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Successful treatment of basaloid squamous cell carcinoma in the rectosigmoid colon: A case report and review of literature

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World journal of Clinical Cases 2020年第14期8卷 3057-3063页

作者： Taek-Gu lee Soon Man Yoon Myung jo Kim Department of Surgery Chungbuk National University HospitalChungbuk National University College of MedicineCheongju 28644South Korea Department of Internal Medicine Chungbuk National University HospitalChungbuk National University College of MedicineCheongju 28644South Korea

BACKGROUND Compared with colorectal adenocarcinoma,basaloid squamous cell carcinomas(BSCCs)arising in the colorectum are rare and have very poor *** date,only nine cases have been *** BSCCs are extensively involved in metastasis to the lymph node,liver,and lung at *** many clinicians attempting to effectively treat BSCCs,therapeutic consensus has not been established due to lack of *** SUMMARY A 58-year-old woman presented with abdominal pain,diarrhea,fever,and *** was referred from a department of gynecology and was diagnosed with a suspicious leiomyosarcoma of the rectum or a pedunculated myoma of the *** exophytic growing mass at the right lateral wall of the rectum with an internal cystic portion and hemorrhage was observed on magnetic resonance *** patient underwent low anterior resection and total hysterectomy with bilateral *** findings revealed a cellular mass with a solid growth pattern and few glandular structures,many foci of intratumoral necrosis,and a palisading *** pathologist diagnosed tumor as a BSCC,and the patient received chemotherapy with fluorouracil/leucovorin without *** patient is currently alive 8 years after the surgery with no manifestations of metastatic colon *** Our case suggest that curative resection and chemotherapy play important roles in improving survival,and radiotherapy may be an option to avoid radiationassociated enteritis.

关键词： Basaloid squamous cell carcinomas Rectosigmoid colon Colorectal cancer Adjuvant chemotherapy Curative resection Case report

Modelling charge transport and electro-optical characteristics of quantum dot light-emitting diodes

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npj Computational Materials 2021年第1期7卷 1116-1126页

作者： Sung-Min Jung Tae Hoon lee Sang Yun Bang Soo Deok han Dong-Wook Shin Sanghyo lee Hyung Woo Choi Yo-han Suh Xiang-Bing Fan Jeong-Wan jo Shijie Zhan Jiajie Yang Chatura Samarakoon Yoonwoo Kim Luigi GOcchipinti Gehan Amaratunga jong Min Kim Electrical Engineering Division Department of EngineeringUniversity of CambridgeCambridgeUnited Kingdom

Quantum dot light-emitting diodes(QD-LEDs)are considered as competitive candidate for next-generation displays or *** advances in the synthesis of core/shell quantum dots(QDs)and tailoring procedures for achieving their high quantum yield have facilitated the emergence of high-performance ***,the charge-carrier dynamics in QD-LED devices,which constitutes the remaining core research area for further improvement of QD-LEDs,is,however,poorly understood ***,we propose a charge transport model in which the charge-carrier dynamics in QD-LEDs are comprehensively described by computer *** charge-carrier injection is modelled by the carrier-capturing process,while the effect of electric fields at their interfaces is *** simulated electro-optical characteristics of QD-LEDs,such as the luminance,current density and external quantum efficiency(EQE)curves with varying voltages,show excellent agreement with ***,our computational method proposed here provides a useful means for designing and optimising high-performance QD-LED devices.

关键词： quantum charge competitive

Integrated management of facility,process,and output:data model perspective

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Science China(Information Sciences) 2012年第5期55卷 994-1007页

作者： lee Seunghoon han Soonhung MUN Duhwan Department of Mechanical Engineering Korea Advanced Institute of Science and Technology373-1 Gusong-dongYuseong-guDaejeon 305-701South Korea Division of Ocean Systems Engineering Korea Advanced Institute of Science and TechnologyDaejeon 305-701South Korea Department of Precision Mechanical Engineering Kyungpook National University386 Gajang-dongSangjuGyeongsangbuk-do 742-711South Korea

As the manufacturing industry matures,vast amounts of data related to products are created by many kinds of engineering systems during the manufacturing *** include data for a variety of facilities,manufacturing processes,and the input and output of each process (input material,by-products,and intermediate and final products).Effective operation and maintenance of manufacturing facilities and eco-friendly products are gradually becoming important issues due to increased environmental regulations and changes in the enterprise business *** this reason,increased efficiency in data management is necessary in the manufacturing *** this paper,existing data models for the integration of lifecycle data are analyzed according to their application *** the analysis,information requirements for the integrated management of facility,process,and output data are *** to these requirements,a data model appropriate for this integration is *** an application case study,the use of the proposed data model for the effective operation and maintenance of manufacturing facilities is ***,benefit,limitation,and improvement of the proposed data model are discussed.

