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Defence Technology（防务技术） 2024年第3期33卷 125-133页

作者： jinsong tang Linfang Qian Longmiao Chen Guangsong Chen Mingming Wang Guangzu Zhou Nanjing University of Science and Technology Nanjing 210094China Northwest Institute of Mechanical and Electrical Engineering Xianyang 712099China

In this paper,a dynamic modeling method of motor driven electromechanical system is presented,and the uncertainty quantification of mechanism motion is investigated based on this method.The main contribution is to propose a novel mechanism-motor coupling dynamic modeling method,in which the relationship between mechanism motion and motor rotation is established according to the geometric coordination of the system.The advantages of this include establishing intuitive coupling between the mechanism and motor,facilitating the discussion for the influence of both mechanical and electrical parameters on the mechanism,and enabling dynamic simulation with controller to take the randomness of the electric load into account.Dynamic simulation considering feedback control of ammunition delivery system is carried out,and the feasibility of the model is verified experimentally.Based on probability density evolution theory,we comprehensively discuss the effects of system parameters on mechanism motion from the perspective of uncertainty quantization.Our work can not only provide guidance for engineering design of ammunition delivery mechanism,but also provide theoretical support for modeling and uncertainty quantification research of mechatronics system.

关键词： Ammunition delivery system Electromechanical coupling dynamics Uncertainty quantification Generalized probability density evolution

General design principle of artillery for firing accuracy

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Defence Technology（防务技术） 2022年第12期18卷 2125-2140页

作者： Linfang Qian Guangsong Chen Minghao Tong jinsong tang School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing210094China

In this paper,based on the topological description method,the kinematic and dynamic equations of the projectile flight and projectile-artillery coupling system during the whole process of firing are constructed.The factors that can affect the projectile burst points,namely the state parameters of the projectile on the muzzle and state parameters of the barrel muzzle,as well as the factors that affect the barrel muzzle state parameters,are analyzed.On this basis,the design principle of artillery firing accuracy is proposed.The error analysis and the corresponding inverse problem,the extraction method of key parameters affecting artillery implicated motion,the conformal and control method of rotating band are analyzed and presented.Finally,the presented method is verified through a vehicle mounted howitzer case,and the muzzle state parameter interval is obtained meeting the given firing accuracy.In addition,the sensitivity analysis of artillery parameters shows that the less the correlation between the parameters and the barrel,the less the influence on the projectile implicated motion.The analysis of the coupling effect between rifling and the rotating band shows that the uniform rifling is the optimal form for the conformal of the rotating band during firing.

关键词： Firing accuracy Projectile-artillery coupling Rotating band conformal Sensitivity analysis Error control

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice

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Journal of Genetics and Genomics 2024年第4期51卷 407-418页

作者： Yaling Wang Xueying Huang Guoying Sun Jingwen Chen Bangguo Wu Jiahui Luo Shuyan tang Peng Dai Feng Zhang jinsong Li Lingbo Wang Shanghai Key Laboratory of Metabolic Remodeling and Health Institute of Metabolism and Integrative BiologyFudan UniversityShanghai 200438China Institute of Reproduction and Development Obstetrics and Gynecology HospitalFudan UniversityShanghai 200011China Shanghai Key Laboratory of Maternal and Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China State Key Laboratory of Cell Biology CAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesShanghai 200031China

