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Integrins and their potential roles in mammalian pregnancy

Journal of Animal Science and Biotechnology 2024年第1期15卷 1-19页

作者： Gregory A.Johnson Robert c.Burghardt Fuller w.Bazer Heewon Seo joe w.c.in Department of Veterinary Integrative Biosciences School of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityCollege StationTX 77843‑4459USA Department of Animal Science College of Agriculture and Life SciencesTexas A&M UniversityCollege StationTX 77843‑2471USA

Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(EcM) interactions leading to assembly of integrin adhesion complexes(IAcs) that initiate many signaling functions both at the membrane and deeper within the cytoplasm to coordinate processes including cell adhesion, migration, proliferation, survival, differentiation, and metabolism. All metazoan organisms possess integrins, and it is generally agreed that integrins were associated with the evolution of multicellularity, being essential for the association of cells with their neighbors and surroundings, during embryonic development and many aspects of cellular and molecular biology. Integrins have important roles in many aspects of embryonic development, normal physiology, and disease processes with a multitude of functions discovered and elucidated for integrins that directly influence many areas of biology and medicine, including mammalian pregnancy, in particular implantation of the blastocyst to the uterine wall, subsequent placentation and conceptus(embryo/fetus and associated placental membranes) development. This review provides a succinct overview of integrin structure, ligand binding, and signaling followed with a concise overview of embryonic development, implantation, and early placentation in pigs, sheep, humans, and mice as an example for rodents. A brief timeline of the initial localization of integrin subunits to the uterine luminal epithelium(LE) and conceptus trophoblast is then presented, followed by sequential summaries of integrin expression and function during gestation in pigs, sheep, humans, and rodents. As appropriate for this journal, summaries of integrin expression and function during gestation in pigs and sheep are in depth, whereas summaries for humans and rodents are brief. Because similar models to those illustrated in Fig. 1, 2, 3, 4, 5 and 6 are present throughout the sc

关键词： Humans Implantation Integrins Pigs Pregnancy Rodents Sheep

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crystal reconstruction of V2O3/carbon heterointerfaces via anodic hydration for ultrafast and reversible Mg-ion battery cathodes

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InfoMat 2024年第3期6卷 95-107页

作者： Gun Jang Yun Sang joe Sang Joon Lee Hyun Gyu cho Sang Ha Baek Peixun Xiong Kang Ho Shin Jeong Seok Yeon Min Su Kang Si Hyoung Oh Ho Seok Park School of chemical Engineering Sungkyunkwan University(SKKU)SuwonRepublic of Korea Advanced Batteries Research center Korea Electronics Technology InstituteSeongnamRepublic of Korea Korea Institute of Science and Technology SeoulRepublic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea

Magnesium-ion batteries(MIBs)have promising applications because of their high theoretical capacity and the natural abundance of magnesium ***,the kinetic performance and cyclic stability of cathode materials are limited by the strong interactions between Mg ions and the crystal ***,we demonstrate the unique Mg^(2+)-ion storage mechanism of a hierarchical accordion-like vanadium oxide/carbon heterointerface(V2O3@c),where the V2O3 crystalline structure is reconstructed into a MgV_(3)O_(7)·H_(2)O phase through an anodic hydration reaction upon first cycle,for the improved kinetic and cyclic *** verified by in situ/ex situ spectroscopic and electrochemical analyses,the fast charge transfer kinetics of the V2O3@c cathode were due to the crystal-reconstruction and chemically coupled *** V2O3@c demonstrated an ultrahigh rate capacity of 130.4 mAh g^(-1)at 50000 mA g^(-1)and 1000 cycles,achieving a coulombic efficiency of 99.6%.The high capacity of 381.0 mA h g^(-1)can be attributed to the reversible Mg^(2+)-ion intercalation mechanism observed in the MgV_(3)O_(7)·H_(2)O phase using a 0.3 M Mg(TFSI)2/AcN(H_(2)O)***,within the voltage range of 2.25 V versus Mg/Mg^(2+),the V2O3@c exhibited a capacity of 245.1 mAh g^(-1)when evaluated with magnesium metal in a 0.3 M Mg(TFSI)^(2+)0.25 M Mgcl_(2)/DME *** research findings have important implications for understanding the relationship between the Mg-ion storage mechanism and reconstructed crystal phase of vanadium oxides as well as the heterointerface reconstruction for the rational design of MIB cathode materials.

