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透皮东莨菪碱贴剂联合昂丹司琼对比单独应用昂丹司琼用于预防门诊手术后恶心呕吐的一项随机双盲多中心研究

麻醉与镇痛 2010年第5期6卷 34-40页

作者： Tong J. Gan, MD Ashish c. Sinha, MD, PhD Anthony L. Kovac, MD R. Kevin Jones, MD, cPI Stephen A.cohen,MD,MBA Jean P. Battildaa, MS Jonathan S. Deutsch, MD Joseph V. Pergolizzi, Jr., MD] TDS Study Group 王琦(译) 李文志(校) Department of Anesthesiology Duke University Medical Center Durham North Carolina University of Pennsylvania Philadelphia Pennsylvania ＊University of Kansas Medical center Kansas City Kansas Accurate clinical Trials Inc./Saddleback Memorial Medical center Laguna Hills California Beth Israel Deaconess Medical center Boston Massachusetts Baxter Healthcare corporation New Providence New Jersey Departrnent of Medicine Johns Hopkins University School of Medicine Baltimore Maryland The TDS Study Group consists of the following members: Gregory H. Adkisson (St. Agnes Healthcare Inc. Baltimore MD St. Agnes Healthcare Inc. Clinical Research Center Baltimore MD) I(eith Candiotti(University of Miami School of Medidne Jackson Health Systems Miami FL) Stephen & Cohen(Beth Israel Deaconess Medical Center Boston MA) Nell R. Connelly(Baystate Medical Center Springfield MA) Patricia L. Dalby(Magee Women's Hospital of UPMC Pittsburgh PA) Robert D'Angelo(Forsyth Medical Center Winston-Salem NC) Albert R. Davis(Loyola University Medical Center Chicago IL) David 1L Drover (Stanford Hospital and Clinics Stanford CA) Tong J. Gan Fernando Altermatt Dianne Scott(Duke University Medical Center Durham NC Duke Health Raleigh Hospital Raleigh NC and Duke Center for Aesthetic Services Durham NC) Joseph S. Gimbel(AZ Research Center John C. Lincoln Hospital North Mountain and John C. Lincoln Hospital Deer Valley Phoenix AZ)R.Kevin Jones (Saddleback Memorial Medical Center Laguna Hills CA) Anthony L. Kovac(University of Kansas Medical Center Kansas City Kansas KS) John B. Leslie(Mayo Clinic Hospital Phoenix AZ) Roberta McI(inney Jr. (Trinity Clinic North Park Mother Frances Hospital and Tyler Square Tyler TX) Tricia A. Meyer ( Scott and White Hospital Temple TX ) Joseph Pergolizzi (Physicians Day Surgery Center Naples FL) Beverly tC Philip (Brigham and Women's Hospital Boston MA) Martin I. Redmond(State University of New York at Stony Brook Ambulatory Surgica

背景手术后恶心、呕吐（PONV）是门诊手术常见的并发症。本试验目的是观察透皮东莨菪碱贴剂（TDS）联合静脉注射昂丹司琼（OND）对门诊患者PONV的疗效是否优于单独应用昂丹司琼。方法此项随机双盲多中心的临床试验纳入了620例接受门诊... 详细信息

