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Innovative seismic retrofitting strategy of added stories isolation system

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Frontiers of Structural and Civil Engineering 2013年第1期7卷 13-23页

作者： Min-Ho CHEY J.Geoffrey CHASE john b.mander Athol J.CARR School of Architecture&Art Yanbian University of Science&TechnologyYanji 133000China Department of Mechanical Engineering University of CanterburyChristchurch 8140New Zealand Zachry Department of Civil Engineering Texas A&M UniversityTexas 77843USA Department of Civil&Natural Resources Engineering University of CanterburyChristchurch 8140New Zealand

The seismic performance of“added stories isolation”(ASI)systems are investigated for 12-story moment resisting *** newly added and isolated upper stories on the top of the existing structure are rolled to act as a large tuned mass damper(TMD)to overcome the limitation of the size of tuned mass,resulting to“12+2”and“12+4”stories building *** isolation layer,as a core design strategy,is optimally designed based on optimal TMD design principle,entailing the insertion of passive flexible laminated rubber bearings to segregate two or four upper stories from a conventionally constructed lower superstructure *** performance metrics are presented for 30 earthquake records from the 3 suites of the SAC *** history analyses are used to compute various response performances and reduction factors across a wide range of seismic hazard *** show that ASI systems can effectively manage seismic response for multi-degree-of freedom(MDOF)systems across a broader range of ground motions without requiring burdensome extra *** results include the identification of differences in the number of added story by which the suggested isolation systems remove energy.

关键词： added stories seismic isolation tuned mass damper parametric optimization statistical method

Targeting Trkb–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang Yu-Wen Alvin Huang john Marshall Department of Molecular biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase b(Trkb)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic Trkb resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with Trkb enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss Trkb-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of Trkb signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with Trkb signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated Trkb.T1 *** Trkb agonists and antibodies that activate Trkb are being intensively investigated,they cannot distinguish the multiple human Trkb splicing isoforms or cell type-specific *** Trkb–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost Trkb signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity Trkb

Aseismic smart building isolation systems under multi-level earthquake excitations： Part II, energy-dissipation and damage reduction

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Frontiers of Structural and Civil Engineering 2015年第3期9卷 297-306页

作者： Min-Ho CHEY J. Geoffrey CHASE john b. mander Athol J. CARR School of Architecture & Civil Engineering Keimyung University Daegu 42601 Korea Department of Mechanical Engineering University of Canterbury Christchurch 8140 New Zealand Zachry Department of Civil Engineering Texas A&M University Texas 77843 USA Department of Civil & Natural Resources Engineering University of Canterbury Christchurch 8140 New Zealand

based on the performance results of the previously suggested smart building isolation systems （lst companion paper）, this following study verifies the control effects of the systems from the view point of energy dissipation and damage level metrics. Several different model cases of the strategically isolated multi-story building structures utilizing passive dampers and semi-active resettable devices are analyzed and the energy-based target indices are compared. Performance comparisons are conducted on statistically calculated story/structural hysteretic energy and story/structural damage demands over realistic suites of earthquake ground motion records, representing seismic excitations of specific return period probability. Again, the semi-active solutions show significant promise for applications ofresettable device, offering advantages over passive systems in the consistent damage reductions. The specific results of this study include the identification of differences in the mechanisms by which smart building isolation systems remove energy, based on the differences in the devices used. Less variability is also seen for the semi-active isolation systems, indicating an increased robustness.

关键词： smart building isolation story and structural energy-dissipation damage assessment

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Attempt to built 13-Hydroxy-9,15-cyclo GA Skeletons

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Chinese Chemical Letters 2002年第12期13卷 1152-1153页

作者： JiangPingLIU LewisN.mander ResearchSchoolofchemistry AustralianNationalUniv.CanberraAustralia0200 TheSchoolofpharmacy yunnanuniversitykunming650091

An easy and mild way to construct 13-hydroxy-9,15-cyclo GA skeletons was reported and it could be used as a general protocol in the synthesis of GAs with this structure.

关键词： Gibberellin(GA) cyclopropyl skeleton cyclo GA structure.

Sifting for small primes from an arithmetic progression

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Science China Mathematics 2023年第12期66卷 2715-2730页

作者： john b.Friedlander Henryk Iwaniec Department of Mathematics University of TorontoTorontoON M5S 2E4Canada Department of Mathematics Rutgers UniversityPiscatawayNJ 08903USA

In this work and its sister paper(Friedlander and Iwaniec(2023)),we give a new proof of the famous Linnik theorem bounding the least prime in an arithmetic *** sieve machinery in both papers,we are able to dispensh with the log-free zero density bounds and the repulsion property of exceptional zeros,two deep innovations begun by Linnik and relied on in earlier proofs.

关键词： sieve small primes Linnik theorem

Highly cross-linked polyethylene is the new‘gold standard’bearing material for total hip arthroplasty

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biosurface and biotribology 2021年第2期7卷 53-59页

作者： john b.Medley Department of Mechanical and Mechatronics Engineering University of WaterlooWaterlooOntarioCanada

Conventional polyethylene is not used much in total hip arthroplasty(THA);it has been supplanted by oxidation-resistant cross-linked polyethylene(≥50 kGy irradiation).However,studies persist that de-emphasize or ignore cross-linked polyethylene.A se-lective literature review is used briefly to present the early use of conventional poly-ethylene and its implication in wear particle-induced osteolysis leading to premature revision *** current situation is established based on Australian registry data and other studies that advocate the use of cross-linked polyethylene in preference to conventional *** some studies suggest caution in using cross-linked polyethylene,overall it is strongly *** the author’s opinion,cross-linked polyethylene is the new reference standard bearing material in THA.

