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Multiband mucosectomy for advanced dysplastic lesions in the upper digestive tract

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World Journal of Gastrointestinal Endoscopy 2015年第4期7卷 370-380页

作者： Jesús Espinel Eugenia Pinedo Vanesa Ojeda Maria Guerra del rio Department of Digestive Diseases Hospital Universitario de León Department of Radiodiagnosis Hospital Universitario de León Department of Digestive Diseases Hospital Universitario Dr.NegrínLas Palmas de Gran Canaria35010 Spain Burton Hospitals NHS Foundation Trust Burton on Trent

Endoscopic resection(ER) is at present an accepted treatment for superficial gastrointestinal neoplasia. ER provides similar efficacy to surgery; however, it is minimally invasive and less expensive. Endoscopic mucosal resection(EMR) is superior to biopsy for diagnosing advanced dysplasia and can change the diagnostic grade and the management. Several EMR techniques have been described that are alternatively used dependent upon the endoscopist personal experience, the anatomic conditions and the endoscopic appearance of the lesion to be resected. The literature suggests that EMR offers comparable outcomes to surgery for selected indications. EMR techniques using a cap fitted endoscope and EMR using a ligation device [multiband mucosectomy(MBM)] are the most frequently use. MBM technique does not require submucosal injection as with the endoscopic resectioncap technique, multiple resections can be performed with the same snare, pre-looping the endoscopic resection-snare in the ridge of the cap is not necessary, MBM does not require withdrawal of the endoscope between resections and up to six consecutive resections can be performed. This reduces the time and cost required for the procedure, while also reducing patient discomfort. Despite the increasing popularity of MBM, data on the safety and efficacy of this technique in upper gastrointestinal lesions with advanced dysplasia, defined as those lesions that have high-grade dysplasia or early cancer, is limited.

关键词： Endoscopic mucosal resection Barrett'sesophagus Esophageal cancer Early gastric cancer Stepwise radical endoscopic resection Multibandmucosectomy Endoscopic submucosal dissection

膝关节软骨的评估:常规MR成像方案加扫T2图序列的价值

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国际医学放射学杂志 2013年第4期 371-372页

作者： R. Kijowski D.G. Blankenbaker A.M. del rio G.S. Baer B.K. Graf 范翔 Department of Radiology University of Wisconsin School of Medicine and Public Health 600 Highland Ave Clinical Science Center-E3/311Madison WI 53792-3252

目的确定3.0T膝关节常规MR成像方案加扫T2图序列能否提高对关节软骨损伤的诊断性能。材料与方法本项前瞻性研究经机构审查委员会批准,并免除知情同意书。研究组包括行膝关节MR成像及关节镜检查的病人150例(男76例,女74例,平均年龄分别为... 详细信息

目的确定3.0T膝关节常规MR成像方案加扫T2图序列能否提高对关节软骨损伤的诊断性能。材料与方法本项前瞻性研究经机构审查委员会批准,并免除知情同意书。研究组包括行膝关节MR成像及关节镜检查的病人150例(男76例,女74例,平均年龄分别为41.2岁和41.5岁)。MR成像应用常规扫描方案并加扫矢状位T2图序列在3.0TMR设备上完成。手术前由2位放射科医生回顾所有MR影像并达成意见一致,确定每个关节面是否存在软骨损伤,首先仅阅读常规MR影像,之后再阅读常规MR影像加T2图。然后应用关节镜对每个关节软骨表面进行评估。利用广义估计方程模型,评估上述两种方法检测关节软骨损伤的敏感性和特异性。结果单独应用常规MR检查方案检测351处软骨损伤的敏感度与特异度分别为74.6%和97.8%,而常规MR检查方案加扫T2图的敏感度与特异度分别为88.9%和93.1%。敏感度与特异度的差异有统计学意义(P<0.001)。加扫T2图序列可显著提高检测关节软骨病变的敏感度,其中包括24处软骨软化的区域(从4.2%升至62%,P<0.001)、41处软骨纤颤的区域(从20%升至66%,P<0.001)及96处表面局部增厚的软骨缺损(从71%升至88%,P=0.004)。结论 3.0TMR常规检查方案加扫T2图序列可提高检测膝关节软骨病变的敏感度,由74.6%升至88.9%,特异度略降低。加扫T2图序列对鉴别早期软骨退变的敏感度提升最为显著。