背景手术后恶心、呕吐（PONV）是门诊手术常见的并发症。本试验目的是观察透皮东莨菪碱贴剂（TDS）联合静脉注射昂丹司琼（OND）对门诊患者PONV的疗效是否优于单独应用昂丹司琼。方法此项随机双盲多中心的临床试验纳入了620例接受门诊腹腔镜或隆胸手术的PONV高危女性患者，进入手术室前2小时分别给患者贴上TDS贴剂或外观相同的空白贴剂。在全麻诱导前2—5分钟给所有患者静脉注射OND4mg。手术后24~48小时评估止吐是否完善（彻底止吐标准为无呕吐或干呕，且没有追加止吐药）。同时记录发生呕吐、干呕、恶心以及追加止吐药的患者比例，记录手术后首次发生PONV的时间及离院时间，记录呕吐、干呕、恶心的发作次数与严重程度及患者对于止吐治疗的满意度。结果TDS＋OND组与OND组相比，手术后24小时恶心、呕吐的发生率显著降低，但手术后48小时两者差异无显著性。TDS＋OND组没有呕吐、干呕且未追加过止吐药的患者占48％，而OND组占39％（P〈0．02）。TDS＋OND组的彻底止吐（无恶心、呕吐或干呕，且未追加止吐药）率显著高于OND组（分别为35％和25％，P〈0．01）。TDS＋OND组手术后首次发生恶心、呕吐、干呕及追加止吐药的时间明显晚于OND组（P〈0．05）。前者不良反应的总发生率也低于后者（分别为36．7％和49％，P〈0．01）。结论与单独应用OND相比。TDS＋OND能更大程度地减少PONV，主要是通过减少不良反应而获得。

关键词：手术后恶心呕吐东莨菪碱贴剂多中心研究昂丹司琼门诊手术随机双盲应用单独

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星状玻璃体变性患者眼内3片式硅树脂人工晶体表面钙化:临床病理报道

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世界核心医学期刊文摘（眼科学分册） 2005年第7期1卷 54-54页

作者： Werner L. Kollarits c.R. Mamalis N. Olson R.J. 宋虎平 john A. Moran Eye center University of Utah50 North Medical Drive Salt Lake City UT 84132 United States

Objective: To illustrate the laboratory findings in a patient with bilateral asteroid hyalosiswho presentedwith calcified deposits on a 3- piece silicone intraocular lens (IOL). Design: Observational case report. Methods: A 76- year- old diabetic woman underwent uneventful cataract surgery in 1994 with implantation of a silicone- optic polypropylene- haptic IOL in the left eye. A neodymium:yttrium- aluminum- garnet (Nd:YAG) laser posterior capsulotomy was performed 2 years after cataract surgery, but persistent whitish deposits were observed on the posterior optic surface of the lens. Over the next 3 years, the opacification increased in the region corresponding to the capsulotomy. The IOL was explanted/exchanged. The right eye had cataract surgery in 1995. The acrylic lens implanted in this eye developed no opacities after 6 years. Main Outcome Measures: Gross, microscopic, and surface analyses of the explanted IOL. Results: Gross and light microscopic analyses revealed the presence of confluent crustlike deposits on the central area of the posterior optic surface, as well as Nd:YAG pits. Individual spherules exhibiting a Maltese- cross pattern under polarizing light were also observed. Energy dispersive x- ray spectroscopic analyses demonstrated the composition of the confluent deposits to be similar to hydroxyapatite. conclusions: An association between asteroid hyalosis and dystrophic calcification of IOLs has been reported only with silicone plate haptic designs. The material opacifying the 3- piece silicone lens probably was derived from the asteroid bodies or from the process that results in this vitreous condition. clinical evaluation of other pseudophakic patients with asteroid hyalosis will confirm if this phenomenon is restricted to silicone IOLs.

关键词：玻璃体变性人工晶体硅树脂片式白内障手术玻璃体星状变性白内障摘除光学面晶体植入晶体相

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正常体重、超重及肥胖孕妇伴和不伴先兆子痫时瘦素、脂联素及抑素水平的比较

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世界核心医学期刊文摘（妇产科学分册） 2006年第1期2卷 13-13页

作者： Hendler I. Blackwell S. c. Mehta S. H. 陈霞(译) 高雪莲(校) Dr. I. Hendler Division of Maternal-Fetal-Medicine Department of Obstetrics and Gynecology Hutzel Hospital-Wayne State University 3990 John R Road Detroit MI 48201 United States 不详