During spermiogenesis,haploid spermatids undergo dramatic morphological changes to form slender sperm flagella and cap-like acrosomes,which are required for successful fertilization.Severe deformities in flagella cause a male infertility syndrome,multiple morphological abnormalities of the flagella(MMAF),while acrosomal hypoplasia in some cases leads to sub-optimal embryonic developmental potential.However,evidence regarding the occurrence of acrosomal hypoplasia in MMAF is limited.Here,we report the generation of base-edited mice knocked out for coiled-coil domain-containing 38(Ccdc38)via inducing a nonsense mutation and find that the males are infertile.The Ccdc38-KO sperm display acrosomal hypoplasia and typical MMAF phenotypes.We find that the acrosomal membrane is loosely anchored to the nucleus and fibrous sheaths are disorganized in Ccdc38-KO sperm.Further analyses reveal that Ccdc38 knockout causes a decreased level of TEKT3,a protein associated with acrosome biogenesis,in testes and an aberrant distribution of TEKT3 in sperm.We finally show that intracytoplasmic sperm injection overcomes Ccdc38-related infertility.Our study thus reveals a previously unknown role for CCDC38 in acrosome biogenesis and provides additional evidence for the occurrence of acrosomal hypoplasia in MMAF.

关键词： Acrosomal hypoplasia Multiple morphological abnormalities of the flagella(MMAF) Infertility Sperm motility Asthenoteratozoospermia Disease modeling

多子阵SAS六自由度运动补偿与成像快速算法

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华中科技大学学报（自然科学版） 2024年第3期52卷 28-34页

作者：田振钟何平唐劲松海军工程大学电子工程学院湖北武汉430033

针对多子阵合成孔径声纳(SAS)六自由度运动误差补偿及逐点运动补偿算法效率低的问题,提出一种能够快速补偿方位空不变六自由度运动误差的多子阵SAS运动补偿与成像算法.建立方位空不变六自由度运动误差存在情形下的多子阵SAS双根号形式... 详细信息

针对多子阵合成孔径声纳(SAS)六自由度运动误差补偿及逐点运动补偿算法效率低的问题,提出一种能够快速补偿方位空不变六自由度运动误差的多子阵SAS运动补偿与成像算法.建立方位空不变六自由度运动误差存在情形下的多子阵SAS双根号形式距离历程,利用泰勒级数展开对双根号形式距离历程进行近似并保留至方位时间的四阶项,利用级数反演方法推导出严格解析的点目标响应二维谱,进而提出能够快速实现方位空不变六自由度运动误差补偿与高分辨成像的距离多普勒算法.仿真试验和实测数据成像表明了所提算法的有效性.

关键词：合成孔径声纳运动补偿成像技术距离多普勒算法六自由度运动误差

Consensus of Chinese experts on glioma multidisciplinary team management (2nd edition)

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中华医学杂志(英文版) 2024年第11期137卷 1267-1270页

作者： Wu jinsong Zhou Zhirui Wu Zanyi tang Zhiwei Li Ming Yin Siyuan Luo Xufei Wang Ling Chen Yaolong Zhao Guoguang Jiang Tao Mao Ying The National Glioma MDT Alliance of National Center for Neurological Diseases Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing China Department of Neurosurgery Huashan Hospital Shanghai Medical College Fudan University Shanghai China Department of Radiation Oncology Huashan Hospital Shanghai Medical College Fudan University Shanghai China Department of Neurosurgery The First Affiliated Hospital of Fujian Medical University Fuzhou Fujian China Neurosurgery Department The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China Department of Neurosurgery Henan Provincial People’s Hospital People’s Hospital of Zhengzhou University Zhengzhou Henan China State Key Laboratory of Pharmaceutical Biotechnology Institute for Brain Sciences Advanced Institute for Life Sciences School of Life Sciences Nanjing University Nanjing Jiangsu China Evidence-Based Medicine Center School of Basic Medical Sciences Lanzhou University Lanzhou Gansu China School of Public Health Lanzhou University Lanzhou Gansu China Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China

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基于卷积神经网络的多偏移干涉相位滤波方法

北京航空航天大学学报 2024年第6期50卷 2043-2050页

作者：李涵钟何平张鹏唐劲松海军工程大学电子工程学院武汉430030 国防科技大学气象与海洋学院长沙410073

为提升干涉信号处理中相位滤波的效果,提出了一种基于卷积神经网络的多偏移干涉相位滤波方法。利用干涉相位噪声模型解释了相位偏移原理,并根据相位偏移原理构建多个卷积神经网络去噪器,利用其分别对不同偏移的干涉相位进行滤波,生成多... 详细信息

