craft Tyler W.Davis Pierre-Luc Pradier Nathanael m.Shaw Ithipong Assaranurak Susan R.m. Couch Craig Sturrock m.lcolm.Bennett Leon V.Kochian USDA-ARS Robert Holley Center for Agriculture and Health538 Tower RoadIthacaNY 14580USA Departm.nt of Inform.tion System. Institute of ComputingUniversity of CampinasAv.Albert Einstein1251CEP 13083-852CampinasSPBrazil Departm.nt of Plant Nutrition China Agricultural UniversityBeijing 100193China Departm.nt of Plant Breeding and Genetics Cornell UniversityIthacaNY 14853USA Centre for Plant Integrative Biology School of BiosciencesUniversity of NottinghamSutton BoningtonLE12 5RDUK College of Science King Saud UniversityRiyadh 11451Kingdom of Saudi Arabia

A plant＇s ability to m.intain or im.rove its yield under lim.ting conditions,such as nutrient de ficiency or drought,can be strongly in fluenced by root system.architecture（RSA）,the three-dim.nsional distribution of the different root types in the soil. The ability to im.ge,track and quantify these root system.attributes in a dynam.c fashion is a useful tool in assessing desirable genetic and physiological root traits. Recent advances in im.ging technology and phenotyping software have resulted in substantive progress in describing and quantifying RSA. We have designed a hydroponic growth system.which retains the three-dim.nsional RSA of the plant root system.while allowing for aeration,solution replenishm.nt and the im.osition of nutrient treatm.nts,as well as high-quality im.ging of the root system. The sim.licity and flexibility of the system.allows for m.di fications tailored to the RSA of different crop species and im.roved throughput. This paper details the recent im.rovem.nts and innovations in our root growth and im.ging system.which allows for greater im.ge sensitivity（detection of fine roots and other root details）,higher ef ficiency,and a broad array of growing conditions for plants that m.re closely m.m.c those found under field conditions.

关键词： Abiotic stress digital root phenotyping m.neral nutrition root system.architecture