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Open Journal of Endocrine and Metabolic Diseases 2023年第2期13卷 39-44页

作者： Yao Assita Lecadou jocelyne Maman Salahoudine N’guessan Anselme danho jocelyne Kouassi Frank Hué Adélaïde Koffi Dago Pierre Abodo Jacko Endocrinology Diabetology Department CHU Yopougon Abidjan Ivory Coast

Introduction: The curative management of primary hyperparathyroidism is based on surgery. We report the case of a patient presenting with elevated parathormone despite surgical removal of the parathyroid adenoma. Observation: A 48-year-old patient presented for more than 6 months with significant weight loss, polyuria with polydipsia and impaired renal function. The assessment carried out revealed hypercalcaemia at 155 mg/L with hypophastetaemia at 24 mg/L and an elevation of the parathyroid hormone at 218.9 pg/ml. Cervical ultrasound showed a mass at the expense of the lower left parathyroid gland. These results made it possible to conclude primary hyperparathyroidism by parathyroid adenoma which was supported surgically. The postoperative biological assessment revealed a normocalcemia at 85 mg/L associated with an increase in parathormone (PTH) at 271.9 pg/ml. In front of the normalization of calcemia in the subsequent controls and the amendment of all the signs, monitoring was carried out. 9 months after surgery, spontaneous normalization of PTH was observed at 38.4 pg/ml with normal serum calcium at 90 mg/l. Discussion: Primary hyperparathyroidism can be revealed by other manifestations. Post-operative follow-up is generally simple with normalization of PTH and serum calcium. However, there may persist an elevation of PTH with normal self-limiting calcemia.

关键词： Primary Hyperparathyroidism Postoperative Follow-Up Normocalcemic Hyperparathormonemia

Glycemic Responses of Food Formulations Based on White Rice and White Bean

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Food and Nutrition Sciences 2023年第3期14卷 225-232页

作者： Assita Yao Jean-Brice Gbakayoro Cyrille Tan Anselme N’guessan jocelyne danho Frank Kouassi Adélaïde Hué Pierre Koffi-Dago Mory Traoré Salahoudine Maman Jacko Abodo Albarin Gbogouri Service d’Endocrinologie Diabétologie du CHU de Yopougon Abidjan Côte d’Ivoire Laboratoire de Nutrition et Sécurité Alimentaire Université Nangui Abrogoua Abidjan Côte d’Ivoire

The management of diabetes mellitus is based on lifestyle and dietary measures suggesting the consumption of foods with a low glycemic index. The present study was conducted in order to propose food formulas based on white rice and white beans resulting in a lower glycemic response. For this, food formulations based on these foods were first made, in particular the formulation [75% white rice + 25% white beans] and the formulation [50% rice + 50% white beans]. Then, the biochemical composition of white rice, white bean and these two formulations was determined by the usual methods. Finally, their glycemic responses over 120 minutes were studied by the FAO/ WHO 1998 method. The results showed that white rice [100% white rice] had the highest carbohydrate content (54.61%) followed respectively by the formulation [75% white rice + 25% white bean] (45.69%), the white bean [100% white bean] (29.1%) and the formulation [50% white rice + 50% white bean] (26.16%). In terms of glycemic responses, the formulation [50% white rice + 50% white beans] presented the best evolution with a lower peak (6.041 mmol/L) observed at T45min and a lower postprandial glycemia (4.872 mmol/ L) at T120min. An increase in the proportion of beans is therefore recommended as it may suggest a beneficial metabolic effect.

关键词： White Rice White Bean Food Formulation Glycemic Response

Modulation of Postprandial Glucose Bioavailability in a Cohort of Healthy and Pre-Diabetics Subjects during Ramadan Fasting in cote d'Ivoire

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Open Journal of Endocrine and Metabolic Diseases 2017年第5期7卷 127-139页

作者： Jacko R. Abodo Jean B. Gbakayoro Kouakou Brou Georges G. Tiahou Adélaide Hué Assita Yao jocelyne danho Adrien Lokrou Office of Endocrinology Diabetes Nutrition CHU Yopougon Abidjan cote d'Ivoire Laboratory of Nutrition and Food Safety Faculty of Science and Food Technology University Nangui Abrogoua Abidjan cote d'Ivoire Laboratory of Biochemistry Medical Sciences Faculty University Alassane Ouattara Bouaké cote d'Ivoire

Objective: After the Ramadan fasting period, there is an increasing prevalence of diabetes in Cote d’Ivoire, in diabetes care centers. The objective of this study was to assess the consumption of sugary foods during this period and to determine the risks of diabetes in Muslim populations. Methods: Information was collected on the type and amount of sugary foods consumed. Methods for the preparation of these foods have been determined. Intake frequencies and postprandial glycemic responses were studied. The usual statistical methods were used. Results: Between 70% and 85% of the “fasters” consume plenty of these sugary foods during this period, with an average added sugar level varying between 10% and 35% and a daily consumption of between 250 cl and 0.5 l. The added sugar leads to hyperglycemia in both healthy subjects and pre diabetics. Conclusion: Regular consumption of these sugary foods results in significant hyperglycaemia throughout the month of fasting with a significantly higher blood glucose level in pre diabetic subjects. This makes pre diabetics people more at risk of diabetes among Muslim populations during Ramadan fasting.

关键词： Ramadan Fasting Postprandial Glucose Pre Diabetes

Typology and Etiology of Precocious Puberty in Sub-Saharan Africa:Report of 8 Cases in Abidjan,Ivory Coast

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Advances in Sexual Medicine 2017年第4期7卷 161-166页

作者： Jacko R.Abodo Laurette Agbré-Yacé Adélaide Hué Ténédia Soro-Coulibaly Micondo Kouamé Mamadou Sanogo jocelyne danho Jean B.Ahoussi Adrien Lokrou Department of Endocrinology-Diabetology University Hospital YopougonAbidjanCote d’Ivoire Pediatric Endocrinology Unit National Institute of Public HealthAbidjanCote d’Ivoire Department of Pediatrics General Hospital of Abobo NordAbidjanCote d’Ivoire Pediatric Service Military Hospital of AbidjanAbidjanCote d’Ivoire

Introduction: Early puberty is defined by development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. In the West, one in five children out of 100,000 is concerned. Little information on sub-Saharan African patients exists concerning this pathology. Objective: To determine the etiology and clinical characteristics of early puberty in a cohort of Ivorian children. Methods: We conducted a cross-sectional study between 2015 and 2017 in children admitted to early puberty in the unique Endocrinology Service of the country. The epidemiology and clinical characteristics were assessed. Results: The eight patients involved were all females. Their mean age at diagnosis was 7 years and 3 months and the mean age of first symptoms begun at 5 years and 6 months. Seven patients had a central precocious puberty (CPP) including five cases of idiopathic CPP (ICPP) treated by (GnRH agonist) and two cases with secondary precocious puberty (SPP). One of them has a hypothalamic hamartoma and the other a sequelae of encephalopathy. The last case had a peripheral precocious puberty (PPP) causes by ovarian dystrophy. Conclusion: Our results confirm the predominance of idiopathic central precocious puberty particularly in girls.

关键词： Early Puberty Secondary Sexual Characteristics Stature