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Family Medicine and Community Health 2018年第3期6卷 142-153页

作者： Michael D.Fetters joanna Rew joel j.heidelbaugh Department of Family Medicine 1018 Fuller StreetAnn ArborMI 48104-1213USA Department of Family Medicine University of Michigan24 Frank Lloyd Wright DriveSuite 2300Ann ArborMI 48105USA Department of Family Medicine 200 Arnet StreetSuite 200YpsilantiMI 48198USA

This article describes and reflects on the role of teaching practices in undergraduate medical education on the basis of teaching experience in the United States of *** in particular,but also other family medicine-emerging countries,continues to embark on a path of creating and embracing a family medicine-centric *** purpose of this article is to provide a US perspective on teaching priorities and strategies for medical students,and how these fit into a larger structure of the family medicine clinical *** emphasize knowledge,clinical skills,clinical behaviors,and strategies for succeeding as a *** introduce key aspects of the University of Michigan family medicine clerkship and the highly effective structure provided by the leadership of the course *** organizational structure provides a framework for implementing the family medicine clerkship for teaching medical *** China and other family medicine-emerging countries increasingly embrace the discipline,we hope these ideas will provide a meaningful reference.

关键词： Primary care general practice medical education clinical clerkship family medicine practice teaching consulting skills

Storylines of family medicine Ⅶ: family medicine across the lifespan

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Family Medicine and Community Health 2024年第S3期12卷 61-69页

作者： William B Ventres Leslie A Stone Katharine C Barnard Sara G Shields Mark j Nelson Maria Verónica Svetaz Clara M Keegan joel j heidelbaugh Paige B Beck Lucille Marchand Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine and Community Health UMass Chan Medical SchoolWorcesterMassachusettsUSA john Peter Smith Hospital Family Medicine Residency Fort WorthTexasUSA Family and Community Medicine Hennepin HealthcareMinneapolisMinnesotaUSA Family Medicine University of Vermont Larner College of MedicineBurlingtonVermontUSA Family Medicine University of Michigan Medical SchoolAnn ArborMichiganUSA Family Medicine and Community Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅶ:family medicine across the lifespan’,authors address the following themes:‘Family medicine maternity care’,‘Seeing children as patients brings joy to work’,‘Family medicine and the care of adolescents’,‘Reproductive healthcare across the lifespan’,‘Men’s health’,‘Care of older adults’,and‘Being with dying’.May readers appreciate the range of family medicine in these essays.

关键词： life illustration family

ON THE ALGORITHMIC COMPLEXITY OF STATIC STRUCTURES

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journal of Systems Science & Complexity 2010年第6期23卷 1037-1053页

作者： joel RATSABY j. CHASKALOVIC joel RATSABY Dept. of Electrical and Electronics Engineering Ariel University Center of Samaria Ariel Israel Department of Mathematics Ariel University Center of Samaria Ariel Israel and IJLRDA University Pierre and Marie Curie-Paris VI France.

This paper provides a first indication that this is true for a system comprised of a static structure described by hyperbolic partial differential equations and is subjected to an external random input force. The system deforms the randomness of an input force sequence in proportion to its algorithmic complexity. The authors demonstrate this by numerical analysis of a one-dimensional vibrating elastic solid （the system） on which we apply a maximally-random force sequence （input）. The level of complexity of the system is controlled via external parameters. The output response is the field of displacements observed at several positions on the body. The algorithmic complexity and stochasticity of the resulting output displacement sequence is measured and compared against the complexity of the system. The results show that the higher the system complexity, the more random-deficient the output sequence.

关键词： Data compression descriptional complexity randomness static structure.

