检索结果-南通市图书馆

Scale,Information-Processing,and Complementarities in Old-World Axial Age Societies

在线全文

学校读者我要写书评

暂无评论

Journal of Social Computing 2022年第2期3卷 119-127页

作者： Ian morris the Department of Classics Stanford UniversityStanfordCA 94305-2145USA

Recent cross-disciplinary work on quantifying historical dynamics has made major contributions to ***,efforts to specify relationships between scale and information-processing always run a risk of shoehorning messy realities into overly rigid *** the case of the first-millennium BCE“Axial Age”in the Old World,networks of collective computing were structured more by cultural systems than by polities,and to understand the relationships between political scale and collective computational abilities,scholars need categories flexible enough to clarify the complementarities between political and cultural systems.

关键词： scale information-processing Axial Age ancient Greece

Transmission of Knowledge and Practice between Cultures:A Case Study of Chinese Medicine Integration in the United States

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medicine and Culture 2022年第4期5卷 202-207页

作者： William morris AOMA Graduate School of Integrative Medicine Austin 78745USA

Medicine operates within the world views of the culture that it serves,and the widespread Chinese diaspora has carried medical practices with *** resulting creolization takes shape at the borders of intersecting cultures in a distinct form of *** article explores the intersections of integration relative to the spread of Chinese medicine in the United States in practical,cognitive,and theoretical *** article could be a reference to practitioners,academics,and policymakers in the areas of integrative and Chinese medicine.

关键词： Acupuncture Culture ICD-11 Integrative medicine Sociology Traditional Chinese medicine Transdisciplinarity

The presence of functional blood vessels in the ischemic core provides a therapeutic target for stroke recovery

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第12期18卷 2653-2654页

作者： Gary P.morris Brad A.Sutherland Tasmanian School of Medicine College of Health and MedicineUniversity of TasmaniaHobartTasmaniaAustralia

Ischemic stro ke occurs when a blood vessel in the brain is *** the immediate *** flow becomes deficient in regions supplied by the blocked *** leads to the development of a core region,where blood flow is reduced to ... 详细信息

关键词： al. therapeutic maintain

Redox regulation of the immune response

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第10期19卷 1079-1101页

作者： Gerwyn morris Maria Gevezova Victoria Sarafian Michael Maes Deakin University IMPACT-the Institute for Mental and Physical Health and Clinical TranslationSchool of MedicineBarwon HealthGeelongVICAustralia Department of Medical Biology Medical University-PlovdivPlovdivBulgaria Research Institute at Medical University-Plovdiv PlovdivBulgaria Department of Psychiatry Faculty of MedicineKing Chulalongkorn Memorial HospitalBangkokThailand Department of Psychiatry Medical University of PlovdivPlovdivBulgaria

The immune-inflammatory response is associated with increased nitro-oxidative *** aim of this mechanistic review is to examine:(a)the role of redox-sensitive transcription factors and enzymes,ROS/RNS production,and the activity of cellular antioxidants in the activation and performance of macrophages,dendritic cells,neutrophils,T-cells,B-cells,and natural killer cells;(b)the involvement of high-density lipoprotein(HDL),apolipoprotein A1(ApoA1),paraoxonase-1(PON1),and oxidized phospholipids in regulating the immune response;and(c)the detrimental effects of hypernitrosylation and chronic nitro-oxidative stress on the immune *** redox changes during immune-inflammatory responses are orchestrated by the actions of nuclear factor-κB,HIF1α,the mechanistic target of rapamycin,the phosphatidylinositol 3-kinase/protein kinase B signaling pathway,mitogen-activated protein kinases,5'AMP-activated protein kinase,and peroxisome proliferator-activated *** performance and survival of individual immune cells is under redox control and depends on intracellular and extracellular levels of ROS/*** are heavily influenced by cellular antioxidants including the glutathione and thioredoxin systems,nuclear factor erythroid 2-related factor 2,and the HDL/ApoA1/PON1 *** nitro-oxidative stress and hypernitrosylation inhibit the activity of those antioxidant systems,the tricarboxylic acid cycle,mitochondrial functions,and the metabolism of immune *** conclusion,redox-associated mechanisms modulate metabolic reprogramming of immune cells,macrophage and T helper cell polarization,phagocytosis,production of pro-versus anti-inflammatory cytokines,immune training and tolerance,chemotaxis,pathogen sensing,antiviral and antibacterial effects,Toll-like receptor activity,and endotoxin tolerance.

