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Uranium Metabolism Associated with Ontogenetic Growth of Birds—Case Studies with Broilers and Ducks

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Advances in Bioscience and Biotechnology 2014年第9期5卷 768-776页

作者： joao dias de toledo arruda-neto Guacyara Tenorio Cavalcante Guilherme de Paula Nogueira Tulio Eduardo Rodrigues Luiz Eduardo Correa Fonseca Mitiko Saiki Godofredo Camara Genofre Physics Institute University of Sao PauloSao PauloBrazil CEPESq/UniItalo—Italy-Brazilian University Center Sao PauloBrazil School of Veterinary Medicine Sao Paulo State University/UNESPAracatubaBrazil Institute for Energy and Nuclear Research IPEN/CNEN-SPSao PauloBrazil Institute for Biomedical Sciences University of Sao PauloSao PauloBrazil

Cobb broilers and domestic ducks, both one-day-old, were treated using ration doped with 20 ppm of uranyl nitrate. Uranium concentrations in the tibia (μg-U/g-bone) were measured by neutron activation analysis as function of the animals’ age, from the neonatal period to maturity. Results show that Uranium and Calcium qualitatively follow the same metabolic pathway, and that adult ducks incorporate on average ten times more Uranium than broilers. Data interpretation shows that the Uranium clearance rate in broilers is substantially higher than that in ducks, suggesting that metabolic characteristics favoring Calcium retention in bone may hinder the elimination of Uranium in ducks. The need for further comparative biochemistry studies between Galliformes and Anseriformes is addressed.

关键词： Cobb Broilers Domestic Ducks Uranium-Doped-Ration Uranium-Content in Bones U/Ca Metabolism Uranium Residence Times

Seasonal variation and host sex affect bat–bat fly interaction networks in the Amazonian savannahs

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Integrative Zoology 2024年第3期19卷 400-416页

作者： Paulo MEJIA Gustavo Lima URBIETA Bruna da Silva XAVIER IsaíJorge de CASTRO JoséJúlio de toledo Gustavo GRACIOLLI Lucio AndréVIANA dias William Douglas CARVALHO Programa de Pós-Graduação em Biodiversidade Tropical Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Programa de Pós-Graduação em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil Laboratório de Mamíferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Programa de Pós-Graduação em Biologia Animal Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestrial Ecology Group(TEG-UAM) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridMadridSpain

Bats are the second-most diverse group of mammals in the world,and bat flies are their main ***,significant knowledge gaps remain regarding these antagonistic interactions,especially since diverse factors such as seasonality and host sex can affect their network ***,we explore the influence of such factors by comparing species richness and composition of bat flies on host bats,as well as specialization and modularity of bat–bat fly interaction networks between seasons and adult host *** captured bats and collected their ectoparasitic flies at 10 sampling sites in the savannahs of AmapáState,northeastern region of the Brazilian *** female bats being more parasitized and recording greater bat fly species richness in the wet season,neither relationship was statistically *** pooled network could be divided into 15 compartments with 54 links,and all subnetworks comprised>12 *** total number of links ranged from 27 to 48(for the dry and wet seasons,respectively),and female and male subnetworks had 44 and 41 links,*** values were very low for the pooled network and for all *** results revealed higher bat fly species richness and abundance in the wet season,whereas specialization and modularity were higher in the dry ***,the subnetwork for female bats displayed higher specialization and modularity than the male ***,both seasonality and host sex contribute in different ways to bat–bat fly network *** studies should consider these factors when evaluating bat–bat fly interaction networks.

关键词： Amapá Amazon biome bat flies bats interaction networks

The Cauchy Problem for Coupled Nonlinear Schrdinger Equations with Linear Damping： Local and Global Existence and Blowup of Solutions

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Chinese Annals of Mathematics,Series B 2016年第5期37卷 665-682页

作者： joao-Paulo dias Mario FIGUEIRA Vladimir V. KONOTOP LCMAF-CIO Faculdade de Ciencias Universidade de Lisboa Av. Prof. Gama Pinto 2 1649-003 Lisboa Portugal. Centro de Fisica Teorica e Computacional and departamento de Fisica Faculdade de Ciencias Universidade de Lisboa Campo Grande Ed.C8 1749-016 Lisboa Portugal.

