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Repeat Rf Ablation of C2 and Third Occipital Nerves for Recurrent Occipital Neuralgia and Cervicogenic Headaches

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World Journal of Neuroscience 2016年第4期6卷 236-242页

作者： john f. Hamer Traci A. Purath Oak Brook IL USA Purath Headache and Neurology Greenfield WI USA

Objective: To address the degree and duration of pain relief from recurrent cervicogenic headaches and/or occipital neuralgia following retreatment with radiofrequency ablation of the C2 dorsal root ganglion and/or third occipital nerves;to review outcomes including duration and degree of pain relief;to evaluate procedure’s complication rate and patient’s willingness to repeat the procedure;to compare effectiveness of the most recent Rf ablation to patient’s first Rf ablation. Methods: This is a single-center retrospective observational study of 23 patients with recurrent cervicogenic headaches and/or occipital neuralgia treated with repeated Rf ablation of the C2 dorsal root ganglion and/or third occipital nerves. All patients receiving treatment from January 2010 to July 2014 are included in this single site retrospective study. This is an IRB approved medical chart review study. Results: 22 of 23 patients underwent follow-up. An average of 86.5% of participants reported pain relief on average of 25.4 weeks at time of follow-up. 41% reported side effects including suboccipital hyperesthesia and/or ear discomfort, 95% reported willingness to repeat the procedure again if severe symptoms recurred, 59% of patients reported the most recent Rf ablation had the same results as the first, 32% reported the most recent Rf was the most effective, and 9% reported that the first Rf was the most effective. Conclusion: Repeated Rf ablation is a feasible option for recurrent cervicogenic headaches and/or occipital neuralgia. Effectiveness of repeat intervention is the same or better than the first ablation. Though there was a higher likelihood of side effects including suboccipital neuralgia and/or ear discomfort on repeat treatment, the side effects were generally well tolerated.

关键词： Occipital Neuralgia Cervicogenic Headache Radiofrequency Ablation

Selling :building partnerships 3rd ed. 3rd ed.

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Comparison of the Kobayashi-Royden and Sibony metrics on ring domains

1998年

作者： Bart A. Weitz Stephen B. Castleberry john f. Tanner Jr

来源：畅想之星图书光盘版（南... 评论

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Science China Mathematics 2009年第12期52卷 2610-2616页

作者： fORN■SS john Erik Department of Mathematics University of MichiganAnn ArborMichigan 48109USA

In this paper we show that the Kobayashi-Royden metric and the Sibony metric are different on ring domains,i.e.,the difference of two concentric balls,in higher dimension.

关键词： Kobayashi-Royden metric Sibony metric ring domain 32f45 32U05

Huanglongbing:An overview of a complex pathosystem ravaging the world's citrus

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Journal of Integrative Plant Biology 2016年第4期58卷 373-387页

作者： john V.da Graca Greg W.Douhan Susan E.Halbert Manjunath L.Keremane Richard f.Lee Georgios Vidalakis Hongwei Zhao Texas A&M University--Kingsville Citrus Center WeslacoTexas 78599USA Department of Plant Pathology and Microbiology University of CaliforniaRiversideCalifornia 92521USA florida Department of Agriculture and Consumer Services Division of Plant IndustryP.O.Box 147100GainesvilleFlorida 32614USA USDA ARS National Clonal Germplasm Repository for Citrus and Dates RiversideCalifornia 92507USA College of Plant Protection Nanjing Agricultural UniversityNanjing 210095China

Citrus huanglongbing（HLB） has become a major disease and limiting factor of production in citrus areas that have become infected. The destruction to the affected citrus industries has resulted in a tremendous increase to support research that in return has resulted in significant information on both applied and basic knowledge concerning this important disease to the global citrus industry. Recent research indicates the relationship between citrus and the causal agent of HLB is shaped by multiple elements, in which host defense responses may also play an important role. This review is intended to provide an overview of the importance of HLB to a wider audience of plant biologists. Recent advances on host-pathogen interactions, population genetics and vectoring of the causal agent are discussed.

