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Ecological Processes 2024年第1期13卷 176-187页

作者： Han Li Pauline Allen Saige Boris Samantha Lagrama Jade Lyons Christina Mills Pauline Moussi Casey Nichols Carter Tacosik mc Kenzie Tsaousis Nyzaya Livingston Wilson john F.grider Kevin A.Parker Matina C.Kalcounis-Rueppell Department of Biology University of Nebraska Omaha Department of Biology University of North Carolina Greensboro Colorado Parks and Wild-life Parker Ecology LLC Department of Biological Sciences University of Alberta

Background The timing of behavior and habitat use of nocturnal animals can be influenced by the lunar cycle in nature. The prevalence of artificial light at night(ALAN) has been recognized as a source of environmental pol-lution. The interaction between ALAN and the lunar cycle on bat behavior is important for understanding anthro-pogenic effects on bats. We utilized a decade(2012–2022) of acoustic monitoring data collected in North Carolina, United States, to investigate the relationship between bat activity, lunar cycle, and light pollution. We examined whether the amount of lunar illumination affected species-specific nightly activity and whether hourly bat activity patterns varied between nights with different moon phases. We further investigated if the relationship between bat activity and the lunar cycle might be altered by light *** We found that seven bat species showed activity variation across nights in relation to the amount of moon illumination when ALAN was absent. In general, bats were less active on full moon nights compared to new moon nights. Light pollution interacted with the bat–lunar relationship in five of the seven species, masking the effect of the lunar cycle. We identified delayed bat activity patterns on nights with a full or waxing moon in seven species, and light pollution altered that pattern in four species. Overall, ALAN was associated with decreased bat activity inde-pendent of lunar cycle *** Our study demonstrated that at a broad spatial scale, ALAN negatively affected many North American temperate bat species and altered their lunar chronobiology. As light pollution is spreading to historically dark areas and habitats, ALAN might couple with other threats, such as the white-nose syndrome or climate change, to cause cascading damage in the environment that depends on ecosystem services such as pest control provided by bats. We argue that further research and conservation actions are needed to mitigate

关键词： Artificial light at night ALAN Bats Chiroptera Chronobiology Light pollution Lunar cycle Moonlight

C19mc miRNA-520g induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma

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genes & Diseases 2024年第1期11卷 60-63页

作者： goodwin g.Jinesh Marian T.Smallin Nino Mtchedlidze Isha godwin Marco Napoli Nicole Hackel Manali S.Phadke Avani A.Deshpande Xiaobo Li john H.Lockhart Jaden R.Baldwin Suehelay Acevedo-Acevedo Yifeng gao Michelle A.Reiser Keiran S.M.Smalley Elsa R.Flores Andrew S.Brohl Department of Molecular Oncology H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Molecular Medicine Program H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Saveetha Medical College ChennaiTamil Nadu 602105India Tumor Biology Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Sarcoma Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA

SP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of SP100 and promotes its degradation(Table S1).Interferon(IFN)signaling could still produce more SP100 through transcription to counteract viruses.1 Viruses also disable the transcriptional up-regulation of SP100 to achieve persistent infection in hosts.

关键词： SP100 melanoma stabilization

geochemistry and mineralogy of beach sediments in the northern gulf of Mexico,Tamaulipas state,Mexico:implication for provenance

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Journal of Palaeogeography 2024年第3期13卷 375-400页

作者： Mayank Shukla Sanjeet K.Verma Mayla A.Ramos-Vázquez john S.Armstrong-Altrin Karla R.Hernández-Martínez Sumit Mishra Vivek P.Malviya Héctor Hernández-Mendoza Posgrado de la Division de geociencias Aplicadas Instituto Potosino de Investigacion Científica y Tecnologica(IPICYT)Camino a la Presa San José2055San Luis Potosí78216Mexico Division de geociencias Aplicadas Instituto Potosino de Investigación Científica y Tecnologica(IPICYT)Camino a la Presa San Jose 2055San Luis Potosí78216Mexico Universidad Nacional Autonoma de México Instituto de Ciencias del Mar y LimnologíaUnidad de ProcesosOceanicos y CosterosCiudad UniversitariaCiudad de México 04510Mexico Department of Marine Sciences Bharathidasan UniversityTiruchirappalli620024Tamil NaduIndia Instituto de geociencias Universidad Nacional Autonoma de MéxicoBoulevard Juriquilla 300176230JuriquillaQueretaroMexico Department of Applied geology Dr.Harisingh Gour Central UniversitySagar470002Madhya PradeshIndia Instituto de Investigacion de Zonas Desérticas Universidad Autònoma de San Luis PotosíAltair 200CP 78377San LuisS.L.P.Mexico Universidad del Centro de Mexico Capitán Caldera 75CP 78250San LuisS.L.P.Mexico

