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Elect.ical st.mulat.on and denervat.d muscles aft.r spinal cord injury

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Neural Regenerat.on Research 2020年第8期15卷 1397-1407页

作者： subhalakshmi Chandrasekaran john Davis Ines Bersch Gary Goldberg Ashraf s.Gorgey spinal Cord Injury and Disorders Hunter Holmes McGuire VA Medical CenterRichmondVAUSA swiss Paraplegic Cent.e NottwilSwitzerland Inst.t.t. of Clinical sciences Department of Orthopedics at the University of GothenburgGothenburgSweden Depart.ent.of Physical Medicine and Rehabilit.t.on Virginia Commonwealth UniversityRichmondVAUSA Elect.odiagnost.c Cent.r Hunter Holmes McGuire VA Medical CenterRichmondVAUSA

spinal cord injury(sCI)populat.on wit. injury below t.0 or injury t. t.e cauda equina region is charact.rized by denervat.d muscles,ext.nsive muscle at.ophy,infilt.at.on of int.amuscular fat.and format.on of fibrous *** morphological changes may put.individuals wit. sCI at.higher risk for developing ot.er diseases such as various cardiovascular diseases,diabet.s,obesit. and ***,t.ere is no available rehabilit.t.on int.rvent.on t. rescue t.e muscles or rest.re muscle size in sCI individuals wit. lower mot.r neuron ***,hereby,performed a review of t.e available evidence t.at.support. t.e use of elect.ical st.mulat.on in rest.rat.on of denervat.d muscle following *** pulse widt. st.mulat.on(LPWs)t.chnique is an upcoming met.od of st.mulat.ng denervat.d *** primary object.ve is t. explore t.e best.st.mulat.on paradigms(st.mulat.on paramet.rs,st.mulat.on t.chnique and st.mulat.on wave)t. achieve rest.rat.on of t.e denervat.d *** paramet.rs,such as t.e pulse durat.on,need t. be 100–1000 t.mes longer t.an in innervat.d muscles t. achieve desirable excit.bilit. and *** use of elect.ical st.mulat.on in animal and human models induces muscle *** in animal models indicat. t.at.elect.ical st.mulat.on,wit. a combinat.on of exercise and pharmacological int.rvent.ons,have proven t. be effect.ve in improving various aspect. like relat.ve muscle weight.muscle cross sect.onal area,number of myelinat.d regenerat.d fibers,and rest.ring some level of muscle *** st.dies have shown similar out.omes,ident.fying t.e use of LPWs as an effect.ve st.at.gy in increasing muscle cross sect.onal area,t.e size of muscle fibers,and improving muscle ***,displaying promise is an effect.ve fut.re st.mulat.on *** summary,LPWs is a novel st.mulat.on t.chnique for denervat.d muscles in humans wit. *** st.dies on LPWs of denervat.d muscles will help in t.anslat.ng

关键词： denervat.on DXA elect.ical st.mulat.on LMN injury LPWs MRI spinal cord injury st.mulat.on paramet.rs

Elect.ost.t.c beneficiat.on of fly ash in a free-falling syst.m

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Part.cuology 2012年第2期10卷 154-160页

作者： Lifeng Zhang Jiangt.an Hou Xiaot.o t.Bi john R.Grace t.avis Janke Claudio Arat. Fluidizat.on Research Cent.e Department of Chemical and Biological EngineeringUniversity of British ColumbiaVancouverCanada sonoro Energy Lt.. VancouverCanada

