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青藏高原东南缘三维S波速度和径向各向异性及泸定M_(S)6.8和芦山M_(S)7.0地震孕震环境探讨

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地球物理学报 2024年第1期67卷 108-127页

作者：孙回归王兴臣常利军中国地震局地球物理研究所北京100081 中国地震局震源物理重点实验室北京100081

利用青藏高原东南缘布设的684个流动地震台和150个固定地震台的连续背景噪声波形数据,提取了周期5~50 s的Rayleigh波和Love波相速度频散,并反演获得了该区域下方0~70 km三维S波速度和径向各向异性结构.结果表明:(1)受川滇地块南部高速... 详细信息

利用青藏高原东南缘布设的684个流动地震台和150个固定地震台的连续背景噪声波形数据,提取了周期5~50 s的Rayleigh波和Love波相速度频散,并反演获得了该区域下方0~70 km三维S波速度和径向各向异性结构.结果表明:(1)受川滇地块南部高速体的阻挡,东南缘中下地壳内存在两条空间分布独立的低速带.西侧(L1)从川滇地块北部向南延伸至滇西南地块,其中下地壳平均V_(S)小于3.4 km·s^(-1)并表现为正径向各向异性结构,反映了高原中下地壳可能存在部分熔融和韧性变形;东侧低速带(L2)沿着小江断层南北分布,受到红河断层的阻挡,弱物质不太可能进入滇西南地块,该区域下地壳和上地幔顶部均显示较强的正各向异性,推测其更可能是沿小江断层相互驱动的块体在横向挤压过程中引起的地壳部分熔融而导致.(2)芦山M_(S)7.0地震位于龙门山逆冲断层南段,泸定M_(S)6.8地震位于鲜水河走滑断层东南段,两者都发生在地壳浅层高低速异常过渡带上,但其深部孕震环境有所不同.芦山震区西北部中下地壳低速体为负各向异性,推测韧性物质沿着龙门山下方陡倾断层向上运移,上地壳积累应力并通过薄弱区域释放导致了芦山地震的发生;泸定震区为正各向异性的中下地壳韧性变形促进了川滇地块SE向的水平运动,受刚性的四川盆地阻挡,加剧了上地壳发震断层的滑动变形和应力积累,脆性上地壳突然破裂导致了泸定地震的发生.

关键词：青藏高原东南缘背景噪声成像 S波速度径向各向异性泸定M_(S)6.8地震芦山M_(S)7.0地震

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Low-Cost Federated Broad Learning for Privacy-Preserved Knowledge Sharing in the RIS-Aided Internet of Vehicles

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Engineering 2024年第2期33卷 178-189页

作者： Xiaoming Yuan Jiahui Chen Ning Zhang Qiang(john)Ye changle Li Chunsheng Zhu Xuemin Sherman Shen Qinhuangdao Branch Campus Northeastern UniversityQinhuangdao 066004China State Key Laboratory of Integrated Services Networks&the Research Institute of Smart transportation Xidian UniversityXi’an 710071China Department of Electrical and Computer Engineering University of WindsorWindsorON N9B 3P4Canada Department of Electrical and Software Engineering University of CalgaryCalgaryAB T2N 1N4Canada SUStech Institute of Future Networks Southern University of Science and TechnologyShenzhen 518055China Department of Electrical and Computer Engineering University of WaterlooWaterlooON N2L 3G1Canada

High-efficiency and low-cost knowledge sharing can improve the decision-making ability of autonomous vehicles by mining knowledge from the Internet of Vehicles(IoVs).However,it is challenging to ensure high efficiency of local data learning models while preventing privacy leakage in a high mobility *** order to protect data privacy and improve data learning efficiency in knowledge sharing,we propose an asynchronous federated broad learning(FBL)framework that integrates broad learning(BL)into federated learning(FL).In FBL,we design a broad fully connected model(BFCM)as a local model for training client *** enhance the wireless channel quality for knowledge sharing and reduce the communication and computation cost of participating clients,we construct a joint resource allocation and reconfigurable intelligent surface(RIS)configuration optimization framework for *** problem is decoupled into two convex *** to improve the resource scheduling efficiency in FBL,a double Davidon–Fletcher–Powell(DDFP)algorithm is presented to solve the time slot allocation and RIS configuration *** on the results of resource scheduling,we design a reward-allocation algorithm based on federated incentive learning(FIL)in FBL to compensate clients for their *** simulation results show that the proposed FBL framework achieves better performance than the comparison models in terms of efficiency,accuracy,and cost for knowledge sharing in the IoV.

