检索结果-南通市图书馆

Gastroenterostoma after Billroth antrectomy as a premalignant condition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第25期18卷 3201-3206页

作者： Robert Sitarz Ryszard Maciejewski Wojciech P Polkowski G johan A Offerhaus Department of Pathology University Medical CentreUtrecht3584 CX UtrechtThe Netherlands Department of human Anatomy Medical University of Lublin20-950 LublinPoland Department of Surgical Oncology Medical University of Lublin20-081 LublinPoland Department of Pathology Academic Medical Centre 1105 AZ Amsterdam The Netherlands

Gastric stump carcinoma （GSC） following remote gastric surgery is widely recognized as a separate entity within the group of various types of gastric cancer. Gastrecto- my is a well established risk factor for the development of GSC at a long time after the initial surgery. Both exo- as well as endogenous factors appear to be involved in the etiopathogenesis of GSC, such as achlorhydria, hypergastrinemia and biliary reflux, Epstein-Barr virus and helicobacter pylori infection, atrophic gastritis, and also some polymorphisms in interleukin-l~ and maybe cyclo-oxygenase-2. This review summarizes the litera- ture of GSC, with special reference to reliable early di- agnostics. In particular, dysplasia can be considered as a dependable morphological marker. Therefore, close endoscopic surveillance with multiple biopsies of the gastroenterostomy is recommended. Screening start- ing at 15 years after the initial ulcer surgery can detect tumors at a curable stage. This approach can be ofspecial interest in Eastern European countries, where surgery for benign gastroduodenal ulcers has remained a practice for a much longer time than in Western Eu- rope, and therefore GSC is found with higher frequency.

关键词： Gastric stump cancer Gastrectomy Riskfactors Endoscopic surveillance

Study of industrially applied methods for verification, validation and uncertainty quantification of simulator models

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Modeling, Simulation, and Scientific Computing 2015年第2期6卷 56-84页

作者： Magnus Eek Sogol Kharrazi hampus Gavel johan Olvander Saab Aeronautics Linkoping SE-58188Sweden Swedish National Road and Transport Research Institute(VTI)Linkoping SE-58195Sweden Linkoping University Linkoping SE-58183Sweden

To better utilize the potential of system simulation models and simulators,industrially applicable methods for Verification,Validation and Uncertainty Quantification(VV&UQ)are *** paper presents an exploratory case study of VV&UQ techniques applied on models integrated in aircraft system simulators at Saab Aeronautics and in driving simulators at the Swedish National Road and Transport Research Institute(VTI).Results show that a large number of Verification and Validation(V&V)techniques are applied,some of which are promising for further development and use in simulator credibility *** the application of UQ,a large gap between academia and this part of industry has been identified,and simplified methods are *** applicability of the NASA Credibility Assessment Scale(CAS)at the studied organizations is also evaluated and it can be concluded that the CAS is considered to be a usable tool for achieving a uniform level of V&V for all models included in a simulator,although its implementation at the studied organizations requires tailoring and coordination.

关键词： Simulator credibility simulation model verification validation uncertainty quantification V&V VV&UQ NASA Credibility Assessment Scale

Subregion graph: A path planning acceleration structure for characters with various motion types in very large environments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computational Visual Media 2015年第2期1卷 105-118页

作者： Nicholas Mario Wardhana henry johan hock Soon Seah Multi-plAtform Game Innovation Centre(MAGIC) Nanyang Technological University School of Computer Engineering Nanyang Technological University Fraunhofer IDM NTU Nanyang Technological University

Modern computer graphics applications commonly feature very large virtual environments and diverse characters which perform different kinds of motions. To accelerate path planning in such a scenario, we propose the subregion graph data structure. It consists of subregions, which are clusters of locally connected waypoints inside a region, as well as subregion connectivities. We also present a fast algorithm to automatically generate a subregion graph from an enhanced waypoint graph map representation,which also supports various motion types and can be created from large virtual environments. Nevertheless,a subregion graph can be generated from any graphbased map representation. Our experiments show that a subregion graph is very compact relative to the input waypoint graph. By firstly planning a subregion path, and then limiting waypoint-level planning to this subregion path, over 8 times average speedup can be achieved, while average length ratios remain as low as102.5%.