The authors study, by applying and extending the methods developed by Cazenave(2003), dias and Figueira(2014), dias et al.(2014), Glassey(1994–1997), Kato(1987), Ohta and Todorova(2009) and Tsutsumi(1984), the Cauchy problem for a damped coupled system of nonlinear Schrdinger equations and they obtain new results on the local and global existence of H^1-strong solutions and on their possible blowup in the supercritical case and in a special situation, in the critical or supercritical cases.

关键词： supercritical Cauchy applying estimates proof admissible constants uniqueness nonlinearity inequality

High-precision geochronology of Mesozoic magmatism in Macao,Southeast China:Evidence for multistage granite emplacement

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Geoscience Frontiers 2020年第1期11卷 243-263页

作者： Pedro Quelhas Agata Alveirinho dias joao Mata Donald Wayne Davis Maria Luísa Ribeiro Institute of Science and Environment University of Saint JosephMacaoChina Instituto Dom Luiz Faculdade de CiênciasUniversidade de LisboaLisboaPortugal Jack Satterly Geochronology Laboratory Department of Earth SciencesUniversity of TorontoTorontoOntCanada Laboratório Nacional de Engenharia e Geologia LisboaPortugal

Six new high precision U-Pb zircon ID-TIMS ages plus thirteen in situ high spatial resolution U-Pb zircon LA-MC-ICPMS ages are reported from Jurassic plutonic(metaluminous to weakly peraluminous biotite granites)and Jurassic to Cretaceous hypabyssal(dacites)rocks from *** its relatively small area(~30 km^2),the new ages tightly constrain the Macao granitic magmatism to two periods ranging from 164.5±0.6 Ma to 162.9±0.7 Ma and 156.6±0.2 Ma to 155.5±0.8 Ma,separated by ca.6 *** zircons point to the existence of a basement with ages up to Paleo-Proterozoic and late Archean in the *** addition,younger dacitic rocks were dated at 150.6±0.6 Ma andde *** two granitic magmatic pulses have distinct mineralogical and geochemical features that support their discrete nature rather than a continuum of comagmatic activity and suggest that the Macao granitic suite was incrementally assembled during a period of ca.9 Ma,a hypothesis also extendable to the neighboring Hong Kong region for a time lapse of ca.24 *** Macao,the transition from granitic magmatism(Middle to Upper Jurassic)to the younger dacite dykes(Upper Jurassic to Lower Cretaceous)most likely corresponds to a change in the regional tectonic setting,from an extensional regime related with foundering of the subducting paleoPacific plate during the Early Yanshanian period to the reestablishment of a normal subduction system in SE China during the Late Yanshanian period.

关键词： Granites U-Pb geochronology Zircon Jurassic Yanshanian orogeny Macao

The neuroprotective effect of traditional Chinese medicinal plants--A critical review

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Acta Pharmaceutica Sinica B 2023年第8期13卷 3208-3237页

作者： joao Moreira Mariana Machado Monica dias-Teixeira Ricardo Ferraz Cristina delerue-Matos Clara Grosso REQUIMTE/LAQV Instituto Superior de Engenharia do PortoInstituto Politecnico do PortoPorto 4249-015Portugal Ciencias Químicas e das Biomoleculas/CISA Escola Superior de SaudedInstituto Politecnico do PortoPorto 4200-072Portugal NICiTeS-Nucleo de Investigacao em Ciencias e Tecnologias da Saude Escola Superior de Saude Ribeiro SanchesLisboa 1950-396Portugal REQUIMTE/LAQV Departamento de Química e Bioquímica Faculdade de CienciasUniversidade do PortoPorto 4169-007Portugal

Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals’quality of life,thus increasing their cost to social and health *** diseases have overlapping mechanisms,such as oxidative stress,protein aggregation,neuroinflammation,neurotransmission impairment,mitochondrial dysfunction,and ***,there is no cure for neurodegenerative diseases,and the available therapies have adverse effects and low *** neuropsychiatric disorders,such as depression,the current therapies are not adequate to one-third of the patients,the so-called treatmentresistant ***,searching for new treatments is *** plants appear as a strong alternative and complement towards new treatment protocols,as they have been used for health purposes for thousands of ***,the main goal of this review is to revisit the neuroprotective potential of some of the most predominant medicinal plants(and one fungus)used in traditional Chinese medicine(TCM),focusing on their proven mechanisms of action and their chemical compositions,to give clues on how they can be useful against neurodegeneration progression.

关键词： Neurodegeneration Alzheimer's disease Parkinson's disease depression Medicinal plants Oxidative stress Toxicology Clinicaltrials

^(222)Rn calibration procedure for water analyses by liquid scintillation counting

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辐射探测技术与方法(英文) 2023年第2期7卷 311-319页

作者： Ana Rita Gomes Sérgio dias Anabela Mourato joao Abrantes Mário Reis Laboratório de Protecao e Seguranca Radiológica Instituto Superior TécnicoUniversidade de LisboaEstrada Nacional 10km 13972695‑066 Bobadela LRSPortugal Laboratórios de Massa e Massa Volúmica de Sólidos Instituto Portugues da QualidadeRua António Giao22829‑513 CaparicaPortugal Centro de Ciências e Tecnologias Nucleares Instituto Superior TécnicoUniversidade de LisboaEstrada Nacional 10km 13972695‑066 Bobadela LRSPortugal

Purpose Among the several methods to measure ^(222)Rn in water,the liquid scintillation counting(LSC)technique is one of the most sensitive and widely used when analysing non-saline waters by liquid extraction,providing excellent accuracy,precision and low-level detection *** using the liquid scintillation counter Tri-Carb 3170 TR/SL(Perkin-Elmer)it is not possible to make an automatic determination of the alpha/beta discrimination parameter,being necessary to evaluate the pulse decay discriminator(PDD)value manually to the ^(222)Rn *** this work,we describe the steps to perform the calibration of that type of *** The method consists in the preparation of standard samples from a ^(226)Ra certified standard solution and the adjustment of the PDD value by hand until the percentage of alpha events reaches a plateau of a near-constant fraction of total *** process consists in taking several measures between PDD 80 and 200 with 15 min counting time *** the plateau,the alpha/beta ratio was used to determine the plateau final range as well as the optimum PDD *** that,the calibration standards and blanks were measured and the region of interest(ROI)was established by finding the maximum value for the figure of merit(FOM)in the upper and lower *** The optimal PDD value of 148 was established by the alpha/beta ratio,and after that,it was possible to measure ^(226)Ra standards to perform the *** efficiency of(9.758±0.035)×1^(0-1) was *** routine measurements,a detection limit of about 0.50 Bq L^(-1) is achieved for a 120 min counting *** evaluate the uncertainty budget,the uncertainties of the net count rate,the efficiency,the sample amount and the decay correction factor were *** A method was developed for the calibration of LSC Tri-Carb 3170 TR/SL with the optimization of the PDD using a ^(226)Ra standard *** acquisition to obtain the plot of the variation

关键词： Radon Waters Pulse decay discriminator Liquid scintillation counting Calibration

Nutritional Quality and Effect on Disease Prevention of Vegetables

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Food and Nutrition Sciences 2019年第4期10卷 369-402页

作者： joao Silva dias University of Lisbon Instituto Superior de AgronomiaTapada da AjudaLisboaPortugal

Vegetables have remarkable nutritional and health benefits. There are good reasons to include vegetables in human diet since they are enriched in bioactive compounds and by this reason they may help reduce the risk of some diseases. In this paper it was analyzed the nutrition quality and effect on disease prevention of vegetables. Each vegetable family and each vegetable contain a unique combination of bioactive compounds. The health benefit of vegetables should not be linked to one type of vegetable. It is presented some experimental research evidences that vegetables exert anti-oxidative, anti-carcinogenic, anti-diabetic and cardiovascular disease lowering effects. The mechanism by which vegetable bioactive compounds decrease the risk of some of these diseases is complex and sometimes unknown.