Eggshell and environmental bacteria contribute to the intestinal microbiota of growing chickens

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journal of Animal Science and Biotechnology 2020年第4期11卷 1245-1260页

作者： joel j.Maki Elizabeth A.Bobeck Matthew j.Sylte Torey Looft Food Safety and Enteric Pathogens Research Unit National Animal Disease CenterAgricultural Research ServiceUS Department of Agriculture1920 Dayton AveAmesIA 50010USA Interdepartmental Microbiology Graduate Program Iowa State University|AmesIA 50011USA Oak Ridge Institute for Science and Education ARS Research Participation ProgramOak RidgeTN 37830USA Department of Animal Science Iowa State UniversityAmesIA 50011USA.

Background: The initial intestinal microbiota acquired from different sources has profound impacts on animal health and productivity. In modern poultry production practices, the source(s) of the establishing microbes and their overall contribution during development of gastrointestinal tract communities are still unclear. Using fertilized eggs from two independent sources, we assessed the impact of eggshell-and environmental-associated microbial communities on the successional processes and bacterial community structure throughout the intestinal tract of chickens for up to 6 weeks ***: Culturing and sequencing techniques identified a viable, highly diverse population of anaerobic bacteria on the eggshell. The jejunal, ileal, and cecal microbial communities for the egg-only, environment-only, and conventionally raised birds generally displayed similar successional patterns characterized by increasing community richness and evenness over time, with strains of Enterococcus, Romboutsia, and unclassified Lachnospiraceae abundant for all three input groups in both trials. Bacterial community structures differed significantly based on trial and microbiota input with the exception of the egg-exposed and conventional birds in the jejunum at week 1 and the ileum at week 6. Cecal community structures were different based on trial and microbiota input source, and cecal short-chain fatty acid profiles at week 6 highlighted functional differences as ***: We identified distinct intestinal microbial communities and differing cecal short-chain fatty acid profiles between birds exposed to the microbiota associated with either the eggshell or environment, and those of conventionally hatched birds. Our data suggest the eggshell plays an appreciable role in the development of the chicken intestinal microbiota, especially in the jejunum and ileum where the community structure of the eggshellonly birds was similar to the structure of conventionally hatched birds

关键词： 16S rRNA gene Eggshell microbiota Environmental microbiota Hatching Intestinal colonization SCFA Succession

Exercise intolerance in heart failure with preserved ejection fraction： more than a heart problem

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journal of Geriatric Cardiology 2015年第3期12卷 294-304页

作者： Bharathi Upadhya Mark j Haykowsky joel Eggebeen Dalane W Kitzman Cardiology and Geriatrics Wake Forest School of Medicine Medical Center Blvd Winston Salem NC USA Faculty of Rehabilitation Medicine University of Alberta Edmonton AB Canada

Heart failure （HF） with preserved ejection fraction （HFpEF） is the most common form of HF in older adults, and is increasing in preva- lence as the population ages. Furthermore, HFpEF is increasing out of proportion to HF with reduced EF （HFrEF）, and its prognosis is worsening while that of HFrEF is improving. Despite the importance of HFpEF, our understanding of its pathophysiology is incomplete, and optimal treatment remains largely undefined. A cardinal feature of HFpEF is reduced exercise tolerance, which correlates with symptoms as well as reduced quality of life. The traditional concepts of exercise limitations have focused on central dysfimction related to poor cardiac pump function. However, the mechanisms are not exclusive to the heart and lungs, and the understanding of the pathophysiology of this dis- ease has evolved. Substantial attention has focused on defining the central versus peripheral mechanisms underlying the reduced functional capacity and exercise tolerance among patients with HF. In fact, physical training can improve exercise tolerance via peripheral adaptive mechanisms even in the absence of favorable central hemodynamic function. In addition, the drug trials performed to date in HFpEF that have focused on influencing cardiovascular function have not improved exercise capacity. This suggests that peripheral limitations may play a significant role in HF limiting exercise tolerance, a hallmark feature of HFpEF.