The purpose of this study was to compare adipokines’ levels between women with and without preeclampsia based on maternal body mass index (BMI). Study design: This was a cross-sectional study among third-trimester pregnancies with preeclampsia (PIH) compared with normotensive controls. Serum levels of adiponectin, leptin, and resistin were measured before delivery by radioimmunoassay or enzyme-linked immunosorbent assay (ELISA). Results: The study included 22 normotensive and 77 PIH women. Leptin levels increased with maternal BMI. In patients with severe preeclampsia, overweight, and obese women had increased leptin levels (33.4 ± 14.8 vs 23.0 ± 10.8 ng/mL respectively, P = .02), and decreased adiponectin levels (8.4 ± 5.3 vs 12.6 ± 6.0 ng/mL, P = .03) compared with normal weight women. In women with BMI ctin levels increased in patients with preeclampsia compared with controls (11.5 ± 5.6 vs 9.6 ± 4.6 and 7.0 ± 3.2 ng/mL, respectively, P = .005). There was no association between resistin levels and preeclampsia or maternal BMI. conclusion: Women with severe preeclampsia and BMI ≥ 25 kg/m2 have decreased adiponectin and increased leptin levels, while normal weight women with preeclampsia have increased adiponectin levels.

关键词：血清瘦素水平血清脂联素肥胖孕妇先兆于痫正常体重超重抑素 ELISA测定血压正常先兆子痫

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五羟色胺2c受体结构揭示GPcR多重药理学特性的结构基础

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科学新闻 2019年第2期 48-48页

作者：彭瑶 john D.Mccorvy Kasper Harps?e Katherine Lansu Shuguang Yuan Petr Popov Lu Qu Mengchen Pu Tao che Louise F.Nikolajsen Xi-Ping Huang Yiran Wu Ling Shen Walden E.Bj?rn-Yoshimoto Kang Ding Daniel Wacker Gye Won Han Jianjun cheng Vsevolod Katritch Anders A.Jensen Michael A.Hanson Suwen Zhao David E.Gloriam Bryan L.Roth Raymond c.Stevens 刘志杰上海科技大学iHuman研究所中国科学院生物物理研究所上海科技大学

文章简介有些药物往往需要作用于多个靶点,即多重药理学作用发挥其疗效。目前,针对多种血清素受体的药物,包括5-HT2c受体,对治疗肥胖、药物滥用和精神分裂症意义重大。开发具有针对5-HT2c受体选择性的配体或设计具有明确的多重药理学特... 详细信息

文章简介有些药物往往需要作用于多个靶点,即多重药理学作用发挥其疗效。目前,针对多种血清素受体的药物,包括5-HT2c受体,对治疗肥胖、药物滥用和精神分裂症意义重大。开发具有针对5-HT2c受体选择性的配体或设计具有明确的多重药理学特征的药物仍然是极其困

关键词：五羟色胺

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丙型肝炎直接抗病毒药物应用中的药物相互作用管理专家共识

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中华肝脏病杂志 2018年第7期26卷 481-488页

作者：中国肝炎防治基金会中华医学会肝病学分会中华医学会感染病学分会魏来王贵强段钟平不详北京大学人民医院 100044 北京大学第一医院 100034 首都医科大学附属北京佑安医院 100034

总结了中国目前已上市和即将上市的丙型肝炎直接抗病毒药物（DAAs）和治疗方案，分析了DAA的代谢途径，以及慢性丙型肝炎患者常见的合并疾病和常用药物，归纳可能出现的药物相互作用（DDI）相关问题和解决方案，提出DDI的管理意见，包... 详细信息

总结了中国目前已上市和即将上市的丙型肝炎直接抗病毒药物（DAAs）和治疗方案，分析了DAA的代谢途径，以及慢性丙型肝炎患者常见的合并疾病和常用药物，归纳可能出现的药物相互作用（DDI）相关问题和解决方案，提出DDI的管理意见，包括，应用DAAs前管理，DAA应用中的监测以及DAAs治疗完成后的DDI管理。

关键词：肝炎丙型直接抗病毒药管理共识药物相互作用

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卒中一级预防指南美国心脏协会／美国卒中协会对医疗专业人员的声明