关键词： Citrus greening Diaphorina citri host response Huanglongbing(HLB) psyllid vectors

Validation of a discrete element model using magnetic resonance measurements

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Particuology 2009年第4期7卷 297-306页

作者： Christoph R.Müller Stuart A.Scott Daniel J.Holland Belinda C.Clarke Andrew J.Sederman john S.Dennis Lynn f.Gladden Department of Chemical Engineering and Biotechnology University of CambridgePembroke StreetCambridge CB2 3RAUnited Kingdom

The discrete element model （DEM） is a very promising modelling strategy for two-phase granular systems. However, owing to a lack of experimental measurements, validation of numerical simulations of two-phase granular systems is still an important issue. In this study, a small two-dimensional gas- fluidized bed was simulated using a discrete element model. The dimensions of the simulated bed were 44mm × 10mm × 120 mm and the fluidized particles had a diameter dp = 1.2 mm and density ρp = 1000 kg/m^3. The comparison between DEM simulations and experiments are performed on the basis of time-averaged voidage maps. The drag-law of Beetstra et al. [Beetstra, R., van der Hoef, M.A., ＆ Kuipers,J. A. M. （2007b）. Drag force of intermediate Reynolds number flow past mono- and bidispersed arrays of spheres. AIChE Journal, 53,489-501 ] seems to give the best results. The simulations are fairly insensitive to the coefficient of restitution and the coefficient of friction as long as some route of energy dissipation during particle-particle and particle-wall contact is provided. Changing the boundary condition of the gas phase at the side-walls from zero-slip to full-slip does not affect the simulation results. Care is to be taken that the cell sizes are chosen so that a reasonable number of particles can be found in a fluid cell.

关键词： Discrete element modelling Magnetic resonance imaging Voidage Gas-fluidized beds

QTL analysis of soft scald in two apple populations

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Horticulture Research 2016年第1期3卷 117-123页

作者： Kendra A McClure Kyle M Gardner Peter MA Toivonen Cheryl R Hampson Jun Song Charles f forney john DeLong Istvan Rajcan Sean Myles Department of Plant and Animal Sciences Faculty of AgricultureDalhousie UniversityTruroB2N 5E3Nova ScotiaCanada Department of Plant Agriculture Crop Science BuildingUniversity of GuelphGuelphN1G 2W1OntarioCanada Agriculture and Agri-food Canada Fredericton Research and Development CentreFrederictonE3B 4Z7New BrunswickCanada Agriculture and Agri-food Canada Summerland Research and Development CentreSummerlandV0H 1Z0British ColumbiaCanada Agriculture and Agri-food Canada Kentville Research and Development CentreKentvilleB4N 1J5Nova ScotiaCanada

The apple(Malus×domestica Borkh.)is one of the world’s most widely grown and valuable fruit *** demand for apples year round,storability has emerged as an important consideration for apple breeding *** scald is a cold storage-related disorder that results in sunken,darkened tissue on the fruit *** breeders are keen to generate new cultivars that do not suffer from soft scald and can thus be marketed year *** breeding approaches are protracted and labor intensive,and therefore marker-assisted selection(MAS)is a valuable tool for *** advance MAS for storage disorders in apple,we used genotyping-by-sequencing(GBS)to generate high-density genetic maps in two f1 apple populations,which were then used for quantitative trait locus(QTL)mapping of soft *** total,900 million DNA sequence reads were generated,but after several data filtering steps,only 2%of reads were ultimately used to create two genetic maps that included 1918 and 2818 single-nucleotide *** QTL associated with soft scald were identified in one of the bi-parental populations originating from parent 11W-12-11,an advanced breeding *** study demonstrates the utility of next-generation DNA sequencing technologies for QTL mapping in f1 populations,and provides a basis for the advancement of MAS to improve storability of apples.

