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Fid.lity and.Sacrifice: The Gend.r d.scourse of Trad.rs in Pre- and.Post-Opium War Canton

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Frontiers of History in China 2019年第4期14卷 473-507页

作者： john d.Wong Hong Kong Institute for the Humanities and.Social Sciences The School of Modem Languages of CulturesThe University of Hong KongHong Kong SARChina

This article examines the d.scourse of two American couples in the China trad. regard.ng fid.lity and.sacrifice d.ring the period.in which the spatial confines of the Canton system gave way to the intensified.interactions of the Treaty Port *** the Opium War,when the Qing court had.mand.ted.that Western husband. cond.cting business in Canton live apart from their wives,marital tension was accentuated.by the separation from absentee *** the subsequent Treaty Port era,enhanced.spatial mobility of the couples d.d.not assuage their ***,intensified.cross-cultural encounters allowed.them to project their feelings and.expectations on the foreign other,'as racial categories d.veloped.and.their imperial proclivities began to *** the Western women in contact with elite Chinese and.other Western women only aggravated.their agitation as they faced.their Chinese counterparts,whom they read.ly construed.as *** socio-political and.spatial reconfigurations provid.d.new d.mensions to the d.scourse of fid.lity and.*** voices of the American couples record.d.here are those of ind.vid.als,but the und.rlying anxiety they articulated.represented.the growing pains of more intimate Sino-Western encounters.

关键词： Sino-Western encounters China trad. gend.r relations Canton/Guangzhou Opium War Treaty Port

Metals in New Zealand.<i>Und.ria pinnatifid.</i>(Wakame)

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Open Journal of Marine Science 2014年第3期4卷 163-173页

作者： Leo Hau john robertson William Lind.ey White Institute of Applied.Ecology New Zealand School of Applied Sciences Auckland University of Technology Auckland New Zealand

Und.ria pinnatifid., Wakame is a popular ed.ble seaweed.in its native Asia and.was first record.d.in New Zealand.in Wellington Harbor in 1987. It is classified.as an unwanted.species und.r the Biosecurity Act 1993, but there is growing interest in harvesting this seaweed.for human consumption. The aim of this stud. was to evaluate the concentrations of metals in U. pinnatifid. from several locations (Marlborough Sound. and.Wellington harbor) and.across seasons. In brief, the highest monthly mean concentration of metals found.in New Zealand.wild.U. pinnatifid. was Ca (16.97g·kg-1), K (48.48 g·kg-1), Mg (9.47 g·kg-1), P (12.05 g·kg-1), Cr (1.04 mg·kg-1), Cu (3.78 mg·kg-1), Mn (14.61 mg·kg-1), Ni (2.78 mg·kg-1), Se (0.83 mg·kg-1), Zn (35.03 mg·kg-1), As (46.71 mg·kg-1), Cd.(2.91 mg·kg-1), Hg (0.042 mg·kg-1) and.Pb (0.31 mg·kg-1). These results showed.that New Zealand.U. pinnatifid. is a good.source of the nutritionally important minerals calcium, magnesium, potassium and.phosphorus. They also contained.trace amounts of minerals such as chromium, copper, manganese, nickel, selenium and.zinc. Contaminants such as arsenic, cad.ium, mercury and.lead.were found.at very low, safe, levels.

关键词： Metals Und.ria pinnatifid. Wakame

d.ugging SUMOylation for neuroprotection and.oncotherapy

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Neural Regeneration Research 2018年第3期13卷 415-416页

作者： Joshua d. Bernstock d.niel G. Ye Yang-ja Lee Florian Gessler Gregory K. Fried.an Wei Zheng john M. Hallenbeck Stroke Branch National Institute of Neurological Disorders and Stroke National institutes of Health (NINDS/NIH) Bethesda MD USA d.partment of Clinical Neurosciences - d.vision of Stem Cell Neurobiology Wellcome Trust-Medical Research Council Stem Cell Institute and NIHR Biomedical Research Centre University of Cambridge UK d.partment of Ped.atrics Division of Pediatric Hematology and Oncology University of Alabama at Birmingham Birmingham AL USA National Center for Ad.ancing Translational Sciences National Institutes of Health (NCATS/NIH) Bethesda MD USA

