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Large Scale Mass Movements Triggered by the Kashmir Earthquake 2005,Pakistan

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Journal of Mountain Science 2014年第1期11卷 19-30页

作者： Muhammad BASHARAT joachim ROHN Mirza Shahid BAIG Muhammad Rustam KHAN Markus SCHLEIER GeoZentrum Nordbayern Friedrich-Alexander-University Erlangen-Nuremberg Institute of Geology University of Azad Jammu and Kashmir

The SPOT image analysis in Muzaffarabad Azad Kashmir,northwest Himalayas,Pakistan reveals that the Kashmir earthquake 2005 triggered a number of coseismic mass movements along the hanging wall block of the Muzaffarabad *** Neelidandi and Langarpura rock falls have been identified as two major reactivated mass movements with an estimated volume of 3.1 × 106m3and 5.76 × 106m3,*** Neelidandi and Langarpura mass movements were initiated during earthquake in the direction of northwest-southeast extension and northeastsouthwest directed thrusting,*** Neelidandi rock fall occurred in sheared cherty dolomites and limestones of the Cambrian Muzaffarabad Formation,whereas the Langarpura rock fall occurred in alternating clays,shales,claystones,siltstones and sandstones of the Miocene Murree *** rock units along the fault are highly fractured and *** geotechnical maps and geological longitudinal profiles show the relationship between the geometrical characteristics and mechanism of these mass *** characteristics were analyzed according to the role of topographic,seismic,geological and tectonic *** steep topography,sheared rocks,lithology,coseismic uplift and strong ground shaking of the hanging wall block along Muzaffarabad Fault facilitated the gravity collapse of these mass movements.

关键词： Coseismic mass movements Himalayas Muzaffarabad Fault Geological and tectonic factors Earthquake Rock fall

Optimal physicochemical properties of dried litchis for Thai consumers

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International Journal of Agricultural and Biological Engineering 2014年第5期7卷 103-110页

作者： Marcelo Precoppe Marcus Nagle Busarakorn Mahayothee Patchimaporn Udomkun Serm Janjai joachim Muller Institute of Agricultural Engineering in the Tropics and Subtropics(440e) Universitat HohenheimGarbenstr.9D-70593StuttgartGermany Department of Food Technology Silpakorn University73000 Nakhon PathomThailand Department of Physics Silpakorn University73000 Nakhon PathomThailand

The litchi is a fruit essential for the economies of several Southeast Asian countries,but markets regularly reject it,mainly due to *** extends the shelf-life of litchis,but in Thailand the optimal characteristics of the dried product have not yet been *** purpose of this study was to determine the optimum physicochemical properties of dried litchis-those suitable for Thai *** dried fruits were submitted to physicochemical measurement and consumer evaluation,with datasets subsequently integrated using circular ideal-point regression *** surface methodology was then used to predict the optimum physicochemical properties of the *** was found that Thai consumer preferences with regard to dried litchis are for the fruits to be of golden-yellow color(L*ranging around 54;H ranging around 79°),to have a soft flesh(SMF ranging between 13 and 14 kN/100 g)and to have a sweet taste(TSS:TA ranging between 25 and 28).The results may be used in the future to prescribe pretreatments and drying conditions.

关键词： consumer preference response surface methodology circular ideal-point regression product optimization market acceptance lychee

Long-term results of endoscopic balloon dilatation of lower gastrointestinal tract strictures in Crohn's disease:A prospective study

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World Journal of Gastroenterology 2009年第21期15卷 2623-2627页

作者： Klaus Stienecker Daniel Gleichmann Ulrike Neumayer H joachim Glaser Carolin Tonus Department of Gastroenterology Herz-Jesu-Hospital Fulda Department of Visceral Surgery Herz-Jesu-Hospital Fulda

AIM:To examine the long-term results of endoscopic treatment in a prospective study conducted over a period of 10 years,1997 to January ***:A total of 25 patients(20 female and five male:aged 18-75 years),with at least one symptom of stricture not passable with the standard colonoscope and with a confirmed scarred Crohn's stricture of the lower gastrointestinal tract,were included in the *** main symptom was abdominal *** endoscopic balloon dilatation was performed with an 18 mm balloon under endoscopic and radiological ***:Eleven strictures were located in the colon,13 at the anastomosis after ileocecal resection,three at the Bauhin valve and four in the *** patients had two strictures and one patient had three *** the 31 strictures,in 30 was balloon dilatation successful in a single endoscopic session,so that eventually the strictures could be passed easily with the standard *** one patient with a long stricture of the ileum involving the Bauhin valve and an additional stricture of the ileum which were 15 cm apart,sufficient dilatation was not *** patient therefore required *** of abdominal symptoms was achieved in all cases which had technically successful balloon dilatation,althoughin one case perforation occurred after dilatation of a recurrent *** follow-up was in the range of 54-118 mo(mean of 81 mo).The relapse rate over this period was 46%,but 64% of relapsing strictures could be successfully dilated *** in four patients was surgery required during this follow-up ***:We conclude from these initial results that endoscopic balloon dilatation,especially for short strictures in Crohn's disease,can be performed with reliable *** is a rare *** is our opinion that in the long-term,the relapse rate is probably higher than after surgery,but usually a second endoscopic treatment can be performed successfully,leading to