关键词： Exercise intolerance Heart failure Perioheral limitations Skeletal muscle

Guest editorial: Network architectures and communication protocols for smart industrial IoT applications

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Digital Communications and Networks 2023年第2期9卷 293-295页

作者： Fazlullah Khan joel j.P.C.Rodrigues Mian Ahmad jan Department of Computer Science Abdul Wali Khan University Mardan23200Khyber PakhtunkhwaPakistan Federal University of Piauí(UFPI) Brazil Instituto de TelecomunicaçoesPortugal

The rapid growth in hardware technologies and the fourth industrial revolution-Industry 4.0 have enabled the Internet of Things(IoT)to be *** of the main drivers in Industry 4.0 is smart and secured Industrial IoT(IIoT)[1].The IIoT results from the widespread use of computers and the interconnectedness of *** has made software a crucial tool for almost every industry,from bakeries and arts to manufacturing facilities and healthcare systems[2].The IIoT devices can be mobile and geographically distributed over a long distance,which exposes them to network disturbances,Quality of Service(QoS)degradation,and security *** addition,the IIoT is a complex network at a large scale,and there is a dire need for network architecture and protocol design to accommodate these diverse domains and competencies and handle the increasing levels of ***,in this special issue,we aim to focus on the challenges of network architectures and communication protocol design in the context of the smart *** special issue has attracted numerous high-quality research articles and has accepted fourteen research papers[3–16].

关键词： IoT network communication

Adult celiac disease with acetylcholine receptor antibody positive myasthenia gravis

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World journal of Gastroenterology 2009年第38期15卷 4741-4744页

作者： Hugh j Freeman Helen R Gillett Peter M Gillett joel Oger Department of Medicine (Gastroenterology and Neurology) University of British Columbia

Celiac disease has been associated with some autoimmune disorders. A 40-year-old competitive strongman with celiac disease responded to a gluten-free diet, but developed profound and generalized motor weakness with acetylcholine receptor antibody positive myasthenia gravis, a disorder reported to occur in about 1 in 5000. This possible relationship between myasthenia gravis and celiac disease was further explored in serological studies. Frozen stored serum samples from 23 acetylcholine receptor antibody positive myasthenia gravis patients with no intestinal symptoms were used to screen for celiac disease. Both endomysial and tissue transglutaminase antibodies were examined. One of 23 (or, about 4.3%) was positive for both IgA-endomysial and IgA tissue transglutaminase antibodies. Endoscopic studies subsequently showed duodenal mucosal scalloping and biopsies confirmed the histopathological changes of celiac disease. Celiac disease and myasthenia gravis may occur together more often than is currently appreciated. The presence of motor weakness in celiac disease may be a clue to occult myasthenia gravis, even in the absence of intestinal symptoms.

关键词： Acetylcholine receptor antibodies Celiacdisease Myasthenia gravis Transglutaminase antibodies

Modified activated carbon with interconnected fibrils of iron-oxyhydroxides using Mn^(2+) as morphology regulator, for a superior arsenic removal from water

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journal of Environmental Sciences 2019年第2期31卷 403-414页

作者： Cesar Nieto-Delgado joel Gutiérrez-Martínez j.Rene Rangel-Méndez Environmental Sciences Division Potosino Institute of Scientific and Technological ResearchIPICyT

The arsenic removal efficiency of iron-modified activated carbons depends greatly on the number of available iron oxide surface sites, which are given by the surface area of the anchored particles. In this sense, aiming the generation of an adsorbent with superior arsenic adsorption capacity, we developed a protocol to anchor interconnected fibrils of iron oxyhydroxides, using Mn^(2+) as a morphology regulator. The protocol was based on a microwave-assisted hydrothermal method, using bituminous based activated carbon and both Fe^(2+) and Mn^(2+) ions in the hydrolysis solution. The elemental analysis of modified carbons revealed that Mn does not anchor to the carbon. However, when Mn is included in the hydrolysis solution, the iron content in the activated carbon increased up to 3.5 wt%,without considerable decreasing the adsorbent surface area. Under specific hydrothermal conditions, the Mn^(2+) promoted the formation of iron oxide nanoparticles shaped as interconnected fibrils. This material showed a superior arsenic adsorption capacity in comparison to similar iron modified activated carbons(5 mg As/g carbon, at 2 mg As/L),attributed to the increase in quantity and availability of active sites located on the novel interconnected fibrils of iron oxyhydroxides nanostructures.

