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Evaluation of the Size and Location of the Genial Plexus,Related to Age,Sex and dental Presence,in Implant Surgeries

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Journal of Biomedical Science and Engineering 2017年第10期10卷 456-465页

作者： joao Henrique Scotti Alerico Neuza Maria souza Picorelli Assis Carlos Eduardo Francischone Karina Lopes devito Francisco Antoninho Alerico Bruno Salles Sotto-Maior department of Implantology Sao Leopoldo Mandic Dental Research CenterSao LeopoldoBrazil department of dental Clinic Federal University of Juiz de ForaJuiz de ForaBrazil department of Diagnosis Paranaense UniversityFrancisco BeltraoBrazil department of Restorative dentistry Federal University of Juiz de ForaJuiz de ForaBrazil

Generally being considered as a safe area for surgical approaches, the region between the mental foramina presents important anatomical structures. The objective of this study was to measure the dimensions of the genial plexus and its three-dimensional location in CBCT images, correlating the characteristics of this structure with dental presence, sex and age of patients. A total of 149 cone beam computer tomography (CBCT) scans of dentate (n = 74) and edentulous patients (n = 75) were selected, 59 male and 90 female, aged 18 - 86 years. Measurements of width and length of the genial canal were performed, and the shortest distances of the genial plexus were determined in relation to the alveolar bone crest, the buccal cortical bone and the base of the mandible. The results indicated significant differences between the dentate and edentulous groups for the mandibular canal length (p = 0.030), distance from alveolar crest (p dentate patients. As for gender, the distances between the genial plexus and the alveolar bone crest (p der patients. It can be concluded that there are variations of the genial plexus in relation to gender, age and between edentulous and dentate patients. Therefore, the anterior region of the mandible, especially the midline should be observed with caution when undergoing surgical procedures, such as removal of bone grafts and installation of dental implants.

关键词： Genial Canal Cone-Beam Computed Tomography dental Implants Measurement Paresthesia

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Prevalence of Family History of Cancer among Gastric Cancer Patients at Brazilian National Cancer Institute

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Health 2017年第1期9卷 25-37页

作者： Tamara Figueiredo Maria Teresa Santos Guedes Luis Paulo souza e souza Antonio Abílio Santa Rosa Antonio Carlos Accetta Maria Aparecida de Luca Nascimento Lais Santiago deivite Danilo Ferreira Alcantara department of Postgraduate in Adult Health Federal University of Minas GeraisBelo HorizonteBrazil department of Radiotherapy Health Foundation Dilson de Quadros GodinhoMontes ClarosBrazil National Tumor/DNA Bank National Cancer Institute Rio de JaneiroBrazil department of Postgraduate Course in Nursing and Biosciences Federal University of Rio de Janeiro StateRio de JaneiroBrazil department of Postgraduation in Public Health Federal University of Minas GeraisBelo HorizonteBrazil department of Medicine Federal University of Sao Joao del ReiSao Joao del ReiBrazil Research department of the Bonsucesso General Hospital Ethics Committee National Cancer InstituteRio de JaneiroBrazil department of Abdominal-Pelvic Surgery National Cancer InstituteRio de JaneiroBrazil department of Chemotherapy National Cancer InstituteRio de JaneiroBrazil

Background: Gastric cancer is the third most incident malignancy and the fifth leading cause of death in the world. In Brazil, it is the fourth most common tumour in men and the fifth in women. Familial aggregation of this tumour is being studied and discussed by experts. Aim: determine the frequency of family history of cancer in patients with gastric cancer, suggesting familial aggregation or increased risk for hereditary cancer syndromes. Methods: This is a retrospective cross-sectional study carried out from January 2011 to March 2015 at the department of Abdominal and Pelvic Surgery of the Brazilian National Cancer Institute (INCA). Data were collected from electronic medical records and analyzed using SPSS Statistics? version 20. Results: 873 patients with gastric adenocarcinoma were analyzed. A family history of cancer was reported by 451 patients (51.6%), which reported cancer in 878 relatives, of which 110 (12.6%), reported having more than three relatives with any type of cancer. The most prevalent malignancies among these relatives were gastric cancer (21.3%) and breast cancer (9.5%). Conclusion: Most of the patients had cancer family history, being gastric cancer the most common. The high percentage of cancer family history confirms the importance of collecting this information, whose lack reflects professional negligence, as family history study can serve as a low-cost tool, favoring prevention and early diagnosis, situations where morbidity and mortality are smaller, thus reducing health costs and assistance and preserving lives.