关键词： Knowledge sharing Internet of Vehicles Federated learning Broad learning Reconfigurable intelligent surfaces Resource allocation

Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 475-492页

作者： Hong-Mei Wu Yuan-Yuan Huang Yu-Qiu Xu Wei-Lai Xiang chang Yang Ru-Yuan Liu Di Li Xue-Feng Guo Zheng-Bao Zhang Chun-Hua Bei Sheng-Kui tan Xiao-Nian Zhu Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health Guilin Medical UniversityGuilin 541199Guangxi Zhuang Autonomous RegionChina

BACKGROUND B56εis a regulatory subunit of the serine/threonine protein phosphatase 2A,which is abnormally expressed in tumors and regulates various tumor cell *** present,the application of B56εin pan-cancer lacks a comprehensive analysis,and its role and mechanism in hepatocellular carcinoma(HCC)are still *** Cancer Genome Atlas,Genotype-tissue Expression,Gene Expression Profiling Interactive Analysis,and tumor Immune Estimation Resource databases were used to analyze B56εexpression,prognostic mutations,somatic copy number alterations,and tumor immune characteristics in 33 *** relationships between B56εexpression levels and drug sensitivity,immuno-therapy,immune checkpoints,and human leukocyte antigen(HLA)-related genes were further *** Set Enrichment Analysis(GSEA)was performed to reveal the role of B56εin *** Cell Counting Kit-8,plate cloning,wound healing,and transwell assays were conducted to assess the effects of B56εinterference on the malignant behavior of HCC *** In most tumors,B56εexpression was upregulated,and high B56εexpression was a risk factor for adrenocortical cancer,HCC,pancreatic adenocarcinoma,and pheochromocytoma and paraganglioma(all Pted with a variety of immune cells,such as t helper 17 cells,B cells,and *** was a positive correlation between B56εexpression levels with immune checkpoint genes and HLA-related genes(all Pthe expression of B56εwas negatively correlated with the sensitivity of most chemotherapy drugs,but a small number showed a positive correlation(all Pthat B56εexpression was related to the cancer pathway,p53 downstream pathway,and interleukin-mediated signaling in *** of B56εexpression in HCC cells inhibited the proliferation,migration,and invasion capacity of tumor *** tip:the expression of protein phosphatase 2A(PP2A)subunit B56εis up-regulated in most tumors,and its high

关键词： B56ε Prognosis tumor microenvironment Immune infiltration Immunotherapy Hepatocellular carcinoma

C+L波段低弯曲损耗非耦合三模组渐变折射率光纤设计

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电子学报 2024年第8期52卷 2659-2667页

作者：王卓崔明杰余长源香港理工大学电机及电子工程学系中国香港999077 香港理工大学光子研究院中国香港999077 香港理工大学深圳研究院广东深圳518057

光纤是现代通信网络中最为稳定的信号传输媒介,提升光纤模式的数量是满足通信容量日益增加的有效方法.本文设计了低弯曲损耗的非耦合三模组(LP_(01),LP_(11),LP_(21))渐变折射率光纤,运用分层分析法给出了渐变折射率光纤中模组的严格截... 详细信息