关键词： path planning acceleration very large environments motion types abstraction

Diagnosis and management of microscopic colitis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第48期14卷 7280-7288页

作者： Curt Tysk johan Bohr Nils Nyhlin Anna Wickbom Sune Eriksson Department of Medicine Division of Gastroenterology rebro University Hospital and School of Health and Medical Sciences rebro University Department of Pathology rebro University Hospital

Microscopic colitis, comprising collagenous and lymphocytic colitis, is characterized clinically by chronic watery diarrhea, and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscoplc incidence of each disorder examination. The annual is 4-6/100000 inhabitants, with a peak incidence in 60-70-year-old individuals and a noticeable female predominance for collagenous colitis. The etiology is unknown. Chronic diarrhea, abdominal pain, weight loss, fatigue and fecal incontinence are common symptoms, which impair the health-related quality of life of the patient. There is an association with other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented shortterm treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.

关键词： Microscopic colitis Collagenous colitis Lymphocytic colitis Chronic diarrhea Budesonide

Gastric accommodation assessed by ultrasonography

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第18期12卷 2825-2829页

作者： Odd helge Gilja johan Lunding Trygve hausken hans Gregersen National Centre for Ultrasound in Gastroenterology Haukeland University HospitalInstitute of MedicineUniversity of BergenBergenNorway Center for Visceral Biomechanics and Pain Aalborg Hospitaland Center for Sensory-motor InteractionAalborg UniversityDenmark

Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three different meanings： The accommodation process, the accommodation reflex, and the accommodation response. The gastric accommodation process is a complex phenomenon that describes how the size of the gastric compartment changes in response to a meal. The electronic barostat is considered the gold standard in assessing gastric accommodation. Imaging methods, including MRI, SPECT, and ultrasonography may also be used, particularly in patients who are stress-responsive, e.g. functional dyspepsia patients, as a non-invasive and less stress-inducing method is favourable. Ultrasonography satisfies these criteria as it does not by itself distort the physiological response in stress-responsive individuals.

关键词： Ultrasonography Gastric accommodation Stomach Barostat Gastric relaxation 3D ultrasound

A New Enantiornithes(Aves) from the Early Cretaceous of China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2014年第4期88卷 1034-1040页

作者： johan DALSTT Per G.P.ERICSON Zhonge ZhOU Department of Vertebrate Zoology Swedish Museum of Natural History Department of Geological Sciences Stockholm University Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences

A new bird from the early Cretaceous Yixian Formation of Liaoning, China is described. This new species, Grabauornis lingyuanensis, shares several synapomorphies with the Enantiornithes. The specimen is relatively well preserved. The skeletal morphology of Grabauornis bears close resemblance to that of other Chinese members of this clade. The brachial index （the ratio between the lengths of humerus and ulna） is 0.95, which is close to the average for enantiornithine birds. It indicates that Grabauornis was a rather good flyer, and the presence of an alula in the wing further testifies to this.

关键词： Enantiornithes Aves Early Cretaceous Yixian Formation Liaoning China

Reduced-particle size wheat bran and endoxylanase supplementation in broiler feed affect arabinoxylan hydrolysis and fermentation with broiler age differently

在线全文

学校读者我要写书评

暂无评论

Animal Nutrition 2023年第1期12卷 308-320页

作者： An Bautil Michael R.Bedford johan Buyse Christophe M.Courtin Laboratory of Food Chemistry and Biochemistry Department of Microbial and Molecular Systems(M2S)KU LeuvenLeuven3001Belgium AB Vista MarlboroughWiltshire SN84ANUnited Kingdom Laboratory of Livestock Physiology Department of BiosystemsKU LeuvenLeuven3001Belgium