为提升干涉信号处理中相位滤波的效果,提出了一种基于卷积神经网络的多偏移干涉相位滤波方法。利用干涉相位噪声模型解释了相位偏移原理,并根据相位偏移原理构建多个卷积神经网络去噪器,利用其分别对不同偏移的干涉相位进行滤波,生成多个去噪相位。利用神经网络计算像素权值,对多个去噪结果进行融合,进而获得质量更好的相位滤波结果。仿真的数据和真实的数据试验表明,相较于传统方法,所提方法具有更好的细节保持能力,并且所得结果的均方根误差和留数点数量更低。

关键词：干涉信号处理相位滤波卷积神经网络噪声模型干涉相位

Solution-Processed Hybrid Europium (Ⅱ) lodide Scintillator for Sensitive X-Ray Detection

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Research 2024年第1期2024卷 49-57页

作者： Xue Zhao Pengfei Fu Pan Li Hainan Du jinsong Zhu Ciyu Ge Longbo Yang Boxiang Song Haodi Wu Tong Jin Qingxun Guo Liang Wang Jinghui Li Zewen Xiao Jingjing Chang Guangda Niu Jiajun Luo Jiang tang School of Microelectronics Xidian UniversityXi'an 710071China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China China Optics Valley Laboratory Wuhan 430074China School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China

Lead halide perovskite nanocrystals have recently demonstrated great potential as x-ray scintillators,yet they stll suffer toxicity issues,inferior light yield(LY)caused by severe self-absorption.Nontoxic bivalent europium ions(Eu^(2+))with intrinsically efficient and self-absorption-free d-f transition are a prospective replacement for the toxic Pb^(2+).Here,we demonstrated solution-processed organic-inorganic hybrid halide BA_(10)Eul_(12)(BA denotes C_(4)H_(9)NH_(4)^(+))single crystals for the first time.

关键词： absorption halide perovskite

基于贝叶斯网络强化学习的复杂装备维修排故策略生成

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北京航空航天大学学报 2024年第4期50卷 1354-1364页

作者：刘宝鼎于劲松韩丹阳唐荻音李鑫北京航空航天大学自动化科学与电气工程学院北京100191 北京航空航天大学仪器科学与光电工程学院北京100191 中国运载火箭技术研究院北京100076

为解决传统启发式维修排故决策方法决策时间长、生成策略总成本高的问题,提出一种基于贝叶斯网络(BN)结合强化学习(RL)进行复杂装备维修排故策略生成方法。为更好地利用复杂装备模型知识,使用BN进行维修排故知识表述,并且为更加贴近复... 详细信息

为解决传统启发式维修排故决策方法决策时间长、生成策略总成本高的问题,提出一种基于贝叶斯网络(BN)结合强化学习(RL)进行复杂装备维修排故策略生成方法。为更好地利用复杂装备模型知识,使用BN进行维修排故知识表述,并且为更加贴近复杂装备实际情况,依据故障模式、影响和危害性分析(FMECA)的故障概率,经合理转化后作为BN的先验概率;为使用RL的决策过程生成维修排故策略,提出一种维修排故决策问题转化为RL问题的方法;为更好地求解转化得到的强化学习问题,引入观测-修复动作对(O-A)以减小问题规模,并设置动作掩码处理动态动作空间。仿真结果表明:在统一的性能指标下,所提BN-RL方法较传统方法获得更高的指标值,证明该方法的有效性和优越性。

关键词：强化学习贝叶斯网络维修排故策略生成复杂装备动态动作空间

Impact of depression on the quality of sleep and immune functions in patients with coronary artery disease

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General Psychiatry 2022年第6期35卷 389-395页

作者： Liqiang Cai Lili Wei Jiashu Yao Yanhua Qin Yafeng You Luoyi Xu jinsong tang Wei Chen Department of Psychiatry Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiangChina

