检索结果-南通市图书馆

Advancing microarray fabrication:One-pot synthesis and highresolution patterning of UV-crosslinkable perovskite quantum dots

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第9期17卷 8600-8609页

作者： Linfeng Yuan Dejian Chen Kun He Jiamin xu Kunyuan xu Jie Hu Sisi Liang Haomiao Zhu CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Key Laboratory of Nanomaterials Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108China University of Chinese Academy of Sciences Beijing 100049China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350007China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Research Center of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021China

The development of highly efficient,solution-processable,and environmentally stable perovskite quantum dots(PQDs)is crucial for their accurate high-resolution patterning and subsequently enabling the practical deployment of PQD based emissive display *** study presents an innovative strategy for integrating all-inorganic PQDs and ultraviolet(UV)crosslinkable acrylate polymer at a structural and functional *** achievement is accomplished by meticulous design and one-pot synthesis of UV-crosslinkable CsPbX_(3)(X=Cl,Br,I)PQDs solution,which exhibit outstanding environmental *** the solution-processable characteristics of the resulting UV-crosslinkable PQDs,precise patterning of high-resolution(2μm,7608 pixels·in.^(-1))and colorful PQDs microarrays can be readily achieved through inkjet printing and high-throughput photolithography(~2μm in pitch line/space patterning).The UV cross-linked process guarantees a homogeneous distribution of PQDs,effectively mitigating coffee ring effect and improving the overall quality of stereoscopic *** photo-cured PQDs film,which undergoes free radical photopolymerization,displays an impressive photoluminescence quantum yield(PL QY)of up to 89.2%,reaching 98%of the value observed in the solution *** approach outlined in this research is both cost-effective and pragmatic,exhibiting tremendous promise for diverse system-level integrated optoelectronic devices,such as ultra-high-resolution micro-light-emitting device(micro-LED)displays.

关键词： perovskite quantum dots microarrays cross-linking strategy Inkjet printing photolithography

Molecular Dynamics Numerical Simulation of Adsorption Characteristics and Exploitation Limits in Shale Oil Microscopic Pore Spaces

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fluid Dynamics & Materials Processing 2024年第8期20卷 1915-1924页

作者： Guochen xu Taizhou Oil Production Plant Sinopec East China Oil and Gas CompanyTaizhou225300China

Microscopic pore structure in continental shale oil reservoirs is characterized by small pore throats and complex *** adsorption behavior of hydrocarbons on the pore walls exhibits unique physical and chemical ***,studying the adsorption morphology of hydrocarbon components in nanometer-sized pores and clarifying the exploitation limits of shale oil at the microscopic level are of great practical significance for the efficient development of continental shale *** this study,molecular dynamics simulations were employed to investigate the adsorption characteristics of various single-component shale oils in inorganic quartz fissures,and the influence of pore size and shale oil hydrocarbon composition on the adsorption properties in the pores was *** results show that different molecules have different adsorption capacities in shale oil pores,with lighter hydrocarbon components(C6H14)exhibiting stronger adsorption *** the same adsorbed molecule,the adsorption amount linearly increases with the increase in pore diameter,but larger pores contribute more to shale oil *** shale pores,the thickness of the adsorption layer formed by shale oil molecules ranges from 0.4 to 0.5 nm,which is similar to the width of alkane *** oil in the adsorbed state that is difficult to be exploited is mainly concentrated in the first adsorption *** them,the volume fraction of adsorbed shale oil in 6 nm shale pores is 40.8%,while the volume fraction of shale oil that is difficult to be exploited is 16.2%.

关键词： Shale oil utilization limit micro adsorption molecular dynamics simulation

Coseismic Coulomb stress changes induced by a 2020-2021 M_(W)>7.0 Alaska earthquake sequence in and around the Shumagin gap and its influence on the Alaska-Aleutian subduction interface

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geodesy and Geodynamics 2024年第1期15卷 1-12页

作者： Lei Yang Jianjun Wang Caijun xu School of Geodesy and Geomatics Wuhan UniversityWuhan 430079China Collaborative Innovation Center of Geospatial Technology Wuhan 430079China Key Laboratory of Geospace Environment and Geodesy Ministry of EducationWuhan UniversityWuhan 430079China