关键词： anodic hydration reaction magnesium ion battery nano crystal vanadium oxide

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设施作物蒸腾蒸发模型的研究现状及存在问题

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排灌机械工程学报 2024年第1期42卷 57-63页

作者：李迷闫浩芳张川张建云王国庆 AcQUAH Samuel joe 江苏大学国家水泵及系统工程技术研究中心江苏镇江212013 南京水利科学研究院水文水资源与水利工程科学国家重点实验室江苏南京210029 江苏大学农业工程学院江苏镇江212013

确定设施作物蒸腾蒸发量(ET_(c))对于准确制定设施作物灌溉制度、提高设施农业用水效率及设施蔬菜的产量和品质具有重要的意义.对确定设施作物ET_(c)的直接和间接模型进行优缺点及适用性分析,比较了不同类型参考界面蒸腾蒸发(ET_(0))模... 详细信息

确定设施作物蒸腾蒸发量(ET_(c))对于准确制定设施作物灌溉制度、提高设施农业用水效率及设施蔬菜的产量和品质具有重要的意义.对确定设施作物ET_(c)的直接和间接模型进行优缺点及适用性分析,比较了不同类型参考界面蒸腾蒸发(ET_(0))模型的优势与局限性,对比了直接估算温室作物ET_(c)机理模型的准确性,并对不同机理模型中关键参数(冠层阻力参数)的确定方法及主要影响因素进行综述与分析.已有研究主要针对特定气候区域、温室通风类型、作物种类及种植季节,对冠层阻力参数进行修正,并验证模型的准确性,对温室作物ET_(c)模型的普适性研究不够充分,确定的模型参数往往不适用于其他类型温室或作物种植季节.推荐今后重点研究方向:研究温室作物ET_(c)变化过程对气候因子分布特征及变化规律的响应机理;研究不同ET_(c)机理模型对气候类型、作物种类及种植季节的适应性,构建更具普适性的温室作物ET_(c)模型.

关键词：蒸腾蒸发模型温室种类通风气象数据作物种类

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DEGREE 3 ALGEBRAIc MINIMAL SURFAcES IN THE 3-SPHERE

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Acta Mathematica Scientia 2012年第6期32卷 2065-2084页

作者： joe S.wang 4 Ricado Ln St.LauisM063124USA

we give a local analytic characterization that a minimal surface in the 3-sphere S3 c R4 defined by an irreducible cubic polynomial is one of the Lawson＇s minimal tori. This provides an alternative proof of the result by Perdomo （characterization of order 3 algebraic immersed minimal surfaces of S3, Geom. Dedicata 129 （2007）, 23 34）.

关键词： algebraic minimal surface 3-sphere cubic polynomial

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A bipolar verdazyl radical for a symmetric all-organic redox flow-type battery

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Journal of Energy chemistry 2019年第7期28卷 52-56页

作者： Grant D.charlton Stephanie M.Barbon joe B.Gilroy c.Adam Dyker Department of chemistry University of New BrunswickFredericton E3B 5A3New BrunswickCanada Department of chemistry and the centre for Advanced Materials and Biomaterials Research(cAMBR) The University of Western OntarioLondon N6A 5B7OntarioCanada

A symmetric all-organic non-aqueous redox flow-type battery was investigated employing the neutral small molecule radical 3-phenyl-1,5-di-p-tolylverdazyl,which can be reversibly oxidized and reduced in one-electron processes,as the sole charge storage *** voltammetry of the verdazyl radical in 0.5 M tetrabutylammonium hexa fluoro phosphate(TBAPF6)in acetonitrile revealed redox couples at-0.17 V and-1.15 V ***+/Ag,leading to a theoretical cell voltage of 0.98 *** the dependence of peak currents on the square root of the scan rate,diffusion coefficients on the order of 4 x 10 6 cm2 s-1 were *** performance was assessed in a static cell employing a Tokoyuma AHA anion exchange membrane,with 0.04 M verdazyl as catholyte and anolyte in 0.5 M TBAPF6 in acetonitrile at a current density of 0.12 mA *** coulombic efficiencies were good(94%-97%)throughout the experiment,the capacity faded gradually from high initial values of 93%of the theoretical discharge capacity to 35%by the 50th *** and energy efficiencies were 68%and 65%,*** analysis by cyclic voltammetry revealed that decomposition of the active material with cycling is a leading cause of cell degradation.

