检索结果-南通市图书馆

Gastroenterologist perceptions of faecal microbiota transplantation

World Journal of Gastroenterology 2015年第38期21卷 10907-10914页

作者： Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm Gastroenterology and Hepatology Department St Vincent’s Hospital Centre for Digestive Diseases Gastroenterology and Hepatology Department Bankstown-Lidcombe Hospital Gastroenterology and Hepatology Department Nambour General Hospital Gastroenterology and Hepatology Department Liverpool Hospital University of New South Wales School of Biotechnology and Biomolecular Sciences Departments of Gastroenterology and Medicine St Vincent's Hospital and University of Melbourne

AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required.

关键词： Perceptions Gastroenterologist Clostridium diffici

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Droplet microreactor for high-throughput fluorescence-based measurements of single catalyst particle acidity

引用

Microsystems & Nanoengineering 2023年第2期9卷 101-111页

作者： Jeroen C.Vollenbroek Anne-Eva Nieuwelink johan G.Bomer Roald M.Tiggelar Albert van den Berg Bert M.Weckhuysen Mathieu Odijko BIOS Lab on a Chip Group MESA+InstituteUniversity of TwenteHallenweg 157522 NH EnschedeThe Netherlands inorganic Chemistry and Catalysis Debye Institute for Nanomaterials ScienceUtrecht UniversityUniversiteitsweg 993584 CG UtrechtThe Netherlands NanoLab Cleanroom MESA+InstituteUniversity of TwenteHallenweg 157522 NH EnschedeThe Netherlands

The particles of heterogeneous catalysts differ greatly in size,morphology,and most importantly,in activity.Studying these catalyst particles in batch typically results in ensemble averages,without any information at the level of individual catalyst particles.To date,the study of individual catalyst particles has been rewarding but is stll rather slow and often cumbersomel.Furthermore,these valuable in-depth studies at the single particle level lack statistical relevance.Here,we report the development of a droplet microreactor for high-throughput fluorescence-based measurements of the acidities of individual particles in fluid catalytic cracking(FCC)equilibrium catalysts(ECAT).This method combines systematic screening of single catalyst particles with statistical relevance.An oligomerization reaction of 4-methoxystyrene,catalyzed by the Bronsted acid sites inside the zeolite domains of the ECAT particles,Was performed on-chip at 95 ℃.The fluorescence signal generated by the reaction products inside the ECAT particles was detected near the outlet of the microreactor.The high-throughput acidity screening platform was capable of detecting~1000 catalyst particles at a rate of 1 catalyst particle every 2.4 s.The number of detected catalyst particles was representative of the overall catalyst particle population with a confidence level of 95%.The measured fluorescence intensities showed a clear acidity distribution among the catalyst particles,with the majority(96.1%)showing acidity levels belonging to old,deactivated catalyst particles and a minority(3.9%)exhibiting high acidity levels.The latter are potentially of high interest,as they reveal interesting new physicochemical properties indicating why the particles were still highly acidic and reactive.

关键词： catalyst acidity particle

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform

引用

Microsystems & Nanoengineering 2017年第1期3卷 294-301页

作者： Burcu Gumuscu johan G.Bomer Hans L.de Boer Albert van den Berg Jan C.T.Eijkel BIOS Lab-on-a-Chip Group MESA+Institute for NanotechnologyMIRA Institute for Biomedical Technology and Technical MedicineUniversity of Twente7500 AE EnschedeThe Netherlands

A new approach is presented for preparative,continuous flow fractionation of sub-10-kbp DNA fragments,which exploits the variation in the field-dependent mobility of the DNA molecules based on their length.Orthogonally pulsed electric fields of significantly different magnitudes are applied to a microchip filled with a sieving matrix of 1.2% agarose gel.Using this method,we demonstrate a high-resolution separation of 0.5,1,2,5,and 10 kbp DNA fragments within 2 min.During the separation,DNA fragments are also purified from other ionic species.Preparative fractionation of sub-10-kbp DNA molecules plays an important role in second-generation sequencing.The presented device performs rapid high-resolution fractionation and it can be reliably manufactured with simple microfabrication procedures.