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国际脑血管病杂志 2015年第7期23卷 403-439页

作者： James F. Meschia cheryl Bushnell Bernadette Boden-Albala Lynne T. Braun Dawn M. Bravata Seemant chaturvedi Mark A. creager Robert H. Eckel Mitchell S.V. Elkind Myriam Fornage Larry B Goldstein Steven M. Greenberg Susanna E. Horvath costantino Iadecola Edward c. Jauch Wesley S. Moore john A. Wilson 李迪高一鹭陈政弘霍晓川孙海欣孙冬玲茹小娟江滨代表美国心脏协会卒中委员会、心血管和卒中护理委员会、临床心脏病学委员会、功能基因组学和生物转化委员会以及高血压委员会北京市神经外科研究所首都医科大学首都医科大学附属北京天坛医院临床流行病学北京市重点实验室 100050

这份更新版指南旨在为既往无卒中或短暂性脑缺血发作史的人群提供适时的综合性卒中预防循证建议，包括危险因素控制、头颈部动脉粥样硬化性疾病的干预方法以及预防血栓形成和血栓栓塞性卒中的抗栓治疗。此外，本指南还提供了针对遗传和... 详细信息

这份更新版指南旨在为既往无卒中或短暂性脑缺血发作史的人群提供适时的综合性卒中预防循证建议，包括危险因素控制、头颈部动脉粥样硬化性疾病的干预方法以及预防血栓形成和血栓栓塞性卒中的抗栓治疗。此外，本指南还提供了针对遗传和药理学检测以及在其他特殊情况下（包括镰状细胞疾病和卵圆孔未闭）进行卒中预防的建议。

关键词： AHA/ASA科学声明 AF 糖尿病高脂血症高血压颅内动脉瘤缺血预防与控制吸烟卒中

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Accretion in strong field gravity with eXTP

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Science china(Physics,Mechanics & Astronomy) 2019年第2期62卷 45-73页