关键词： Stomach Neoplasms Family History Hereditary Aggregation Hospital Records Cross-Sectional Studies

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Punica granatum Leaf Lipophilic Fraction Favours Mortality by Attenuating Inflammation in Mice with Polymicrobial Sepsis

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Journal of Pharmacy and Pharmacology 2019年第7期7卷 355-367页

作者： Nagila Caroline Fialho Sousa Isabella Fernandes da Silva Figueiredo Mizael Calacio de Araujo Elaine Pereira de Andrade Thais Costa Alves Bruna Letícia Rosa da Silva Domingos Magno Santos Pereira Saulo JoseFigueiredo Mendes joao Francisco Silva Rodrigues Jaqueline Pessoa Pontes Simone Aparecida Teixeira AndreAlvares Marques Vale Marcus Vinicius Dias-souza Lidio Goncalves Lima-Neto Vera Lucia dos Santos Ana Paula Azevedo-Santos Marcelo Nicolas Muscara Valerio Monteiro-Neto Andrea de souza Monteiro Luis Claudio Nascimento da Silva Elizabeth Soares Fernandes Programa de Pos-graduacao Universidade CEUMARua JosueMontellon°1RenascencaSao LuisMA 65075-120Brazil departamento de Farmacologia Universidade de Sao PauloAv.Prof.Lineu Prestesn°1524Sala 326ButantanSao PauloSP 05508-900Brazil Programa de Pos-graduacao em Ciências em Saude Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuisMA 65080-805Brazil departamento de Microbiologia Universidade Federal de Minas GeraisAv.Antonio Carlosn°6627PampulhaBelo HorizonteMG 31270-901Brazil departamento de Patologia Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuísMA 65080-805Brazil

Punica granatum *** known antimicrobial and anti-inflammatory *** of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have supported the use of *** extracts for this ***,little is known of the effects of ***-derived fractions in severe infectious diseases such as ***,we investigated the actions of the hexane fraction(HF),rich in lipophilic compounds,obtained from the leaves of this plant,in a murine model of polymicrobial *** pre-treatment with HF increased mortality in septic *** same animals presented with lower levels of interleukin-6,nitric oxide and hydrogen peroxide in their peritoneal lavage samples than vehicle *** also increased polymorphonuclear cell accumulation in to the peritoneum of mice with ***-derived nitric oxide upon lipopolysaccharide stimuli was markedly reduced by incubation with ***,triterpenes,phytosterols,vitamin E and ascorbyl palmitate were detected in the *** results indicate that *** leaf lipophilic fractions may worsen sepsis *** effect may be associated with its bioactive compounds which act synergistically or not,increasing sepsis mortality in vivo.

关键词： P.granatum infection inflammation

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Characterization of the Biological Potential of the Essential Oils from Five Species of Medicinal Plants

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American Journal of Plant Sciences 2017年第2期8卷 154-170页

作者： Danubia Aparecida Carvalho Selvati Rezende Rafaela Vieira souza Maisa Lamounier Magalh?es Alex Rodrigues Silva Caetano Marcos Schleiden Sousa Carvalho Ellen Cristina de souza Luiz Gustavo de Lima Guimaraes David Lee Nelson Luís Roberto Batista Maria das Gra?as Cardoso departamento de Química Universidade Federal de LavrasLavrasBrasil departamento de Ciencia dos Alimentos Universidade Federal de LavrasLavrasMGBrasil departamento de Ciência dos Alimentos Universidade Federal de LavrasLavrasMGBrasil departamento de Agricultura Universidade Federal de LavrasLavrasMGBrasil Universidade Federal de Sao joao del-Rei Sao Joao del-ReiBrasil Universidade Federal do Vale do Jequitinhonha e Mucuri DiamantinaMGBrasil