关键词： agarose gel biased reptation continuous flow DNA separation DNA purification preparative fractionation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Multiscale friction model for hot sheet metal forming

引用

Friction 2022年第2期10卷 316-334页

作者： Jenny VENEMA Javad HAZRATI Eisso ATZEMA David MATTHEWS Ton van den BOOGAARD Tata Steel Research&DevelopmentCA Ijmuiden 1970the Netherlands Nonlinear Solid Mechanics Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 NBthe Netherlands Laboratory for Surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 NBthe Netherlands

The accurate description of friction is critical in the finite element(FE)simulation of the sheet metal forming process.Usually,friction is oversimplified through the use of a constant Coulomb friction coefficient.In this study,the application of an existing multiscale friction model is extended to the hot stamping process.The model accounts for the effects of tool and sheet metal surface topography as well as the evolution of contact pressure,temperature,and bulk strain during hot stamping.Normal load flattening and strip drawing experiments are performed to calibrate the model.The results show that the model can relatively well predict friction in strip draw experiments when the tool surface evolution due to wear is incorporated.Finally,the application of the formulated multiscale friction model was demonstrated in the FE simulation of a hot-stamped part.

关键词： tribology wear friction hot stamping friction model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

全球牛奶和奶制品供需趋势

引用

四川奶业 2008年第3期 25-25页

作者： johan van den Berg 蕴之（译）荷兰Veepro Hollad杂志社社长不详

全世界对鲜牛奶和奶制品的需求在不断地增长。人们越来越多地具有购买牛奶的可能性。这些发展的明确结果是：奶农销售牛奶的价格也随之而增长（在荷兰已上扬至0．40欧元）。其实涨价的原因很简单。总的牛奶供应量远不能满足需求量的增... 详细信息

全世界对鲜牛奶和奶制品的需求在不断地增长。人们越来越多地具有购买牛奶的可能性。这些发展的明确结果是：奶农销售牛奶的价格也随之而增长（在荷兰已上扬至0．40欧元）。其实涨价的原因很简单。总的牛奶供应量远不能满足需求量的增加。因为全球市场牛奶供应紧缺，于是就出现了欧盟将及时提高产奶配额的预测。这就导致奶农们需求增加更多的奶牛，以及他们将更少合格的青年母牛出售。

关键词：鲜牛奶奶制品供需趋势全球市场青年母牛供应量需求量奶农

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

用硬开关VIENNA Boost转换器描述AlGaN/GaN/AlGaN功率双异质结场效应晶体管

引用

电力电子 2011年第1期9卷 35-39页

作者： Jordi Everts Pieter Jacqmaer Ratmir Gelagaev johan Driesen Jeroen van den Keybus Jo Das Marianne Germain 田琦袁立强 KULeuven Belgium Triphase Belgium Imec Belgium Imec BelgiumKULeuvenBelgium 清华大学电机系

一种高频、硬开关boost转换器(VIENNA拓扑)被用来描述新型AlGaN/GaN/A1GaN功率双异质结场效应晶体管(DHEFTs)在运行状态下的特性。这种变换器可以让我们精确地测量出功率电路设计中最重要的器件参数(动态开通电阻R_(dyn),门极漏极电荷Q_... 详细信息

一种高频、硬开关boost转换器(VIENNA拓扑)被用来描述新型AlGaN/GaN/A1GaN功率双异质结场效应晶体管(DHEFTs)在运行状态下的特性。这种变换器可以让我们精确地测量出功率电路设计中最重要的器件参数(动态开通电阻R_(dyn),门极漏极电荷Q_(gd),密勒电荷Q_(gd),开通电压V_(th),开关时间t_(on)和t_(off),质品因数FOM……)。通过采用正确的测量手段和自行开发的精确度/分辨率改进电路可以实现高度准确性。在A1GaN/GaN/AIGaN DHEFTs样品上进行的动态开通电阻和门极电荷的测量得到了很好的结果。

