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Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第3期12卷 189-192页

作者： Yuan-qiang LU jiu-kun JIANG wei-dong HUANG Department of Emergency the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China

Objective:To report clinical features and treatment of 16 cases of acute 2,4-dinitrophenol poisoning. Methods:A total of 16 patients suffering from acute poisoning due to non-oral exposure to 2,4-dinitrophenol were sent to our *** died within 3 h after admission,while the other 14 responded to supportive treatment and *** features and treatment of the patients were retrospectively analyzed and ***:Fourteen patients recovered and were discharged after four to six weeks of *** obvious poisoning sequelae were found in the three-month ***:Non-oral exposure to 2,4-dinitrophenol is *** and glucocorticoid treatments may be efficient measures to prevent mortality,but this requires further study.

关键词： 2 4-Dinitrophenol Poisoning Therapeutics Hemoperfusion Glucocorticoid

Approximate expression of Young's equation and molecular dynamics simulation for its applicability

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Chinese Physics B 2019年第1期28卷 527-531页

作者： Shu-Wen Cui jiu-an wei wei-wei Liu Ru-Zeng Zhu Qian Ping Department of Physics and Information Engineering Cangzhou Normal University State Key Laboratory of Nonlinear Mechanics(LNM)and Key Laboratory of Microgravity Institute of MechanicsChinese Academy of Science Silfex a Division of Lam Research Department of Physics University of Science and Technology Beijing

In 1805, Thomas Young was the first to propose an equation(Young's equation) to predict the value of the equilibrium contact angle of a liquid on a solid. On the basis of our predecessors, we further clarify that the contact angle in Young's equation refers to the super-nano contact angle. Whether the equation is applicable to nanoscale systems remains an open question. Zhu et al. [College Phys. 4 7(1985)] obtained the most simple and convenient approximate formula, known as the Zhu–Qian approximate formula of Young's equation. Here, using molecular dynamics simulation, we test its applicability for nanodrops. Molecular dynamics simulations are performed on argon liquid cylinders placed on a solid surface under a temperature of 90 K, using Lennard–Jones potentials for the interaction between liquid molecules and between a liquid molecule and a solid molecule with the variable coefficient of strength a. Eight values of a between 0.650 and 0.825 are used. By comparison of the super-nano contact angles obtained from molecular dynamics simulation and the Zhu–Qian approximate formula of Young's equation, we find that it is qualitatively applicable for nanoscale systems.

关键词： molecular dynamics simulation Young’s equation surface tension Zhu–Qian approximate formula of Young’s equation

Regulating monocyte infiltration and differentiation:Providing new therapies for colorectal cancer patients with COVID-19

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World Journal of Clinical Cases 2021年第34期9卷 10392-10399页

作者： Ling Bai Wang Yang Lei Qian jiu-wei Cui Cancer Center The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

The outbreak of coronavirus disease 2019(COVID-19)is a significant challenge for clinicians,especially for immunocompromised cancer *** analyzing the impact of COVID-19 on the immune microenvironment of colorectal cancer(CRC)patients at the tissue level and single-cell level,we found that CRC patients are more easily infected by severe acute respiratory syndrome coronavirus-2(SARSCoV-2),but promotion of infiltration and differentiation of monocytes makes them more likely to develop severe *** of the continuing activation of nuclear factor(NF)-κB and C-C chemokine receptor type 5(CCR5)signaling pathways in monocytes,imbalance of macrophage polarization can aggravate the cytokine release ***,regulating the infiltration and differentiation of monocytes is helpful for the treatment of COVID-19 in CRC patients.