Essential oils from Mentha piperita, Cymbopogon citratus, Rosmarinus officinalis, Peumus boldus and Foeniculum vulgare were extracted by hydrodistillation, chemically characterized and quantified by GC/MS and GC/FID. The principal componentes in the essential oil of M. piperita (carvone and limonene), C. citratus (geranial, neral and myrcene), R. officinalis (1,8-cineole, camphor and α-pinene), P. boldus (α-terpinyl formate, p-cymene and 1,8-cineole) and F. vulgare (methyl chavicol, limonene and fenchone) were identified. The oils were tested for antioxidant activity employing the DPPH (2,2-diphenyl-1-picryl-hydrazyl) radical-capture method, the oxidation of the β-carotene/linoleic acid system, and the ABTS radical-capture method. The essential oils were not effective. The antioxidant activities of the oils were determined by the hydroxyl method, and the highest activity (62.80%) was observed with the essential oil from M. piperita. Activities of 1.54 and 1.82 μg μg-1, respectively, were observed for the essential oils from C. citratus and P. Boldus using the phosphomolybdenum method. No activity was observed with respect to reducing power. The essential oil from C. citratus was effective in inhibiting the growth of L. monocytogenes (15.63 mg·L-1), S. choleraesuis (15.63 mg·L-1) and E. coli (31.25 mg·L-1), and the essential oil from P. boldus inhibited the growth of S. aureus (62.5 mg·L-1). No essential oil inhibited the growth of P. aeruginosa. A low antioxidant activity and a promising antibacterial activity were observed for these essential oils.

关键词： Natural Products Antioxidant Antibacterial Activity

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Study of the Positioning Influence in the Water Activity Measurement during Leak Test of Iodine-125 Seeds

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Journal of Physical Science and Application 2015年第5期5卷 345-348页

作者： joao A. Moura Anselmo Feher Carlos A. Zeituni Maria E. C. M. Rostelato Wilson A. P. Calvo Oswaldo L.Costa Carla D. souza Dib K. Junior Anderson R. Camargo Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN- SP) Av. Professor Lineu Prestes 2242 05508-000 Sao Paulo SPBrazil Universidade de Sao Paulo (USP Leste) Rua Arlindo Bettio 1000 03828-000 Sao Paulo SP Brazil Faculdade de Tecnologia de Sorocaba departamento de Mecanica Av. Engenheiro Carlos Reinaldo Mendes 2015 18013-280 Sorocaba - SP Brazil

In the prostate cancer treatment, brachytherapy with iodine-125 seeds has been used. lodine-125 seeds are sealed radioactive sources, made by a titanium capsule containing the radioisotope inside. In the final phase of the seeds production, it is necessary to ensure that there is no leakage of the radioactive material. A leakage test is performed, immersing the seeds in water during 24 h and measuring the resulting activity in the water. This measurement is made in a sodium iodide detector. The immersion water is transferred to a plastic tube with a cap. The tube is placed by an automated positioning system, in the detector chamber. This study aims to determine the best positioning of the tube for the detection. It is also important to determine the influence of the positioning variation intrinsic of the automated positioning system during the iodine-125 seeds production. The results obtained will be used as a reference to adjust the equipment and process control system, in the production of the iodine-125 seeds.

关键词： Iodine-125 seeds brachytherapy prostate cancer treatment leakage immersion test automated positioning system.

