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Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural regeneration research 2025年第3期20卷 813-814页

作者： joel Gruchot Laura reiche Andrew Chan robert Hoepner Patrick Küry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HErV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

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Epididymis cholesterol homeostasis and sperm fertilizing ability

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Asian Journal of Andrology 2011年第1期13卷 11-17页

作者： Fabrice Saez Ouvrier and joel r Drevet UMr GreD CNrS 6247 INSERM U931 Clermont Universite Equipe ＇Epididyme et maturation des gametes＇ Aubiere cedex 63171 France

Cholesterol, being the starting point of steroid hormone synthesis, is a long known modulator of both female and male reproductive physiology especially at the level of the gonads and the impact cholesterol has on gametogenesis. Less is known about the effects cholesterol homeostasis may have on postgonadic reproductive functions. Lately, several data have been reported showing how imbalanced cholesterol levels may particularly affect the post-testicular events of sperm maturation that lead to fully fertile male gametes. This review will focus on that aspect and essentially centers on how cholesterol is important for the physiology of the mammalian epididymis and spermatozoa.

关键词： cholesterol homeostasis epididymosomes fertility post-testicular maturation spermatozoa

The epididymal immune balance:a key to preserving male fertility

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Asian Journal of Andrology 2019年第6期21卷 531-539页

作者： Allison Voisin Fabrice Saez joel r Drevet rachel Guiton Team Mechanisms of Posttesticular Infertility GReD LaboratoryCNRS UMR 6293-INSERM U1103 University of Clermont Auvergne Clermont-Ferrand 63001France

Up to 15%of male in fertility has an immuno logical origi n,either due to repetitive infections or to autoimmune resp on ses mainly affecting the epididymis,prostate,and *** observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital *** a consequenee,the epididymis,in which posttesticular spermatozoa mature and are stored,has raised some in terest in recent years when it comes to its immune mecha *** deed,sperm cells are produced at puberty,long after the establishment of self-toleranee,and they possess unique surface proteins that cannot be recognized as *** are potential targets of the immune system,with the risk of inducing autoantibodies and consequently male *** immunity is based on a finely tuned equilibrium between efficient immune responses to pathogens and strong tolerance to sperm *** processes rely on incompletely described molecules and cell *** review compiles recent studies focusing on the immune cell types populating the epididymis,and proposes hypothetical models of the organization of epididymal immunity with a special emphasis on the immune response,while also discussing important aspects of the epididymal immune regulation such as tolerance and tumour control.

关键词： epididymis immune response lymphocytes mononuclear phagocytes toleranee

Optical properties of Weyl semimetals

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National Science review 2019年第2期6卷 206-208页

作者： joel E.Moore Department of Physics University of California Materials Science Division Lawrence Berkeley National Laboratory

The behavior of electrons in ordinary metals is dominated by physics near the Fermi surface. Indeed, many of the first successes of the quantum theory of solids, such as understanding the large specific heat of metals, followed from applications of the Fermi surface concept. Great effort has been devoted in recent years to semimetals in which the Fermi surface shrinks to a set of Dirac or Weyl points, where four

关键词： As Ta Optical properties of Weyl semimetals

Effect of Cambering on the Aerodynamic Performance of Heaving Airfoils

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Journal of Bionic Engineering 2009年第4期6卷 398-404,406-407页

作者： joel E.Guerrero Postdoctoral research Fellow Department of CivilEnvironmental and Architectural EngineeringUniversity of GenoaVia Montallegro 1Genoa16145Italy

In the present work,a parametric numerical study is conducted in order to assess the effect of airfoil cambering on the aerodynamic performance of rigid heaving *** incompressible Navier-Stokes equations are solved in their velocity-pressure formulation using a second-order accurate in space and time finite-difference *** tackle the problem of moving boundaries,the governing equations are solved on overlapping structured *** numerical simulations are performed at a reynolds number of re=1100 and at different values of Strouhal number and reduced *** results obtained show that the airfoil cambering geometric parameter has a strong influence on the average lift coefficient,while it has a smaller impact on the average thrust coefficient and propulsive efficiency of heaving airfoils.

关键词： heaving airfoils structured overlapping grids incompressible Navier-Stokes equations airfoil cambering

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Science： a world without borders

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Protein & Cell 2015年第8期6卷 551-552页

作者： joel Haywood CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China

In 2010 the effects of the global financial crisis were still being felt in the UK. Stock market confidence levels were low, unemployment levels were high and job opportunities were few and far between especially for new graduates with little work experience. Unfortunately for my partner, her recent graduation and search for job opportunities within the finance and law sector could not have come at a more unsuitable time. China however had better weathered the storm of the financial crisis and presented itself as a more familiar and fruitful climate for my partner to further develop her career. Furthermore.

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The evolution and refinements of varicocele surgery

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Asian Journal of Andrology 2016年第2期18卷 171-178,J0002页

作者： joel L Marmar Director of Men's Health Services Planned Parenthood of Southern New Jersey 317 S. Broadway Camden NJ 08103 USA.

Varicoceles had been recognized in clinical practice for over a century. Originally, these procedures were utilized for the management of pain but, since 1952, the repairs had been mostly for the treatment of male infertility. However, the diagnosis and treatment of varicoceles were controversial, because the pathophysiology was not clear, the entry criteria of the studies varied among centers, and there were few randomized clinical trials. Nevertheless, clinicians continued developing techniques for the correction of varicoceles, basic scientists continued investigations on the pathophysiology of varicoceles, and new outcome data from prospective randomized trials have appeared in the world＇s literature. Therefore, this special edition of the Asian Journal of Andrology was proposed to report much of the new information related to varicoceles and, as a specific part of this project, the present article was developed as a comprehensive review of the evolution and refinements of the corrective procedures.

关键词： antegrade sclerosis laparoscopic varicocelectomy microsurgical varicocelectomy percutaneous embolization varicocelectorny

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高分子科学与工程

ON THE ALGOrITHMIC COMPLEXITY OF STATIC STrUCTUrES

作者： joel r.·Fried

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Journal of Systems Science & Complexity 2010年第6期23卷 1037-1053页

作者： joel rATSABY J. CHASKALOVIC joel rATSABY Dept. of Electrical and Electronics Engineering Ariel University Center of Samaria Ariel Israel Department of Mathematics Ariel University Center of Samaria Ariel Israel and IJLRDA University Pierre and Marie Curie-Paris VI France.

This paper provides a first indication that this is true for a system comprised of a static structure described by hyperbolic partial differential equations and is subjected to an external random input force. The system deforms the randomness of an input force sequence in proportion to its algorithmic complexity. The authors demonstrate this by numerical analysis of a one-dimensional vibrating elastic solid （the system） on which we apply a maximally-random force sequence （input）. The level of complexity of the system is controlled via external parameters. The output response is the field of displacements observed at several positions on the body. The algorithmic complexity and stochasticity of the resulting output displacement sequence is measured and compared against the complexity of the system. The results show that the higher the system complexity, the more random-deficient the output sequence.

关键词： Data compression descriptional complexity randomness static structure.