关键词： MR 检查方案特异度敏感度膝关节软骨图序列 T2 常规

控制停车场系统使用LabView和个人电脑并行端口

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电子设计技术 EDN CHINA 2008年第9期15卷 106-106,108,109页

作者： Unidad sede San Luis rio Colorado Centro de Estudios Superiores del Estado de Sonora Carlos Alberto Aguilar Sández Sonora Mexico Unidad sede San Luis rio Colorado

在本设计实例中．电路控制停车场的进出车辆。本项目将National Instruments（美国国家仪器有限公司）的LabView作为主要编程工具，并将个人电脑的并行端口作为输入／输出端口。电路的核心是将个人电脑的状态端口379h用作传感器的输入... 详细信息

在本设计实例中．电路控制停车场的进出车辆。本项目将National Instruments（美国国家仪器有限公司）的LabView作为主要编程工具，并将个人电脑的并行端口作为输入／输出端口。电路的核心是将个人电脑的状态端口379h用作传感器的输入端，并用继电器将其隔离以防止破坏个人电脑（图1）。在数据端13378h，D0位控制出入口，D1是停止信号，D2是通行信号，D3表示停车场满位。所有信号都驱动带有一个外部电源的PN2222A晶体管．在这种情况下，外部电源是个人电脑的电源。这样，可以将继电器作为负载并控制交通灯和出入口电机的交流电压。D0驱动的晶体管控制双极／双投（DPDT）继电器以转化电机的极性。

关键词： LabView 电路控制个人电脑并行端口停车场美国国家仪器有限公司输入/输出端口

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精氨酸酶-内皮型一氧化氮合酶失衡促进慢性间歇性缺氧期间的内皮功能障碍

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中华高血压杂志 2015年第5期23卷 469-469页

作者：刘莉叶鹏 Krause BJ del rio R Moya EA Marquez-Gutierrez M Casanello P Iturriaga R

慢性间歇性缺氧（chronic intermittent hypoxia，CIH）是阻塞性睡眠呼吸暂停的主要特征，与血管功能损害相关，尽管其不会改变血管对一氧化氮供体的反应。该研究旨在探讨精氨酸酶是否促进CIH大鼠血管内皮功能障碍。

关键词：血管内皮功能障碍慢性间歇性缺氧内皮型-氧化氮合酶精氨酸酶缺氧期阻塞性睡眠呼吸暂停失衡一氧化氮供体

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为快速ADC提供电压箝位与DC偏置模拟电路

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电子设计技术 EDN CHINA 2008年第7期15卷 102-102页

作者： Alfredo del rio University of Vigo

许多快速ADC都推荐0.6V-2.6V输入电压范围，如美国国家半导体公司的ADC1175（参考文献1）。但在某些应用中，必须要转换一个对称的模拟输入信号。本设计实例中的电路将一个-0．2V－＋0．2V范围的对称输入电压转换到推荐的0．6V－2．6V... 详细信息

许多快速ADC都推荐0.6V-2.6V输入电压范围，如美国国家半导体公司的ADC1175（参考文献1）。但在某些应用中，必须要转换一个对称的模拟输入信号。本设计实例中的电路将一个-0．2V－＋0．2V范围的对称输入电压转换到推荐的0．6V－2．6V范围（图1）。该电路亦能防止输出电压低于-0.3V，以防止损坏ADC。

关键词：模拟电路电压范围 ADC 美国国家半导体公司偏置箝位输入信号参考文献

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Comparative Studies of <i>Bacillus thuringiensis</i>var. </i>israelensis</i>Metabolism in Different Concentrations of Cassava Flour Processing Waste Based Media

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Advances in Bioscience and Biotechnology 2014年第12期5卷 978-983页

作者： Samara Ernandes Vanildo L. del Bianchi Iracema O. Moraes Universidade Tecnológica Federal do Paraná (UTFPR) Dois Vizinhos Brasil Universidade Estadual Paulista (UNESP) S&atildeo José do Rio Preto Brasil Probiom Tecnologia Indústria e Comércio de Bioprodutos LTDA Campinas Brasil