关键词： Oxidative and nitrosative stress Immune response Inflammation Antioxidants Physiological stres

A case of phenibut withdrawal and treatment with baclofen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第4期14卷 338-340页

作者： Michael morris James Espinosa Alan Lucerna Robin Lahr Department of Emergency Medicine Rowan University SOM/Jefferson StratfordNJ 08084USA Emergency Medicine Residency Program Director Rowan University SOM/Jefferson StratfordNJ 08084USA

Phenibut(β-phenyl-γ-aminobutyric acid)is a psychoactive gamma-aminobutyric acid(GABA)analog marketed online as a nutritional and nootropic(cognition enhancing)*** consumption poses a high risk of potential *** from phenibut mimics benzodiazepine and alcohol withdrawal and can be dangerous.A number of approaches have been described for phenibut withdrawal,including protocols that include baclofen,but for inpatient and outpatient *** we describe a 30-year-old male who presented to an emergency department(ED)with insomnia,anxiety and palpitations after he stopped taking phenibut.

关键词： treatment withdrawal alcohol

Parkinson's disease: From genetics to molecular dysfunction and targeted therapeutic approaches

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2023年第3期10卷 786-798页

作者： Yue Huang Jun Wei Antony Cooper Margaret J.morris China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of Pharmacology School of Medical SciencesFaculty of Medicine&HealthUNSWSydneyNSW 2052Australia The Garvan Institute of Medical Research SydneyNSW 2010Australia St Vincent's Clinical School Faculty of Medicine&Healthand School of Biotechnology and Biomolecular SciencesFaculty of ScienceUNSWSydneyNSW 2052Australia

Parkinson's disease (PD) is the most common neurodegenerative movement disorder in the elderly. As the pathogenesis of PD is still not fully understood, medications with the capacity of halting the disease progression are currently unavailable. The discovery of genes that are causative for, or increase susceptibility to PD is pivotal for the development of novel therapeutic approaches, as they are critical for the onset of PD and the molecular pathways underlying its pathogenesis. By reviewing relevant data, we discuss causative genes, and those associated with PD susceptibility and quantitative traits. Through Gene Ontology database and STRING analysis, we emphasize the roles of inorganic cation transmembrane transport pathways and hypothalamic pituitary thyroid axis, in addition to the established roles of inflammation/oxidative stress and mitochondrial dysfunction in the pathogenesis of PD. It is hoped these insights 1) untangle the clinical complex presentations of PD, 2) reveal the interwoven molecular network leading to PD, and 3) identify critical molecular targets to facilitate novel PD drug discovery, with a view to providing improved consultation and personalized medicine for patients with PD in the future.

关键词： Drug discovery Genetics Molecular function Parkinson's disease Quantitative traits

A Techno-Economical Characterization of Solar PV Power Generation in Rwanda:The Role of Subsidies and Incentives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy Engineering 2023年第9期120卷 2155-2175页

作者： morris Kayitare Gace Athanase Dalson Al-Mas Sendegeyad African Center of Excellence in Energy for Sustainable Development University of RwandaKigaliRwanda African Center of Excellence for Sustainable Cooling and Cold Chain University of RwandaKigaliRwanda Department of Agricultural Mechanization School of Agriculture EngineeringUniversity of RwandaNyagatareRwanda Department of Electrical and Electronics Engineering Kyambogo UniversityKampalaUganda

Standalone Solar PV systems have been vital in the improvement of access to energy in many ***,given the large cost of solar PV plants’components,in developing countries,there is a dear need for such components to be subsidised and incentivised for the consumers to afford the produced ***,there is a need for optimal sizing of the solar PV plants taking into account the solar information,energy requirement for various activities,and economic conditions in the off-grid regions in *** study aims to develop optimally sized solar PV plants suited to rural communities in ***,it aims at characterizing the impacts of subsidies and incentives on the profitability and affordability of solar PV plants’energy in *** the study,we have developed a model on basis of which the plant power(peak power)and costs of energy can be predicted given the load requirements using *** model was validated using data corrected at eight different *** generalized predictive model’s results matched the results obtained using field measurement data as *** models have been able to replicate with a by degree of accuracy the peak powers and the plants’costs for different loads and were used to evaluate the economic viability of solar PV plants in *** was found that with incentives and subsidies of 20%,the solar PV systems’costs,the Levelised Cost of Energy would drop from a maximum of 0.098 Euro to a minimum of 0.072 Euro,the payback period was reduced from a maximum of 7.5 years to a minimum of 6.0 years while the return on investments was seen to vary between 425.72 and 615.32 per cent over the plants’lifetime of 25 *** our findings underscore the importance of government subsidies and incentives for solar PV energy generation projects to be significantly profitable.