geochemical and mineralogical studies were performed in the La Pesca(LP)and Tesoro Altamira(TA)beach sediments,located in the Tamaulipas state,northern gulf of *** main aim of this study is to infer the weathering history and provenance and to discriminate the tectonic environment of the beach *** sediments are composed of quartz with small amounts of accessory minerals such as plagioclase,calcite,orthoclase,microcline,and *** beach sediments are classified as fine-grained and very well sorted,however LP has coarse skewed and leptokurtic sediments,whereas TA has fine-skewed and very leptokurtic *** chemical index of weathering(CIW’)indicates intense weathering in the source *** quartz grain microtextures in the LP and TA are classified into mechanical,chemical,and mechanical/chemical *** features such as fractures,pits,percussion marks,abrasion fatigue,and V-shaped marks favor high-energy littoral,fluvial,subaqueous-marine,and aeolian *** chemical features indicate solution pits and crystalline overgrowth,which suggests a silica saturated marine *** mechanical/chemical features display adhering particles and elongated depressions suggest formation in a sub-aqueous nearshore marine *** and trace elements-based provenance discrimination diagrams indicate a felsic source derived from the Mesa Central(mc),Sierra Madre Oriental(SMOr)and Oaxaquia *** major and trace element concentrations imply a passive margin setting for the northern gulf of Mexico,which is consistent with the general geology.

关键词： Beach sediments geochemistry Mineralogy Provenance Tamaulipas Tectonic setting

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Characteristics of aggregated chondrules and reclassification of Boxian meteorites

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Chinese Science Bulletin 1999年第S2期44卷 118-120页

作者： john C. Bridges Robert hutchison Department of Mineralogy Natural History Museum London SW7 5BD UK

CHONDRULES are the major constituent of chondrites, but the nature of their origin remains elusive. Models based on nebular settings have attracted much support since Wood suggested that they formed there ascondensates. Subsequently, the melting of dust in the nebula has been widely invoked. Recently,however, models suggesting that chondrules formed in parent body regoliths have been revived, couldhelp to explain the coexistence of chondrules with chemically differentiated clasts The Boxian meteorite is a fall and was originally described as L4. The widely quoted classification of the chondrite is LL4. In this study, 362 chondrules were separated from the Boxian meteorite,and were measured for their grain sizes, masses and morphologies. 101 of these chondrules were successfully split and parts of them made into polished blocks; the remaining segments were individually set asidefor future oxygen isotopic analyses. Mineralogical investigation of the 101 chondrules was performed

关键词： characteristics reclassification Boxian meteorites.

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Potential availability of non-woody biomass feedstock for pellet production within the Republic of Ireland

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International Journal of Agricultural and Biological Engineering 2010年第1期3卷 63-73页

作者： Anthony Nolan Kevin mc Donnell ger J.Devlin john P.Carroll john Finnan Biosystems Engineering UCD School of AgricultureFood Science and Veterinary MedicineUniversity College DublinBelfieldDublin 4Ireland Teagasc Crops Research Centre Oak ParkCarlowIreland

The threat of increasing fuel prices and climate change necessitates the need for clean,renewable and independent energy sources.A gIS(geographical Information Systems)model was developed using ArcgIS 9.2 to analyze the availability of non-woody biomass(wheat,oat,barley and rape straw,willow and miscanthus)for pellet production in *** within the heating and electricity sector would displace currently used fossil fuels with cleaner,carbon neutral non-woody *** aim of the analysis was to determine the total hectares of biomass within Ireland and compute the potential non-woody biomass *** greatest potential source of biomass for pelleting is cereal *** the Republic of Ireland the South-East,South-West and Mid-East of Ireland have the greatest biomass yield for pellet production and likely to be most economically ***-woody biomass has a realistic potential to displace fossil fuels within the heating and electricity sector resulting in CO2 mitigation.

