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Outcomes of a non-randomised audit of single pigtail suture stents in urolithiasis management of Asian patients in Singapore

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Asian Journal of Urology 2024年第2期11卷 324-330页

作者： Ee Jean lim Zhen Wei Choo Reshma Mangat Pradeep Durai Sarvajit Biligere Yiquan Tan Loh Hin Yeung Marcus Nicole Andrea Seet Li Ting Chin Tiong Heng Stefania Ferreti Vineet Gauhar Urology Department Singapore General HospitalSingapore Urology Department Tan Tock Seng HospitalSingapore Urology Department Ng Teng Fong HospitalSingapore Urology Department Azienda Ospedaliera-Uiversitaria(Hospital and University of Parma)ParmaItaly

Objective:Double-J(DJ)ureteric stents are commonly placed perioperatively for semirigid or flexible ureteroscopic renal *** is believed that lesser stent material within the bladder mitigates stent-related *** study aimed to evaluate the J-Fil ureteral stent,a single pigtail suture stent compared with conventional DJ stent in relation to stent symptoms in an Asian population undergoing ureterorenal ***:Based on internal audit committee recommendation approval,the records of 50 patients retrieved,available data of 41 patients who were prospectively enrolled into two groups(Group 1[J-Fil stent group],n=21 and Group 2[DJ stent group],n=20)between August 2020 to January 2021,were *** compared were nature of procedure,stone location and size,ease of deployment or removal,and complications.A modified universal stent symptom questionnaire was used to assess morbidity of stent symptoms within 48 h of insertion and at ***:Both groups had similar median age,distribution in male to female ratio,and stone *** overall median universal stent symptom questionnaire score at insertion was similar for bladder pain,flank or loin pain,and quality of life between Group 1 and 2;however,at removal Group 1 fared significantly better than Group 2,especially for flank or loin pain and pain at *** groups had similar ease in insertion with no hospital ***:Our audit favoured the single pigtail suture stent in Asian ureters in mitigating stent-related *** showed a good safety profile with easy deployment and *** promises a new standard in stenting.

关键词： Stent Ureteroscopy Pigtail suture stent Asianpatient Flexible ureteroscopic renal surgery

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聚酯合成催化技术的研究进展

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高校化学工程学报 2024年第1期38卷 1-13页

作者：王翼嵩王松林姜冰雪李家旭邓维史胜斌 lim Khak Ho 王青月杨轩刘平伟王文俊浙江大学化学工程联合国家重点实验室浙江杭州310058 浙江大学衢州研究院浙江衢州324000 浙江恒逸石化有限公司浙江杭州311209

聚酯工业的进步离不开先进的催化技术。本文对聚酯合成催化体系的研究进展进行了评述。着眼于目前占主导的金属催化剂,对锑、钛、锡、锗、铝等催化剂在活性、副反应等方面所开展的金属复合、配体改性、载体负载等工作进行了总结,介绍了... 详细信息

聚酯工业的进步离不开先进的催化技术。本文对聚酯合成催化体系的研究进展进行了评述。着眼于目前占主导的金属催化剂,对锑、钛、锡、锗、铝等催化剂在活性、副反应等方面所开展的金属复合、配体改性、载体负载等工作进行了总结,介绍了有机物、离子液体、酶等非金属催化体系的研究进展,并对促进聚酯合成的电、光、微波等催化辅助技术进行了评述。催化能力强、副反应少、聚合条件温和催化体系的开发有助于聚酯品质的提升,将先进的表征手段、模型研究以及聚酯构效关系规律探索结合到催化体系的研究中,可加速高效聚酯催化技术的研发。

关键词：聚酯金属催化剂缩聚开环聚合非金属催化剂

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基于拉曼光谱技术的聚合物材料制备与组成分布的研究进展

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高校化学工程学报 2024年第3期38卷 341-353页

作者：卫人予陈八斤邓维吴徐冰包界杰张浩然吴彬王小君 lim Khak Ho 王文俊浙江大学工程师学院衢州分院浙江衢州324000 浙江大学衢州研究院浙江衢州324000 浙江传化化学集团浙江杭州311215 化学工程联合国家重点实验室(浙江大学) 浙江杭州310058

聚合物材料制备过程和聚合物中添加剂的含量及分布决定了材料的性能,拉曼光谱技术为相关研究提供了一种有效的表征手段。基于拉曼光谱的基本原理,介绍了表面增强拉曼光谱、拉曼光谱成像、激光显微共聚焦拉曼光谱等多种拉曼光谱衍生技术... 详细信息