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Epidemiology and Clinical Features of Mycobacterium avium Complex Pulmonary Disease in a Brazilian Amazon Cohort

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Advances in Microbiology 2024年第6期14卷 287-302页

作者： Jose Tadeu Colares Monteiro Adriana Rodrigues Barretto Ruan Seguin Azevedo Quaresma Bianca Miranda Gouveia Ismari Perini Furlaneto Victória Menezes da Costa Yan Corrêa Rodrigues Layana Rufino Ribeiro Ricardo J. de Paula souza e Guimarães Alex Brito souza Ana Roberta Fusco da Costa Karla Valéria Batista Lima joao de Barros Barreto University Hospital Federal University of Par Belm Brazil Center for Biological and Health Sciences Ph.D. Program in Parasitic Biology in the Amazon Region (PPGBPA) State University of Par (UEPA) Belm Brazil department of Medicine Centro Universitrio do Par CESUPA Belm Brazil Bacteriology and Mycology Section Evandro Chagas Institute (SABMI/IEC) Ministry of Health Ananindeua Brazil Geoprocessing Laboratory Evandro Chagas Institute/SVSA/MS Ananineua Brazil

The incidence of Mycobacterium avium complex pulmonary disease (MACPD) has been globally increasing. The present study aims to provide a comprehensive analysis of clinical characteristics and treatment response among patients in the Amazon region of Brazil and conduct a retrospective cohort study at a prominent referral hospital in the State of Par, Brazil, from 2012 to 2020. The M. avium group represented 58.9% of cases, followed by M. intracellulare (35.7%), M. colombiense (3.6%), and M. chimaera (1.8%). The majority of patients (73.2%) were female and with an average age of 63 years. Primary clinical manifestations included persistent cough and sputum production. The Charlson comorbidity index (CCI) averaged 2.47, with 36.3% of patients having a CCI score equal to higher than 3. Notably, over 70% of patients had received treatment for pulmonary tuberculosis before initiating treatment for MAC infection. The fibrocavitary radiologic form was the most prevalent (55.4%), frequently exhibiting a bilateral distribution (53.6%). Antimicrobial susceptibility revealed a significant prevalence of MAC resistance to drugs in the therapeutic regimen. despite this, most of the patients experienced clinical improvement (50%). In conclusion, this study highlights a higher prevalence of MAC infections among middle-aged women, with a history of pulmonary tuberculosis treatment and presenting the fibrocavitary radiological form was predominant.

关键词： MACDP Nontuberculous Mycobacteria Mycobacterium avium Lung Disease

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Essential Oils from the Leaves and Flowers of Callistemon viminalis:Chemical Characterization and Evaluation of the Insecticide and Antifungal Activities

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American Journal of Plant Sciences 2017年第10期8卷 2516-2529页

作者： Thais Aparecida Sales Maria Das Gracas Cardoso Luiz Gustavo de Lima Guimaraes Karen Caroline Camargo Danúbia Aparecida de Carvalho Selvati Rezende Rafaela Magalhães Brandao Rafaela Vieira souza Vanúzia Rodrigues Fernandes Ferreira Ana Ermelinda Marques Maísa Lamounier Magalhaes David Lee Nelson epartment of Chemistry Federal University of LavrasLavrasBrazil department of Natural Science Federal University of Sao Joao Del ReiSao Joao Del ReiBrazil department of Food Science Federal University of LavrasLavrasBrazil Pro-Reitoria de Pesquisa e Pós-Graduacao Federal University of the Jequitinhonha and Mucuri ValleysDiamantinaBrazil

