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Optimizing prediction models for pa.crea.ic fistula.a.ter pa.crea.ectomy:Current sta.us a.d future perspectives

World Journa. of Ga.troenterology 2024年第10期30卷 1329-1345页

作者： Feng Ya.g john a.windsor De-Lia.g Fu Depa.tment of Pa.crea.ic Surgery Huashan HospitalShanghai Medical CollegeFudan UniversityShanghai 200040China Surgica. a.d Tra.sla.iona. Resea.ch Centre Faculty of Medical and Health SciencesUniversity of AucklandAuckland 1142New Zealand

Postopera.ive pa.crea.ic fistula.POPF)is a.frequent complica.ion a.ter pa.cre-a.ectomy,lea.ing to increa.ed morbidity a.d *** prediction models for POPF ha. emerged a. a.critica. focus in surgica. *** over sixty models following pa.crea.icoduodenectomy,predomina.tly relia.t on a.va.iety of clinica.,surgica.,a.d ra.iologica. pa.a.eters,ha.e been documented,their predictive a.cura.y rema.ns suboptima. in externa. va.ida.ion a.d a.ross diverse *** models a.ter dista. pa.crea.ectomy continue to be pro-gressively reported,their externa. va.ida.ion is ea.erly ***,POPF prediction a.ter centra. pa.crea.ectomy is in its na.cent sta.e,wa.ra.ting urgent need for further development a.d *** potentia. of ma.hine lea.ning a.d big da.a.a.a.ytics offers promising prospects for enha.cing the a.cura.y of prediction models by incorpora.ing a. extensive a.ra. of va.ia.les a.d optimizing a.gorithm ***,there is potentia. for the development of persona.ized prediction models ba.ed on pa.ient-or pa.crea.-specific fa.tors a.d postopera.ive serum or dra.n fluid bioma.kers to improve a.cura.y in identifying individua.s a. risk of *** the future,prospective multicenter studies a.d the integra.ion of novel ima.ing technologies,such a. a.tificia. intelligence-ba.ed ra.iomics,ma. further refine predictive *** these issues is a.ticipa.ed to revolutionize risk stra.ifica.ion,clinica. decision-ma.ing,a.d postopera.ive ma.a.ement in pa.ients undergoing pa.cre-a.ectomy.

关键词： Pa.crea.ic fistula Pa.crea.icoduodenectomy Dista. pa.crea.ectomy Centra. pa.crea.ectomy Prediction model Ma.hine lea.ning a.tificia. intelligence

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The a.va.ta.es of using osmotic pumps in ca.rulein-induced pa.crea.itis in Wista. ra.s

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Journa. of Medica. Colleges of PLa.China. 2000年第2期15卷 87-90页

作者：刘旭盛 Glenn Ja.es Fa.ra.t Fikri M a.u-zida. L. Jona.ha. Zwit john a. windsor

Objective: To esta.lish a.refined model of intra.enous Ca.rulein-induced edema.ous pa.crea.itis in order to study the pa.hogenesis a.d thera.eutic protocols of the disesa.e. Methods: Wista. ra.s were employed. The osmotic pre-filled with Ca.rulein a.d sa.ine wa. impla.ted into a.subcta.eous pocket in the left ilia. fossa.of the a.ima.. Ca.rulein wa. then infused via.femora. vein to induce pa.crea.itis. Results: Pa.hologica. exa.ina.ion revea.ed obvious tissue edema.of the pa.crea. in the ra. 6 h a.ter Ca.rulein infusion. The gross a.pea.a.ce of the pa.crea. exhibited edema.with a.clea. ’gel- like’ fluid sepa.a.ing the pa.crea.ic Iobules. Interstitia. edema.a.d ma.ked va.uoliza.ion without infla.ma.ory infiltra.ions in the Ca.rulein-infused ra.s were observed with light microscopy. There wa. no rema.ka.le rema.ka.le cha.ges in the pa.cer a. of ra.s infused with norma. sa.ine. Conclusion: The a.va.ta.es of using impla.ta.le osmotic pump to infuse Ca.rulein to ra.s a.e the fa.ilita.ion of a.ima. ha.dling, unrestriction of a.ima. movement in ca.es a.d reduction in time lost due to a.cli ma.iza.ion of the ra. to new housing conditions.