Three M_(W)>7.0 earthquakes in 2020-2021 occurred in the Shumagin seismic gap and its adjacent area of the Alaska-Aleutian subduction zone,including the Mw7.8 Simeonof thrust earthquake on July 22,2020,the M_(W)7.6 Sand Point strike-slip earthquake on October 19,2020,and the M_(W)8.2 Chignik thrust earthquake on July 29,*** spatial and temporal proximity of these three earthquakes prompts us to probe stress-triggering effects among *** we examine the coseismic Coulomb stress change imparted by the three earthquakes and their influence on the subduction *** results show that:(1)The Simeonof earthquake has strong loading effects on the subsequent Sand Point and Chignik earthquakes,with the Coulomb stress changes of 3.95 bars and 2.89 bars,*** Coulomb stress change caused by the Sand Point earthquake at the hypocenter of the Chignik earthquake is merely around 0.01 bars,suggesting the negligible triggering effect on the latter earthquake;(2)The triggering effects of the Simeonof,Sand Point,and Chignik earthquakes on aftershocks within three months are not well pronounced because of the triggering rates of 38%,14%,and 43%*** factors may have played an important role in promoting the occurrence of these aftershocks,such as the roughness of the subduction interface,the complicated velocity structure of the lithosphere,and the heterogeneous prestress therein;(3)The three earthquakes caused remarkable coseismic Coulomb stress changes at the subduction interface nearby these mainshocks,with an average Coulomb stress change of 3.2 bars in the shallow region directly inwards the trench.

关键词： The 2020-2021 Alaska earthquake sequence Coseismic Coulomb stress change Mainshock-aftershock triggering The Alaska-Aleutian subduction interface The Shumagin gap

Piperazine-derived ionizable lipids for enhanced mRNA delivery and cancer immunotherapy

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第8期17卷 7357-7364页

作者： Kai xu Yujia xu Jin Sun Xinwei Cheng Chenxi Lu Wenzhong Chen Bingfang He Tianyue Jiang School of Pharmaceutical Sciences Nanjing Tech UniversityNanjing 211816China Department of Nano Formulation Nanjing GeneLeap BiotechnologyNanjing 210061China

Messenger ribonucleic acid(mRNA)-based therapeutics hold great prospects in disease treatment and lipid nanoparticles(LNPs)are the most extensively applied non-viral platform for RNA delivery in *** the clinical success of LNPs as vehicles have been achieved,developing LNPs with enhanced mRNA transmembrane delivery and transfection efficiency in a non-toxic manner is highly desirable and *** this study,we designed a series of new ionizable amino lipids with piperazinederived headgroups and constructed a group of LNPs to promote the transfection activity of mRNA *** them,LNP formulated with lipid 10(L10-LNP)can efficiently package mRNA and perform superior transfection efficiency both in vitro and in vivo,which is mainly attributed to the improved intracellular uptake and effective endosomal *** verified that a single administration of L10-LNP packaging interleukin(IL)-12 mRNA induced tumor shrink and even regression by robust activation of immune effector CD8^(+)T cells and stimulating the generation of IFN-γwithout causing systemic toxicity,which provides a promising platform for clinical cancer immunotherapy.

关键词： ionizable lipid lipid nanoparticle piperazine-derived lipid mRNA therapeutics cancer immunotherapy

A DIRECT DISCONTINUOUS GALERKIN METHOD FOR TIME FRACTIONAL DIFFUSION EQUATIONS WITH FRACTIONAL DYNAMIC BOUNDARY CONDITIONS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computational Mathematics 2024年第1期42卷 156-177页

作者： Jingjun Zhao Wenjiao Zhao Yang xu School of Mathematics Harbin Institute of TechnologyHarbin 150001China

This paper deals with the numerical approximation for the time fractional diffusion problem with fractional dynamic boundary *** well-posedness for the weak solutions is studied.A direct discontinuous Galerkin approach is used in spatial direction under the uniform meshes,together with a second-order Alikhanov scheme is utilized in temporal direction on the graded mesh,and then the fully discrete scheme is ***,the stability and the error estimate for the full scheme are analyzed in *** experiments are also given to illustrate the effectiveness of the proposed method.

关键词： Time fractional diffusion equation Numerical stability Convergence

Automatic Requirement Dependency Extraction Based on Integrated Active Learning Strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Machine Intelligence Research 2024年第5期21卷 993-1010页

作者： Hui Guan Guorong Cai Hang xu Department of Computer Science and Technology Shenyang University of Chemical TechnologyShenyang110142China Key Laboratory of Industrial Intelligence Technology on Chemical Process Shenyang110142China

Since requirement dependency extraction is a cognitively challenging and error-prone task,this paper proposes an automatic requirement dependency extraction method based on integrated active learning *** this paper,the coefficient of variation method was used to determine the corresponding weight of the impact factors from three different angles:uncertainty probability,text similarity difference degree and active learning variant prediction divergence *** combining the three factors with the proposed calculation formula to measure the information value of dependency pairs,the top K dependency pairs with the highest comprehensive evaluation value are selected as the optimal *** the optimal samples are continuously added into the initial training set,the performance of the active learning model using different dependency features for requirement dependency extraction is rapidly ***,compared with other active learning strategies,a higher evaluation measure of requirement dependency extraction can be achieved by using the same number of ***,the proposed method using the PV-DM dependency feature improves the weight-F1 by 2.71%,the weight-recall by 2.45%,and the weight-precision by 2.64%in comparison with other strategies,saving approximately 46%of the labelled data compared with the machine learning approach.