关键词： All-organic redox flow battery Energy storage Verdazyl radicals Organic radical coin cell

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同好摄影

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天文爱好者 2024年第6期 62-67页

作者：路越(摄影) Yuexiao Shen(摄影) joe Hua(摄影) 吴江(摄影) 李硕(摄影) 刘崴(摄影) 王鑫(摄影) 贺阳(摄影) 李欣然(摄影) 不详

中国空间站凌日时间:2024年3月25日地点:山东省青岛市器材:色球层QHY174MM GPS天文相机,锐星Askar FRA 400/5.6天文望远镜,DayStar Quark(4.2X);光球层PlayerOne Uranus-c(IMX585)相机,锐星SharpStar 107PH APO天文望远镜,SkyRover Solar Herschel wedge。参数:色球层单张曝光0.06ms,增益181:光球层单张曝光0.65ms,增益400,反色处理,补拍日面及日珥后叠加。简介:春分后的太阳躁动不安,巨大的黑子和日珥前,中国空间站悄然划过。

关键词：天文望远镜凌日日面日珥色球层单张

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Machine-learning-facilitated earthquake and anthropogenic source detections near the weiyuan Shale Gas Blocks,Sichuan,china

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Earth and Planetary Physics 2021年第6期5卷 501-519页

作者： Pengcheng Zhou william L.Ellsworth HongFeng Yang Yen joe Tan Gregory c.Beroza MinHan Sheng RiSheng chu Key Laboratory of Ocean and Marginal Sea Geology South China Sea Institute of OceanologyInnovation Academy of South China Sea Ecology and Environmental EngineeringChinese Academy of SciencesGuangzhou 510301China Earth System Science Programme Faculty of ScienceThe Chinese University of Hong KongSha TinHong Kong 999077China Department of Geophysics Stanford UniversityStanfordCA 94305USA State Key Laboratory of Geodesy and Earth’s Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China

Seismic hazard assessment and risk mitigation depend critically on rapid analysis and characterization of earthquake *** seismicity in shale gas blocks of the Sichuan Basin,china,has presented a serious challenge to monitoring and managing the seismicity *** this study,to detect events we apply a machine-learning-based phase picker(PhaseNet)to continuous seismic data collected between November 2015 and November 2016 from a temporary network covering the weiyuan Shale Gas Blocks(SGB).Both P-and S-phases are picked and associated for *** refine the velocity model by using detected explosions and earthquakes and then relocate the detected events using our new velocity *** detections and absolute relocations provide the basis for building a high-precision earthquake *** primary catalog contains about 60 times as many earthquakes as those in the catalog of the chinese Earthquake Network center(cENc),which used only the sparsely distributed permanent *** also measure the local magnitude and achieve magnitude completeness of *** relocate clusters of events,showing sequential migration patterns overlapping with horizontal well branches around several well pads in the wei202 and wei204 *** results demonstrate the applicability of a machine-learning phase picker to a dense seismic *** algorithms can facilitate rapid characterization of earthquake sequences.

关键词： induced seismicity machine learning weiyuan Shale Gas Block

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First-principles study of ferromagnetic metal Fe5GeTe2

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Nano Materials Science 2019年第4期1卷 299-303页

作者： Minwoong joe Unchun Yang changgu Lee School of Mechanical Engineering Sungkyunkwan University2066Seobu-roJangan-guSuwonGyeonggi16419South Korea School of Software Chung-Ang University84Heukseok-roDongjak-guSeoul06974South Korea

For next-generation flexible spin devices,it is crucial to discover and study novel high Tc two-dimensional(2D)magnetic materials considering their atomic-level thickness and flexural mechanical ***,we investigated physical properties of a recently rediscovered ferromagnetic 2D material,Fe5GeTe2,which has near-room temperature Tc,such as stability of monolayer,and electronic and magnetic properties as well as their changes under strain using DFT *** found that monolayer formation energy of Fe5GeTe2 lies inside the energy range of other 2D materials,and thus successful synthesis of the monolayer is *** structures and density of states(DOS)calculations reveal that monolayer Fe5GeTe2 is metallic and of Stoner-type ***,we checked the strain effect on its magnetic *** ferromagnetic(FM)coupling is quite robust under biaxial strain and enhanced significantly with the increase of Fe magnetic moment from 1.65μBto 2.66μBwhile the strain increases from zero to+15%.Such a tunable magnetism of Fe5GeTe2 could provide an extra advantage for flexible magnetic device applications.