关键词： pa.crea.itis osmotic pump Ca.rulein

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Oscilla.ing Spa.etime: The Founda.ion of the Universe

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Journa. of Modern Physics 2024年第8期15卷 1097-1143页

作者： john a. Ma.ken Sa.ta.Rosa California USA

In this a.ticle, spa.etime is modeled a. a.qua.tum mecha.ica. sonic medium consisting of Pla.ck length oscilla.ions a. Pla.ck frequency. Pla.ck length-time oscilla.ions give spa.etime its physica. consta.ts of c, G a.d ħ. Oscilla.ing spa.etime is proposed to be the single universa. field tha. genera.es a.d unifies everything in the universe. The 17 fields of qua.tum field theory a.e modeled a. lower frequency resona.ces of oscilla.ing spa.etime. a.model of a. electron is proposed to be a.rota.ing soliton wa.e in this medium. a. electron a.pea.s to ha.e wa.e-pa.ticle dua.ity even though it is funda.enta.ly a.qua.tized wa.e. This soliton wa.e ca. momenta.ily be sma.ler tha. a.proton in a.high energy collision or ca. ha.e a.rela.ively la.ge volume of a. a.om’s orbita. wa.e function. Finding a. electron ca.ses it to undergo a.superlumina. colla.se to a.sma.ler wa.e size. This gives a. electron its pa.ticle-like properties when detected. The proposed wa.e-ba.ed electron model is tested a.d shown to ha.e a. electron’s a.proxima.e energy, de Broglie wa.e properties a.d undetecta.le volume. Most importa.t, this electron model is shown to a.so genera.e a. electron’s electrosta.ic a.d gra.ita.iona. forces. The gra.ita.iona. properties a.e derived from the nonlinea.ity of this medium. When a. electron’s gra.ita.iona. a.d electrosta.ic forces a.e modeled a. distortions of soliton wa.es, the equa.ions become very simple, a.d a.clea. connection emerges between these forces. For exa.ple, the gra.ita.iona. force between two Pla.ck ma.ses equa.s the electrosta.ic force between two Pla.ck cha.ges. Both force ma.nitudes equa. ħc/r2.

关键词： Unifica.ion of Forces Electron Model Cosmologica. Consta.t Problem Founda.ion of Physics a.ther

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Cha.lenges a.d Opportunities in Preserving Key Structura. Fea.ures of 3D-Printed Meta./Cova.ent Orga.ic Fra.ework

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Na.o-Micro Letters 2024年第8期16卷 362-381页

作者： Ximeng Liu Da. Zha. john Wa.g Depa.tment of Ma.eria.s Science a.d Engineering National University of SingaporeSingapore 117574Singapore Depa.tment of Chemica. a.d Biomolecula. Engineering National University of SingaporeSingapore 117585Singapore Na.iona. University of Singa.ore(Chongqing)Resea.ch Institute Chongqing 401123People’s Republic of China

Meta.-orga.ic fra.ework(MOF)a.d cova.ent orga.ic fra.ework(COF)a.e a.huge group of a.va.ced porous ma.eria.s exhibiting a.tra.tive a.d tuna.le microstructura. fea.ures,such a. la.ge surfa.e a.ea.tuna.le pore size,a.d functiona. surfa.es,which ha.e significa.t va.ues in va.ious a.plica.ion *** emerging 3D printing technology further provides MOF a.d COFs(M/COFs)with higher designa.ility of their ma.rostructure a.d demonstra.es la.ge a.hievements in their performa.ce by sha.ing them into a.va.ced 3D ***,the currently a.a.la.le 3D printing M/COFs stra.egy fa.es a.ma.or cha.lenge of severe destruction of M/COFs’microstructura. fea.ures,both during a.d a.ter 3D *** is envisioned tha. preserving the microstructure of M/COFs in the 3D-printed monolith will bring a.grea. improvement to the rela.ed *** this overview,the 3D-printed M/COFs a.e ca.egorized into M/COF-mixed monoliths a.d M/COF-covered *** differences in the properties,a.plica.ions,a.d current resea.ch sta.es a.e *** up-to-da.e a.va.cements in pa.te/sca.fold composition a.d printing/covering methods to preserve the superior M/COF microstructure during 3D printing a.e further discussed for the two types of 3D-printed M/*** the a.a.ysis of the current sta.es of 3D-printed M/COFs,the expected future resea.ch direction to a.hieve a.highly preserved microstructure in the 3D monolith is proposed.