关键词：腹痛消化道治疗方法结肠镜

Stress-activated kinases as therapeutic targets in pancreatic cancer

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World Journal of Gastroenterology 2021年第30期27卷 4963-4984页

作者： Benno Traub Aileen Roth Marko Kornmann Uwe Knippschild joachim Bischof Department of General and Visceral Surgery Ulm University HospitalUlm 89081Germany

Pancreatic cancer is a dismal disease with high incidence and poor survival *** the aim to improve overall survival of pancreatic cancer patients,new therapeutic approaches are urgently *** kinases are key regulatory players in basically all stages of development,maintaining physiologic functions but also being involved in pathogenic processes.c-Jun N-terminal kinases(JNK)and p38 kinases,representatives of the mitogen-activated protein kinases,as well as the casein kinase 1(CK1)family of protein kinases are important mediators of adequate response to cellular stress following inflammatory and metabolic stressors,DNA damage,and *** their physiologic roles,they are responsible for the regulation of cell cycle progression,cell proliferation and differentiation,and *** of the underlying pathways consequently has been identified in various cancer types,including pancreatic *** targeting of those pathways has been the field of interest for several *** success in earlier studies was limited due to lacking specificity and off-target effects,more recent improvements in small molecule inhibitor design against stress-activated protein kinases and their use in combination therapies have shown promising in vitro ***,targeting of JNK,p38,and CK1 protein kinase family members may actually be of particular interest in the field of precision medicine in patients with highly deregulated kinase pathways related to these ***,further studies are warranted,especially involving in vivo investigation and clinical trials,in order to advance inhibition of stress-activated kinases to the field of translational medicine.

关键词： Pancreatic cancer Stress-activated protein kinases Mitogen-activated protein kinases c-Jun N-terminal kinases Casein kinase 1 Small molecule inhibitor

基于等效黏弹性模型获取土体最大动剪模量的计算方法

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岩石力学与工程学报 2013年第S2期32卷 4082-4090页

作者：项伟江洎洧 joachim Rohn 中国地质大学教育部长江三峡库区地质灾害研究中心湖北武汉430074 长江科学院水利部岩土力学与工程重点实验室湖北武汉430010 爱尔兰根纽伦堡大学应用地质系

土动力特性参数中,最大动剪切模量Gmax是定量描述土动力学本构最重要的参量之一,现有研究方法通常需较多参量及工程经验方能对其进行半定量的计算,但天然状态条件下土体的Gmax真值是唯一且确定的。为此,结合对土体动力学特性广泛适用性... 详细信息

土动力特性参数中,最大动剪切模量Gmax是定量描述土动力学本构最重要的参量之一,现有研究方法通常需较多参量及工程经验方能对其进行半定量的计算,但天然状态条件下土体的Gmax真值是唯一且确定的。为此,结合对土体动力学特性广泛适用性的基于等效黏弹性理论的修正Davidenkov模型,基于土动三轴试验,提出对该模型中的3个参量多元回归和对Gmax自适应逼近迭代的反分析算法,用于求取Gmax并得到本构方程中所需系数。研究表明:该算法在同时满足Davidenkov模型曲线三参数对测试数据拟合以及反算Gmax残差最小的双重计算约束条件下,对3类土样的动三轴测试数据进行拟合,在规避直接获取Gmax存在困难的情况下,顺利得到各测试样本的动本构模型。

关键词：土力学修正Davidenkov模型最大动剪模量Gmax 自适应逼近算法动力三轴测试

克立格估计的分析解释与协方差函数的代数确定

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地球科学（中国地质大学学报） 2000年第2期25卷 195-200页

作者：边少锋 joachim Menz 中国科学院测量与地球物理研究所武汉430077 TU Bergakade mie Freiberg

首先引入利用旋转面作为基函数的函数逼近概念 ,在此基础上经过复杂的矩阵推导证明泛克立格法可表示为传统的带权最小二乘多项式拟合与以旋转面作为基函数的函数逼近 ,并在一定条件下 (随机场高度连续无块金效应 )论证了协方差 (即旋转... 详细信息

首先引入利用旋转面作为基函数的函数逼近概念 ,在此基础上经过复杂的矩阵推导证明泛克立格法可表示为传统的带权最小二乘多项式拟合与以旋转面作为基函数的函数逼近 ,并在一定条件下 (随机场高度连续无块金效应 )论证了协方差 (即旋转面 )的参数可通过数学分析的方法确定 ,给出了以高斯函数为例确定协方差函数的两个准则 .

