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营养健康新观察 2012年第1期 40-42页

作者： Olumuyiwa L.Ogegbo Wimal Dissanyake john crowder Olayinka Asekun Oluwole Familoni Christopher J.Branford-White S.W.AnnieBligh 张华琦伦敦都会大学健康研究与政策学院尼日利亚拉各斯大学科学学院化学系

当今,代谢组学研究已广泛应用于解析领域,例如药物的发现和毒理学研究、疾病的诊断以及营养基因组学。由于代谢组学研究自身的优势,它被认为比其他传统的体外研究具备更为广泛的应用前景,目前将代谢组学应用于探索膳食中主要生物活性成... 详细信息

当今,代谢组学研究已广泛应用于解析领域,例如药物的发现和毒理学研究、疾病的诊断以及营养基因组学。由于代谢组学研究自身的优势,它被认为比其他传统的体外研究具备更为广泛的应用前景,目前将代谢组学应用于探索膳食中主要生物活性成分的生化作用已成为研究热点。豆浆是由富含植物雌激素(异黄酮类)的大豆制成。所谓的植物雌激素包括大豆黄酮、三羟异黄酮、大豆黄素、异黄酮苷、染料木苷和黄豆黄苷。与人体中的雌激素相比。

关键词：代谢组学研究 NMR 植物雌激素大豆黄素异黄酮类黄酮苷生化作用染料木苷活性成分毒理学研

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非洲人服用豆浆尿液1H-NMR代谢组学研究

非洲人服用豆浆尿液1H-NMR代谢组学研究

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作者： Olumuyiwa L.Ogegbo Wimal Dissanyake john crowder Olayinka Asekun Oluwole Familoni Christopher J.Branford-White S.W. AnnieBligh 张华琦尼日利亚拉各斯大学科学学院化学系

当今,代谢组学研究已广泛应用于解析领域,例如药物的发现和毒理学研究、疾病的诊断以及营养基因组学。由于代谢组学研究自身的优势,它被认为比其他传统的体外研究具备更为广泛的应用前景,目前将代谢组学应用于探索膳食中主要生物活性成...

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Storylines of family medicine Ⅸ:people and places—diverse populations and locations of care

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Family Medicine and Community Health 2024年第S03期12卷 79-88页

作者： William B Ventres Leslie A Stone Emad R Abou-Arab Julio Meza David S Buck Jerome W crowder Jennifer Y C Edgoose Alexander Brown Ellen J Plumb Amber K Norris Jay J Allen Lauren E Giammar john E Wood Scott M Dickson G Austin Brown Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine University of Michigan Medical SchoolAnn ArborMichiganUSA Family Medicine University of California Los AngelesDavid Geffen School of MedicineLos AngelesCaliforniaUSA Community Medicine University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Social and Behavioral Sciences University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Family Medicine and Community Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA NH Dartmouth Family Medicine Residency ConcordNew HampshireUSA San Francisco VA Medical Center San FranciscoCaliforniaUSA Duluth Family Medicine Residency Program University of Minnesota Medical School Duluth CampusDuluthMinnesotaUSA UAMS Northeast Regional Campus Family Medicine Residency Program JonesboroArkansasUSA Cascades East Family Medicine Residency Program Oregon Health&Science University School of MedicineKlamath FallsOregonUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅸ:people and places—diverse populations and locations of care’,authors address the following themes:‘LGBTQIA+health in family medicine’,‘A family medicine approach to substance use disorders’,‘Shameless medicine for people experiencing homelessness’,“Difficult”encounters—finding the person behind the patient’,‘Attending to patients with medically unexplained symptoms’,‘Making house calls and home visits’,‘Family physicians in the procedure room’,‘Robust rural family medicine’and‘Full-spectrum family medicine’.May readers appreciate the breadth of family medicine in these essays.

关键词： illustration family dimensions

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Principles for managing marine ecosystems prone to tipping points

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Ecosystem Health and Sustainability 2015年第5期1卷 15-32页

作者： Kimberly A.Selkoe Thorsten Blenckner Margaret R.Caldwell Larry B.crowder Ashley L.Erickson Timothy E.Essington James A.Estes Rod M.Fujita Benjamin S.Halpern Mary E.Hunsicker Carrie V.Kappel Ryan P.Kelly john N.Kittinger Phillip S.Levin john M.Lynham Megan E.Mach Rebecca G.Martone Lindley A.Mease Anne KSalomon Jameal F.Samhouri Courtney Scarborough Adrian C.Stier Crow White Joy Zedler National Center for Ecological Analysis and Synthesis 735 State StreetSuite 300Santa BarbaraCalifornia 93101 USA Hawaii Institute of Marine Biology University of HawaiiKaneoheHawaii 96744 USA Stockholm Resilience Centre Stockholm UniversityKra¨ftriket 2B10691 StockholmSweden Center for Ocean Solutions Stanford Woods Institute for the EnvironmentStanford University473 Via Ortega Room 193StanfordCalifornia 94305 USA School of Aquatic and Fishery Sciences University of WashingtonSeattleWashington 98195 USA Department of Ecology and Evolutionary Biology 100 Shaffer RoadUniversity of CaliforniaSanta CruzCalifornia 95060 USA Environmental Defense Fund 123 Mission Street28th FloorSan FranciscoCalifornia 94105 USA Bren School of Environmental Science and Management University of CaliforniaSanta BarbaraCalifornia 93106 USA Imperial College London Silwood Park CampusBuckhurst RoadAscot SL57PY United Kingdom School of Marine and Environmental Affairs University of Washington3707 Brooklyn Avenue NESeattleWashington 98105-6715 USA Conservation International Betty and Gordon Moore Center for Science and Oceans7192 Kalaniana‘ole HighwaySuite G230HonoluluHawaii 96825 USA Conservation Biology Division Northwest Fisheries Science CenterNational Marine Fisheries ServiceNational Oceanic and Atmospheric Administration2725 Montlake Boulevard EastSeattleWashington 98112 USA Department of Economics University of Hawaii at ManoaHonoluluHawaii 96822 USA School of Resource and Environmental Management Simon Fraser UniversityBurnabyBritish Columbia V5A1S6 Canada Department of Biological Sciences California Polytechnic State UniversitySan Luis ObispoCalifornia 93407 USA Botany Department University of WisconsinMadisonWisconsin 53706 USA

As climatic changes and human uses intensify,resource managers and other decision makers are taking actions to either avoid or respond to ecosystem tipping points,or dramatic shifts in structure and function that are often costly and hard to *** indicates that explicitly addressing tipping points leads to improved management *** on theory and examples from marine systems,we distill a set of seven principles to guide effective management in ecosystems with tipping points,derived from the best available *** principles are based on observations that tipping points(1)are possible everywhere,(2)are associated with intense and/or multifaceted human use,(3)may be preceded by changes in earlywarning indicators,(4)may redistribute benefits among stakeholders,(5)affect the relative costs of action and inaction,(6)suggest biologically informed management targets,and(7)often require an adaptive response to *** suggest that early action to preserve system resilience is likely more practical,affordable,and effective than late action to halt or reverse a tipping *** articulate a conceptual approach to management focused on linking management targets to thresholds,tracking early-warning signals of ecosystem instability,and stepping up investment in monitoring and mitigation as the likelihood of dramatic ecosystem change *** approach can simplify and economize management by allowing decision makers to capitalize on the increasing value of precise information about threshold relationships when a system is closer to tipping or by ensuring that restoration effort is sufficient to tip a system into the desired regime.

关键词： critical transition ecosystem-based management marine spatial planning nonlinear relationships restoration ecology stakeholder engagement

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