The chemical compositions of the essential oils from the leaves and flowers of Callistemon viminalis and their insecticide and fungitoxic activities were determined. The essential oil was extracted by the hydrodistillation method using a modified Clevenger apparatus. The chemical characterization was performed by GC-MS and GC-FID. The evaluation of the insecticidal activity was performed with the Myzus persicae aphid, and the antifungal potential was determined via the inhibition of the mycelial growth of Alternaria alternata, Fusarium oxysorum and Botrytis cinérea phytopathogenic fungi. The principal components of the essential oils from the leaves and flowers were eucalyptol (84.60% and 61.47%), α-pinene (10.28% and 21.48%) and α-terpineol (2.59% and 2.79%), respectively. The use of a 0.5% concentration of the essential oil from the flowers influenced the preference of aphids and their reproduction. The number of adult aphids decreased within a period of 48 hours in the presence of the essential oil from the leaves. In the test with no chance of choice, the mean number of adults decreased with both oils within 48 hours. No inhibition of the mycelial growth of the A. alternate microorganism was observed in any of the treatments with the two essential oils. However, the growth of F. oxysporum and B. cinerea fungi was inhibited. The mycelial growth of F. oxysporum was inhibited with the concentration of 100 μL·Lˉ1 of the oil from the flowers and 250 μL·Lˉ1 of the oil from the leaves. The inhibition of the growth of B. cinerea was observed at concentrations of 500 and 100 μL·Lˉ1 for the oils from the flowers and leaves, respectively. The essential oils presented insecticidal and antifungal potentials. However, further studies are needed for these oils to be used in integrated pest management.

关键词： Myzus persicae Biological Activity Phytopathogenic Fungi Natural Products

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Motor speed estimation and failure detection of a small UAV using density of maxima

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Frontiers of Information Technology & Electronic Engineering 2021年第7期22卷 1002-1009页

作者： Jefferson S.souza Moises C.BEZERRIL Mateus A.SILVA Frank C.VERAS Abel LIMA-FILHO Jorge Gabriel RAMOS Alisson V.BRITO Laboratory of System Engineering and Robotics Federal University of ParaibaJoao PessoaBrazil department of Information Systems Federal University of PiauiPicosBrazil department of Mechanical Engineering Federal University of ParaibaJoao PessoaBrazil department of Physics Federal University of ParaibaJoao PessoaBrazil

This work presents the application of the technique named signal analysis based on chaos using density of maxima to analyze brushless direct current *** uses a correlation coefficient estimated from the density of maxima of the current *** study demonstrates in experiments the speed estimation of a brushless motor on a testbench and failure detection in a small flying *** experimental results demonstrate that it is possible to estimate the speed in 97.8%of the cases and to detect failure in 82.75%of the analyzed cases.

关键词： Unmanned aerial vehicle(UAV) Speed identification Failure detection Chaos

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DNA Vaccines Approach:From Concepts to Applications

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World Journal of Vaccines 2014年第2期4卷 50-71页

作者： Vanessa Bastos Pereira Meritxell Zurita-Turk Tessalia Diniz Luerce Saraiva Camila Prosperi de Castro Bianca Mendes souza Pamela Mancha Agresti Fernanda Alvarenga Lima Vanessa Nathalie Pfeiffer Marcela Santiago Pacheco Azevedo Clarissa Santos Rocha Daniela Santos Pontes Vasco Azevedo Anderson Miyoshi Laboratorio de Genetica Celular e Molecular Instituto de Ciencias BiologicasUniversidade Federal de Minas Gerais(UFMG)Belo HorizonteBrazil Universidade Estadual da Paraiba(UEPB) Joao PessoaBrazil

DNA vaccines are the third generation vaccines based on purified plasmid preparations containing transgenes that encode antigenic/therapeutic proteins or peptides capable of triggering an immune response against a wide range of diseases. This vaccine platform presents several attributes that confer distinct advantages over other vaccine technologies in terms of safety, ease of fabrication and stability. Many aspects, such as antigen expression and especially vector design, are under study because of their great influence on immunogenicity and efficacy of DNA vaccines. In this regard, with the attempt of improving the efficiency of DNA vaccines, co-expression of stimulatory sequences and diverse vector delivery systems are being optimized. With this in mind, this review aims to giving a conceptual approach of DNA vaccines, explaining their mechanisms of action and listing the already licensed veterinary DNA vaccines presented in the market.

关键词： DNA Vaccines Vector design delivery Systems Approved DNA Vaccines Bacterial delivery

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