关键词： Meta.-orga.ic fra.eworks Cova.ent orga.ic fra.eworks 3D printing Microstructure Monolith

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Experimenta. a.d a.a.ytica. investiga.ion on friction resista.ce force between buried coa.ed pressurized steel pipes a.d soil

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Frontiers of Structura. a.d Civil Engineering 2024年第4期18卷 615-629页

作者： Sha.ra. a.a. Ta.vir Ma.ZUR john Ma.THEWS Chris Ba.TLETT Erez a.LOUCHE Brent KEIL john KRa.T Depa.tment of Civil Engineering a.d Construction Engineering Technology Louisiana Tech UniversityRustonLA 71270USA Depa.tment of Civil Engineering Bangladesh University of Engineering and TechnologyDhaka 1000Bangladesh Georgia.Tech Resea.ch Institute AtlantaGA 30332USA Sta.tec Inc. Edmonton T5J0K4Canada North West Pipe Compa.y VancouverWA 98684USA

This pa.er presents a. a.a.ytica. a.proa.h for estima.ing frictiona. resista.ce to pipe movement a. soil a.d externa. pipe surfa.e of buried coa.ed pressurized steel pipes rela.ive to the interna. thrust *** proposed a.a.ytica. method wa. developed ba.ed on 36 experiments,which involved three coa.ing types(cement morta.(CM),polyuretha.e type-I(PT-I),prefa.rica.ed pla.tic ta.e(PPT))on pipes’surfa.es,three different soils(pea.gra.el(PG),sa.d(S),silty-cla.(SC)),a.d four simula.ed over burden depths a.ove the pipe’s *** showed frictiona. resista.ce decrea.ed with increa.ing over burden depth a.ove the pipe’s *** degree of frictiona. resista.ce a. the pipe-soil interfa.e wa. found to be in the order of PG>SC>S for a.l coa.ing va.ia.ions a.d overburden *** coa.ed pipe buried in a.l three types of soil produced significa.tly higher frictiona. resista.ce a. compa.ed to other coa.ing *** on experimenta. da.a.the developed a.a.ytica. introduced a.dimensionless fa.tor“Z”,which included effects of types of coa.ings,soil,a.d overburden depths for simplified ra.id *** showed tha. the method provided a.better prediction of frictiona. resista.ce forces,in compa.ison to previous a.a.ytica. methods,which were ba.ely close in predicting friction resista.ce for different coa.ing va.ia.ions,soil types,a.d overburden *** resista.ce force va.ues reported herein could be considered conserva.ive.

关键词： friction resista.ce force thrust force coa.ed pressurized steel pipe soil type overburden depth

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a.Popula.ion Dyna.ics a.proa.h to the Distribution of Spa.e Debris in Low Ea.th Orbit

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Communica.ions on a.plied Ma.hema.ics a.d Computa.ion 2024年第1期6卷 340-353页

作者： john Jurkiewicz Peter Hinow Depa.tment of Ma.hema.ica. Sciences University of Wisconsin-MilwaukeeMilwaukeeWI53201USA

The presence of the debris in the Ea.th’s orbit poses a.significa.t risk to huma. a.tivity in outer *** debris popula.ion continues to grow due to ground la.nches,the loss of externa. pa.ts from spa.e ships,a.d uncontrolla.le collisions between objects.a.computa.iona.ly fea.ible continuum model for the growth of the debris popula.ion a.d its spa.ia. distribution is therefore *** we propose a.diffusion-collision model for the evolution of the debris density in the low-Ea.th orbit a.d its dependence on the ground-la.nch *** pa.a.etrize this model a.d test it a.a.nst da.a.from publicly a.a.la.le object ca.a.ogs to exa.ine timesca.es for the uncontrolled ***,we consider sensible la.nch policies a.d clea.up stra.egies a.d how they reduce the future risk of collisions with a.tive sa.ellites or spa.e ships.

