检索结果-南通市图书馆

Polyamines and polyamine-metabolizing enzymes in schizophrenia: Current knowledge and concepts of therapy

World Journal of Psychiatry 2021年第12期11卷 1177-1190页

作者： Hans-Gert Bernstein Gerburg Keilhoff Gregor Laube Henrik Dobrowolny johann steiner Department of Psychiatry University of MagdeburgMagdeburg D-39116Saxony-AnhaltGermany Institute of Biochemistry and Cell Biology University of MagdeburgMagdeburg D-39116Saxony-AnhaltGermany Department of Anatomy ChariteBerlin D-10117Germany

Polyamines play preeminent roles in a variety of cellular functions in the central nervous system and other organs.A large body of evidence suggests that the polyamine pathway is prominently involved in the etiology and pathology of *** in the expression and activity of polyamine metabolizing enzymes,as well as changes in the levels of the individual polyamines,their precursors and derivatives,have been measured in schizophrenia and animal models of the ***,neuroleptic treatment has been shown to influence polyamine concentrations in brain and blood of individuals with ***,the polyamine system may appear to be a promising target for neuropharmacological treatment of ***,for a number of practical reasons there is currently only limited hope for a polyamine-based schizophrenia therapy.

关键词： Polyamines Spermidine Spermine Schizophrenia Animal models Therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between paternal schizophrenia and low birthweight： ADAM12 may matter

引用

Asian Journal of Andrology 2010年第3期12卷 453-454页

作者： Hans-Gert Bernstein Susan MUller johann steiner Nadine Farkas Bernhard Bogerts Uwe Lendeckel Department of Psychiatry University of Magdeburg Magdeburg D-39120 Germany Institute of Medical Biochemistry and Molecular Biology University of Greifswald GreifswaM D-17487 Germany

Dear Editor, I am Dr Hans-Gert Bernstein from the Department of Psychiatry, University of Magdeburg, Germany. Although it is now a well-established fact that mothers with schizophrenia are at higher risk for obstetri... 详细信息

关键词： Association low birthweight ADAM12

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Combining pMINFLUX,graphene energy transfer and DNA-PAINT for nanometer precise 3D super-resolution microscopy

引用

Light(Science & Applications) 2023年第4期12卷 585-592页

作者： Jonas Zähringer Fiona Cole johann Bohlen Florian steiner Izabela Kamińska Philip Tinnefeld Department of Chemistry and Center for NanoScience Ludwig-Maximilians-Universität MünchenButenandtstr.5-13 Haus E81377 MünchenGermany Institute of Physical Chemistry Polish Academy of Sciences Kasprzaka 44/5201-224WarsawPoland Department of Physics Ludwig-Maximilians-Universität MünchenSchellingstra■e 480799 MünchenGermany

3D super-resolution microscopy with nanometric resolution is a key to fully complement ultrastructural techniques with fluorescence ***,we achieve 3D super-resolution by combining the 2D localization of pMINFLUX with the axial information of graphene energy transfer(GET)and the single-molecule switching by *** demonstrate≤2 nm localization precision in all 3 dimension with axial precision reaching below 0.3 *** 3D DNA-PAINT measurements,structural features,i.e.,individual docking strands at distances of 3 nm,are directly resolved on DNA origami *** and GET represent a particular synergetic combination for super-resolution imaging near the surface such as for cell adhesion and membrane complexes as the information of each photon is used for both 2D and axial localization ***,we introduce local PAINT(L-PAINT),in which DNA-PAINT imager strands are equipped with an additional binding sequence for local upconcentration improving signal-to-background ratio and imaging speed of local clusters.L-PAINT is demonstrated by imaging a triangular structure with 6 nm side lengths within seconds.

关键词： resolution transfer precise

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：