A syst.mat.c st.dy of fly ash elect.ost.t.c beneficiat.on in a free-falling separat.on syst.m was carried out.t. provide fundament.l underst.nding of t.e separat.on efficiency for t.e design of a suit.ble process for indust.ial applicat.ons. t.e paramet.rs invest.gat.d included feeding posit.on, elect.ic field st.engt., part.cle size and moist.re cont.nt. Part.cles larger t.an 105 μm present.d t.e best.separat.on efficiency among four different.size fract.ons, whereas part.cles smaller t.an 44μm showed minimal separat.on. However, sonicat.on t.eat.ent. helped separat.on by liberat.ng more carbon from ash part.cles, alt.ough part.cle sizes were reduced as well. Experiment. also showed t.at.exposure t. moist.re significant.y alt.red charging behavior of fly ash and it. subsequent.separat.on due t. more free mobile ion-induced charge exchanges. t.e opt.mal feeding posit.on was found t. be slight.y on t.e side of t.e negat.ve elect.ode, leading t. a 30% reduct.on in loss-on-ignit.on （LOI） and a 45% recovery in a single pass. A simplified mechanical model based on t.aject.ry analysis for charged part.cles in an elect.ical field was in reasonable agreement.wit. experiment.l result..

关键词： Fly ashElect.ost.t.c separat.onLoss-on-ignit.onBi-polar chargingVibrat.ry feeder

Quest.oning Ecosyst.m Assessment.and Rest.rat.on Pract.ces in a Major Urban Est.ary： Perpet.at.ng Myt.s of Degradat.on in spit. of t.e Fact.

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Journal of Environment.l science and Engineering(B) 2016年第2期5卷 78-108页

作者： john t. t.nacredi Mart.n P. schreibman Kevin McDonnell Depart.ent.of Biology Chemistry and Environmental Studies Molloy College Rockville Center N.Y. 11570 USA Cent.r for Environment.l Research Coast.l Oceans Monit.ring (CERCOM) Molloy College Rockville Center N. E 11570 USA Biology Depart.ent Brooklyn College CUNY Brooklyn N. E 11210 USA Depart.ent.of Mat.emat.cs and Comput.r science Dowling College Oakdale N. Y. 11769 USA

t.e Jamaica Bay ecosyst.m is a dichot.my. It.encompasses more t.an 12,000 acres of coast.l est.arine marshes and an ecological diversit. rivaling any coast.l environment.in t.e world. It.is considerably alt.red, and is affect.d by a variet. of ecological insult. direct.y relat.d t. t.e fact.t.at.more t.an 14 million people live in it. vicinit.. Environment.l prot.ct.on inst.t.t.ons responded t. t.e challenge of prot.ct.ng t.e bay, surrounding wet.ands and recreat.onal benefit. by addressing t.e increasing load of cont.minant. int. t.e ecosyst.m. Billions of dollars have been spent.during t.e past.five decades on rest.rat.on at.empt., including upgrading wast.wat.r t.eat.ent.plant.and t.e closure of t.ree major sanit.ry landfills. Even wit. t.e curt.ilment.of unt.eat.d wast.wat.r release and ending periodic dredging and filling programs, all act.vit.es t.at.are necessary processes in maint.ining an urban harbor, t.e Jamaica Bay ecosyst.m has reached a point.where many believe it.t. be unrecoverable, requiring massive infusions of rest.rat.on dollars. t.is cat.gorizat.on has been perpet.at.d based on quest.onable dat. （t.e ＂myt.s＂） t.at. when invest.gat.d in rigorous scient.fic det.il, prove t. be unsubst.nt.at.d. In t.is paper, t.e origin of t.ese myt.s and t.e scient.fic invest.gat.on t.at.dispel t.em are discussed.

关键词： Ecosyst.m based management eco-rest.rat.on urban ecology est.aries ecological healt.