关键词： properties. ferromagnetic magnetic

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Molecular cloning and comparative analysis of transcripts encoding chemosensory proteins from two plant bugs, Lygus lineolaris and Lygus hesperus

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Insect Science 2020年第3期27卷 404-424页

作者： J.joe Hull Omaththage P.Perera Mei-Xian wang USDA-ARS Arid Land Agricultural Research center MaricopaArizonaUSA USDA-ARS Southern Insect Management Research UnitStonevilleMississippiUSA college of Animal Sciences Zhejiang UniversityHangzhouChina

chemosensory proteins(cSPs)are soluble carrier proteins typically characterized by a six‐helix bundle structure joined by two disulfide bridges and a conserved cys spacing pattern(c1‐X6‐8‐c2‐X16‐21‐c3‐X2‐c4).cSPs are functionally diverse with reported roles in chemosensation,immunity,development,and *** expand our molecular understanding of cSP function in plant bugs,we used recently developed transcriptomic resources for Lygus lineolaris and Lygus hesperus to identify 17 and 14 cSP‐like sequences,*** Lygus cSPs are orthologous and share significant sequence identity with previously annotated *** of the cSPs are predicted to deviate from the typical cSP structure with either five or seven helical segments rather than *** seven helix cSP is further differentiated by an atypical c3‐X3‐c4 cys spacing *** transcriptase PcR‐based profiling of cSP transcript abundance in adult *** tissues revealed broad expression for most of the cSPs with antenna specific expression limited to a subset of the *** sequence analyses and homology modeling suggest that variations in the amino acids that comprise the Lygus cSP binding pockets affect the size and nature of the ligands accommodated.

关键词： chemosensation chemosensory protein homology modeling Lygus plant bug mired transcriptome

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Fatigue and Quality of Life of women Undergoing chemotherapy or Radiotherapy for Breast cancer

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clinical oncology and cancer researeh 2009年第3期6卷 179-185页

作者： winnie K.w.So Gene Marsh w.M.Ling F.Y.Leung joe c.K.Lo Maggie Yeung George K.H.Li Department of Nursing Studies The University of Hong Kong School of Nursing University of Colorado Health Science Center Nurse Specialist Department of Clinical OncologyPamela Youde Nethersole Eastern Hospital Infection control Unit Princess Margaret Hospital Oncology Department Princess Margaret Hospital clinical Oncology Department Tuen Mun Hospital Department of Surgery Queen Mary Hospital

OBJEcTIVE To examine fatigue and quality of life (QOL) inbreast cancer patients undergoing chemotherapy or *** A self-report survey derived from the chineseversion of Brief Fatigue Inventory, the Functional Assessmentof chronic Illness Therapy for Breast cancer, and the MedicalOutcomes Study Social Support Survey. Descriptive statisticswas used to examine the intensity of fatigue and the prevalenceof severe fatigue. Multivariate analysis of variance was used todetermine factors that affect the five domains of QOL among *** The majority of the participants (n = 261) perceiveda mild level of fatigue, but 35.6% of them suffered severe *** had a significantly negative association with all domainsof QOL except social/family wellbeing. The participants whowere receiving chemotherapy, undergoing curative treatment andhaving inadequate social support were more likely to have poorerQOL in all five domains (after adjustment for age).cONcLUSION Although the majority of the participantsexperienced a mild level of fatigue, there was a substantial groupof breast cancer patients who perceived their fatigue as severe. Thefindings of this study showed that fatigue had a detrimental effecton the various aspects of the participants' QOL. Demographic andclinical characteristics of breast cancer patients who were at riskof getting poorer QOL were identified. The results of the studydemonstrate that we should enhance healthcare professionals'awareness of the importance of symptom assessment, andprovide them with information for planning effective symptom-management strategies among this study population.

关键词： breast neoplasm fatigue quality of life drug therapy.

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