作者： Alessandra De Rosa Phil Uttley LiJun Gou Yuan Liu cosimo Bambi Didier Barret Tomaso Belloni Emanuele Berti Stefano Bianchi Ilaria caiazzo Piergiorgio casella Marco Feroci Valeria Ferrari Leonardo Gualtieri Jeremy Heyl Adam Ingram Vladimir Karas FangJun Lu Bin Luo Giorgio Matt Sara Motta Joseph Neilsen Paolo Pani Andrea Santangelo XinWen Shu JunFeng Wang Jian-Min Wang YongQuan Xue YuPeng Xu WeiMin Yuan YeFei Yuan Shuang-Nan Zhang Shu Zhang Ivan Agudo Lorenzo Amati Nils Andersson cristina Baglio Pavel Bakala Altan Baykal Sudip Bhattacharyya Ignazio Bombaci NiccolóBucciantini Fiamma capitanio Riccardo ciolfi Wei K.cui Filippo D'Ammando Thomas Dauser Melania Del Santo Barbara De Marco Tiziana Di Salvo chris Done Michal Dovciak Andrew c.Fabian Maurizio Falanga Angelo Francesco Gambino Bruce Gendre Victoria Grinberg Alexander Heger Jeroen Homan Rosario Iaria Jiachen Jiang chichuan Jin Elmar Koerding Manu Linares Zhu Liu Thomas J.Maccarone Julien Malzac Antonios Manousakis Frédéric Marin Andea Marinucci Missagh Mehdipour Mariano Méndez Simone Migliari cole Miller Giovanni Miniutti Emanuele Nardini Paul T.O'Brien Julian P.Osborne Pierre Olivier Petrucci Andrea Possenti Alessandro Riggio Jerome Rodriguez Andrea Sanna LiJing Shao Malgosia Sobolewska Eva Sramkova Abigail L.Stevens Holger Stiele Giulia Stratta Zdenek Stuchlik Jiri Svoboda Fabrizio Tamburini Thomas M.Tauris Francesco Tombesi Gabriel Torok Martin Urbanec Frederic Vincent QingWen Wu Feng Yuan Jean J.M.in't Zand Andrzej A.Zdziarski XinLin Zhou INAF-Istituto di Astrofisica e Planetologie Spaziali Via Fosso del Cavaliere Anton Pannekoek Institute for Astronomy University of Amsterdam National Astronomical Observatories Chinese Academy of Science Institute of High Energy Physics Chinese Academy of Science center for Field Theory and Particle Physics and Department of Physics Fudan University IRAP Universitéde ToulouseCNRSUPSCNES INAF-Osservatorio Astronomico di Brera Department of Physics and Astronomy The University of MississippiUniversity Dipartimento di Matematica e Fisica Universitàdegli studi Roma Tre University of British columbia INAF-Osservatorio Astronomico di Roma INFN-Roma 2 c/o Dipartimento di Fisica II Universit?di Roma"Tor Vergata" Dipartimento di Fisica Universitàdegli Studi di Roma"La Sapienza"&Sezione INFN Roma1 Department of Physics University of OxfordClarendon Laboratory Astronomical Institute Academy of Sciences School of Astronomy and Space Science Nanjing University MIT Kavli Institute for Astrophysics and Space Research Institut für Astronomie und Astrophysik Eberhard Karls Universität Department of Physics Anhui Normal University Department of Astronomy and Institute of Theoretical Physics and Astrophysics Xiamen University cAS Key Laboratory for Research in Galaxies and cosmology Department of AstronomyUniversity of Science and Technology of China Instituto de Astrofísica de Andalucia(cSIc) Glorieta de la Astronomía s/n INAF-Istituto di Astrofisica Spaziale e Fisica cosmica di Bologna Mathematical Sciences and STAG Research centre University of Southampton New York University Abu Dhabi Institute of Physics and Research centre for computational Physics and Data Processing Faculty of Philosophy&ScienceSilesian University in OpavaíBezru?ovo nám. Department of Physics Middle East Technical University Department of Astronomy and Astrophysics Tata Institute of Fundamental Research Dipartimento di Fisica Universit?di Pisa&INFN INAF-Osservatorio Astrofisico di Arcetri INAF-Osservatorio Astronomico di Padova INFN-TIFPA Trento Ins

In this paper we describe the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to accretion flows in the strong field gravity regime around both stellar-mass and supermassive black-holes. eXTP has the unique capability of using advanced "spectral-timing-polarimetry" techniques to analyze the rapid variations with three orthogonal diagnostics of the flow and its geometry, yielding unprecedented insight into the inner accreting regions, the effects of strong field gravity on the material within them and the powerful outflows which are driven by the accretion process.

关键词： X-ray black holes physics accretion

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Emerging contaminants:A One Health perspective

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The Innovation 2024年第4期5卷 140-170,139页