Since the caecal microbiota of young broilers are not yet able to ferment the dietary fibre(DF)fraction of the feed to a large extent,increasing the accessibility of DF substrates along the gastrointestinal tract is crucial to benefit from the health stimulating metabolic end-products(*** acid)generated upon microbial DF ***,the present study aimed to evaluate the potential of reduced-particle size wheat bran(RPS-WB)and endoxylanases as feed additives to stimulate arabinoxylan(AX)hydrolysis and fermentation along the hindgut of young *** this end,RPS-WB and endoxylanase supplementation were evaluated in a 2×2 factorial design using a total of 256 male 1-d-old chicks(Ross 308).Broilers were assigned to 4 dietary treatments:a basal wheat-based diet with(1)no feed additives(control,CTRL),(2)an endoxylanase(XYL;Econase XT 25 at 0.10 g/kg diet),(3)1%wheat bran with an average reduced particle size of 297μm(RPS-WB)and(4)an endoxylanase and 1%RPS-WB(RPS-WB+XYL).Each dietary treatment was replicated 8 times and on d 10 and 28,respectively,24 and 16 broilers per treatment group were euthanised to analyse AX degradation,short-chain fatty acid production and digesta viscosity in the ileum and *** receiving XYL in their diet showed increased AX solubilisation and fermentation at both d 10 and 28 compared to the CTRL group(Phe diet stimulated wheat AX utilisation by the primary AX degraders in the caecum at 10 d of age compared to the CTRL group,as observed by the high AX digestibility coefficient for the RPS-WB supplemented group at this young age(Pht gains but increased butyric acid concentrations compared to the XYL and CTRL group(Phough no synergistic effect for RPS-WB+XYL broilers was observed for AX hydrolysis and fermentation,these findings suggest that both additives can raise a dual benefit to the broiler as a butyrogenic effect and im

关键词： Broiler chicken Wheat bran Particle size reduction Xylanase Arabinoxylan fermentation

Risk factors and outcomes for patients with pancreatic cancer undergoing surgical exploration without resection due to metastatic disease:A national cohort study

在线全文

学校读者我要写书评

暂无评论

hepatobiliary & Pancreatic Diseases International 2022年第3期21卷 279-284页

作者： Emil Sahlstrom Paulina Bereza-Carlson johan Nilsson Bobby Tingstedt Bodil Andersson Department of Clinical Sciences Lund SurgeryLund UniversitySweden Department of Surgery Central Hospital KristianstadSweden Department of Translational Medicine Cardiothoracic surgery and bioinformaticsLund UniversitySweden Department of Thoracic and vascular surgery Skane University hospitalLundSweden Department of Surgery Skane University HospitalLundSweden

Background:Unresectable disease is sometimes diagnosed during surgery in patients with pancreatic ductal adenocarcinoma(PDAC).This study aimed to identify preoperative risk factors for metastatic disease diagnosed at surgical exploration and to investigate and compare survival in resected and nonresected ***:Patients were identified from the Swedish National Pancreatic and Periampullary Cancer Registry *** of metastatic disease were evaluated with a multivariable logistic regression model,and survival was evaluated with Kaplan-Meier estimates and log-rank ***:In total,1938 patients with PDAC were scheduled for *** unresectable situation was diagnosed intraoperatively in 399 patients(20.6%),including 234(12.1%)with metastasized *** risk factors for metastasis were involuntary weight loss(OR=1.72;95%CI:1.27-2.33)and elevated carbohydrate antigen 19-9(CA19-9)(35-599 U/m L,OR=1.79,95%CI:1.11-2.89;≥600 U/m L,OR=3.24,95%CI:2.04-5.17).Overall survival was lower among patients with metastasized disease than that among patients with a resectable tumor(Pht loss and an elevation of CA19-9 are preoperative risk factors for diagnosing metastasized disease during surgical exploration.

关键词： Pancreatic cancer Surgery Metastasized Exploration

Evolution of gastroenterology training

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第15期15卷 1793-1798页

作者： hanna Telleman Trevlyn Felicity Burger Chris Jacob johan Mulder Department of Gastroenterology and hepatology VU Medical Center Department of Gastroenterology Witwatersrand University

There have been rapid developments in gastroenterology(GE)over the last *** until the late 1980s,GE-training was incorporated in Internal Medicine *** introduction of endoscopy has necessitated the need for additional *** the world different national boards have developed their own curricula which will be discussed in this paper. Emphasis will be placed on the curriculum recently introduced in The *** internal medicine component has become a two-year requirement (Common Trunk)and the duration of training in GE has been extended to four *** of the growing complexity of GE,there are now four subspecialties:Interventional Endoscopy,Neuromotility, Oncology and hepatology that trainees can choose *** subspecialties each have predefined specific *** World Gastroenterology Organization has drawn up a standard curriculum which can be of help to the boards in different countries. The curriculum emphasizes the knowledge and skill *** curriculum also defines the training recommendations,the requirements of training facilities and competence evaluation of fellows and facilities,while less is said about research,finance and the number of gastroenterologists *** the coming decades the curriculum will need to be revised *** of the curriculum will be the next challenge for the years to come.

关键词： Career Common Trunk Curriculum Endoscopy Fellow Fellowship Gastroenterology hepatology Program Training