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A primer on the use of probability generating functions in infectious disease modeling

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Infectious Disease Modelling 2018年第1期3卷 192-248页

作者： joel c.Miller Institute for Disease Modeling BellevueWAUSA

We explore the application of probability generating functions(PGFs)to invasive processes,focusing on infectious disease introduced into large *** goal is to acquaint the reader with applications of PGFs,moreso than to derive new *** help predict a number of properties about early outbreak behavior while the population is still effectively infinite,including the probability of an epidemic,the size distribution after some number of generations,and the cumulative size distribution of non-epidemic *** show how PGFs can be used in both discrete-time and continuous-time settings,and discuss how to use these results to infer disease parameters from observed *** the large population limit for susceptible-infected-recovered(SIR)epidemics PGFs lead to survival-function based models that are equivalent to the usual mass-action SIR models but with fewer *** use these to explore properties such as the final size of epidemics or even the dynamics once stochastic effects are *** target this primer at biologists and public health researchers with mathematical modeling experience who want to learn how to apply PGFs to invasive diseases,but it could also be used in an applications-based mathematics course on *** include many exercises to help demonstrate concepts and to give practice applying the *** summarize our main results in a few *** we provide a small python package which performs many of the relevant calculations.

关键词： generating functions negligible

Mathematical models of SIR disease spread with combined non-sexual and sexual transmission routes

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Infectious Disease Modelling 2017年第1期2卷 35-55页

作者： joel c.Miller Monash University School of Mathematical SciencesMelbourne 3800Australia Institute for Disease Modeling BellevueWAUSA

The emergence of Zika and Ebola demonstrates the importance of understanding the role of sexual transmission in the spread of diseases with a primarily non-sexual transmission *** this paper,we develop low-dimensional models for how an SIR disease will spread if it transmits through a sexual contact network and some other transmission mechanism,such as direct contact or *** show that the models derived accurately predict the dynamics of simulations in the large population limit,and investigateℛ0 and final size relations.

关键词： network Mathematical spread

Optimizing care for ST-elevation myocardial infarction patients： application of systems engineering

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Journal of Geriatric cardiology 2016年第11期13卷 883-887页

作者： joel A. Strom charles Sand Lyndon c. Box Florida Polytechnic University IST Building 4700 Research Way Lakeland FL USA Department of Emergency Medicine St. Joseph's Hospital 3001 W. Dr. Martin Luther King Jr. Blvd. Tampa FL USA Air Methods Bayflite 701 6th St S St. Petersburg FL USA West Valley Medical Group 1906 Fairview Ave #230 Caldwell ID USA

Timely reperfusion for patients with an ST-elevation myocardial infarction （STEMI） reduces myocardial cell loss resulting in preserved LV performance, a reduced incidence of congestive heart failure, and significantly lower early and late mortality, while conversely, any delay in reperfusion has a deleterious effect on morbidity and mortality.

关键词： Primary percutaneous angioplasty ST-elevation myocardial infarction care systems

Guest editorial: Network architectures and communication protocols for smart industrial IoT applications

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Digital communications and Networks 2023年第2期9卷 293-295页

作者： Fazlullah Khan joel J.P.c.Rodrigues Mian Ahmad Jan Department of computer Science Abdul Wali Khan University Mardan23200Khyber PakhtunkhwaPakistan Federal University of Piauí(UFPI) Brazil Instituto de TelecomunicaçoesPortugal

The rapid growth in hardware technologies and the fourth industrial revolution-Industry 4.0 have enabled the Internet of Things(IoT)to be *** of the main drivers in Industry 4.0 is smart and secured Industrial IoT(IIoT)[1].The IIoT results from the widespread use of computers and the interconnectedness of *** has made software a crucial tool for almost every industry,from bakeries and arts to manufacturing facilities and healthcare systems[2].The IIoT devices can be mobile and geographically distributed over a long distance,which exposes them to network disturbances,Quality of Service(QoS)degradation,and security *** addition,the IIoT is a complex network at a large scale,and there is a dire need for network architecture and protocol design to accommodate these diverse domains and competencies and handle the increasing levels of ***,in this special issue,we aim to focus on the challenges of network architectures and communication protocol design in the context of the smart *** special issue has attracted numerous high-quality research articles and has accepted fourteen research papers[3–16].