关键词：硬开关转换器场效应晶体管

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The effect of particle size and amount of inoculum on fungal treatment of wheat straw and wood chips

引用

Journal of Animal Science and Biotechnology 2017年第1期8卷 217-225页

作者： Sandra J. A. van Kuijk Anton S. M. Sonnenberg johan J. P. Baars Wouter H. Hendriks John W. Cone Animal Nutrition Group Wageningen University De Elst 1 6708WD Wageningen The Netherlands Plant Breeding Wageningen University Droevendaalsesteeg 1 6708PB Wageningen The Netherlands

Background： The aim of this study was to optimize the fungal treatment of lignocellulosic biomass by stimulating the colonization. Wheat straw and wood chips were treated with Ceriporiopsis subvermispora and Lentinula edodes with various amounts of colonized millet grains（0.5, 1.5 or 3.0 % per g of wet weight of substrate） added to the substrates. Also, wheat straw and wood chips were chopped to either 0.5 or 2 cm.Effectiveness of the fungal treatment after 0, 2, 4, 6, or 8 wk of incubation was determined by changes in chemical composition, in vitro gas production（IVGP） as a measure for rumen degradability, and ergosterol content as a measure of fungal biomass.Results： Incomplete colonization was observed for C. subvermispora treated wheat straw and L. edodes treated wood chips. The different particle sizes and amounts of inoculum tested, had no significant effects on the chemical composition and the IVGP of C. subvermispora treated wood chips. Particle size did influence L.edodes treatment of wheat straw. The L. edodes treatment of 2 cm wheat straw resulted in a more selective delignification and a higher IVGP than the smaller particles. Addition of 1.5 % or 3 % L. edodes inoculum to wheat straw resulted in more selective delignification and a higher IVGP than addition of 0.5 % inoculum.Conclusion： Particle size and amount of inoculum did not have an effect on C. subvermispora treatment of wood chips. At least 1.5 % L. edodes colonized millet grains should be added to 2 cm wheat straw to result in an increased IVGP and acid detergent lignin（ADL） degradation.

关键词： Amount of inoculum Fungal treatment In vitro rumen degradability Lignin degradation Lignocellulosic biomass Particle size

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of substrates and underlayer on CNT synthesis by plasma enhanced CVD

引用

Advances in Manufacturing 2013年第3期1卷 236-240页

作者： Liang Xu Di Jiang Yi-Feng Fu Stephane Xavier Shailendra Bansropun Afshin Ziaei Shan-Tung Tu johan Liu Division of Process Equipment Science and Engineering School of Mechanical and Power EnigneeringEast China University of Science and Technology BioNano Systems Laboratory Department of Microtechnology and Nanoscience(MC2)Chalmers University of Technology SHT Smart High Tech AB Thales Research and Technology Key Laboratory of New Displays and System Integration SMIT Centerand School of Mechatronics and Mechanical EngineeringShanghai University

Due to their unique thermal, electronic and mechanical properties, carbon nanotubes （CNTs） have aroused various attentions of many researchers. Among all the techniques to fabricate CNTs, plasma enhanced chemical vapor deposition （PECVD） has been extensively developed as one growth technique to produce verticallyaligned car bon nanotubes （VACNTs）. Though CNTs show a trend to be integrated into nanoelectromechanical system （NEMS）, CNT growth still remains a mysterious technology. This paper attempts to reveal the effects of substrates and un derlayers to CNT synthesis. We tried five different substrates by substituting intrinsic Si with high resistivity ones and byincreasing the thickness of SiO2 insulativity layer. And also, we demonstrated an innovative way of adjusting CNT den sity by changing the thickness of Cu underlayer.

关键词： Carbon nanotube （CNT） - Substrate Underlayer Effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：