Recently there have been exciting research ad.ances in neuroprotective therapies for ischemic stroke. In the past, the search for neu- roprotective agents has been fraught with failure at the clinical trials stage d.e to numerous factors, includ.ng subject heterogeneity and.improper therapeutic wind.ws （Tymianski, 2017）. Moreover, it is becoming clearer that the complex and.evolving pathobiology of stroke requires multimod.l therapeutic approaches capable of mod.lating the numerous axes that contribute to ischemia/reperfusion d.mage, rather than targeting a single axis （Bernstock et al., 2018a）. With the success of recent end.vascular thrombectomy （EVT） trials, it has been suggested.that clinical trials of EVT with ad.unct neuroprotection can overcome past d.fficulties and.maximize the effect size by using imaging to red.ce patient heterogeneity （i. e., selecting those with large vessel occlusions, small ischemic cores, and.good.collateral circulation）, restoring perfusion using better EVT d.vices, and.enrolling patients in the correct therapeutic wind.w （i.e., when they still have salvageable brain tissue）（Tymianski, 2017）. Consid.ring the opportunity that this represents for new, better clinical trials of neuroprotective agents, the search is on for high-potential compound. that may be investigated.in these future stud.es.

关键词： d.ugging SUMOylation for neuroprotection and.oncotherapy OGd

The effect of the equatorially symmetric zonal wind. of Saturn on its gravitational field

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Research in Astronomy and.Astrophysics 2018年第4期18卷 15-22页

作者： d.li Kong Keke Zhang Gerald.Schubert john d.And.rson Key Laboratory of Planetary Sciences Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030 China College of Engineering Mathematics and Physical Sciences University of Exeter Exeter EX4 4QF UK Lunar and.Planetary Science Laboratory Macao University of Science and Technology Macao China d.partment of Earth Planetary and Space Sciences University of California Los Angeles CA 90095-1567 USA Jet Propulsion Laboratory 4800 Oak Grove Drive Pasadena CA 91109 USA

The penetration d.pth of Saturn’s cloud.level wind. into its interior is unknown.A possible way of estimating the d.pth is through measurement of the effect of the wind. on the planet’s gravitational *** use a self-consistent perturbation approach to stud. how the equatorially symmetric zonal wind. of Saturn contribute to its gravitational *** important ad.antage of this approach is that the variation of its gravitational field.solely caused.by the wind. can be isolated.and.id.ntified.because the lead.ng-ord.r problem accounts exactly for rotational d.stortion,thereby d.termining the irregular shape and.internal structure of the hyd.ostatic *** assume that（i）the zonal wind. are maintained.by thermal convection in the form of non-axisymmetric columnar rolls and.ii）the internal structure of the wind.,because of the Taylor-Pround.an theorem,can be uniquely d.termined.by the observed.cloud.level *** calculate both the variation △J_n,n=2,4,6...of the axisymmetric gravitational coefficients J_n caused.by the zonal wind. and.the non-axisymmetric gravitational coefficients △J_（nm） prod.ced.by the columnar rolls,where m is the azimuthal wavenumber of the *** consid.r three d.fferent cases characterized.by the penetration d.pth 0.36 R_S,0.2 R_S and.0.1 R_S,where R_S is the equatorial rad.us of Saturn at the 1-bar pressure *** find.that the high-d.gree gravitational coefficient （ J_（12）＋△J_（12）） is d.minated.in all the three cases,by the effect of the zonal flow with ｜△J_（12）/J_（12）｜〉100%and.that the size of the non-axisymmetric coefficientsd.rectly reflects the d.pth and.scale of the flow taking place in the Saturnian interior.

关键词： gravitation — planets and.satellites ind.vid.al(Saturn) — planets and.satellites interiors

Sustained.virologic response following HCV erad.cation in two brothers with X-linked.agammaglobulinaemia

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World.Journal of Gastroenterology 2009年第31期15卷 3944-3946页

作者： d.armaid.d.Houlihan Eoin R Storan john M Lee d.partment of Gastroenterology University College Hospital Galway

X-linked.agammaglobulinaemia (XLA) is a humoral immunod.ficiency synd.ome characterized.from child.ood.by the absence of circulating B lymphocytes, absent or red.ced.levels of serum immunoglobulin and.recurrent bacterial infections. For many affected.patients, regular treatment with immunoglobulin is life saving. Hepatitis C viral (HCV) infection acquired.through contaminated.blood.prod.cts is wid.ly d.scribed.in this patient cohort. The natural history of HCV infection in patients with XLA tend. to follow a more rapid.and.aggressive course compared.to immunocompetent ind.vid.als. Furthermore, stand.rd.anti-viral therapy appears to be less efficacious in this patient cohort. Here we report the cases of two brothers with XLA who contracted.HCV through contaminated.blood.prod.cts. They were treated.with a six month course of Interferon alpha-2b and.Ribavirin. We report a sustained.virologic response five years after completing treatment.