关键词：克立格估计协方差函数地质统计学代数确定

Theory of superfluidity and drag force in the one-dimensional Bose gas

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Frontiers of physics 2012年第1期7卷 54-71页

作者： Alexander Yu. Cherny (1) Jean-Sébastien Caux (2) joachim Brand (3) 1. Bogoliubov Laboratory of Theoretical Physics Joint Institute for Nuclear Research 141980 Dubna Moscow region Russia2. Institute for Theoretical Physics Science Park 904 University of Amsterdam 1090 GL Amsterdam The Netherlands3. Centre for Theoretical Chemistry and Physics and New Zealand Institute for Advanced Study Massey University Private Bag 102904 North Shore Auckland 0745 New Zealand

The one-dimensional Bose gas is an unusual superfluid. In contrast to higher spatial dimensions, the existence of non-classical rotational inertia is not directly linked to the dissipationless motion of infinitesimal impurities. Recently, experimental tests with ultracold atoms have begun and quanti- tative predictions for the drag force experienced by moving obstacles have become available. This topical review discusses the drag force obtained from linear response theory in relation to Lan- dau＇s criterion of superfluidity. Based upon improved analytical and numerical understanding of the dynamical structure factor, results for different obstacle potentials are obtained, including single impurities, optical lattices and random potentials generated from speckle patterns. The dynamical breakdown of superfluidity in random potentials is discussed in relation to Anderson localization and the predicted superfluid-insulator transition in these systems.

关键词： Lieb-Liniger model Tonks-Girardeau gas Luttinger liquid drag force superfluidity,dynamical structure factor

Formation of crystalline particles from phase change emulsion： Influence of different parameters

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Chinese Journal of Chemical Engineering 2016年第7期24卷 929-936页

作者： Javed Iqbal Zulfiqar Ali Murid Hussain Rizwan Sheikh Khaliq Majeed Asad Ullah Khan joachim Ulrich COMSATS Institute of Information Technology Department of Chemical Engineering Defence Road Off Raiwind Road Lahore Pakistan Martin-Luther-Universitat Halle-Wittenberg Zentrum fur Ingenieurwissenschaften Verfahrenstechnik/TVT D-06099 Halle (Saale) Germany

Solidification or crystallization of phase change emulsion in the form of fine emulsion drops in a direct contact coolant at temperatures below their freezing point was studied. This work is mainly focused on the size and shape of the generated particles from phase change emulsified fats. Size of the particles is the major or key factor being considered during their formation, however, other factors that govern the particle size and shape were also observed. The operating parameters of the process were optimized in order to obtain particles of smaller size ranges in the window of current operating conditions. The crystallization of complex emulsion matrices is very difficult to control in the bulk at desired requirement. Hence, the emulsion drop to particle formation has advantage in comparison with the bulk solidification or crystallization. The main objective of this work is to achieve spherical emulsion particles in a direct contact cooling system. Parameters like: stability, characterization, viscosity, and the effect of different energy inputs were examined. Moreover, the effects of the capillary size, interfacial tension, temperature of the emulsion on the particle size were also monitored.

关键词：结晶颗粒复合乳液物相变化直接接触颗粒大小操作参数操作条件冷却系统

Calcium-Dependent Protein Kinase CPK21 Functions in Abiotic Stress Response in Arabidopsis thaliana

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Molecular Plant 2011年第1期4卷 83-96页

作者： Sandra Franz Britta Ehlert Anja Liese joachim Kurth Anne-Claire Cazale Tina Romeis Department of Plant Biochemistry Institute for Biology Freie Universitat Berlin Koenigin-Luise-Str. 12-16 14195 Berlin Germany Department of Plant Microbe Interactions Max-Planck-lnstil:ute for Plant Breeding Research Carl-von-Linne-Weg 10 50935 Cologne Germany Present address: Laboratoire des Interactions Plantes Micro-organismes (LIPM) UMR CNRS-INRA 25941441 31320 Castanet-Tolosan France

Calcium-dependent protein kinases （CDPKs） comprise a family of plant serine/threonine protein kinases in which the calcium sensing domain and the kinase effector domain are combined within one molecule. So far, a biological function in abiotic stress signaling has only been reported for few CDPK isoforms, whereas the underlying biochemical mechanism for these CDPKs is still mainly unknown. Here, we show that CPK21 from Arabidopsis thaliana is biochemically activated in vivo in response to hyperosmotic stress. Loss-of-function seedlings of cpk21 are more tolerant to hyperosmotic stress and mutant plants show increased stress responses with respect to marker gene expression and metabolite accumulation. In transgenic Arabidopsis complementation lines in the cpk21 mutant background, in which either CPK21 wildtype, or a full-length enzyme variant carrying an amino-acid substitution were stably expressed, stress responsitivity was restored by CPK21 but not with the kinase inactive variant. The biochemical characterization of in planta synthesized and purified CPK21 protein revealed that within the calcium-binding domain, N-terminal EF1- and EF2-motifs compared to C-terminal EF3- and EF4-motifs differ in their contribution to calcium-regulated kinase activity, suggesting a crucial role for the N-terminal EF-hand pair. Our data provide evidence for CPK21 contributing in abiotic stress signaling and suggest that the N-terminal EF-hand pair is a calcium-sensing determinant controlling specificity of CPK21 function.

关键词： Abiotic/environmental stress calcium signaling/transport Arabidopsis CDPK EF-hand.