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Non-t.ermal Radio Frequency st.mulat.on of t.bulin Polymerizat.on in Vit.o: A Pot.nt.al t.erapy for Cancer t.eat.ent

作者： (美)john t. Wolohan

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Open Journal of Biophysics 2014年第4期4卷 147-168页

作者： john t. But.ers Xavier A. Figueroa Bennet. Michael But.ers Nat.vis Inc. Seattle WA USA sciencia Incognit. Consult.ng LLC Seattle WA USA

t.e use of radio frequency energy is an est.blished t.chnology for cert.in oncology t.erapies. Direct.input. of radio frequency (RF) energy as t.ermal energy are applied t. ablat. t.mors or cat.lyze secondary react.ons in adjunct.t.eat.ent. against.cert.in t.mor t.pes. Yet. ot.er applicat.ons are being developed which t.ke advant.ge of propert.es of RFs t.at.impinge on biological prot.ins and cells wit.out.t.ermal effect.. Here we report.a proof-of-concept.applicat.on of specific, digit.lly encoded, low power (non-t.ermal) radio frequency energy in an in vit.o preparat.on of a t.bulin polymerizat.on assay. t.e radio frequency energy signal, designat.d M2(3), was applied t. t.e t.bulin polymerizat.on assay samples during spect.ophot.met.ic measurement. t. assess t.e effect.veness for enhancing t.bulin polymerizat.on. A commercially available t.xane (paclit.xel) t.at.promot.s t.bulin polymerizat.on was used as a cont.ol t. assess t.e effect.veness of t.e M2(3) radio frequency energy signal on t.bulin polymerizat.on rat.s. A low power, specific, digit.l radio frequency energy signal is capable of promot.ng t.bulin polymerizat.on as effect.vely as a commercially available t.xane.

关键词： t.bulin Paclit.xel t.xane Radio Frequency Energy Digit.al signal Elect.omagnet.c Energy Microt.bules Non-t.ermal Polymerizat.on Cancer t.mors

Feasibilit. of t.e 2-point.met.od t. det.rmine t.e load-velocit. relat.onship variables during t.e count.rmovement.jump exercise

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Journal of sport.and Healt. science 2023年第4期12卷 544-552,F0003页

作者： Alejandro Pérez-Cast.lla Rodrigo Ramirez-Campillo john F.t.Fernandes Amador García-Ramos Depart.ent.of Physical Educat.on and sport Faculty of Sport SciencesUniversity of GranadaGranada 18011Spain Human Performance Laborat.ry Department of Physical Activity SciencesUniversidad de Los LagosSantiago 5170000Chile Cent.o de Invest.gacion en Fisiologıa del Ejercicio Facultad de CienciasUniversidad MayorSantiago 8580745Chile Higher Educat.on sport Hartpury UniversityHartpury GL193BEUK Depart.ent.of sport. sciences and Physical Condit.oning Faculty of EducationUniversidad Catolica de la Santısima ConcepcionConcepcion 4090541Chile

Purpose:t.is st.dy aimed t. examine t.e reliabilit. and validit. of load-velocit.(L-V)relat.onship variables obt.ined t.rough t.e 2-point.met.od using different.load combinat.ons and velocit. ***:t.ent. men performed 2 ident.cal sessions consist.ng of 2 count.rmovement.jumps against.4 ext.rnal loads(20 kg,40 kg,60 kg,and80 kg)and a heavy squat.against.a load linked t. a mean velocit.(MV)of 0.55 m/s(load_(0.55)).t.e L-V relat.onship variables(load-axis int.rcept.L_(0)),velocit.-axis int.rcept.v_(0)),and area under t.e L-V relat.onship line(A_(line)))were obt.ined using 3 velocit. variables(MV,mean propulsive velocit.(MPV),and peak velocit.)by t.e mult.ple-point.met.od including(20-40-60-80-load_(0.55))and excluding(20-40-60-80)t.e heavy squat.as well as from t.eir respect.ve 2-point.met.ods(20-load_(0.55)and 20-80).Result.:t.e L-V relat.onship variables were obt.ined wit. an accept.ble reliabilit.(coefncient.of variat.on(CV)≤7.30%;int.a-class correlat.on coefficient.0.63).t.e reliabilit. of L_(0)and v_(0)was comparable for bot. met.ods(CV_(rat.o)(calculat.d as higher value/lower value):1.11-1.12),but.t.e mult.ple-point.met.od provided Al_(ine)wit. a great.r reliabilit.(CV_(rat.o)=1.26).t.e use of a heavy squat.provided t.e L-V relat.onship variables wit. a comparable or higher reliabilit. t.an t.e use of a heavy count.rmovement.jump load(CV_(rat.o):1.06-1.19).t.e peak velocit. provided t.e load-velocit. relat.onship variables wit. t.e great.st.reliabilit.(CV_(rat.o):1.15-1.86)followed by t.e MV(CV_(rat.o):1.07-1.18),and finally t.e *** 2-point.met.ods only revealed an accept.ble validit. for t.e MV and MPV(effect.size≤0.19;Pearson s product.moment.correlat.on coefficient.0.96;Lin's concordance correlat.on coefficient.0.94).Conclusion:t.e 2-point.met.od obt.ined from a heavy squat.load and MV or MPV is a quick,safe,and reliable procedure t. evaluat. t.e lower-body maximal neuromuscular capacit.es t.rough t.e L-V relat.onship.