光纤是现代通信网络中最为稳定的信号传输媒介,提升光纤模式的数量是满足通信容量日益增加的有效方法.本文设计了低弯曲损耗的非耦合三模组(LP_(01),LP_(11),LP_(21))渐变折射率光纤,运用分层分析法给出了渐变折射率光纤中模组的严格截止条件.此外,利用有限元仿真软件求解光纤模式的有效模场面积和弯曲损耗,得到低弯曲损耗条件下在C+L波段(1530~1625 nm)传输三模组的设计区间.揭示了纤芯中心折射率凹陷和沟槽层共同作用可促进光纤径向高阶模式的截止.模拟结果表明,所设计光纤的模组间有效折射率差大于等于3×10^(-3),弯曲半径为30 mm时的最大弯曲损耗为1.3 d B/km,符合ItU-t推荐的低弯曲损耗条件.而且,在1550 nm波长下,模组内简并模有较小的差分模式群时延(≈176 ps/km),可通过4×4多输入多输出技术补偿简并模之间的串扰.该光纤可适用于C+L波段上实现模组间非耦合的空分复用信号传输.

关键词：少模光纤渐变折射率低弯曲损耗空分复用光纤通信

Nonlinear Optical Properties in a Quantum Dot of Some Polar Semiconductors

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Chinese Physics Letters 2013年第10期30卷 147-151页

作者： A.Azhagu Parvathi A.john Peter chang Kyoo Yoo Department of Physics VV Vanniaperumal College for WomenVirudhunagar-626001India Department of Physics Govt.Arts and Science CollegeMelur-625106MaduraiIndia Center for Environmental Studies/Green Energy Center Department of Environmental Science and EngineeringCollege of EngineeringKyung Hee UniversitySeocheon-dong 1Giheung-guYongin-SiGyeonggi-Do 446-701South Korea

Exciton binding energy,interband emission energy,oscillator strength,and some nonlinear optical properties in quantum dots made up of polar semiconductors are computed with the geometrical *** effects of the interaction of charge carriers with the longitudinal optical phonons on the exciton binding energy are *** anisotropy of the effective masses of holes is incorporated throughout the *** optical exciton absorption of Ⅱ–Ⅵ systems based on some polar semiconductors in the presence of LO phonons is *** optical rectification coefficient associated with the intersubband transitions in a quantum dot of polar semiconductors is *** of refractive index with the photon energy in a polar quantum dot are *** results show that the polar bound excitons in Ⅱ–Ⅵ based polar semiconductors depend on the geometrical confinement,and the nonlinear optical properties strongly depend on the polar materials.

关键词： materials Nonlinear semiconductors

Combined AtAC-seq,RNA-seq,and GWAS analysis reveals glycogen metabolism regulatory network in Jinjiang oyster(Crassostrea ariakensis)

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Zoological Research 2024年第1期45卷 201-214页

作者： Biao Wu Xi Chen Jie Hu Zhen-Yuan Wang Yan Wang Da-You Xu Hao-Bing Guo chang-Wei Shao Li-Qing Zhou Xiu-Jun Sun tao Yu Xiao-Mei Wang Yan-Xin Zheng Guang-Yi Fan Zhi-Hong Liu State Key Laboratory of Mariculture Biobreeding and Sustainable Goods Yellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdaoShandong 266071China Laboratory for Marine Fisheries Science and Food Production Processes Laoshan LaboratoryQingdaoShandong 266071China BGI-Qingdao BGI-ShenzhenQingdaoShandong 266426China National Demonstration Center for Experimental Fisheries Science Education Shanghai Ocean UniversityShanghai 201306China changdao Enhancement and Experiment Station Chinese Academy of Fishery SciencesYantaiShandong 265800China State Key Laboratory of Agricultural Genomics BGI-ShenzhenShenzhenGuangdong 518083China

Glycogen serves as the principal energy reserve for metabolic processes in aquatic shellfish and substantially contributes to the flavor and quality of *** Jinjiang oyster(Crassostrea ariakensis)is an economically and ecologically important species in *** the present study,RNA sequencing(RNA-seq)and assay for transposase-accessible chromatin using sequencing(AtAC-seq)were performed to investigate gene expression and chromatin accessibility variations in oysters with different glycogen *** identified 9483 differentially expressed genes(DEGs)and 7215 genes with significantly differential chromatin accessibility(DCAGs)were obtained,with an overlap of 2600 genes between ***,a significant proportion of these genes were enriched in pathways related to glycogen metabolism,including“Glycogen metabolic process”and“Starch and sucrose metabolism”.In addition,genome-wide association study(GWAS)identified 526 single nucleotide polymorphism(SNP)loci associated with glycogen *** loci corresponded to 241 genes,63 of which were categorized as both DEGs and *** study enriches basic research data and provides insights into the molecular mechanisms underlying the regulation of glycogen metabolism in ***.