关键词： breeding cultivar apple

Control Groups: Not Truly Baseline

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World Journal of Neuroscience 2014年第4期4卷 319-325页

作者： Tsee Leng Choy john f. Connolly McMaster Integrative Neuroscience Discovery and Study (MiNDS) McMaster University Hamilton Canada

Although routinely used, control group criteria vary considerably in research. Drawing from aspects in our normative study on musical emotion perception, we show how a group of participants who would normally be considered a control group in most studies, display clear event-related potential (ERP) differences when grouped by affective assessment scores that are rarely administered to presumed “control” group candidates. This preliminary finding demonstrates the importance of careful screening of control group membership. failure in this process can produce misleading observations, undermining the validity of results.

关键词： Event-Related Potentials ERPs Emotion Music Alexithymia Depression Sampling Bias

Consequences of Helicobacter pylori infection in children

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World Journal of Gastroenterology 2010年第41期16卷 5181-5194页

作者： Lucia Pacifico Caterina Anania john f Osborn flavia ferraro Claudio Chiesa Department of Pediatrics Sapienza University of Rome 324 I-00161 Rome Italy Department of Public Health Sciences Sapienza University of Rome I-00185 Rome Italy Department of Molecular Medicine National Research Council I-00133 Rome Italy

Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the hu-man stomach for many decades without adverse con-sequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae.

关键词： Helicobacter pylori Children Gastrointestinal diseases Epigastric pain Anemia Growth retardation Chronic idiopathic thrombocytopenic pupura

Infection Prevalence of <i>Borrelia burgdorferi</i>in Ticks Collected from Songbirds in far-Western Canada

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Open Journal of Animal Sciences 2015年第3期5卷 232-241页

作者： john D. Scott Lance A. Durden john f. Anderson Research Division Lyme Ontario Fergus Ontario Canada Department of Biology Georgia Southern University Statesboro GA USA Department of Entomology and Center for Vector Ecology and Zoonotic Diseases The Connecticut Agricultural Experiment Station New Haven CT USA

Worldwide, wild birds play a vital role in the dispersal of ticks that harbour tick-borne pathogens, including Borrelia burgdorferi, the Lyme disease bacterium. Using PCR testing, we found 124 (31%) of 405 ticks (4 species), which were collected from 21 species of birds in far-western Canada, to be infected with B. burgdorferi. Transstadial transmission of B. burgdorferi occurred from larva to nymph, plus nymph to adult, in the avian coastal tick, Ixodes auritulus, collected from songbirds in British Columbia (B.C). Collectively, all 3 motile life stages (larva, nymph, adult) of this tick had an infection prevalence of 31% for B. burgdorferi, which suggests vector competency. A Pacific Wren was highly infested with I. auritulus immatures, and 20 (44%) of 45 ticks (2 nymphs, 43 larvae) were infected with B. burgdorferi. This heavy infestation shows the high potential to initiate a new population of ticks and to disseminate Lyme spirochetes. Epidemiologically, B. burgdorferi-infected I. auritulus larvae collected from the Spotted Towhee, Swainson’s Thrush, Pacific Wren, and fox Sparrow suggest that these avian hosts act as reservoirs for B. burgdorferi. In this study, the western blacklegged tick, Ixodes pacificus, and Ixodes spinipalpis played a limited role in the enzootic transmission cycle of B. burgdorferi along coastal B.C. We document the first record of I. spinipalpis on a bird in Alberta. Because songbirds widely disperse Lyme disease vector ticks, primary health providers and the general public must be vigilant that outdoors people may be bitten by B. burgdorferi-infected ticks throughout far-western Canada.

关键词： Ticks Ixodes auritulus Ixodes pacificus Ixodes spinipalpis Lyme Disease Borrelia burgdorferi Songbird Bird Parasitism Infection Prevalence