关键词： Techno-economical characterization solar PV plants solar-energy economy PV energy generation energy in Rwanda

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

尼日利亚博尔诺州的粮食安全问题研究

尼日利亚博尔诺州的粮食安全问题研究

作者： Simone morris 浙江师范大学

学位级别：硕士

虽然每个国家都在努力满足本国人民的饮食需求,但是粮食安全问题在世界范围内仍普遍存在。自然灾害、环境退化、局势动荡等因素造成了全球的饥荒问题。大多数国家认为饥荒的主要原因之一是农业部门生产力低下。因此,各国目前正在实施各... 详细信息

虽然每个国家都在努力满足本国人民的饮食需求,但是粮食安全问题在世界范围内仍普遍存在。自然灾害、环境退化、局势动荡等因素造成了全球的饥荒问题。大多数国家认为饥荒的主要原因之一是农业部门生产力低下。因此,各国目前正在实施各种方案和项目来提升本国农业部门的能力,使得粮食产量达到能够满足人民需求的水平。为了解决全球的饥荒问题,实现“零饥饿”(Zero Hunger)的目标。联合国在2015年推出了17项可持续发展项目(SDG 2)。为了实现“零饥饿”的目标,尼日利亚曾执行了若干旨在改善农业生产的全国政策和方案。然而,尽管采取了多项措施,尼日利亚目前仍存在粮食安全问题。尤其是在博尔诺州,有数百万居民面临着粮食安全问题。博尔诺州农业部门遭到严重破坏是该州粮食安全问题严重的主要原因,在社会、环境和政治因素共同作用下加剧了粮食安全问题。首先,博尔诺农业部门的机械化和技术发展水平极低,该州许多农民仍然使用原始的生产工具,这拉低了该州的粮食生产水平。其次,博科圣地叛乱和农牧冲突的导致大量农田被毁,中断了该州的粮食生产。再次,政策执行不力和资源分配不善也加剧了粮食安全问题。虽然该州出台了许多农业政策,但没有发挥显著作用。最后,该州本土人民长期不良的耕种习惯以及乍得湖的缩小也导致了粮食产量难以提升。另外,性别歧视问题阻碍了女性务农也阻碍了该州粮食产量的提高。博尔诺州的粮食安全问题非常严重,甚至部分地区遭受了严重的饥荒,许多家庭也存在营养不良问题。博尔诺居民对此采取了各种应对措施,如让儿童退学、从事非法活动、出售土地和乞讨食物。然而,这些措施并不能解决粮食安全问题。不仅博尔诺州,尼日利亚全国都受到了粮食危机的影响。尼日利亚社会各个层面都因此受到了影响。农村贫困率上升,公众对国家和州政府失去信心。博尔诺居民营养不良和贫血率不断攀高,该村居民严重发育不良。博尔诺州要克服粮食安全问题,首先需要解决粮食生产和分配问题。其次,国际援助和投资也有助于提高粮食产量,博尔诺可以采取本地情况和国际援助结合的方案来解决粮食危机。美国、中国等国在农业领域有丰富的知识,尼日利亚又与这些国家有着友好的关系。尼日利亚政府可以利用这些伙伴关系来改善其农业部门和粮食分配体系。

关键词：尼日利亚博尔诺粮食安全问题政策援助

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

萨塔玛活动中心芬兰科特卡

世界建筑导报 2024年第2期39卷 77-81页

作者： Juho Grönholm Antti Nousjoki Samuli Woolston Sampo Honkala Chris morris Ricardo Cruz Recalde Mirja Sillanpää Niklas Mahlberg Thomas Miyauchi Stephanie Polochowitz Tuomas Uusheimo(摄影) ALA建筑师事务所不详

新开业的萨塔玛活动中心位于科特卡市最古老的港口坎塔萨塔玛,距离著名的维拉莫海事中心(已在港口区立足15年)只有几步之遥。该活动中心与目前正在建设的芬兰东南应用科技大学新校区大楼和未来酒店位于同一地块。这三座新建筑将有助于... 详细信息

新开业的萨塔玛活动中心位于科特卡市最古老的港口坎塔萨塔玛,距离著名的维拉莫海事中心(已在港口区立足15年)只有几步之遥。该活动中心与目前正在建设的芬兰东南应用科技大学新校区大楼和未来酒店位于同一地块。这三座新建筑将有助于加强港口与城市中心之间的视觉和功能联系。该活动中心是举办各种文化、体育和商务活动的理想场所。ALA建筑师事务所的设计工作侧重于将极具吸引力的建筑与功能性和环境目标相结合。其建筑特征来源于环境和项目目标。

关键词：活动中心建筑师事务所大学新校区港口区科特萨塔功能性芬兰