关键词： integrated product data management ISO 10303 STEP PDM schema ISO 10303 STEP PLCS ISO 15926 process plants product lifecycle management manufacturing facility management

Intermetallic Evolution of Al–Si-Coated Hot Stamping Steel During Modified Electrically Assisted Rapid Heating

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Acta Metallurgica Sinica(English Letters) 2018年第12期31卷 1327-1333页

作者： Kieu-Anh Dinh Sung-Tae Hong Tien Viet Luu Moon-jo Kim Heung Nam han School of Mechanical Engineering University of Ulsan Liquid Processing & Casting R&D Group Korea Institute of Industrial Technology Department of Materials Science and Engineering RIAMSeoul National University

Modified electrically assisted(EA) rapid heating of Al–Si-coated hot stamping steel is suggested, and the intermetallic evolution in the coating during heating is experimentally investigated. In the modified EA rapid heating, a continuous electric current for a suitable duration is applied to a specimen to heat it to a temperature slightly below the melting temperature of the coating. The temperature of the specimen is then kept constant for a specified dwell time. The result of the microstructural analysis shows that the modified EA rapid heating could effectively increase the thickness of the intermetallic layer between the coating and steel substrate much faster than conventional furnace heating and induction heating. The effectiveness of EA rapid heating may be due to the athermal effect of the electric current on the mobility of atoms, in addition to the well-known resistance heating effect. EA rapid heating also provides a technical advantage in that partial austenization can be easily achieved by properly placing the electrodes, as demonstrated in the present study.

关键词： Hot stamping Electrically assisted rapid heating Partial austenization Al–Si-coated hot stamping steel

Effect of hydrogen fluoride and magnesium oxide on AZ31 Mg alloy/carbon fiber-reinforced plastic composite by thermal laser joining technique

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journal of Magnesium and Alloys 2024年第7期12卷 2874-2889页

作者： Andrews Nsiah Ashong Barton Mensah Arkhurst Youn Seoung lee Mok-Young lee Jeoung han Kim School of Materials Science&Engineering University of New South Wales SydneyNSW2052Australia Department of Information and Communication Engineering Hanbat National UniversityYuseong-guDaejeonSouth Korea Welding&joining research group steel solution research laboratoryPOSCOIncheonRepublic of Korea Department of Materials Science&Engineering Hanbat National UniversityYuseong-guDaejeonSouth Korea

Although hydrofluoric acid(HF)surface treatment is known to enhance the joining of metals with polymers,there is limited information on its effect on the joining of AZ31 alloy and carbon-fiber-reinforced plastics(CFRPs)through laser-assisted metal and plastic direct joining(LAMP).This study uses the LAMP technique to produce AZ31-CFRP *** joining process involves as-received AZ31,HFpretreated AZ31,and thermally oxidized HF-pretreated AZ31 alloy ***,the bonding strength of joints prepared with thermally oxidized AZ31 alloy sheets is examined to ascertain the combined effect of HF treatment and thermal oxidation on bonding *** microstructures,surface chemical interactions,and mechanical performances of joints are investigated under tensile shear *** factors,such as bubble formation,CFRP resin decomposition,and mechanical interlocking considerably affect joint ***,surface chemical interactions between the active species on metal parts and the polar amide along with carbonyl groups of polymer play a significant role in improving joint *** prepared with surface-pretreated AZ31 alloy sheets show significant improvements in bonding strength.

关键词： Thermal laser joining Thermal oxidation Hydrofluoric acid pretreatment Mechanical interlocking Covalent bonds Chemical interactions

All-fiber acousto-optic modulator based on a cladding-etched optical fiber for active mode-locking

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Photonics Research 2017年第5期5卷 391-395页

作者： JIHWAN KIM joONHOI KOO JU han lee School of Electrical and Computer Engineering University of Seoul

An all-fiber acousto-optic modulator(AOM), which features a compact structure and a low-driving voltage, is experimentally demonstrated for the active mode-locking of a fiber laser. The proposed AOM is based on the short length of the cladding-etched fiber, the ends of which are fixed on a slide glass. On top of the cladding-etched fiber, a piezoelectric transducer was overlaid. A chemical wet-etching technique, which is based on a mixed solution of NH_4F and (NH_4)2SO_4, is used to reduce the fiber diameter down to ～25 μm, and the length of the etched section is only 0.5 cm. The fabricated device exhibited a modulation depth of 73.10% at an acoustic frequency of 918.9 kHz and a peak-to-peak electrical voltage of 10 V, while a laser beam was coupled at 1560 *** using the prepared AOM within an erbium-doped-fiber ring cavity, the mode-locked pulses with a temporalwidth of 2.66 ps were readily obtained at a repetition rate of 1.838 MHz.