Techniques of production of enthomopatogenic bacteria are developed aiming to increase the productivity and to reduce the costs of the fermentative process. Like this, it has been using agroindustrial wastes or by-products as nutrient sources in culture medium, having been used, in this study, the manipueira, a by-product of the processing of the cassava flour. Fermentations were performed in flasks of Erlenmeyer of 500 mL containing 250 mL of culture media, conditioned in shaker at 180 r.p.m. and 28°C, and the media were composed by manipueira, in concentrations that varied between 400 and 1000 mL/L. The time of the process varied between 48 and 120 hours. They appraised the following parameters: cellular growth, the production of spores, the reduction of organic matter (COD analysis) and the variation of reduction sugar. Although there was a proportional cellular growth to the manipueira concentration, the production of spores was similar in all the cases, at the end of the process, in spite of the smallest speed of production of the same ones in the highest concentrations. In relation to the variation of COD, it has, also, a percentile minor of reduction in the highest concentrations. In the analysis of variation of reduction sugars, the higher concentrations are the ones that they present larger slowness in the reduction of this.

关键词： Bioinsecticides Agroindustrial Wastes Bacillus thuringiensis var. israelensis Fermentation

Occupational Stress versus Cortisol Associated with Psychological Variables and Gender Differences among Women and Men in Nursing

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Health 2015年第7期7卷 838-846页

作者： Virginia Dresch María del Pilar Sánchez-López Ana Isabel Saavedra EPSY-Research Group Psychological Styles Gender and Health Madrid Spain Red Hygeia—Health & Gender International Alliance Madrid Spain Universidade Federal Fluminense Rio de Janeiro Brazil Universidad Complutense de Madrid Madrid Spain Hospital Universitario de Getafe Madrid Spain

The present research focused on a sample of Spanish male and female nurses to determine whether psychological variables are related to occupational stress and cortisol. Spanish male (n = 98) and female (n = 98) nurses, matched in diverse sociodemographic variables, completed measures of occupational stress, cortisol 8 am (8 h), and cortisol 8 pm (20 h), and psychological variables. Multivariable regression analyses revealed different patterns of association among the variables when analyzing subjective and (occupational stress) objective indicators (cortisol at 8 h and cortisol at 20 h). In male nurses, higher stress is related to worse self-perceived health, worse mental health, less cortisol measured at 8 h, and more morningness. For the female nurses, higher stress is related to being younger, worse self-perceived health, and less job satisfaction. The only similarities found in the target variables and the measures of stress studied in the groups of males and females are worse self-perceived health and worse mental health associated with more occupational stress.

关键词： Occupational Stress Cortisol Health Nursing Spain

CT结肠成像扁平息肉表面的对比剂涂层:病变的检出标记

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国际医学放射学杂志 2014年第3期 305-306页

作者： D.H.Kim J.L.Hinshaw M.G.Lubner A.Munoz del rio B.D.Pooler P.J.Pickhardt 唐光健 Department of Radiology University of Wisconsin Medical SchoolE3/311 Clinical Science Center 600 Highland Ave.MadisonWI 53792-3252USA

摘要目的评价扁平息肉在口服对比剂时涂层的出现率,此征象可能提高病变的检出,成为CT结肠成像(CTC)筛查的影响因素。方法本回顾性观察研究于单一机构内进行。

关键词：扁平息肉结肠成像涂层检出对比剂病变 CT

CT结肠成像中各种类型锯齿状息肉的发生率及特征

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国际医学放射学杂志 2016年第5期 572-573页

作者： D.H.Kim K.A.Matkowskyj M.G.Lubner J.L.Hinshaw A.Munoz del rio B.D.Pooler 杨学东 Department of Radiology University of Wisconsin School of Medicine and Public Health E3/311 Clinical Science Center

摘要目的描述大规模、一般风险人群CT结肠成像筛查所见的结肠锯齿状息肉的发生率及特征。方法本回顾性研究符合HIPAA,经威斯康辛大学医学和公共卫生学院伦理委员会批准,免除知情同意书。纳入8 289例共9 600次单中心CT结肠成像(2004年—2... 详细信息

摘要目的描述大规模、一般风险人群CT结肠成像筛查所见的结肠锯齿状息肉的发生率及特征。方法本回顾性研究符合HIPAA,经威斯康辛大学医学和公共卫生学院伦理委员会批准,免除知情同意书。纳入8 289例共9 600次单中心CT结肠成像(2004年—2011年),评价非小锯齿状病变和

关键词：结肠成像锯齿状息肉发生率 CT