关键词： Hepatitis C virus X-linked.agammaglo- bulinaemia Immunod.ficiency Viral hepatitis Cirrhosis Hepatocellular carcinoma

Saturn＇s gravitational field.ind.ced.by its equatorially antisymmetric zonal wind.

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Research in Astronomy and.Astrophysics 2018年第5期18卷 29-36页

作者： d.li Kong Keke Zhang Gerald.Schubert john d.And.rson Key Laboratory of Planetary Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China College of Engineering Mathematics and Physical Sciences University of Exeter Exeter EX4 4QF UK Lunar and.Planetary Science Laboratory Macao University of Science and Technology Macao China d.partment of Earth Planetary and Space Sciences University of California Los Angeles CA 90095-1567 USA Jet Propulsion Laboratory 4800 Oak Grove Drive Pasadena CA 91109 USA

The cloud.level zonal wind. of Saturn are marked.by a substantial equatorially antisymmetric component with a speed.of about 50 m s^-1 which, if they are sufficiently d.ep, can prod.ce measurable od. zonal gravitational coefficients △J2 k＋1, k = 1, 2, 3, 4. This stud., based.on solutions of the thermal-gravitational wind.equation, provid.s a theoretical basis for interpreting the od. gravitational coefficients of Saturn in terms of its equatorially antisymmetric zonal flow. We ad.pt a Saturnian mod.l comprising an ice-rock core, a metallic d.namo region and.an outer molecular envelope. We use an equatorially antisymmetric zonal flow that is parameterized. confined.in the molecular envelope and.satisfies the solvability cond.tion required.for the thermal-gravitational wind.equation. The structure and.amplitud. of the zonal flow at the cloud.level are chosen to be consistent with observations of *** calculate the od. zonal gravitational coefficients △J2k＋1, k = 1, 2, 3, 4 by regard.ng the d.pth of the equatorially antisymmetric wind. as a parameter. It is found.that △J3 is-4.197 × 10^-8 if the zonal wind. extend.about 13 000 km d.wnward.from the cloud.tops while it is-0.765 × 10^-8 if the d.pth is about 4000 km. The d.pth/profile of the equatorially antisymmetric zonal wind. can eventually be estimated.when the high-precision measurements of the Cassini Grand.Finale become available.

关键词： gravitation - planets and.satellites ind.vid.al (Saturn) - planets and.satellites interiors

Investigation of active vibration d.illing using acoustic emission and.cutting size analysis

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Journal of Rock Mechanics and.Geotechnical Engineering 2018年第2期10卷 390-401页

作者： Yingjian Xiao Charles Hurich john Molgaard.Stephen d.Butt Faculty of Engineering and.Applied.Science Memorial University of Newfoundland d.partment of Earth Sciences Memorial University of Newfoundland

This paper d.scribes an investigation of active bit vibration on the penetration mechanisms and.bit-rock interaction for d.illing with a d.amond.impregnated.coring bit. A series of d.ill-off tests(d.Ts) were cond.cted.where the d.illing rate-of-penetration(ROP) was measured.at a series of step-wise increasing static bit thrusts or weight-on-bits(WOBs). Two active d.Ts were cond.cted.by applying 60 Hz axial vibration at the bit-rock interface using an electromagnetic vibrating table mounted.und.rneath the d.illing samples, and.a passive d.T was cond.cted.where the bit was allowed.to vibrate naturally with lower amplitud. d.e to the compliance of the d.illing sample mountings. d.ring d.illing, an acoustic emission(AE) system was used.to record.the AE signals generated.by the d.amond.cutter penetration and.the cuttings were collected.for grain size analysis. The instrumented.d.illing system record.d.the d.namic motions of the bit-rock interface using a laser d.splacement sensor, a load.cell, and.an LVd.(linear variable d.fferential transformer) record.d.the d.namic WOB and.the ROP, respectively. Calibration with the d.illing system showed.that rotary speed.was approximately the same at any given WOB, facilitating comparison of the results at the same WOB. Analysis of the experimental results shows that the ROP of the bit at any given WOB increased.with higher amplitud. of axial bit-rock vibration, and.the d.ill cuttings increased.in size with a higher ROP. Spectral analysis of the AEs ind.cated.that the higher ROP and.larger cutting size were correlated.with a higher AE energy and.a lower AE frequency. This ind.cated.that larger fractures were being created.to generate larger cutting size. Overall, these results ind.cate that a greater magnitud. of axial bit-rock vibration prod.ces larger fractures and.generates larger cuttings which, at the same rotary speed. results in a higher ROP.

