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Clinico-Pa.hologica. Study of Inva.ive Funga. Sinusitis in Iba.a., Nigeria. a.Ca.e Series

Ca.e Reports in Clinica. Medicine 2020年第4期9卷 87-95页

作者： Oluyemi Fa.ina.a.ekunle Da.iel Ga.riel Ola.iyi Ogun john a. babarinde Depa.tment of Ophtha.mology University College Hospital University of Ibadan Ibadan Nigeria Depa.tment of Otorhinola.yngology University College Hospital University of Ibadan Ibadan Nigeria Pa.hology Depa.tment University College Hospital University of Ibadan Ibadan Nigeria

Ba.kground: Inva.ive funga. sinusitis is one of the less common forms of funga. infection more commonly described in North a.rica.a.d a.ia. It a.fects hea.thy a.d immunologica.ly competent individua.s typica.ly complica.ing chronic rhinosinusitis. Surgica. debridement a.d a.juva.t a.tifunga. trea.ment a.e the ma.nsta. of ma.a.ement of this condition. Objective: To describe the clinica. presenta.ion, pa.hologica. fea.ures a.d ma.a.ement of pa.ients with inva.ive funga. sinusitis ma.a.ed a. a.tertia.y hea.th fa.ility, southwestern Nigeria. Method: Medica. records of a.l pa.ients with inva.ive funga. sinusitis ma.a.ed between Ja.ua.y 2009 a.d December 2018 were retrospectively reviewed. Results: Six pa.ients with inva.ive funga. sinusitis were ma.a.ed during the study period. a.l pa.ients were immunocompetent a.d the mea. a.e a. presenta.ion wa. 30.7 yea.s ± 7.2 yea.s. The a.era.e dura.ion of symptoms prior to presenta.ion wa. 18.5 months (Interqua.tile ra.ge, 67.5 months), a.d a.l six pa.ients ha. orbita. involvement a.d intra.ra.ia. extension of the ma.s a. presenta.ion. They a.l ha. surgica. debridement, a.d the specimens were sent for histologica. exa.ina.ion. Mycologica. studies ca.ried out on two specimens isola.ed a.pergillus fumiga.usa. the funga. a.ent a.d a.l pa.ients were sta.ted on post-opera.ive ora. a.tifunga. chemothera.y. Five pa.ients completed their chemothera.y a.d fa.ed well with no recurrence while one pa.ient ha. irregula. a.d incomplete a.tifunga. trea.ment, a.d developed recurrent infection before a.a.doning further trea.ment. Conclusion: Chronic inva.ive funga. sinusitis is a. uncommon infection a.d fa.rly difficult to ma.a.e. However, timely dia.nosis a.d combined surgica. a.d medica. trea.ment ca. give good outcomes in the pa.ients.

关键词： Clinico-Pa.hologica. Fea.ures Iba.a. Immunocompetent Inva.ive Funga. Sinusitis Nigeria

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