关键词： COVID-19 SARS-CoV-2 Monocyte Macrophage Colorectal cancer

Tolman length of simple droplet: Theoretical study and molecular dynamics simulation

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Chinese Physics B 2021年第1期30卷 443-448页

作者： Shu-Wen Cui jiu-an wei Qiang Li wei-wei Liu Ping Qian Xiao Song Wang Department of Physics and Information Engineering Cangzhou Normal UniversityCangzhou 061001China State Key Laboratory of Nonlinear Mechanics(LNM)and Key Laboratory of Microgravity Institute of MechanicsChinese Academy of SciencesBeijing 100190China Silfex a Division of Lam Research950 South Franklin StreetEatonOhio 45320USA Department of Physics University of Science and Technology BeijingBeijing 100083China Institute of Mechanics and Power Engineering Henan Polytechnic UniversityJiaozuo 454003China

In 1949, Tolman found the relation between the surface tension and Tolman length, which determines the dimensional effect of the surface tension. Tolman length is the difference between the equimolar surface and the surface of tension. In recent years, the magnitude, expression, and sign of the Tolman length remain an open question. An incompressible and homogeneous liquid droplet model is proposed and the approximate expression and sign for Tolman length are derived in this paper. We obtain the relation between Tolman length and the radius of the surface of tension(R_(s)) and found that they increase with the Rs decreasing. The Tolman length of plane surface tends to zero. Taking argon for example, molecular dynamics simulation is carried out by using the Lennard–Jones(LJ) potential between atoms at a temperature of 90 K. Five simulated systems are used, with numbers of argon atoms being 10140, 10935, 11760, 13500, and 15360, respectively. By methods of theoretical study and molecular dynamics simulation, we find that the calculated value of Tolman length is more than zero, and it decreases as the size is increased among the whole size range. The value of surface tension increases with the radius of the surface of tension increasing, which is consistent with Tolman’s theory. These conclusions are significant for studying the size dependence of the surface tension.

关键词： Tolman length surface tension radius of surface of tension radius of equimolecular surface molecular dynamics simulation

Synergistic effect of chloride ion and albumin on the corrosion of pure magnesium

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Frontiers of Materials Science 2014年第3期8卷 244-255页

作者： Cheng-Long LIU Yi ZHANG Chun-Yan ZHANG wei WANG wei-jiu HUANG Paul K. CHU School of Materials Science and Engineering Chongqing University of Technology Chongqing 400050 China Department of Physics and Materials Science City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong China

In this work, we report on synergistic effect of chloride ion and albumin on the corrosion of pure magnesium through corrosion tests. We show that the adsorption of albumin mainly affects the anodic polarization behavior of pure magnesium in NaCl solution. Low concentration of albumin enhances the reaction reactivity of pure magnesium and the initial evolvement of hydrogen at the initial immersion time. Addition of I glL albumin provides limited corrosion control for pure magnesium in NaCl solution. In comparison with low concentration albumin, addition of 10 g/L albumin can effectively inhibit the further dissolution of pure magnesium in test solutions with NaCI concentration of 0.2-0.8 wt. %, but this effect lowers gradually with increasing the concentration of chloride ion.

关键词： magnesium corrosion albumin biomaterial

A STUDY ON CHINESE TERTHREUTIS MEYRICK (LEPID OPTERA: TORTRICIDAE), WITH DESCRIPTION OF NEW SPECIES

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昆虫学报 1992年第3期 343-345页

作者： BAI jiu-wei (Institute of Zoology, Academia Sinica)

The genus Terthreutis Meyrick, 1918(Tortricidae) with curious abnormal appearance, perhaps allied to Coephasia. Until now 3 known species recorded in theworld, only distributed in China and India.

关键词： LEPID OPTERA TORTRICIDAE WITH DESCRIPTION OF NEW SPECIES A STUDY ON CHINESE TERTHREUTIS MEYRICK

Diverse and precision therapies open new horizons for patients with advanced pancreatic ductal adenocarcinoma

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Hepatobiliary & Pancreatic Diseases International 2022年第1期21卷 10-24页

作者： Ri-Lan Bai Nan-Ya Wang Ling-Ling Zhao Yong-Fei Zhang jiu-wei Cui Cancer Center the First Hospital of Jilin UniversityChangchun 130021China