作者： Fang Wang Leilei Xiang Kelvin Sze-Yin Leung Martin Elsner Ying Zhang Yuming Guo Bo Pan Hongwen Sun Taicheng An Guangguo Ying Bryan WBrooks Deyi Hou Damian EHelbling Jianqiang Sun Hao Qiu Timothy MVogel Wei Zhang Yanzheng Gao Myrna JSimpson Yi Luo Scott Xchang Guanyong Su Bryan MWong Tzung-May Fu Dong Zhu Karl JJobst chengjun Ge Frederic coulon Jean Damascene Harindintwali Xiankui Zeng Haijun Wang Yuhao Fu Zhong Wei Rainer Lohmann changer chen Yang Song concepcion Sanchez-cid Yu Wang Ali El-Naggar Yiming Yao Yanran Huang Japhet cheuk-Fung Law chenggang Gu Huizhong Shen Yanpeng Gao chao Qin Hao Li Tong Zhang Natàlia corcoll Min Liu Daniel SAlessi Hui Li Kristian KBrandt Yolanda Pico cheng Gu Jianhua Guo Jianqiang Su Philippe corvini Mao Ye Teresa Rocha-Santos Huan He Yi Yang Meiping Tong Weina Zhang Fidèle Suanon Ferdi Brahushi Zhenyu Wang Syed AHashsham Marko Virta Qingbin Yuan Gaofei Jiang Louis A.Tremblay Qingwei Bu Jichun Wu Willie Peijnenburg Edward Topp Xinde cao Xin Jiang Minghui Zheng Taolin Zhang Yongming Luo Lizhong Zhu Xiangdong Li DamiàBarceló Jianmin chen Baoshan Xing Wulf Amelung Zongwei cai Ravi Naidu Qirong Shen Janusz Pawliszyn Yong-guan Zhu Andreas Schaeffer Matthias c.Rillig Fengchang Wu Gang Yu James M.Tiedje State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China University of chinese Academy of Sciences Beijing 100049China Department of chemistry Hong Kong Baptist UniversityHong KongChina HKBU Institute of Research and continuing Education Shenzhen Virtual University ParkShenzhenChina Technical University of Munich TUM School of Natural SciencesInstitute of Hydrochemistry85748 GarchingGermany School of Resources&Environment Northeast Agricultural UniversityHarbin 150030China climate Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourneVICAustralia Faculty of Environmental Science&Engineering Kunming University of Science&TechnologyKunming 650500China Ministry of Education Key Laboratory of Pollution Processes and Environmental criteria College of Environmental Science and EngineeringNankai UniversityTianjin 300350China Guangdong Key Laboratory of Environmental catalysis and Health Risk control School of Environmental Science and EngineeringInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Ministry of Education Key Laboratory of Environmental Theoretical chemistry South China Normal UniversityGuangzhouGuangdong 510006China Department of Environmental Science Baylor UniversityWacoTXUSA center for Reservoir and Aquatic Systems Research(cRASR) Baylor UniversityWacoTXUSA School of Environment Tsinghua UniversityBeijing 100084China School of civil and Environmental Engineering Cornell UniversityIthacaNY 14853USA Key Laboratory of Microbial Technology for Industrial Pollution control of Zhejiang Province Zhejiang University of TechnologyHangzhou 310014China School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Laboratoire d’Ecologie Microbienne Universite Claude Bernard Lyon 1UMR CNRS 5557UMR INRAE 1418VetAgro Sup69622 VilleurbanneFrance Department of Pla

Environmental pollution is escalating due to rapid global development that often prioritizes human needs over planetary *** global efforts to mitigate legacy pollutants,the continuous introduction of new substances remains a major threat to both people and the *** response,global initiatives are focusing on risk assessment and regulation of emerging contaminants,as demonstrated by the ongoing efforts to establish the UN’s Intergovernmental Science-Policy Panel on chemicals,Waste,and Pollution *** review identifies the sources and impacts of emerging contaminants on planetary health,emphasizing the importance of adopting a One Health *** for monitoring and addressing these pollutants are discussed,underscoring the need for robust and socially equitable environmental policies at both regional and international *** actions are needed to transition toward sustainable pollution management practices to safeguard our planet for future generations.

关键词： pollution planet contaminants

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笔谈:黑暗时期的道德影响力——南京大屠杀期间的拉贝和他的朋友们

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日本侵华南京大屠杀研究 2023年第1期 4-12,139页

作者：柯伟林蓝道夫·特斯塔托尼·孙陈谦平张生姜良芹王卫星杨夏鸣凌曦托马斯·拉贝吕凤悦(整理) 杨倩(整理) 哈佛大学哈佛大学教育研究生院哈佛大学菲利普斯布鲁克公共服务和学术中心南京大学江苏省社会科学院江苏省行政学院《日本侵华南京大屠杀研究》不详

2022年10月18日,由哈佛(上海)中心和南京大学中华民国史研究中心共同主办的学术论坛“道德的力量:南京大屠杀期间的拉贝和他的朋友们”在南京大学召开。来自哈佛大学、南京大学、江苏省社会科学院、江苏省行政学院、侵华日军南京大屠杀... 详细信息