关键词： Requirement dependency dependency extraction dependency features integrated active learning strategies coefficient of variation

Design and simulation investigations on charge transport layers‑free in lead‑free three absorber layer all‑perovskite solar cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Optoelectronics 2024年第2期17卷 69-85页

作者： Guangdong Li Mingxiang xu Zhong Chen School of Physics Southeast UniversityNanjing 211189China

The multiple absorber layer perovskite solar cells(PSCs)with charge transport layers-free(CTLs-free)have drawn widespread research interest due to their simplified architecture and promising photoelectric *** the circumstances,the novel design of CTLs-free inversion PSCs with stable and nontoxic three absorber layers(triple Cs_(3)Bi_(2)I_(9),single MASnI_(3),double Cs_(2)TiBr_(6))as optical-harvester has been numerically simulated by utilizing wxAMPS simulation software and achieved high power conversion efficiency(PCE)of 14.8834%.This is owing to the innovative architecture of PSCs favors efficient transport and extraction of more holes and the slender band gap MASnI_(3)extends the absorption spectrum to the near-infrared periphery compared with the two absorber layers architecture of ***,the performance of the device with p-type-Cs_(3)Bi_(2)I_(9)/p-type-MASnI_(3)/n-type-Cs_(2)TiBr_(6)architecture is superior to the one with the p-type-Cs_(3)Bi_(2)I_(9)/ntype-MASnI_(3)/n-type-Cs_(2)TiBr_(6)architecture due to less carrier recombination and higher carrier life time inside the absorber *** simulation results reveal that Cs_(2)TiF_(6)double perovskite material stands out as the best ***,an excellent PCE of 21.4530%can be obtained with the thicker MASnI_(3)absorber layer thickness(0.4μm).Lastly,the highestperformance photovoltaic devices(28.6193%)can be created with the optimized perovskite doping density of around E15 cm^(3)(Cs_(3)Bi_(2)I_(9)),E18 cm^(3)(MASnI_(3)),and 1.5E19 cm^(3)(Cs_(2)TiBr_(6)).This work manifests that the proposed CTLs-free PSCs with multi-absorber layers shall be a relevant reference for forward applications in electro-optical and optoelectronic devices.

关键词： Multiple absorber layer PSCs CTLS-free·Inverted Narrow-band gap Simulation

Outlier Robust Feature Correspondence by Learning Based Matching Process

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2024年第4期37卷 1351-1367页

作者： YANG xu ZENG Shaofeng LIU Zhiyong State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of Automation of Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100190China

Feature correspondence is a crucial aspect of various computer vision and robot vision *** traditional optimization-based matching techniques,researchers have recently adopted a learning-based approach for matching,but these methods face challenges in dealing with outlier *** paper presents an outlier robust feature correspondence method that employs a pruned attentional graph neural network and a matching layer to address the outlier ***,the authors introduce a modified cross-entropy matching loss to handle the outlier *** a result,the proposed method significantly enhances the performance of learning-based matching algorithms in the presence of outlier *** experiments confirm the effectiveness of the proposed approach.

关键词： Feature correspondence graph neural network optimal transport problem pointmatching

Resolving the geometric structure of trastuzumab by mobility capillary electrophoresis and native mass spectrometry

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第3期35卷 221-225页

作者： Wenjing Zhang Jie Hong Lei Yang Zuqiang xu Yu Xiang Wei xu School of Life Science Beijing Institute of TechnologyBeijing 100081China

Available online Immunoglobulins G(IgGs)are Y-shaped globular proteins,however,their high flexibility and heterogeneity pose great challenges to their structure and conformation *** structure of IgG closely correlates to its biofunctions,such as the antibody escape of human immunodeficiency virus(HIV)could attribute to the distance mismatch between the ends of two Fab arms(antigen-binding sites)and envelope glycoprotein spikes on virion ***,we report the first use of mobility capillary electrophoresis(MCE)and native mass spectrometry(nMS)to resolve the internal geometric structure and conformation of an IgG(trastuzumab)in solution *** proteolysis,the ellipsoid dimensions of IgG and its subunits were measured by MCE-nMS *** was then reconstructed,in which the sizes and relative positions of these three subunits in three-dimensional space were *** was found that the two Fab arms have an angle of~102.1°and a distance of~11.0 nm between the two antigen-binding sites under native condition,and the Fc arm was tilted~16.0°towards one of the Fab *** was not on the plane of Fab-Fab,but has an angle of no larger than 103.1°.Under acidic environment(pH 3.0),each subunit of the IgG would unfold into larger dimensions,and the angles between these subunits also *** great potential for tumor imaging and therapy,the structure of F(ab')_(2)fragments was also measured and validated by molecular dynamic *** was found that the electrostatic force among these three subunits and steric hindrance stemming from Fc help maintaining the angle between two Fab arms.

关键词： Native mass spectrometry Mobility capillary electrophoresis Trastuzumab Protein structure Geometric structure