关键词： IoT network communication

Aggregator Based RPL for an IoT-Fog Based Power Distribution System with 6LoWPAN

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china communications 2020年第1期17卷 104-117页

作者： Rijo Jackson Tom Suresh Sankaranarayanan Victor Hugo c.de Albuquerque joel J.P.c.Rodrigues cMR Institute of Technology Bengaluru 560037India SRM Institute of Science and Technology Chennai 603203India University of Fortaleza(Unifor) FortalezaCE 60811-905Brazil Federal University of Piaui Teresina-PI64049-550Brazil Instituto de Telecomunicacoes 1049-001 LisboaPortugal

Advanced Metering Infrastructure(AMI)forms an important part in Smart *** the data effectively from smart meters to the Edge/Fog node requires an efficient routing *** Protocol for Low Power Lossy Area Network(RPL)is a standard routing protocol for IPv6 over Low Power Personal Area Network(6LoWPAN).In a Power Distribution system all the smart meters together form 6LoWPAN *** communicate with the fog router,which acts as the 6LoWPAN *** was evaluated using cooja Network simulator for a power distribution network *** nodes which were far away from the fog node gave low Packet Delivery Ratio(PDR)and large End to End *** paper proposes an aggregation RPL scheme by modifying the existing contiki *** smart meter nodes communicate to the aggregator,which communicates to the fog *** results show that the aggregation scheme has 35.6%increase in PDR,lesser hop count and 13.24%decrease in End to End delay on an average compared to existing RPL.

关键词： IoT 6LoWPAN RPL routing distribution automation smart grid fog computing

Reduced Annealing Time and Enhanced Magnetocaloric Effect of La(Fe,Al)13 Alloy by La-nonstoichiometry and Si-doping

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Acta Metallurgica Sinica(English Letters) 2020年第11期33卷 1535-1542页

作者： Liang Yang Jun Li Defang Tu joel c.J.Strickland Qiaodan Hu Hongbiao Dong Jianguo Li School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Engineering University of LeicesterLeicester LE17RHUK collaborative Innovation center for Advanced Ship and Deep-Sea Exploration Shanghai Jiao Tong UniversityShanghai 200240China

LaFe13-x Mx(M=Si,Al)alloys are promising for use in magnetic ***,they require long annealing time(30 days)in order to optimize the magnetocaloric *** has shown that the addition of extra La in off-stoichiometric alloys can greatly shorten the annealing ***,the purpose of this study is to investigate the influence of the extra addition of La on the annealing properties of a new off-stoichiometric La1.7Fe11.6Al1.4-xSix(x=0,0.1,0.4)*** was demonstrated that after a 36 h annealing time,a large volume fraction of 1:13 magnetocaloric phase was obtained for all *** microstructural analysis of the off-stoichiometric La1.7Fe11.6Al1.4-xSix alloys revealed a facet-like grain *** La1.7Fe11.6Al1.4 and La1.7Fe11.6Al1Si0.4 alloys were shown to contain large 1:13 phase precipitates separated in a La-rich matrix,while the La1.7Fe11.6Al1.3Si0.1 alloy had a continuous 1:13 phase matrix with a fine dispersion of La-rich precipitates *** the magnetic field varied between 0 and 2 T,the corresponding magnetic entropy change and relative cooling capacity for the La1.7Fe11.6Al1.3Si0.1 specimen were determined as 4.58 J/kg K and 173.6 J/kg,*** importantly,the La1.7Fe11.6Al1.3Si0.1 alloy displayed only a slight volume change when the meta-magnetic phase transition occurred,which is promising for cyclic use.

关键词： Solidifi cation Magnetic properties Heat treatment Microstructure Functional alloys

Achieving timely percutaneous reperfusion for rural ST-elevation myocardial infarction patients by direct transport to an urban PcI-hospital

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Journal of Geriatric cardiology 2016年第10期13卷 840-845页

作者： charles-Lwanga K Bennin Saif Ibrahim Farah Al-Saffar Lyndon c Box joel A Strom Valley cardiology Fayetteville North Carolina USA Division of cardiology Department of Medicine University of Florida College of Medieine Jacksonville Jaeksonville Florida USA Division of cardiovascular Diseases Mayo Clinic Seottsdale Arizona USA West Valley Medical Group Caldwell Idaho USA Florida Polytechnic University Lakeland Florida USA