关键词： Vegetables Health Benefits Healthier Life Nutrition ANDI Bioactive Compounds Antioxidants Dietary Fiber Vitamins Minerals Phytochemicals

Nutritional Quality and Health Benefits of Vegetables:A Review

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Food and Nutrition Sciences 2012年第10期3卷 1354-1374页

作者： joao Silva dias Technical University of Lisbon Instituto Superior de AgronomiaTapada da Ajuda1349-017 LisboaPortugal

Vegetables are considered essential for well-balanced diets since they supply vitamins, minerals, dietary fiber, and phytochemicals. Each vegetable group contains an unique combination and amount of these phytonutriceuticals, which distinguishes them from other groups and vegetables whithin their own group. In the daily diet vegetables have been strongly associated with improvement of gastrointestinal health, good vision, and reduced risk of heart disease, stroke, chronic diseases such as diabetes, and some forms of cancer. Some phytochemicals of vegetables are strong antioxidants and are thought to reduce the risk of chronic disease by protecting against free radical damage, by modifying metabolic activation and detoxification of carcinogens, or even by influencing processes that alter the course of tumor cells. All the vegetables may offer protection to humans against chronic diseases. Nutrition is both a quantity and a quality issue, and vegetables in all their many forms ensure an adequate intake of most vitamins and nutrients, dietary fibers, and phytochemicals which can bring a much-needed measure of balance back to diets contributing to solve many of these nutrition problems. The promotion of healthy vegetable products has coincided with a surging consumer interested in the healthy functionality of food. Because each vegetable contains a unique combination of phytonutriceuticals, a great diversity of vegetables should be eaten to ensure that individual’s diet includes a combination of phytonutriceuticals and to get all the health benefits. This article make a review and discusses the nutritional quality and health benefits of the major groups of vegetables. More interdisciplinary work is required that involves nutritional and food scientists as well as others from biomedical fields to ascertain the thrue function of specific phytonutriceuticals.

关键词： Antioxidants Dietary Fiber Horticulture Phytochemicals Phytonutriceuticals

Effect of a commercial dispersion of multi walled carbon nanotubes on the hydration of an oil well cementing paste

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Frontiers of Structural and Civil Engineering 2016年第2期10卷 174-179页

作者： Ocar Aurelio MENDOZA REALES William C. PEARL Jr Maria D. M. PAIVA Cristiane R. MIRANDA Romildo dias toledo FILHO Civil Engineering department PEC/COPPE Universidade Federal do Rio de Janeiro Rio de Janeiro 21941-972 Brazil Halliburton Brazil Technology Center Halliburton Rio de Janeiro 21941-907 Brazil CPetrobras Petroleo Brasileiro S.A Rio de Janeiro 21941-901 Brazil

This work studies the influence of a commercial dispersion of multi wall carbon nanotubes （MWCNT） on the hydration of a class G cement paste, at room and elevated down-hole temperatures. The MWCNT dispersion was produced with a solids concentration of 3.0 % by mass and an anionic surfactant as dispersing agent. Cement pastes with water-to-cement ratio of 0.45 and additions of solid MWCNT by mass of cement up to 0.50 % were studied. Isothermal calorimetry results showed a clear retardation of the hydration of cement caused by the surfactant contained in the MWCNT dispersion. Nevertheless, thermogravimetric evaluations showed that once the hydration reaction resumed, the retardation effect of the surfactant did not have a negative impact on the amount of hydration products precipitated. It was concluded that the commercial MWCNT dispersion presents a good potential to be applied in oil well cement pastes.

关键词： carbon nanotubes surfactant retardation combined water C-S-H