聚合物材料制备过程和聚合物中添加剂的含量及分布决定了材料的性能,拉曼光谱技术为相关研究提供了一种有效的表征手段。基于拉曼光谱的基本原理,介绍了表面增强拉曼光谱、拉曼光谱成像、激光显微共聚焦拉曼光谱等多种拉曼光谱衍生技术,总结了相关技术在聚合物加工和聚合反应过程中的应用,评述了聚合物中添加剂分布的检测,涵盖了乳化剂、染料以及其他添加剂的浓度、分布及迁移规律等,并对拉曼光谱衍生技术进行了展望。

关键词：拉曼光谱显微拉曼光谱拉曼光谱成像技术聚合物材料添加剂

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Viral-host molecular interactions and metabolic modulation:Strategies to inhibit flaviviruses pathogenesis

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World Journal of Virology 2024年第4期13卷 41-50页

作者： Zeeshan Ahmad Khan Mukesh Kumar Yadav Dong-Woo lim Hojun Kim Jing-Hua Wang AbuZar Ansari Biohealth Products Research Center(BPRC) Research Center for Agedlife Redesign(RCAR)Department of Physical TherapyINJE UniversityGimhae 5084South Korea Department of Microbiology Central University of PunjabBathinda 151401India Department of Diagnostics College of Korean MedicineDongguk UniversityGoyang 10326South Korea Division of Rehabilitation Medicine of Korean Medicine Department of Oriental Rehabilitation MedicineDongguk UniversityIlsan HospitalGoyang 10326South Korea Institute of Oriental Medicine Dongguk UniversityGoyang 10326South Korea Department of Obstetrics and Gynecology Ewha Womans UniversitySeoul 07985South Korea

Flaviviruses,which include globally impactful pathogens,such as West Nile virus,yellow fever virus,Zika virus,Japanese encephalitis virus,and dengue virus,contribute significantly to human *** the ongoing emergence and resurgence of flavivirus-mediated pathogenesis,the absence of specific therapeutic options remains a challenge in the prevention and treatment of flaviviral *** the intricate processes of fusion,transcription,replication,and maturation,the complex interplay of viral and host metabolic interactions affects *** interactions involve metabolic molecules,such as amino acids,glucose,fatty acids,and nucleotides,each playing a pivotal role in the replication and maturation of *** viral-host metabolic molecular interactions hijack and modulate the molecular mechanisms of host metabolism.A comprehensive understanding of these intricate metabolic pathways offers valuable insights,potentially unveiling novel targets for therapeutic interventions against flaviviral *** review emphasizes promising avenues for the development of therapeutic agents that target specific metabolic molecules,such as amino acids,glucose,fatty acids,and nucleotides,which interact with flavivirus replication and are closely linked to the modulation of host *** clinical limitations of current drugs have prompted the development of new inhibitory strategies for flaviviruses based on an understanding of the molecular interactions between the virus and the host.

关键词： Flavivirus Nonstructural proteins Virus-host interaction Metabolism Inhibitors Vaccines

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Evaluation of Functional and Radiological Outcome of Arthroscopic-Assisted Anatomical Coracoclavicular (CC) and Acromioclavicular (AC) Ligament Reconstruction in Chronic AC Joint Dislocation

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Journal of Biosciences and Medicines 2024年第3期12卷 223-237页

作者： Muhammad Hafiz Daud lim Wee Cheong Ang Xi Yuan Che Wan Mohd Shaiful Nizam Siti Hawa Tahir Arthroscopy Sports Injury Unit Orthopedic Department Hospital Kuala Lumpur Kuala Lumpur Malaysia