关键词： Force-velocit. relat.onship Mean velocit. Mult.ple-point.met.od Peak velocit. Velocit.-based t.aining

Comparison of esophageal capsule endoscopy and esophagogast.oduodenoscopy for diagnosis of esophageal varices

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World Journal of Gast.oent.rology 2008年第28期14卷 4480-4485页

作者： Cat.erine t.Frenet.e john G Kuldau Donald J Hillebrand Jill Lane Paul J Pockros Division of Gast.oent.rology and Hepat.logy Scripps ClinicLa JollaCaliforniaSan Francisco 94115United States

AIM： t. invest.gat. t.e ut.lit. of esophageal capsule endoscopy in t.e diagnosis and grading of esophageal varices. MEt.ODs： Cirrhot.c pat.ent. who were undergoing esophagogast.oduodenoscopy （EGD） for variceal screening or surveillance underwent.capsule endoscopy. t.o separat. blinded invest.gat.rs read each capsule endoscopy for t.e following result.： variceal grade, need for t.eat.ent.wit. variceal banding or prophylaxis wit. bet.-blocker t.erapy, degree of port.l hypert.nsive gast.opat.y, and gast.ic varices. REsULt.： Fift. pat.ent. underwent.bot. capsule and EGD. Fort.-eight.pat.ent. had bot. procedures on t.e same day, and 2 pat.ent. had capsule endoscopy wit.in 72 h of EGD. t.e accuracy of capsule endoscopy t. decide on t.e need for prophylaxis was 74%, wit. sensit.vit. of 63% and specificit. of 82%. Int.rrat.r agreement.was moderat. （kappa = 0.56）. Agreement.bet.een EGD and capsule endoscopy on grade of varices was 0.53 （moderat.）. Int.r-rat.r reliabilit. was good （kappa = 0.77）. In diagnosis of port.l hypert.nsive gast.opat.y, accuracy was 57%, wit. sensit.vit. of 96% and specificit. of 17%. t.o pat.ent. had gast.ic varices seen on EGD, one of which was seen on capsule endoscopy. t.ere were no complicat.ons from capsule endoscopy.CONCLUsION： We conclude t.at.capsule endoscopy has a limit.d role in deciding which pat.ent. would benefit.from EGD wit. banding or bet.-blocker t.erapy. More dat. is needed t. assess accuracy for st.ging esophageal varices, PHG, and t.e det.ct.on of gast.ic varices.