关键词： biomass pellet production non-woody biomass gIS analysis renewable energy source CO2 mitigation

Reimagining large river management using the Resist–Accept–Direct(RAD) framework in the Upper Mississippi River

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Ecological Processes 2023年第4期12卷 3-22页

作者： Nicole K.Ward Abigail J.Lynch Erik A.Beever Joshua Booker Kristen L.Bouska Holly Embke Jeffrey N.Houser john F.Kocik Joshua Kocik David J.Lawrence Mary grace Lemon Doug Limpinsel Madeline R.Magee Bryan M.Maitland Owen mc Kenna Andrew Meier john M.Morton Jeffrey D.Muehlbauer Robert Newman Devon C.Oliver Heidi M.Rantala greg g.Sass Aaron Shultz Laura M.Thompson Jennifer L.Wilkening National Park Service Climate Change Response Program Habitat Conservation Division NOAA Wisconsin Department of Natural Resources Aquatic Sciences Center Center for Limnology U.S. geological Survey Northern Prairie Wildlife Research Center and Midwest Climate Adaptation Science Center U.S. Army Corps of Engineers Alaska Wildlife Alliance U.S. geological Survey Alaska Cooperative Fish and Wildlife Research Unit University of Alaska Fairbanks University of North Dakota great Lakes Indian Fish and Wildlife Commission (gLIFWC) Minnesota Department of Natural Resources U.S. geological Survey National Climate Adaptation Science Center and School of Natural Resources University of Tennessee U.S. geological Survey National Climate Adaptation Science Center U.S. geological Survey Northern Rocky Mountain Science Center Department of Ecology Montana State University U.S. Fish and Wildlife Service National Wildlife Refuge System U.S. geological Survey Upper Midwest Environmental Sciences Center U.S. geological Survey Midwest Climate Adaptation Science Center NOAA NEFSC Orono University of Nebraska-Lincoln

Background Large-river decision-makers are charged with maintaining diverse ecosystem services through unprecedented social-ecological transformations as climate change and other global stressors intensify. The interconnected, dendritic habitats of rivers, which often demarcate jurisdictional boundaries, generate complex management challenges. Here, we explore how the Resist–Accept–Direct(RAD) framework may enhance large-river management by promoting coordinated and deliberate responses to social-ecological trajectories of change. The RAD framework identifies the full decision space of potential management approaches, wherein managers may resist change to maintain historical conditions, accept change toward different conditions, or direct change to a specified future with novel conditions. In the Upper Mississippi River System, managers are facing social-ecological transformations from more frequent and extreme high-water events. We illustrate how RAD-informed basin-, reach-, and site-scale decisions could:(1) provide cross-spatial scale framing;(2) open the entire decision space of potential management approaches; and(3) enhance coordinated inter-jurisdictional management in response to the trajectory of the Upper Mississippi River *** The RAD framework helps identify plausible long-term trajectories in different reaches(or subbasins) of the river and how the associated social-ecological transformations could be managed by altering site-scale conditions. Strategic reach-scale objectives may reprioritize how, where, and when site conditions could be altered to contribute to the basin goal, given the basin's plausible trajectories of change(e.g., by coordinating action across sites to alter habitat connectivity, diversity, and redundancy in the river mosaic).Conclusions When faced with long-term systemic transformations(e.g., > 50 years), the RAD framework helps explicitly consider whether or when the basin vision or goals may no longer be achievable,

关键词： Ecosystem Management Transformation Social-ecological system Anthropocene Climate change Basin planning Cross-scale interactions

Combining Ethnography, Archival Data, and Social Network Analysis to Better Understand an Industry

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Combining Ethnography, Archival Data, and Social Network Ana...

Characterization and validation of a chronic retinal neovascularization rabbit model by evaluating the efficacy of anti-angiogenic and anti-inflammatory drugs

International Conference on Anthropological Perspectives and Local Approaches:Indigenous Applications in Management and Marketing

作者： john mc Creery The Word Works Ltd.