Introduction: Acromioclavicular (AC) joint dislocation is a common shoulder injury, comprising 9% - 12% of shoulder girdle injuries. Optimal management remains challenging, with treatment decisions guided by the Rockwood classification system. Controversies surround grade III injuries, necessitating further classification. Non-operative treatment has shown favorable outcomes, while surgical interventions vary. Anatomical coracoclavicular reconstruction (ACCR) has demonstrated biomechanical advantages over traditional methods. Arthroscopic techniques offer advantages, minimizing deltoid detachment and allowing concurrent pathology identification. This study evaluates the outcomes of arthroscopic-assisted ACCR in chronic AC joint dislocation. Surgical Technique: Arthroscopic-assisted ACCR involves meticulous portal placement, tendon graft harvesting, diagnostic arthroscopy, and coracoid exposure. The clavicle tunnels were made to mimic the conoid and trapezoid ligament positions, using FibreTape#2 loop and Dog Bone Button for correct placement against the coracoid base, and passing the semitendinosus graft through to reconstruct the conoid ligament, reduction done and graft follow through for anatomical reconstruction. Methods: A retrospective cohort study at Hospital Kuala Lumpur analyzed 35 patients undergoing arthroscopic-assisted ACCR for Rockwood grade III - V AC joint dislocations. Inclusion criteria encompassed trauma ≥ 3 weeks prior, no prior shoulder injuries, and ≥12-month follow-up. Functional and radiological assessments utilized ASES scores and coracoclavicular distances, respectively. Statistical analysis employed descriptive statistics and logistic regression. Results: The mean age was 38.9 years (SD 11.26), and 34 of 35 patients were male. Grade IV injuries were predominant (37.1%). Waiting time for surgery averaged 234.9 days. Functional improvement was substantial postoperatively (ASES: 55.5 to 88.9). Radiological outcomes demonstrated reduced coraco

关键词： Arthroscopic-Assisted Anatomical Coracoclavicular and Acromioclavicular Ligament Reconstruction (AACR) Chronic Acromioclavicular Dislocation ASES Score Rockwood Classification

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Performance of pulsed plasma thruster at low discharge energy

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Plasma Science and Technology 2024年第4期26卷 122-132页

作者：李鸿俊林泽豪胡浩俊吴文东陈爱虹杜德扬 Department of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Faculty of Engineering The University of Nottingham Malaysia CampusSemenyih 43500Malaysia Faculty of Engineering Multimedia UniversityCyberjaya 63100Malaysia

As the size of satellites scales down, low-power and compact propulsion systems such as the pulsed plasma thruster(PPT) are needed for stabilizing these miniature satellites in orbit. Most PPT systems are operated at 2 J or more of discharge energy. In this work, the performance of a PPT with a side-fed, tongue-flared electrode configuration operated within a lower discharge energy range of 0.5-2.5 J has been investigated. Ablation and charring of the polytetrafluoroethylene propellant surface were analyzed through field-effect scanning electron microscopy imaging and energy-dispersive X-ray spectroscopy. When the discharge energy fell below 2 J, inconsistencies occurred in the specific impulse and the thrust efficiency due to the measurement of the low mass bit. At energy ≥2 J, the performance parameters are compared with other PPT systems of similar configuration and discussed in depth.

关键词： pulsed plasma thruster low discharge energy performance parameters

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Combination therapy with methylprednisolone,rituximab,and tofacitinib in antimelanoma differentiation-associated 5 gene dermatomyositis with rapidly progressive interstitial lung disease

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Rheumatology & Autoimmunity 2024年第2期4卷 122-125页

作者： Mona Manghani Weiyen lim Gin Tsen Chai Xin Rong lim Choon Guan Chua Department of Rheumatology Allergy and ImmunologyTan Tock Seng HospitalSingapore CitySingapore Department of Preventative and Population Medicine Tan Tock Seng HospitalSingapore CitySingapore Department of Respiratory Medicine Tan Tock Seng HospitalSingapore CitySingapore Department of Respiratory MedicineTan Tock Seng HospitalSingapore CitySingapore

To the Editor,Anti-melanoma differentiation-associated gene 5(anti-MDA5)antibody-associated dermatomyositis(DM)presenting with rapidly progressive interstitial lung disease(RP-ILD)is extremely challenging to ***5 is a cytosolic viral RNA sensor that normally triggers an innate response resulting in interferon I *** of MDA5 expression can result in autoantibody formation,leading to overactivation of the type I interferon pathway,causing aberrant metabolic remodeling of peripheral B and T cells and a profibrotic response in the affected lungs.

