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动力传动圆锥渐开线齿轮的设计、制造和应用

传动技术 2007年第4期21卷 3-14,45页

作者： J.brner K.Humm F.joachim H.Yakaria ZF Friedrichshafen AG 88038 FriedrichshafenGermany Dr. ZF Friedrichshafen AG 88038 FriedrichshafenGermany

关键词：表面镀层精加工过程齿轮试验变速器

Reduced bone mineral density and altered bone turnover markers in patients with non-cirrhotic chronic hepatitis b or C infection

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World Journal of Gastroenterology 2005年第12期11卷 1843-1847页

作者： Ingolf Schiefke Andreas Fach Marcus Wiedmann Andreas V.Aretin Eva Schenker Gudrun borte Manfred Wiese joachim Moessner Department Department of Radiology Department of Internal Medicine Ⅱ

AIM: Previous studies suggest that loss of bone mineral density (bMD) frequently occurs in patients with chronic viral liver disease, presenting with histologically proven liver cirrhosis. However, little is known about the occurrence of bone disease in non-cirrhotic patients with chronic hepatitis b or C. Therefore, it was the aim of this study to evaluate this particular population for bMD and bone turnover markers. METHODS: biochemical markers of bone turnover and bMD were measured in 43 consecutive patients with HCV (n = 30) or HbV (n = 13) infection without histological evidence for liver cirrhosis. Mean age was 49 years (range 26-77 years). bMD was measured by dual X-ray absorptiometry in the femoral neck (FN) and the lumbar spine (LS) region. In addition, bone metabolism markers were measured. RESULTS: bMD was lowered in 25 (58%) of the patients with chronic hepatitis b or C (FN; 0.76 (0.53-0.99); LS: 0.96 (0.62-1.23) g/cm2). Eight (32%) osteopenic patients were diagnosed with osteoporosis. bone-specific alkaline phosphatase (P= 0.005) and intact parathyroid hormone (iPTH) (P = 0.001) were significantly elevated in the more advanced stages of fibrosis. Mean T-score value was lower in patients with chronic hepatitis C as compared to patients suffering from chronic hepatitis b; however, the difference was not statistically significant (P= 0.09). CONCLUSION: There was a significantly reduced bMD in non-cirrhotic patients with chronic hepatitis b or C infection. Alterations of bone metabolism already occurred in advanced liver fibrosis without cirrhosis. According to our results, these secondary effects of chronic viral hepatitis should be further investigated.

关键词： bone density Chronic viral hepatitis Non cirrhotic patients

降低变速器、车桥和转向系统的功率损失(二)

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传动技术 2013年第1期27卷 10-15页

作者： F.-J.joachim J.brner N.Kurz ZF Friedrichshafen AG

车辆传动系统的最佳设计能够有效降低CO2的排放。手动变速器、液力机械变速器、DCT、CVT和混合动力系统等不同的传动系统适用于不同的需求和不同的车辆。通过增加档位和速比范围,发动机可在不降低车辆动力性的前提下燃油经济性更佳。变... 详细信息

车辆传动系统的最佳设计能够有效降低CO2的排放。手动变速器、液力机械变速器、DCT、CVT和混合动力系统等不同的传动系统适用于不同的需求和不同的车辆。通过增加档位和速比范围,发动机可在不降低车辆动力性的前提下燃油经济性更佳。变速器自身的效率可通过采用燃油效率更高的变速器润滑油、改善润滑系统及油泵、优化换档策略和优化齿轮、轴承及密封等得以提高。随着采用能够承受更高负载的轻量化材料和部件,变速器的转矩/质量比大幅提升。在上述领域,未来进一步的改进将集中在新型润滑、材料、部件、制造工艺、成本和用户效益等方面。

关键词：动力损失传动系统燃油消耗 CO2排放

Nonclassical Radiation from Two Atoms and Quantum Search Algorithms

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Nonclassical Radiation from Two Atoms and Quantum Search Alg...