关键词： cross Highly planted

Effect of Reclamation Time and Land Use on Soil Properties in Changjiang River Estuary,China

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Chinese Geographical Science 2011年第4期21卷 403-416页

作者： SUN Yongguang LI Xiuzhen ülo mander HE Yanlong JIA Yue MA Zhigang GUO Wenyong XIN Zaijun State Key Laboratory of Estuarine and Coastal Research East China Normal UniversityShanghai 200062China National Marine Environment Monitor Center Dalian 116023China Department of Geography Institute of Ecology & Earth SciencesUniversity of Tartu46 Vanemuise St.Tartu51014Estonia

The objective of this study is to analyze soil physical and chemical properties,soil comprehensive functions and impact factors after different years of *** on the survey data taken from 216 soil sampling points in the Fengxian Reclamation Area of the Changjiang (Yangtze) River Estuary,China in April 2009 and remotely sensed TM data in 2006,while by virtue of multivariate analysis of variance (MANOVA),geo-statistical analysis (GA),prin-cipal component analysis (PCA) and canonical correspondence analysis (CCA),it was concluded that:1) With the in-crease in reclamation time,soil moisture,soil salinity,soil electric conductivity and soil particle size tended to decline,yet soil organic matter tended to *** available phosphorous tended to increase in the early reclamation period,yet it tended to decline after about 49 years of *** nitrate nitrogen,soil ammonia nitrogen and pH changed slightly in different reclamation *** physical and chemical properties reached a steady state after about 30 years of reclamation.2) According to the results of PCA analysis,the weighted value (0.97 in total) that represents soil nutrient factors (soil nitrate nitrogen,soil organic matter,soil available phosphorous,soil ammonia nitrogen,pH and soil particle size) were higher than the weighted value (0.48 in total) of soil limiting factors (soil salinity,soil elec-tric conductivity and soil moisture).The higher the F value is,the better the soil quality is.3) Different land use types play different roles in the soil function maturity process,with farmlands providing the best contribution.4) Soil physi-cal and chemical properties in the reclamation area were mainly influenced by reclamation time,and then by land use *** correlation (0.1905) of the composite index of soil function (F) with reclamation time was greater than that with land use types (-0.1161).

关键词： soil properties land use types reclamation time soil function Changjiang River Estuary

Study of hybrid nanofluid flow in a stationary cone-disk system with temperature-dependent fluid properties

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 677-694页

作者： A.S.john b.MAHANTHESH G.LORENZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India School of Mathematical and Statistical Sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of Engineering and Architecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such as conical diffusers,medical devices,various rheometric,and viscosimetry *** this study,we investigate the three-dimensional flow of a water-based Ag-Mg O hybrid nanofluid in a static cone-disk system while considering temperature-dependent fluid *** the variable fluid properties affect the dynamics and heat transfer features is studied by Reynolds's linearized model for variable viscosity and Chiam's model for variable thermal *** single-phase nanofluid model is utilized to describe convective heat transfer in hybrid nanofluids,incorporating the experimental *** model is developed as a coupled system of convective-diffusion equations,encompassing the conservation of momentum and the conservation of thermal energy,in conjunction with an incompressibility condition.A self-similar model is developed by the Lie-group scaling transformations,and the subsequent self-similar equations are then solved *** influence of variable fluid parameters on both swirling and non-swirling flow cases is ***,the Nusselt number for the disk surface is *** is found that an increase in the temperature-dependent viscosity parameter enhances heat transfer characteristics in the static cone-disk system,while the thermal conductivity parameter has the opposite effect.

关键词： hybrid nanofluid cone-disk system laminar flow variable fluid property Nusselt number

Nanoparticle meta-grid for enhanced light extraction from light-emitting devices

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Light(Science & Applications) 2020年第1期9卷 842-852页

作者： Debabrata Sikdar john b.Pendry Alexei A.Kornyshev Department of Chemistry Molecular Sciences Research HubImperial College LondonWhite CityLondon W120BZUK Department of Electronics and Electrical Engineering Indian Institute of Technology GuwahatiGuwahati 781039India The blackett Laboratory Department of PhysicsImperial College LondonLondon SW72AZUK Thomas Young Centre for Theory and Simulation of Materials Imperial College LondonLondon SW72AZUK

based on a developed theory,we show that introducing a meta-grid of sub-wavelength-sized plasmonic nanoparticles(NPs)into existing semiconductor light-emitting-devices(LEDs)can lead to enhanced transmission of light across the LED-chip/encapsulant *** results from destructive interference between light reflected from the chip/encapsulant interface and light reflected by the NP meta-grid,which conspicuously increase the efficiency of light extraction from ***“meta-grid”,should be inserted on top of a conventional LED chip within its usual encapsulating *** described by the theory,the nanoparticle composition,size,interparticle spacing,and distance from the LED-chip surface can be tailored to facilitate maximal transmission of light emitted from the chip into its encapsulating layer by reducing the Fresnel *** analysis shows that transmission across a typical LEDchip/encapsulant interface at the peak emission wavelength can be boosted up to ~99%,which is otherwise mere~84% at normal *** scheme could provide improved transmission within the photon escape cone over the entire emission spectrum of an *** would benefit energy saving,in addition to increasing the lifetime of LEDs by reducing ***,the scheme will be easy to implement and adopt into existing semiconductor-device technologies,and it can be used separately or in conjunction with other methods for mitigating the critical angle loss in LEDs.

关键词： light particle reflected