Background The risk of major depressive disorder(MDD)and insomnia is higher in patients with coronary heart disease(CHD)than in the general population.In addition,immune inflammation may be a shared aetiological factor for mental disorders and CHD.However,it is unclear whether MDD is associated with poor sleep quality and cell-mediated immune function in patients with CHD.Aims This study investigated the impact of depression/on sleep quality and cell-mediated immune functions in patients with CHD and examined discriminative factors in patients with CHD with and without MDD.Methods This cross-sectional retrospective study was conducted at the Zhejiang University School of Medicine afiliated with Sir Run Run Shaw Hospital.The study population consisted of 84 patients with CHD assigned to two groups based on their Hamilton Depression Rating Scale(HAMD)score(CHD with MDD(HAMD score of 210)vs without MDD).Subjective sleep quality,systemic inflammatory response and cell-mediated immune functions were assessed in patients with CHD with(n=50)and without(n=34)MDD using the Pitsburgh Sleep Quality Index(PSQ1),routine blood tests and flow cytometry.The relationships between variables were ascertained using Pearson's product-moment,and linear discriminant analysis was used to explore the discriminative factors between groups.Results Patients with CHD with MDD had significanty poorer sleep quality than those without MDD(Z=-6.864,p<0.001).The Systemic Inflammation Index(SI)and CD4^(+)/CD8^(+)T-cell ratios were higher in patients with CHD with MDD than in those without MDD(Z=-3.249,p=0.001).Patients with CHD with MDD had fewer CD3^(+)CD8^(+) and CD3^(+)T cells(Z=3.422,p=0.001)than those without MDD(t=2.032,p=0.045).Furthermore,patients with CHD with MDD may be diftrentiated from those without MDD using the PSQI,SII and T-cell levels,as these variables correctly classified the depressed and non-depressed groups with an accuracy of 96.4%.Conclusions MDD may be responsible for poor sleep quality,increased cll-mediated immunity and

关键词： sleep patients coronary

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薄壁弹药机械臂的柔性动力学建模与辨识研究

Acta Mechanica Sinica 2024年第1期40卷 226-239页

作者：汤劲松钱林方马佳陈龙淼陈光宋董帅 School of Mechanical Engineering Nanjing University of Science and Technology Nanjing 20094China School of Civil Engineering Changsha University of Science and TechnologyChangsha 410114China

薄壁结构是机械设计中常用的结构形式,其柔性动力学问题一直是工程研究的前沿。针对具有薄壁结构特性的弹药机械臂,发展了一种基于板壳理论的弹药机械臂柔性多体动力学建模方法.我们在浮动参考坐标框架下,得到了Reissner-Mindlin壳结构... 详细信息

薄壁结构是机械设计中常用的结构形式,其柔性动力学问题一直是工程研究的前沿。针对具有薄壁结构特性的弹药机械臂,发展了一种基于板壳理论的弹药机械臂柔性多体动力学建模方法.我们在浮动参考坐标框架下,得到了Reissner-Mindlin壳结构的运动学方程,其中结构膜变形和弯曲变形与刚性运动的耦合,这是区别于实体结构的特点。为了克服壳体单元模拟中的膜锁定和剪切锁定问题,引入一种基于边中心的应变平滑DSG(ECSS-DSG)单元对结构离散.该方法可以获得更好的膜变形和弯曲变形行为,并且有效克服剪切自锁问题,在结构模态分析中表现出更好的效果.在此基础上,结合实验对弹药机械臂模型参数进行了辨识,并且对辨识模型在各种工况下的动态响应进行了验证,证明了本文方法具有良好的鲁棒性.本文的工作不仅可以为弹药机械臂的进一步研究提供理论支撑,而且可以为薄壁结构多体系统的动力学研究提供参考.

关键词：机械臂实体结构柔性动力学柔性多体动力学薄壁结构多体系统板壳理论弯曲变形