关键词： Crassostrea ariakensis Glycogen transcriptome AtAC GWAS

Combining GLP-1 receptor agonists and SGLt-2 inhibitors for cardiovascular disease prevention in type 2 diabetes:A systematic review with multiple network meta-regressions

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World Journal of Diabetes 2024年第10期15卷 2135-2146页

作者： Jing-Jing Zhu john P H Wilding Xiao-Song Gu Department of Endocrinology and Metabolic Medicine The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina Department of Cardiovascular and Metabolic Medicine University of LiverpoolLiverpool L697ZXUnited Kingdom Clinical Sciences Centre Liverpool University Hospitals NHS Foundation TrustLiverpool L97ALUnited Kingdom Department of Cardiovascular Medicine The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina

BACKGROUND Glucagon-like peptide-1 receptor agonists(GLP-1RA)and sodium-glucose co-transporter-2 inhibitors(SGLt-2I)are associated with significant cardiovascular benefit in type 2 diabetes(t2D).However,GLP-1RA or SGLt-2I alone may not improve some cardiovascular outcomes in patients with prior cardiovascular *** to explore whether combining GLP-1RA and SGLt-2I can achieve additional benefit in preventing cardiovascular diseases in *** the systematic review was conducted according to PRISMA *** protocol was registered on PROSPERO(ID:42022385007).A total of 107049 participants from eligible cardiovascular outcomes trials of GLP-1RA and SGLt-2I were included in network meta-regressions to estimate cardiovascular benefit of the combination *** modification of prior myocardial infarction(MI)and heart failure(HF)was also explored to provide clinical insight as to when the INtRODUCtION the macro-and micro-vascular benefits of glucagon-like peptide-1 receptor agonists(GLP-1RA)and sodium-glucose co-transporter-2 inhibitors(SGLt-2I)are independent of their glucose-lowering effects[1].In patients with type 2 diabetes(t2D),the major cardiovascular outcome trials(CVOt)showed that dipeptidyl peptidase-4 inhibitors(DPP-4I)did not improve cardiovascular outcomes[2],whereas cardiovascular benefit of GLP-1RA or SGLt-2I was significant[3,4].Further subgroup analyses indicated that the background cardiovascular risk should be considered when examining the cardiovascular outcomes of these newer glucose-lowering *** instance,prevention of major adverse cardiovascular events(MACE)was only seen in those patients with baseline atherosclerotic cardiovascular disease[3,4].Moreover,a series of CVOt conducted in patients with heart failure(HF)have demonstrated that(compared with placebo)SGLt-2I significantly reduced risk of hospitalization for HF or cardiovascular death,irrespective of their history of t2D[5-8].However,similar car

关键词： type 2 diabetes Glucagon-like peptide-1 receptor agonist Sodium-glucose co-transporter-2 inhibitor Combination treatment Cardiovascular outcome Systematic review Network meta-regression

the risk of prostate cancer on incidental finding of an avid prostate uptake on 2-deoxy-2-[^(18)F]fluoro-D-glucose positron emission tomography/computed tomography for non-prostate cancer-related pathology:A single centre retrospective study

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Asian Journal of Urology 2024年第1期11卷 33-41页

作者： Anthony Franklin troy Gianduzzo Boon Kua David Wong Louise McEwan James Walters Rachel Esler Matthew J.Roberts Geoff Coughlina john W.Yaxley Department of Urology The Wesley HospitalBrisbaneQLDAustralia Wesley Medical Research BrisbaneQLDAustralia School of Medicine The University of QueenslandBrisbaneQLDAustralia Department of Radiology Wesley Medical ImagingBrisbaneQLDAustralia Department of Urology Royal Brisbane and Women's HospitalBrisbaneQLDAustralia