Pancreatic ductal adenocarcinoma(PDAC)is a common cause of cancer-related death,and most patients are with advanced disease when *** present,despite a variety of treatments have been devel-oped for PDAC,few effective treatment options are available;on the other hand,PDAC shows significant resistance to chemoradiotherapy,targeted therapy,and immunotherapy due to its heterogeneous genetic profile,molecular signaling pathways,and complex tumor immune ***,over the past decades,there have been many new advances in the key theory and understanding of the in-trinsic mechanisms and complexity of molecular biology and molecular immunology in pancreatic can-cer,based on which more and more diverse new means and reasonable combination strategies for PDAC treatment have been developed and preliminary breakthroughs have been *** the continuous ex-ploration,from surgical local treatment to comprehensive medical management,the research-diagnosis-management system of pancreatic cancer is *** review focused on the variety of treatments for advanced PDAC,including traditional chemotherapy,targeted therapy,immunotherapy,microenviron-ment matrix regulation as well as the treatment targeting epigenetics,metabolism and cancer stem *** pointed out the current research bottlenecks and future exploration directions.

关键词： Tumor Pancreatic ductal adenocarcinoma Targeted therapy Immunotherapy Epigenetics Tumor microenvironment

EBSD Study of Microstructural and Textural Changes of Hot-Rolled Ti–6Al–4V Sheet After Annealing at 800 ℃

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Acta Metallurgica Sinica(English Letters) 2018年第11期31卷 1215-1223页

作者： Ji-Ying Xia Lin-Jiang Chai Hao Wu Yan Zhi Yin-Ning Gou wei-jiu Huang Ning Guo College of Materials Science and Engineering Chongqing University of Technology Faculty of Materials and Energy Southwest University

In this paper, electron backscatter diffraction and various other characterization and analysis techniques mclucilng X-raydiffraction, electron channeling contrast imaging and energy-dispersive spectrometry were jointly employed to investigatemicrostructural and textural changes of a hot-rolled Ti-6A1-4V （TC4） sheet after annealing at 800 ℃ for 5 h. In addition,the hardness variation induced by the annealing treatment is rationalized based on revealed microstructural and texturalcharacteristics. Results show that the TC4 sheet presents a typical dual-phase （α＋β） microstructure, with α-Ti as themajor phase and short-rod-shaped β-Ti （minority） uniformly distributed throughout the α matrix. Most of α grains cor-respond to the un-recrystallized structures with a typical rolling texture （c//TD and 〈11-20〉//ND） and dense low angleboundaries （LABs）. After the annealing, the stored energy in the as-received specimen is significantly reduced, along withgreatly decreased LABs density. Also, the annealing allows recrystallization and grain growth to occur, leading toweakening of the initial texture. Furthermore, the water quenching immediately after the annealing triggers martensitictransformation, which makes the high-temperature β phases be transformed into submicron α plates. The hardness of theannealed specimen is 320.5 HV, lower than that （367.0 HV） of the as-received specimen, which could be attributed toreduced LABs, grain growth and weakened texture. Nevertheless, the hardening effect from the fine martensitic platescould help to suppress a drastic hardness drop.

关键词： Ti alloy Electron backscatter diffraction Recrystallization Texture - Hardness

Mechanism of mine water-inrush through a fault from the floor

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Mining Science and Technology 2009年第3期19卷 276-281页

作者： HAN Jin SHI Long-qing YU Xiao-ge wei jiu-chuan LI Shu-cai College of lnformation Science and Engineering Shandong University of Science and Technology Qingdao Shandong 266510 China Geotechnical ＆ Structural Engineering Technique Center Ji＇nan Shandong 250061 China

The mechanism of mine water inrushes in coal mines in China differs considerably from that in other *** China, most water inrushes occur from floor strata, where the water-inrush sources are karstic limestone *** study describes the mechanism of mine water inrushes through a fault in the mine floor using principles of strata mechanics and the path of water inrush from an aquifer to the working face.A criterion to judge whether a ground water inrush will occur through a fault or not is also described, together with a case history of water inflow in the Feicheng coalfield, China.

关键词： fault water-inrush mechanism Feicheng coalfield