关键词： All-fiber acousto-optic modulator based on a cladding-etched optical fiber for active mode-locking

Ecotoxicity evaluation of Cu-and Fe-CNT complexes based on the activity of bacterial bioluminescence and seed germination

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journal of Environmental Sciences 2018年第5期30卷 198-205页

作者： In Chul Kong Kyung Seok Ko Mun Hui lee Ji Hwoan lee Young-Hwan han Department of Environmental Engineering Yeungnam UniversityGyungsan 38541Republic of Korea Geologic Environment Division Korea Institute of Geoscience and Mineral Resources(KIGAM)Daejeon 34132Republic of Korea School of Materials Science and Engineering Yeungnam University Gyungsan 38541Republic of Korea International School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430079China

The toxic effects of the composites of Fe^0 and Cu^0 with different percentages of CNTs were examined based on the activity of bacterial bioluminescence and seed germination. In terms of the EC50 values, the toxic effects of Cu^0 on bacterial bioluminescence and seed germination were approximately 2 and 180 times greater than that of Fe^0, respectively. The toxicity increased with increasing CNT content in the Cu-CNT mixtures for both organisms,whereas opposite results were observed with Fe-CNT mixtures. The mean toxic effects of Cu-CNT（6%） were approximately 1.3–1.4 times greater than that of Cu-CNT（0%）, whereas the toxic effects of Fe-CNT（6%） were approximately 2.1–2.5 times lower than that of Fe-CNT（0%） for both the bioluminescence activity and seed germination. The causes of this phenomenon are unclear at this point. More research will be needed to elucidate the mechanism of the toxicity of nano-mixture materials and the causes of the different patterns of toxicity with Cu-and Fe-CNT mixtures.

关键词： Metal-CNT complex Bioluminescence Seed germination Toxic effect

THE PHYSICAL PROPERTIES OF POLY(2-HYDROXYETHYL METHACRYLATE)COPOLYMER HYDROGELS USED AS INTRAVAGINAL RINGS

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Chinese journal of Polymer Science 2009年第3期27卷 359-366页

作者： Young A han Eun Mi lee Byung Chul Ji Department of Textile System Engineering Kyungpook National UniversityDaegu 702-701Korea Department of Advanced Organic Materials Science and Engineering Kyungpook National UniversityDaegu 702-701Korea

Poly(2-hydroxyethyl methacrylate)(PHEMA)and poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) [P(HEMA-co-SMA)]hydrogels with different compositions were prepared to be used as intravaginal rings,and their gelation time,water content,mechanical properties and morphology were *** water content of PHEMA and P(HEMA-co-SMA) hydrogels decreased as the concentration of the monomer and the degree of crosslinking increased,while the water content significantly increased as the content of SMA,the hydrophilic monomer,*** increasing of the concentration of the crosslinking agent affected the tensile and flexural properties *** presence of a proper small amount of SMA also led the tensile and flexural modulus to move to a higher *** results showed that P(HEMA-co-SMA) hydrogel with high drug load and good mechanical properties at optimum preparation conditions can be prepared for intravaginal rings to deliver nonhormonal *** results may be applied to prepare better intravaginal drug delivery devices.

关键词： PHEMA and P(HEMA-co-SMA)hydrogels Tensile and flexural properties High drug load Intravaginal drug delivery devices.

Precise control of surface oxygen vacancies in ZnO nanoparticles for extremely high acetone sensing response

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journal of Advanced Ceramics 2022年第5期11卷 769-783页

作者： Jihyun lee Youngmoon CHOI Byoung joon PARK Jeong Woo han Hyun-Sook lee jong Hyeok PARK Wooyoung lee Department of Materials Science and Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Chemical and Biological Engineering Yonsei UniversitySeoul 03722Republic of Korea Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673Republic of Korea Institute for Convergence Research and Education in Advanced Technology Yonsei UniversitySeoul 03722Republic of Korea

ZnO has been studied intensely for chemical sensors due to its high sensitivity and fast ***,we present a simple approach to precisely control oxygen vacancy contents to provide significantly enhanced acetone sensing performance of commercial ZnO nanopowders.A combination of H_(2)O_(2)treatment and thermal annealing produces optimal surface defects with oxygen vacancies on the ZnO nanoparticles(NPs).The highest response of~27,562 was achieved for 10 ppm acetone in 0.125 MH_(2)O_(2)treated/annealed ZnO NPs at the optimal working temperature of 400℃,which is significantly higher than that of reported so far in various acetone sensors based on metal oxide semiconductors(MOSs).Furthermore,first-principles calculations indicate that pre-adsorbed O formed on the surface of H_(2)O_(2)treated ZnO NPs can provide favorable adsorption energy,especially for acetone detection,due to strong bidentate bonding between carbonyl C atom of acetone molecules and pre-adsorbed O on the ZnO *** study demonstrates that controlling surface oxygen vacancies by H_(2)O_(2)treatment and re-annealing at optimal temperature is an effective method to improve the sensing properties of commercial MOS materials.

关键词： gas sensors acetone metal oxide semiconductors(MOSs) ZnO nanoparticles(NPs) H_(2)O_(2)treatment