关键词： Iron oxide nanostructures Hydrothermal synthesis Microwave Adsorption capacity Kinetics

Reconstructing f(T) modified gravity from ECHDE and ECNADE models

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Communications in Theoretical Physics 2020年第9期72卷 75-88页

作者： A E Godonou Ines G Salako M j S Houndjo Etienne Baffou joel Tossa Institut de Mathematiques et de Sciences Physiques(IMSP) 01 BP 613 Porto-NovoBenin Ecole de Genie Rural(EGR) 01 BP 55 KetouBenin Faculte des Sciences et Techniques de Natitingou(FAST) BP 72NatitingouBenin

We investigate alternative candidates to dark energy(DE) that can explain the current state of the Universe in the framework of the generalized teleparallel theory of gravity f(T), where T denotes the torsion scalar. To achieve this, we carry out a series of reconstructions taking into account the ordinary and entropy-corrected versions of the holographic and new agegraphic DE *** models are used as alternatives to DE in the literature in order to describe the current state of our Universe. It is remarked that the proposed models indicate behavior akin to phantom or quintessence models. Furthermore, we also generate the parameters of the equation of state associated with entropy-corrected models and we observe a phase transition between the quintessence state and phantom state as it is shown by the recent observational data. We also investigate the stability of these models and we create the {r-s} trajectories and compare with the ΛCDM limit. The behavior of certain physical parameters such as the speed of sound and the Statefinder diagnostic pair {r-s} is compatible with the current observational data.

关键词： teleparallel gravity ECHDE ECNADE

Reduced Annealing Time and Enhanced Magnetocaloric Effect of La(Fe,Al)13 Alloy by La-nonstoichiometry and Si-doping

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Acta Metallurgica Sinica(English Letters) 2020年第11期33卷 1535-1542页

作者： Liang Yang jun Li Defang Tu joel C.j.Strickland Qiaodan Hu Hongbiao Dong jianguo Li School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Engineering University of LeicesterLeicester LE17RHUK Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration Shanghai Jiao Tong UniversityShanghai 200240China

LaFe13-x Mx(M=Si,Al)alloys are promising for use in magnetic ***,they require long annealing time(30 days)in order to optimize the magnetocaloric *** has shown that the addition of extra La in off-stoichiometric alloys can greatly shorten the annealing ***,the purpose of this study is to investigate the influence of the extra addition of La on the annealing properties of a new off-stoichiometric La1.7Fe11.6Al1.4-xSix(x=0,0.1,0.4)*** was demonstrated that after a 36 h annealing time,a large volume fraction of 1:13 magnetocaloric phase was obtained for all *** microstructural analysis of the off-stoichiometric La1.7Fe11.6Al1.4-xSix alloys revealed a facet-like grain *** La1.7Fe11.6Al1.4 and La1.7Fe11.6Al1Si0.4 alloys were shown to contain large 1:13 phase precipitates separated in a La-rich matrix,while the La1.7Fe11.6Al1.3Si0.1 alloy had a continuous 1:13 phase matrix with a fine dispersion of La-rich precipitates *** the magnetic field varied between 0 and 2 T,the corresponding magnetic entropy change and relative cooling capacity for the La1.7Fe11.6Al1.3Si0.1 specimen were determined as 4.58 j/kg K and 173.6 j/kg,*** importantly,the La1.7Fe11.6Al1.3Si0.1 alloy displayed only a slight volume change when the meta-magnetic phase transition occurred,which is promising for cyclic use.

关键词： Solidifi cation Magnetic properties Heat treatment Microstructure Functional alloys