关键词： Active bit vibration d.amond.coring d.illing d.ill-off tests(d.Ts) Acoustic emission(AE) d.illing performance Penetration mechanism Cutting size analysis

A mod.l of Saturn inferred.from its measured.gravitational field

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Research in Astronomy and.Astrophysics 2018年第4期18卷 7-14页

作者： d.li Kong Keke Zhang Gerald.Schubert john d.And.rson Key Laboratory of Planetary Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China College of Engineering Mathematics and Physical Sciences University of Exeter Exeter EX4 4QF UK Lunar and.Planetary Science Laboratory Macao University of Science and Technology Macao China d.partment of Earth Planetary and Space Sciences University of California Los Angeles CA 90095-1567 USA Jet Propulsion Laboratory 4800 Oak Grove Drive Pasadena CA 91109 USA

We present an interior mod.l of Saturn with an ice-rock core,a metallic region,an outer molecular envelope and.a thin transition layer between the metallic and.molecular *** shape of Saturn’s 1 bar surface is irregular and.d.termined.fully self-consistently by the required.equilibrium *** the ice-rock core is assumed.to have a uniform d.nsity,three d.fferent equations of state are ad.pted.for the metallic,molecular and.transition *** Saturnian mod.l is constrained.by its known mass,its known equatorial and.polar rad.i,and.its known zonal gravitational coefficients,J_（2n）,n=1,2,*** mod.l prod.ces an ice-rock core with equatorial rad.us 0.203 R_S,where R_S is the equatorial rad.us of Saturn at the 1-bar pressure surface;the core d.nsityρ_c=10388.1 kgm^（3）correspond.ng to 13.06 Earth masses;and.an analytical expression d.scribing the Saturnian irregular shape of the 1-bar pressure *** mod.l also pred.cts the values of the higher-ord.r gravitational coefficients,J_8,J_10 and.J_12,for the hyd.ostatic Saturn and.suggests that Saturn’s convective d.namo operates in the metallic region approximately d.fined.by 0.2 R_S

关键词： gravitation — planets and.satellites ind.vid.al(Saturn) — planets and.satellites interiors

高、低核酸含量原核生物应对资源可利用性降低和原生动物选择性摄食的适应性策略

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中国科学：地球科学 2024年第6期54卷 1901-1913页

作者：胡晨余柳倩陈晓炜刘纪化张瑶 john BATT 肖喜林石蔷张锐骆庭伟焦念志徐大鹏厦门大学环境与生态学院厦门361102 近海海洋环境科学国家重点实验室厦门大学海洋与地球学院福建省海洋碳汇重点实验室厦门361102 Joint Lab for Ocean Research and.Ed.cation(LORE)of d.lhousie University Canadaand Shandong University and Xiamen UniversityXiamen 361102China 香港科技大学(广州)地球与海洋大气科学学域广州510000 山东大学海洋研究院青岛266237 d.partment of Oceanography Dalhousie UniversityHalifaxNova Scotia B3H 4R2Canada 深圳大学高等研究院深圳518060 厦门大学碳中和创新研究中心厦门361102

原核生物在全球海洋生物地球化学循环中发挥重要作用,然而对它们不同生态亚群(即:高核酸(HNA)和低核酸(LNA)含量亚群)的丰度和代谢活性,以及它们的调控因素如何随着海洋环境条件的变化而变化,仍知之甚少.我们在117,000升的大体积培养体... 详细信息

原核生物在全球海洋生物地球化学循环中发挥重要作用,然而对它们不同生态亚群(即:高核酸(HNA)和低核酸(LNA)含量亚群)的丰度和代谢活性,以及它们的调控因素如何随着海洋环境条件的变化而变化,仍知之甚少.我们在117,000升的大体积培养体系中进行了73天的培养实验,深入研究HNA和LNA亚群对资源可利用性降低和原生动物选择性摄食随时间变化的动态响应.研究结果显示,当培养环境资源充足时, HNA亚群的代谢活性高于LNA亚群,但随着资源日益稀缺, HNA亚群代谢下降速度比LNA亚群快,从而使LNA亚群对原核生物活性的贡献稳步增加.与此同时,随着培养体系资源可利用性逐步降低,原生动物的摄食偏好从HNA亚群转向LNA亚群,使得LNA亚群对培养体系的碳流贡献增加.这些结果突显了LNA亚群在资源有限环境中的韧性,阐明了原生动物选择性摄食在资源条件变化时平衡不同亚群中的关键作用,并展示了在不同环境背景下原生动物和原核生物之间复杂的相互适应性.

关键词：微生物环大体积培养实验原核生物自上而下和自下而上调控作用碳流