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In-Hospital outcomes in Minimally Invasive Mitral Valve Surgery: First Results in a Brazilian Single Center

open journal of Thoracic Surgery 2024年第1期14卷 17-28页

作者： Daniel de Magalhães Freitas joão alber.o pansani Max Weyler Nery Stanlley de oliveira Loyola Maurício Lopes Prudente Giulliano Gardenghi Artur Henrique de Souza Department of Cardiovascular Surgery Encore Hospital Aparecida de Goiania Brazil Anesthesia Clinic (Clianest) Goiania Brazil

Introduction: Treatments for cardiovascular diseases have increasingly evolved with the tendency to offer minimally invasive or transcatheter procedures instead of conventional sternotomy surgery. In this context, we highlight minimally invasive mitral valve surgery (MIMVS), which has been shown to be an increasingly solid option with some superior results when compared to the conventional technique: better pain control, shorter hospital stays, shorter recovery time, shorter readmission rate in the first postoperative year, better aesthetic results, and lower overall cost. Aim: This study aims to evaluate the stages of MIMVS, by primary mitral valve consultation, in our service and compare these results with data from the literature. Methods: All electronic medical records of patients who underwent MIMVS for primary mitral valve injury in the Encore Hospital from January 2020 to February 2023 were analyzed. Tabulation and statistical analysis were performed using the Microsoft Excel® program. Quantitative variables were presented as means, standard deviations. Results: 46 patients were enrolled in our study (Age: 59.1 ± 12.4 years old;60.8% Female, BMI: 26 ± 4.4 Kg/m2, Low risk STS score: 82.6%). The observed 30-day mortality was 2.1%, plastic rate of 23.9%, blood transfusion rate of 41.3%, length of stay in an intensive care bed (ICB) of 3.3 ± 3.3 days and hospital stay of 6.4 ± 5.1 days. Conclusions: We noticed that the MIMVS results carried out in our service agree with data from national and international literature with approximately 1.3 days more hospitalization in ICB.

关键词： Minimally Invasive Surgical Procedures Mitral Valve outcome Assessment Health Care

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In-Hospital outcomes in Minimally Invasive Mitral Valve Surgery: First Results in a Brazilian Single Center

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open journal of Thoracic Surgery（胸外科期刊） 2024年第1期 17页

作者： Daniel de Magalhães Freitas joão alber.o pansani Max Weyler Nery Stanlley de oliveira Loyola Maurício Lopes Prudente Giulliano Gardenghi Artur Henrique de Souza

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Increased basal plasma brain-derived neurotrophic factor levels in sprint runners

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Neuroscience Bulletin 2011年第5期27卷 325-329页

作者： Paulo Roberto Correia Fulvio Alexandre Scorza Sérgio Gomes da Silva Aline pansani Michelle Toscano-Silva Antonio Carlos de Almeida Ricardo Mario Arida 圣保罗联邦大学生理学系圣保罗联邦大学神经内外科系 So joo del-Rei联邦大学实验与计算神经生物学实验室

objective Exercise is known to enhance circulating brain-derived neurotrophic factor （BDNF） levels in healthy humans. BDNF changes have been measured in endurance but not in strength exercise. The present study aimed to investigate whether anaerobic activity such as sprinting differentially alters basal plasma BDNF concentration. Methods Brazilian sprinters （100 m） at either the international （olympics and outdoor World Championships）（n = 14） or the domestic level （n = 8）, and sedentary subjects （n = 15）, were recruited. Plasma BDNF concentrations were analyzed by enzyme-linked immunosorbent assay. Results The basal plasma BDNF concentrations were significantly higher in the international and the domestic sprinters than in the sedentary subjects. In addition, sprinters at the international level had higher plasma BDNF concentrations than those at the domestic level. Conclusion our findings suggest that increased basal plasma BDNF level is related to enhanced exercise performance.

关键词： brain-derived neurotrophic factor physical exercise sprint plasma brain human

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