关键词： interferon melanoma lung

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Nutritional and therapeutic benefits of coconut milk and its potential as a plant-based functional yogurt alternative: a review

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Food Science and Human Wellness 2024年

作者： Gengghatarani Gengan Nurul Solehah Mohd Zaini Nazamid Saari Anis Shobirin Meor Hussin Ahmad Haniff Jaafar Hanan Hasan Elicia Jitming lim Wan Abd Al Qadr Imad Wan-Mohtar Muhamad Hafiz Abd Rahim Functional Omics and Bioprocess Development Laboratory， Institute of Biological Sciences， Faculty of Science， Universiti Malaya Faculty of Food Science and Technology， Universiti Putra Malaysia School of Life and Environmental Sciences， The University of Sydney

Plant-based milks are on the rise due to an increased awareness of their sustainability and health benefits. Currently， dairy milk is the most nutritionally complete beverage， but it suffers from the presence of indigestible lactose and allergenic proteins. Coconut milk has been around for a long time， but its application is limited due to a perceived lack of specific nutrients， high saturated fat levels， and low acceptability. Recent evidence indicates， however， that the saturated fat and other plant-based components found in coconut milk are good for metabolic outcomes and brain health. The conversion of coconut milk to yoghurt will further improve its functionality by boosting its existing nutritional qualities. In this article， the nutritional value of coconut milk， as well as its potential downsides， its application as yoghurt， and suggestions for enhancing its nutritional functionality will be examined.

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钢悬链线立管全尺寸共振弯曲疲劳试验系统与模态分析

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振动与冲击 2024年第20期43卷 119-127页

作者：徐泽鑫安晨谢智张吉祥林方坚中国石油大学(北京)安全与海洋工程学院北京102249 里约热内卢联邦大学阿尔韦托·路易斯·科英布拉工程研究学院海洋工程系里约热内卢21941-972 2H海洋工程有限公司伦敦GU216HJ

钢悬链线立管(steel catenary riser,SCR)作为支撑海上平台和其他关键设备的重要组成部分,在极端的海洋环境中长时间服役运行时,其结构完整性和安全性至关重要。为确保SCR立管在恶劣环境下的安全运行,对立管进行共振弯曲疲劳试验研究成... 详细信息

钢悬链线立管(steel catenary riser,SCR)作为支撑海上平台和其他关键设备的重要组成部分,在极端的海洋环境中长时间服役运行时,其结构完整性和安全性至关重要。为确保SCR立管在恶劣环境下的安全运行,对立管进行共振弯曲疲劳试验研究成为必要的评估标准,同时也为后续立管疲劳寿命预测和失效分析提供基础。针对两种特定型号的SCR立管,推导并求解不同约束条件下的共振系统的固有频率与振型函数,分析管道长度、管道壁厚、偏心块和配重块质量对共振系统固有频率的影响;在此基础上开展不同特定工况下的全尺寸共振弯曲疲劳试验,同时对SCR立管在全尺寸共振弯曲疲劳试验系统中不同跨距及内压的振动响应特性进行了模拟。结合理论分析、有限元计算和共振弯曲疲劳试验结果,发现管道长度和两端的配重约束是影响共振系统1阶固有频率的重要参数,特别是在管道长度较短和壁厚较薄的情况下,影响更为显著。此外,注水加压和跨距增加会降低共振系统的固有频率,支撑跨距越短,系统的固有频率越大。分析所得结果为SCR立管的共振弯曲疲劳试验系统结构设计和试验方案优化提供了重要的参考依据。

关键词：钢悬链线立管(SCR) 共振弯曲疲劳试验固有频率全尺寸模态特性

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“房子”与“身份”——奈保尔《毕司沃斯先生的房子》

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外国语文研究 2024年第2期10卷 32-40页

作者：林宛莹厦门大学外文学院

奈保尔的小说《毕司沃斯先生的房子》书写了主人公毕司沃斯终生追求“房子”的奇特现象。本文运用文学伦理学批评方法,探讨了小说中主人公毕司沃斯追求“房子”的原因,揭示了毕司沃斯追求“房子”与“身份”探寻之间的密切关系。本文认... 详细信息

奈保尔的小说《毕司沃斯先生的房子》书写了主人公毕司沃斯终生追求“房子”的奇特现象。本文运用文学伦理学批评方法,探讨了小说中主人公毕司沃斯追求“房子”的原因,揭示了毕司沃斯追求“房子”与“身份”探寻之间的密切关系。本文认为,毕司沃斯试图通过获得房子来确立自己作为儿子、女婿、丈夫和父亲的伦理身份,从而实现他的存在价值和人生意义。在这一意义上,小说中通过揭示“房子”与“身份”的关系也展现了空间的伦理意义。通过对空间伦理的关注,本文强调了小说中的“房子”不仅仅是房子,它在本质的意义上具有“独立自主”“个人尊严”“人生成就”“责任与义务”的伦理价值。

关键词：奈保尔《毕司沃斯先生的房子》身份文学伦理学批评

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