Schaftoside inhibits 3CL^(pro)and PL^(pro)of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19

第十二届全国量子光学学术会议

作者： G．S．Agarwal joachim von Zanthier T．bastin Department of Physics Oklahoma State University StillwaterOK 74078-3072USA Institute of Optics Information and Photonics University Erlangen-NurembergD-91058 ErlangenGermany Institut de Physique Nucléaire Atomique et de Spectroscopie Universitéde Liége au Sart TilmanB-4000 LiégeBelgium

＜正＞We discuss the non-classical aspects of the radiation emitted from a system of two atoms. We first consider the radiation emitted from independently radiating quantum systems. If the atoms are excited by coherent light then the radiation exhibits the usual interference fringes in the far field as the point of observation is varied . by contrast,

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Acta Pharmaceutica Sinica b 2022年第11期12卷 4154-4164页

作者： Yang Yi Meng Zhang Heng Xue Rong Yu Yang-Oujie bao Yi Kuang Yue Chai Wen Ma Jing Wang Xiaomeng Shi Wenzhe Li Wei Hong Junhua Li Elishiba Muturi Hongping Wei joachim Wlodarz Szczepan Roszak Xue Qiao Hang Yang Min Ye State Key Laboratory of Natural and biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China CAS Key Laboratory of Special Pathogens and biosafety Center for Biosafety Mega-ScienceWuhan Institute of VirologyChinese Academy of SciencesWuhan 430071China University of Chinese Academy of Sciences Bejing 100049China Faculty of Science and Technology University of SilesiaKatowice 40-007Poland Department of Phrysical and Quantum Chenmistry Faculty of ChemistryWroclaw University of Science and Technology Wroclaw 50-370Poland

It is an urgent demand worldwide to control the coronavirus disease 2019(COVID-19)pandemic caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** 3-chymotrypsin-like protease(3CL^(pro))and papain-like protease(PL^(pro))are key targets to discover SARS-CoV-2 *** screening 12 Chinese herbal medicines and 125 compounds from licorice,we found that a popular natural product schaftoside inhibited 3CL^(pro)and PL^(pro)with IC_(50)values of 1.73±0.22 and 3.91±0.19μmol/L,respectively,and inhibited SARS CoV-2 virus in Vero E6 cells with EC_(50)of 11.83±3. 23μmol/L. Hydrogen-deuterium exchange mass spectrometry analysis, quantum mechanics/molecular mechanics calculations, together with site-directed mutagenesis indicated the antiviral activities of schaftoside were related with non-covalent interactions with H41, G143 and R188 of3CLpro, and K157, E167 and A246 of PLpro. Moreover, proteomics analysis and cytokine assay revealed that schaftoside also regulated immune response and inflammation of the host cells. The antiinflammatory activities of schaftoside were confirmed on lipopolysaccharide-induced acute lung injury mice. Schaftoside showed good safety and pharmacokinetic property, and could be a promising drug candidate for the prevention and treatment of COVID-19.

关键词： COVID-19 SARS-CoV-2 3-Chymotrypsin-like protease Papain-like protease Licorice Schaftoside Immune response Infammation

Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.bai O.bakina I.balossino Y.ban H.-R.bao V.batozskaya K.begzsuren N.berger M.berlowski M.bertani D.bettoni F.bianchi E.bianco A.bortone I.boyko R.A.briere A.brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.b.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori b.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng K.Fischer M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck b.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.b.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou b.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.b.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.b.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.b.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang M.Kavatsyuk b.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.b.Kolcu b.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.Lane P.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff M.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.Li H.b.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li M.H.Li P.R.Li Q.M.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China beihang University Beijing 100191China bochum Ruhr-University D-44780 BochumGermany budker Institute of Nuclear Physics Sb RAS(bINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the bESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the b^(−)→DK^(−)decay.

关键词： bESIII D^(0)meson decays amplitude analysis CP-even fraction

Associations between diagnosis with stroke,comorbidities,and activity of daily living among older adults in the United States

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Chronic Diseases and Translational Medicine 2023年第2期9卷 164-176页

作者： Suebsarn Ruksakulpiwat Wendie Zhou Lalipat Phianhasin Chitchanok benjasirisan Saeideh Salehizadeh Limin Wang joachim G.Voss Department of Medical Nursing Faculty of NursingMahidol UniversityBangkokThailand School of Nursing Peking UniversityBeijingChina University Hospitals Cleveland Medical Center ClevelandOhioUSA School of Nursing Zhejiang Chinese Medical UniversityZhejiangChina Frances Payne bolton School of Nursing Case Western Reserve UniversityClevelandOhioUSA

background:Stroke is the leading cause of *** study aimed to investigate the association between stroke,comorbidities,and activity of daily living(ADL)among older adults in the United ***:Participants were 1165 older adults aged 60 and older from two waves(2016 and 2018)of the Health and Retirement Study who had a *** statistics were used to describe demographic information and *** regressions and multiple regression analyses were used to determine associations between stroke,comorbidities,and ***:The mean age was 75.32±9.5 years,and 55.6%were *** adjusted analysis shows that older stroke adults living with diabetes as comorbidity are significantly associated with difficulty in dressing,walking,bedding,and ***,depression was significantly associated with difficulty in dressing,walking,bathing,eating,and *** the same time,heart conditions and hypertension as comorbidity were rarely associated with difficulty in *** adjusting for age and sex,heart condition and depression are significantly associated with seeing a doctor for stroke(odds ratio[OR]:0.66;95%confidence interval[CI]:0.49-0.91;p=0.01)and stroke therapy(OR:0.46;95%CI:0.25-0.84;p=0.01).Finally,stroke problem(unstandardizedβ[b]=0.58,p=0.017)and stroke therapy(b=1.42,pbenefit healthcare professionals in developing further interventions to improve older stroke adults'lives,especially those with a high level of dependence.