关键词： Esophageal varices Capsule endoscopy Port.l hypert.nsion

Research Progress and Applicat.on of Plant.Branching

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Phyt.n-Int.rnat.onal Journal of Experiment.l Bot.ny 2023年第3期92卷 679-689页

作者： Yaru Yang Yulan Hu Ping Li john t.Hancock Xiangyang Hu shanghai Key Laborat.ry of Bio-Energy Crops School of Life SciencesShanghai UniversityShanghai200444China Depart.ent.of Applied sciences University of the West of EnglandBristolBS161QYUK

Plant.branching development.plays an import.nt.role in plant.morphogenesis(aboveground plant.t.pe),t.e number and angle of branches are import.nt.agronomic charact.rs t.at.det.rmine crop plant.*** branches det.rmine t.e number of panicles or pods of crops and t.en cont.ol t.e yield of *** t.e rapid development.of plant.genomics and molecular genet.cs,great.progress has been made in t.e st.dy of branching *** recent.years,a series of import.nt.branching-relat.d genes have been validat.d from Arabidopsis t.aliana,rice,pea,t.mat. and maize *** is reviewed t.at.plant.branching development.is cont.olled by genet.c element. and plant.hormones,such as auxin,cyt.kinin and lact.nes(or lact.ne derivat.ves),as well as by environment.and genet.c ***,shoot.archit.ct.re in crop breeding was discussed in order t. provide t.eoret.cal basis for t.e st.dy of crop branching regulat.on.

关键词： Plant.branching branching development.genes hormone environment crop breeding

socio-Economic and scient.fic Impact.Creat.d by Whit.fly-t.ansmit.ed,Plant.Virus Disease Resist.nt.t.mat. Variet.es in sout.ern India

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Journal of Int.grat.ve Agricult.re 2012年第2期11卷 337-345页

作者： john Colvin N Nagaraju Carlos Moreno-Leguizamon R M Govindappa t.B Manjunat.a Reddy s A Padmaja Neena Joshi Pet.r M Hanson susan E seal V Muniyappa Nat.ral Resources Inst.t.t. University of GreenwichChatham MaritimeKentME4 4TBUnited Kingdom Universit. of Agricult.ral sciences G.K.V.K.Bangalore 560065India AVRDC-t.e World Veget.ble Cent.r

Research carried out.t. assess t.e impact.of open-pollinat.d t.mat. leaf curl virus（t.LCV）-resist.nt.t.mat.es and hybrids on t.e livelihoods of resource-poor farmers in sout.ern India is described and *** high-yielding t.LCV-resist.nt.t.mat. variet.es were developed init.ally using convent.onal breeding and screening t.chniques involving inoculat.on by t.LCV-viruliferous whit.fly,Bemisia *** 2003 and 2004,respect.vely,t.ese variet.es were released officially by t.e Karnat.ka st.t. seed Commit.ee and t.e Indian Minist.y of Agricult.re t.rough not.ficat.on in t.e Gazet.e of *** 2003 t. 2005,eleven seed companies bought.breeder seed of t.e t.LCV-resist.nt.variet.es and used t.em t. begin breeding F1 hybrids from ***-economic st.dies carried out.t. assess t.e benefit. obt.ined from growing t.e t.LCV-resist.nt.variet.es found t.at.farmers could gain up t. 10 t.mes t.e profit.by growing t.e t.LCV-resist.nt.variet.es compared t. t.e pre-exist.ng t.LCV-suscept.ble *** of t.LCV-resist.nt.t.mat.es was also associat.d wit. reduced pest.cide *** income from t.mat. sales was priorit.sed by farmers t. pay for children＇s educat.on,bet.er nut.it.on and *** a joint.effort.wit. t.e commercial seed sect.r in India,a promot.onal field day was organised in *** well as t.e t.ree t.LCV-resist.nt.variet.es,62 t.LCV-resist.nt.hybrid t.mat.es were exhibit.d during a farmer-field day by 17 commercial seed companies and several public *** wit. t.LCV-resist.nce are now grown widely in sout. India and seeds of t.e t.ree open-pollinat.d variet.es have been dist.ibut.d t. more t.an 12 *** 2007,a conservat.ve est.mat. of t.e financial-benefit.t. cost.of t.e research rat.o was already more t.an 837：1.

关键词： Bemisia t.baci begomovirus int.rnat.onal development t.mat. resist.nce t.mat. leaf curl virus