Backgrounds ST-elevation myocardial infarction （STEMI） guidelines recommend reperfusion by primary percutaneous coronary in- tervention （PcI） ≤ 90 min from time of first medical contact （FMc）. This strategy is challenging in rural areas lacking a nearby PcI-capable hospital. Recommended reperfusion times can be achieved for STEMI patients presenting in rural areas without a nearby PcI-capable hospital by ground transportation to a central PcI-capable hospital by use of protocol-driven emergency medical service （EMS） STEMI field triage protocol. Methods Sixty STEMI patients directly transported by EMS from three rural counties （Nassau, camden and charlton counties） within a 50-mile radius of University of Florida Health-Jacksonville （UFHJ） from 01/01/2009 to 12/31/2013 were identified from its PcI registry. The STEMI field triage protocol incorporated three elements：（1） a cooperative agreement between each of the rural emergency medical service （EMS） agency and UFHJ; （2） performance of a pre-hospital EcG to facilitate STEMI identification and laboratory activation; and （3） direct transfer by ground transportation to the UFHJ cardiac catheterization laboratory. FMc-to-device （FMc2D）, door-to-device （D2D）, and transit times, the day of week, time of day, and EMS shift times were recorded, and odds ratio （OR） of achieving FMc2D times was calculated. Results FMc2D times were shorter for in-state STEMIs （81 ± 17 vs. 87± 19 min）, but D2D times were similar （37 ± 18 vs. 39 ± 21 min）. FMc2D 〈 90 min were achieved in 82.7% in-state STEMIs compared to 52.2% for out-of-state STEMIs （OR = 4.4, 95% cI： 1.24-15.57; P = 0.018）. FMc2D times were homogenous after adjusting for weekday vs. weekend, EMS shift times. Nine patients did not meet FMc2D ≤ 90 min. Six were within 10 min of target; all patient achieved FMc2D 〈 120 min. conclusions Guideline-compliant FMc2D ≤90 min is achievable for rural STEMI patients within a 50 mile radius of a PcI-capable hospital by use of protocol-driv

关键词： Myocardial infarction Percutaneous coronary intervention Systems of care

Fuzzy Aggregator Based Energy Aware RPL Routing for IoT Enabled Forest Environment

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computers, Materials & continua 2022年第8期72卷 4039-4055页

作者： S.Srividhya Suresh Sankaranarayanan Sergei A.Kozlov joel J.P.c.Rodrigues Department of Data Science and Business Systems School of ComputingSRM Institute of Science and TechnologyChennai603203TamilnaduIndia Department of Networking and communications School of ComputingSRM Institute of Science and TechnologyChennai603203TamilnaduIndia ITMO University St.PetersburgRussia Senac Faculty of ceará FortalezaCEBrazil Instituto de Telecomunicações Covilhã6201-001Portugal

Forested areas are extremely vulnerable to disasters leading to environmental *** Fire is one among them which requires immediate *** are lot of works done by authors where Wireless Sensors and IoT have been used for forest fire ***,towards monitoring the forest fire and managing the energy efficiently in IoT,Energy Efficient Routing Protocol for Low power lossy networks(E-RPL)was *** were challenges about the scalability of the network resulting in a large end-to-end delay and less packet delivery which led to the development of Aggregator-based Energy Efficient RPL with Data compression(cAAERPL).Though cAA-ERPL proved effective in terms of reduced packet delivery,less energy consumption,and increased packet delivery ratio for varying number of nodes,there is still challenge in the selection of aggregator which is based purely on probability percentage of *** has been research work where fuzzy logic been employed for Mobile Ad-hoc Routing,RPL routing and cluster head selection in Wireless *** has been no work where fuzzy logic is employed for aggregator selection in Energy Efficient *** accordingly,we here have proposed Fuzzy Based Aggregator selection in Energy-efficient RPL for region thereby forming DODAG for communicating to Fog/*** here have developed fuzzy inference rules for selecting the aggregator based on strength which takes residual power,Node degree,and Expected Transmission count(ETX)as input *** Fuzzy Aggregator Energy Efficient RPL(FA-ERPL)based on fuzzy inference rules were analysed against E-RPL in terms of scalability(First and Half Node die),Energy consumption,and aggregator node energy *** the analysis,it was found that FA-ERPL performed better than *** were simulated using MATLAB and results.

关键词： Fuzzy logic aggregator IoT RPL routing wireless sensor network

Review of operative considerations in spinal cord stem cell therapy

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World Journal of Stem cells 2021年第2期13卷 168-176页

作者： Pavan S Upadhyayula joel R Martin Robert c Rennert Joseph D ciacci Department of Neurological Surgery University of CaliforniaSan DiegoLa JollaCA 92037United States

Spinal cord injury(ScI)can permanently impair motor and sensory function and has a devastating cost to patients and the United States healthcare *** cell transplantation for treatment of ScI is a new technique aimed at creating biological functional *** techniques in stem cell transplantation for ScI are *** review various clinical treatment paradigms,surgical techniques and technical considerations important in ScI *** NcBI PubMed database was queried for“ScI”and“stem cell”with a filter placed for“clinical trials”.Thirty-nine articles resulted from the search and 29 were included and evaluated by study authors.A total of 10 articles were excluded(9 not ScI focused or transplantation focused,1 canine model).Key considerations for stem cell transplantation include method of delivery(intravenous,intrathecal,intramedullary,or excision and engraftment),time course of treatment,number of treatments and time from injury until *** are no phase III clinical trials yet,but decreased time from injury to treatment and a greater number of stem cell injections both seem to increase the chance of functional recovery.

关键词： Stem cell Spinal cord injury Operative techniques Stem cell transplantation Intramedullary