2022年10月18日,由哈佛(上海)中心和南京大学中华民国史研究中心共同主办的学术论坛“道德的力量:南京大屠杀期间的拉贝和他的朋友们”在南京大学召开。来自哈佛大学、南京大学、江苏省社会科学院、江苏省行政学院、侵华日军南京大屠杀遇难同胞纪念馆等单位的专家学者与拉贝后人、大屠杀幸存者一起回顾历史,感怀拉贝事迹,共同探讨道德力量给予人们的历史启示。本组笔谈均选自此次会议。

关键词：南京大学道德影响力拉贝中华民国史学术论坛道德力量黑暗时期南京大屠杀

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Nature:研究利用单细胞分析阐明癌症干细胞在脑癌中的关键角色

引用

现代生物医学进展 2017年第6期17卷 I0003-I0003页

作者： Itay Tirosh, Andrew S. Venteicher, christine Hebert, Leah E. Escalante, Keren Yizhak, Jonathan M. Fisher, christopher Rodman, Mariella G. Filbin, cyril Neftel, Jackson Nyman, Benjamin Izar, Joshua M. Francis, Kenneth J. Livak, Dave Gennert, Rahul Satija, Todd R. Golub, Miguel N. Rivera, Gad Getz, Orit Rozenblatt-Rosen, Bradley E. Bernstein, Aviv Regev Mario L. Suv agrave Andrew S. Venteicher, christine Hebert, Leah E. Escalante, Keren Yizhak, Mariella G. Filbin, cyril Neftel, Niyati Desai, christina c. Luo, Aanand A. Patel, Maristela L. Onozato, Nicolo Riggi, Ravindra Mylvaganam, A. john Iafrate, Matthew P. Frosch, Miguel N. Rivera, Gad Getz, Bradley E. Bernstein, David N. Louis Mario L. Suv agrave Andrew S. Venteicher, Anoop P. Patel, Brian V. Nahed, William T. curry, Robert L. Martuza Daniel P. cahill christopher Mount Michelle Monje Mariella G. Filbin Todd R. Golub Joshua M. Francis Todd R. Golub Aviv Regev Broad Institute of Harvard and MIT Cambridge Massachusetts 02142 USA Department of Pathology and center for cancer Research Massachusetts General Hospital and Harvard Medical School Boston Massachusetts 02114 USA Department of Neurosurgery Massachusetts General Hospital and Harvard Medical School Boston Massachusetts 02114 USA Departments of Neurology Neurosurgery Pediatrics and Pathology Stanford University School of Medicine Stanford California 94305 USA Department of Pediatric Oncology Dana-Farber Cancer Institute and Children’s Hospital Cancer Center Boston Massachusetts 02215 USA Department of Medical Oncology Dana-Farber Cancer Institute Boston Massachusetts 02215 USA Howard Hughes Medical Institute Koch Institute Department of Biology MIT Cambridge Massachusetts 02139 USA

近日。来自麻省总医院、博德研究所及哈佛大学的研究人员通过联合研究，在单细胞水平上对脑瘤基因组进行了分析。他们发现。癌症干细胞或许能够诱发少突神经胶质瘤的发生，少突神经胶质瘤是一种缓慢发展但却非常难以治愈的脑癌，相关研... 详细信息

近日。来自麻省总医院、博德研究所及哈佛大学的研究人员通过联合研究，在单细胞水平上对脑瘤基因组进行了分析。他们发现。癌症干细胞或许能够诱发少突神经胶质瘤的发生，少突神经胶质瘤是一种缓慢发展但却非常难以治愈的脑癌，相关研究刊登于Nature杂志上。同时研究者还首次在人类脑瘤样本中鉴别出了癌症干细胞及其分化的后代细胞。

关键词：干细胞单细胞分析癌症脑瘤神经胶质瘤键角利用研究人员

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