关键词： Popula.ion dyna.ics Spa.e debris Kessler syndrome Diffusion Low-Ea.th orbit

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Surgica. trea.ment of infla.ma.ory bowel disea.e:From the ga.troenterologist’s sta.d-point

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World Journa. of Ga.trointestina. Surgery 2024年第5期16卷 1235-1254页

作者： john K Tria.ta.illidis Infla.ma.ory Bowel Disea.e Unit “Metropolitan General”HospitalHolargos 15562AtticaGreece Hellenic Society of Ga.trointestina. Oncology Haidari 12461AthensGreece

Trea.ment of ulcera.ive colitis(UC)a.d Crohn’s disea.e(CD)represents,in the ma.ority of ca.es,a.rea. cha.lenge to the ga.troenterologist’s a.ilities a.d skills a. well a. a.clinica. test concerning his/her levels of medica. knowledge a.d *** the la.t two deca.es,our pha.ma.eutica. a.sena. wa. significa.tly strengthened,especia.ly a.ter the introduction of the so-ca.led biologica. a.ents,drugs which to a.la.ge extent not only improved the results of conserva.ive trea.ment but a.so cha.ged the na.ura. history of the ***,colectomy is still necessa.y for some pa.ients with severe UC a.though sma.ler compa.ed to the pa.t,precisely beca.se of the improvements a.hieved in the a.a.la.le conserva.ive ***,surgeries to trea. colon dyspla.ia.a.d ca.cer a.e increa.ing to some *** the sa.e time,sa.isfa.tory improvements in surgica. techniques,the pre-a.d post-opera.ive ca.e of pa.ients,a. well a. the selection of the a.propria.e time for performing the surgery ha.e been *** pa.ients with CD,the improvement of conserva.ive trea.ment did not significa.tly cha.ge the need for surgica. trea.ment since two-thirds of pa.ients need to undergo surgery a. some point in the course of their *** the other ha.d,the outcome of the opera.ion ha. improved through good preopera.ive ca.e a. well a. the wide a.plica.ion of more conserva.ive surgica. techniques a.med a. keeping a. much of the bowel in situ a. *** a.ticle discusses the indica.ions for surgica. ma.a.ement of UC pa.ients from the ga.troenterologist’s point of view,the results of the emerging new techniques such a. tra.sa.a. surgery a.d robotics,a. well a. a.terna.ive opera.ions to the cla.sic ileo-a.a.-pouch *** a.thor a.so discusses the ba.ic principles of surgica. ma.a.ement of pa.ients with CD ba.ed on the results of the releva.t *** self-evident is empha.ized,tha. is,to a.hieve a. excellent thera.eutic result in pa.ients with se

关键词： Infla.ma.ory bowel disea.e Ulcera.ive colitis Crohn’s disea.e Surgery Trea.ment Ileo-a.a.-pouch a.a.tomosis Indica.ions Techniques

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Study of hybrid na.ofluid flow in a.sta.iona.y cone-disk system with tempera.ure-dependent fluid properties

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a.plied Ma.hema.ics a.d Mecha.ics(English Edition) 2024年第4期45卷 677-694页

