Two-dime.sional(2D)transition me.al dichalcoge.ide.(TMD)are.atomically thin se.iconductors with promising optoe.e.tronic applications across the.visible.***,the.r intrinsically we.k light absorption and the.low photol...
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Two-dime.sional(2D)transition me.al dichalcoge.ide.(TMD)are.atomically thin se.iconductors with promising optoe.e.tronic applications across the.visible.***,the.r intrinsically we.k light absorption and the.low photolumine.ce.ce.quantum yie.d(PLQY)re.trict the.r pe.formance.and pote.tial use.e.pe.ially in ultraviole.(UV)wave.e.gth light *** dots(QD)de.ive. from 2D mate.ials(2D/QD)provide.e.ficie.t light absorption and e.ission of which e.e.gy can be.tune. for de.irable.light *** this study,we.gre.tly e.hance. the.photon absorption and PLQY of monolaye.(1L)tungste. disulfide.WS_(2))in the.UV range.via hybridization with 2D/QD,particularly titanium nitride.MXe.e.QD(Ti_(2)N MQD)and graphitic carbon nitride.QD(GCNQD).With the.hybridization of MQD or GCNQD,1LWS_(2)showe. a maximum PL e.hance.e.t by 15 time. with 300 nm wave.e.gth e.citation,while.no notice.ble.e.hance.e.t was obse.ve. whe. the.e.citation photon e.e.gy was le.s than the.bandgap of the.QD,indicating that UV absorption by the.QD playe. a crucial role.in e.hancing the.light e.ission of 1L-WS_(2)in our 0D/2D hybrid *** findings pre.e.t a conve.ie.t me.hod for e.hancing the.photo-re.ponse.of 1L-WS_(2)to UV light and offe. e.citing possibilitie. for harve.ting UV e.e.gy using 1L-TMD.
AIMTo e.aluate.e.ficacy/safe.y of he.atitis C virus (HCV) prote.se.inhibitor boce.re.ir with pe.ylate. inte.fe.on (Pe.-IFN) alfa and we.ght-base. ribavirin (RBV) in a phase.3 trial. Me.HODSA prospe.tive. multice.te., ...
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AIMTo e.aluate.e.ficacy/safe.y of he.atitis C virus (HCV) prote.se.inhibitor boce.re.ir with pe.ylate. inte.fe.on (Pe.-IFN) alfa and we.ght-base. ribavirin (RBV) in a phase.3 trial. Me.HODSA prospe.tive. multice.te., phase.3, ope.-labe., single.arm study of Pe.-IFN alfa, we.ght-base. RBV, and boce.re.ir, with a Pe.-IFN/RBV le.d-in phase.was pe.forme.. The.HCV/human immunode.icie.cy virus coinfe.te. study population include. tre.tme.t naïve.(TN) and tre.tme.t e.pe.ie.ce. (Te. patie.ts. Tre.tme.t duration range. from 28 to 48 wk de.e.de.t upon re.ponse.guide. crite.ia. All patie.ts had HCV Ge.otype.1 with a viral load > 10000 IU/mL. Compe.sate. cirrhosis was allowe.. Sample.size.was de.e.mine. to e.tablish supe.iority to historical (Pe.-IFN plus RBV) rate. in sustaine. viral re.ponse.(SVR). Re.ULTSA total of 257 e.rolle. participants we.e.analyze. (135 TN and 122 Te.. In the.TN group, 81.5% we.e.male.and 54.1% we.e.black. In the.Te.group, 76.2% we.e.male.and 47.5% we.e.white. Ove.all SVR12 rate. (HCV RNA P = 0.002). Among the.TN, SVR12 was 42.1% among white. and 27.4% among blacks (P = 0.09). CONCLUSIONThe.trial me. its hypothe.is of improve. SVR compare. to historical controls but ove.all SVR rate. we.e.low. All-oral HCV tre.tme.ts will mitigate.the.e.difficultie..
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