Objective:to review the risk of prostate cancer(PCa)in men with incidentally reported increased intraprostatic uptake at 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography(18F-FDG PEt/Ct)ordered at Department of Urology,the Wesley Hospital,Brisbane,QLD,Australia for non-PCa related ***:Retrospective analysis of consecutive men between August 2014 and August 2019 presenting to a single institution for 18F-FDG PEt/Ct for non-prostate related conditions was *** were classified as benign,indeterminate,or malignant depending of the results of prostate-specific antigen(PSA),PSA velocity,biopsy histopathology,and three-tesla(3 t)multiparametric MRI(mpMRI)Prostate Imaging Reporting and Data System score,or gallium-68-prostate-specific membrane antigen(68Ga-PSMA)PEt/Ct ***:three percent(273/9122)of men demonstrated 18F-FDG avidity within the ***-five percent(231/273)were further investigated,including with PSA tests(227/231,98.3%),3 t mpMRI(68/231,29.4%),68Ga-PSMA PEt/Ct(33/231,14.3%),and prostate biopsy(57/231,24.7%).Results were considered benign in 130/231(56.3%),indeterminate in 31/231(13.4%),and malignant in 70/231(30.3%).PCa was identified in 51/57(89.5%)of the men who proceeded to biopsy,including 26/27(96.3%)men with Prostate Imaging Reporting and Data System scores 4-5 mpMRI and six men with a positive 68Ga-PSMA PEt/*** most common Gleason score on biopsy was greater than or equal to 4+5(14/51,27.5%).68Ga-PSMA PEt/Ct was concordant with the 18F-FDG findings in 26/33(78.8%).All 13 men with a positive concordant 18F-FDG,3 t mpMRI,and 68Ga-PSMA PEt/Ct had PCa on *** was no statistically significant difference in the 18F-FDG maximum standardized uptake value between the benign or malignant groups(5.7 vs.6.1;p=0.580).Conclusion:In this study,after an incidental finding of an avid intraprostatic lesion on 18F-FDG PEt/Ct,70 of the 231 cases(30.3%;0.8%of the entire cohort)had results c

关键词： Prostatecancer Positionemission tomography Multiparametric magneticresonance imaging Prostatebiopsy

the nonlinear optical properties of a magneto-exciton in a strained Ga_(0.2)In_(0.8)As/GaAs quantum dot

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Chinese Physics B 2013年第10期22卷 479-485页

作者： N.R.Senthil Kumar A.john Peter chang Kyoo Yoo Department of Physics SBM College of Engineering and Technology Department of Physics Govt.Arts CollegeMelur-625 106MaduraiIndia Center for Environmental Studies/Green Energy Center Deptartment of Environmental Science and EngineeringCollege of EngineeringKyung Hee UniversitySeocheon-dong 1Giheung-guYongin-SiGyeonggi-Do446-701South Korea

the magnetic field-dependent heavy hole excitonic states in a strained ***/GaAs quantum dot are investi- gated by taking into account the anisotropy, non-parabolicity of the conduction band, and the geometrical confinement. the strained quantum dot is considered as a parabolic dot of InAs embedded in a GaAs barrier material. the dependence of the effective excitonic g-factor as a function of dot radius and the magnetic field strength is numerically measured. the interband optical transition energy as a function of geometrical confinement is computed in the presence of a mag- netic field. the magnetic field-dependent oscillator strength of interband transition under the geometrical confinement is studied. the exchange enhancements as a function of dot radius are observed for various magnetic field strengths in a strained ***/GaAs quantum dot. Heavy hole excitonic absorption spectra, the changes in refractive index, and the third-order susceptibility of third-order harmonic generation are investigated in the Gao.2Ino.8As/GaAs quantum dot. the result shows that the effect of magnetic field strength is more strongly dependent on the nonlinear optical property in a low-dimensional semiconductor system.

关键词： oscillator strength exciton quantum dot