关键词： activity of daily living comorbidity older adults stroke

枯草芽孢杆菌b2菌株产生的抑菌活性物质分析

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中国生物防治 2003年第4期19卷 175-179页

作者：高学文姚仕义 Huong Pham joachim Vater 王金生南京农业大学农业部病虫监测与治理重点开放实验室南京210095 柏林理工大学生物化学和分子生物学研究所

枯草芽孢杆菌b2菌株产生的胞外物质经盐酸沉淀,甲醇抽提获得粗制备物。利用HPLC系统将粗制备物过XterraRP18层析柱分离,共获得120管收集液。以抑制小麦赤霉病菌分生孢子萌发为指标对各管收集液的抑菌活性进行了测定。通过LC MS分析,结... 详细信息

枯草芽孢杆菌b2菌株产生的胞外物质经盐酸沉淀,甲醇抽提获得粗制备物。利用HPLC系统将粗制备物过XterraRP18层析柱分离,共获得120管收集液。以抑制小麦赤霉病菌分生孢子萌发为指标对各管收集液的抑菌活性进行了测定。通过LC MS分析,结果表明b2菌株胞外存在3种抑菌物质,即脂肽类抗生素表面活性素、多烯类和一种分子量为564的结构未知的新物质。

关键词：枯草芽孢杆菌分离纯化抑制活性植物病害防治抑菌活性物质

Physical and Technological Parameters of Maize Varieties (Zea mays L.) Grown in the Southern Parts of benin and the Influence of Chemical Composition

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Food and Nutrition Sciences 2016年第14期7卷 1386-1400页

作者： Josiane Adjobignon Semassa Victor bienvenu Anihouvi Adolphe Adjanohoun Wilfrid Padonou joachim Gbénou Lamine baba-Moussa Laboratoire des Sciences des Aliments Faculté des Sciences Agronomiques Université d’Abomey-Calavi Cotonou Bénin Laboratoire de biologie et de Typage Moléculaire en Microbiologie Département de Biochimie et de Biologie Cellulaire Université d’Abomey-Calavi Cotonou Bénin Centre de Recherches Agricoles Sud Institut National des Recherches Agricoles du Bénin Attogon Bénin Programme Technologie Agricole et Alimentaire Centre de Recherches Agricoles d’Agonkanmey Institut National des Recherches Agricoles du Bénin Abomey-Calavi Bénin Laboratoire de Pharmacognosie et des huiles essentielles Faculté des Sciences et Techniques Université d’Abomey-Calavi Cotonou Bénin

Objective: The study aims to investigate some physical and technological parameters of varieties of maize collected from the most representative areas of maize production in the southern part of benin, and mainly used by the populations of those areas. Method: The chemical composition, physical and technological characteristics of the grains were determined using standard methods. Results: The results showed that the weight of 1000 grains ranges from 158.01 to 305.12 g, the length from 0.79 to 1.81 cm, the average width from 0.74 to 1.51 cm, thickness from 0.36 to 0.85 cm and density from 1.07 to 1.25. Regarding the technological parameters, the hardness of the grains before and after cooking was between 16.78 and 47.20 kgf, and 0.23 and 0.71 kgf respectively, while the cooking time varies from 71.00 and 158.33 mn. There was a positive and significant correlation (r = 0.405;p between the hardness after cooking and the weight of 1000 grains, between the hardness after cooking and grain width (r = 0.460;p bserved between the hardness after cooking and the grain length, between the hardness after cooking and the thickness of grain (r = 0.476, p between the grain density and the weight of 1000 grains (r = 0.481, p bserved between maize grain length and width, and between grain length and grain thickness (r = 0.764, p between the width and thickness (r = 0.764, p between the hardness before cooking and the thickness and between the hardness before cooking and sphericity index (r = -0465*, p Conclusion: Through its chemical and technological characteristics the maize constitutes an important raw material for many culinary recipes in West African region.

关键词： Maize Physical Characteristics Technological Parameters Chemical Parameters