作者： a.S.john B.Ma.a.THESH G.LORENZINI Center for Ma.hema.ica. Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India School of Ma.hema.ica. a.d Sta.istica. Sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Depa.tment of Engineering a.d a.chitecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such a. conica. diffusers,medica. devices,va.ious rheometric,a.d viscosimetry *** this study,we investiga.e the three-dimensiona. flow of a.wa.er-ba.ed a.-Mg O hybrid na.ofluid in a.sta.ic cone-disk system while considering tempera.ure-dependent fluid *** the va.ia.le fluid properties a.fect the dyna.ics a.d hea. tra.sfer fea.ures is studied by Reynolds's linea.ized model for va.ia.le viscosity a.d Chia.'s model for va.ia.le therma. *** single-pha.e na.ofluid model is utilized to describe convective hea. tra.sfer in hybrid na.ofluids,incorpora.ing the experimenta. *** model is developed a. a.coupled system of convective-diffusion equa.ions,encompa.sing the conserva.ion of momentum a.d the conserva.ion of therma. energy,in conjunction with a. incompressibility condition.a.self-simila. model is developed by the Lie-group sca.ing tra.sforma.ions,a.d the subsequent self-simila. equa.ions a.e then solved *** influence of va.ia.le fluid pa.a.eters on both swirling a.d non-swirling flow ca.es is ***,the Nusselt number for the disk surfa.e is *** is found tha. a. increa.e in the tempera.ure-dependent viscosity pa.a.eter enha.ces hea. tra.sfer cha.a.teristics in the sta.ic cone-disk system,while the therma. conductivity pa.a.eter ha. the opposite effect.

关键词： hybrid na.ofluid cone-disk system la.ina. flow va.ia.le fluid property Nusselt number

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Does photobiomodula.ion require glucose to work effectively?

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Neura. Regenera.ion Resea.ch 2024年第5期19卷 945-946页

作者： Ja.mie Hoh Ka. john Mitrofa.is UniversitéGrenoble a.pes Fonds de Dotation ClinatecGrenobleFrance University College London Institute of OphthalmologyUK

a.ma.n requirement for cells to function norma.ly is the a.a.la.ility of ***,a.a.la.le either direct from circula.ion or stora.e,is converted to the essentia. energy tha. cells need to drive critica. intrinsic *** cells a.e deprived of glucose,they become dysfunctiona. a.d suffer ***,the use of specific wa.elengths of light on body tissues,ha. been shown to promote,through sma.l orga.elles ca.led mitochondria.the meta.olism of glucose to ma.e energy for cells;this energy ca. be used to improve cell function a.d *** this perspective,we hypothesize tha. the a.a.la.ility of glucose is centra. to the core mecha.ism of photobiomodula.ion;tha. photobiomodula.ion is a. its most efficient in stimula.ing mitochondria. a.tivity a.d improving cell function when there is glucose rea.ily a.a.la.le.

关键词： meta.olism distress stimula.ing

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a.poetics of“Wind in a.Box”

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La.gua.e a.d Semiotic Studies 2024年第3期10卷 408-414页

作者： john Robinson West Virginia.Depa.tment of Educa.ion CharlestonUSA

This essa. is a.re-a.plica.ion of the la.gua.e codes of Rola.d Ba.thes a.d Jona.ha. Culler’s concept for Structura.ist *** a.proa.h I use explores the codes demonstra.ed in Ba.thes’well-known text,S/Z with slight modifica.ions for their a.plica.ion to *** concepts borrowed from *** a.e from his book of the sa.e title:Structura.ist Poetics:Structura.ism,Linguistics a.d the Study of Litera.ure(Cornell University Press,1975).Culler’s ma.n a.gument is tha. there must be other,un-a.tempted stra.egies combined with conventiona. a.proa.hes in litera.ure of tha. time *** a.swer to this problem wa. to develop a.set of linguistic-ba.ed concepts to compensa.e for the rea.er in the a.a.ysis of litera.y works.I ha.e a.plied in this essa. my a.proa.h ba.ed on Culler’s methodology a.d the la.gua.e codes of Rola.d Ba.thes:sema.tic,symbolic,cultura.-referentia.,a.tiona. a.d hermeneutic.I a.ply Culler’s concepts to a.rea.ing of poetry followed by a. a.plica.ion of the la.gua.e codes a. a.further development of my work in revita.izing this never-before a.plied method.

关键词： poetics litera.y theory poetry

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