This paper describes a project in which I have been involved for several years,an attempt to combine social network analysis(SNA)with historical and ethnographic research(HER)to better understand the world of top creators in the Japanese advertising *** versions of the paper were presented at Sunbelt XXXII,the annual conference of the International

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International Journal of Ophthalmology(English edition) 2022年第1期15卷 15-22页

作者： Sandeep Kumar john Quach Nicholas Cook glenwood gum Vatsala Naageshwaran Department of Ophthalmology Absorption Systems:a Pharmaron company7901 Vickers StSan DiegoCA 92111USA

AIM:To establish a rabbit model with chronic condition of retinal neovascularization(RNV)induced by intravitreal(IVT)injection of DL-2-aminoadipic acid(DL-AAA),a retinal glial(Mül er)cell toxin,extensive characterization of DL-AAA induced angiographic features and the suitability of the model to evaluate anti-angiogenic and anti-inflammatory therapies for ocular vascular ***:DL-AAA(80 mmol/L)was administered IVT into both eyes of Dutch Belted *** DL-AAA delivery,clinical ophthalmic examinations were performed weekly following modified mc Donald-Shadduck Scoring *** fundus photography,fluorescein angiography(FA),and optical coherence tomography(OCT)procedures were performed every 2 or 4 wk until stable retinal vascular leakage was *** stable retinal leakage(12 wk post DL-AAA administration)was established,anti-vascular endothelial growth factor(VEgF)(bevacizumab,ranibizumab and aflibercept)and anti-inflammatory(triamcinolone,TAA)drugs were tested for their efficacy after IVT *** angiograms were scored before and after treatment following a novel grading system,developed for the DL-AAA rabbit ***:Post DL-AAA administration,eyes were presented with moderate to severe retinal/choroidal inflammation which was accompanied by intense vitreous flare and presence of inflammatory cells in the vitreous *** hemorrhage was restricted to the tips of neo-retinal *** revealed maximum retinal vascular leakage at 2 wk after DL-AAA injection and then persisted as evidenced by stable mean FA scores in weeks 8 and *** vascular angiographic and tomographic features were stable and consistent up to 36 mo among two different staggers induced for RNV at two different *** 7,mean FA scores showed that 1μg/eye of bevacizumab,ranibizumab,aflibercept and 2μg/eye of TAA suppress 65%,90%,100%and 50%retinal vascular leakage,*** 30,bevacizumab and TAA continued to show 66%and 44%su

关键词： DL-2-aminoadipic acid chronic wet agerelated macular degeneration retinal neovascularization animal model anti-vascular endothelial growth factor drugs fluorescein angiography

Synthesis of tungsten ditelluride thin films and highly crystalline nanobelts from pre-deposited reactants

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Tungsten 2020年第3期2卷 321-334页

作者： john B.mc Manus Cansu Ilhan Bastien Balsamo Clive Downing Conor P.Cullen Tanja Stimpel‑Lindner graeme Cunningham Lisanne Peters Lewys Jones Daragh Mullarkey Igor V.Shvets georg S.Duesberg Niall mcEvoy School of Chemistry Trinity College DublinDublin 2 D02 PN40Ireland AMBER Centre CRANN InstituteTrinity College DublinDublin 2 D02 PN40Ireland SIgMA Clermont UniversitéClermont Auvergne63000 Clermont–FerrandFrance Institute of Physics EIT 2Faculty of Electrical Engineering and Information TechnologyUniversität der Bundeswehr München85579 NeubibergGermany School of Physics Trinity College DublinDublin 2 D02 PN40Ireland

Tungsten ditelluride(WTe_(2))is a layered transition metal dichalcogenide(TMD)that has attracted increasing research inter-est in recent ***_(2) has demonstrated large non-saturating magnetoresistance,potential for spintronic applications and promise as a type-II Weyl *** majority of works on WTe_(2) have relied on mechanically exfoliated flakes from chemical vapour transport(CVT)-grown crystals for their *** producing high-quality samples,this method is hindered by several disadvantages including long synthesis time,high-temperature annealing and an inherent lack of *** this work,a synthesis method is demonstrated that allows the production of large-area polycrystalline films of WTe_(2).This is achieved by the reaction of pre-deposited films of W and Te at a relatively low temperature of 550℃.Sputter X-ray photoelectron spectroscopy reveals the rapid but self-limiting nature of the oxidation of these WTe_(2) films in ambient *** WTe_(2) films are composed of areas of micrometre-sized nanobelts that can be isolated and offer potential as an alternative to CVT-grown *** nanobelts are highly crystalline with low defect densities indicated by transmission electron microscopy and show promising initial electrical results.

关键词： Two-dimensional materials Tungsten ditelluride Film conversion Electrodeposition Nanoelectronics