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Egg recognition and nestling discrimination in the Crested Myna(Acridotheres cristatellus):Size matters

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Avian Research 2023年第3期14卷 492-498页

作者： jinmei liu Fangfang Zhang Yuran liu Wei Liang Ministry of Education Key Laboratory for Ecology of Tropical Islands Key Laboratory of Tropical Animal and Plant Ecology of Hainan ProvinceCollege of Life SciencesHainan Normal UniversityHaikou571158China

Most studies exploring abilities of hosts to detect brood parasitism are based on detecting colour and/or pattern differences among parasitic and host eggs or nestlings,while only few were focused on size *** recognition and recognition by discordancy are used to explain cognitive mechanisms of host egg recognition;however,only a few studies have found that hosts use recognition by *** study investigated:1)whether egg and nestling recognitions in the Crested Myna(Acridotheres cristatellus) are based on size cues;2)whether the egg cognitive mechanism is recognition by discordancy based on size cues;and 3) whether the longer the experiment time,the higher the egg recognition *** results showed that the Crested Myna uses egg or nestling size as a recognition cue while the egg and nestling colour and patterning are not associated with egg or nestling rejection,thus the cognitive mechanism of egg recognition in the Crested Myna is recognition by discordancy based on egg size ***,there is a rejection delay in time of egg rejection behaviour of the Crested ***,we suggest that the periodicity of egg rejection experiments could be appropriately extended,especially for species with relatively low egg recognition ability.

关键词： Discordancy recognition Egg rejection Nest sanitation behaviour Nestling discrimination Rejection delay

A Fully Self-Healing Piezoelectric Nanogenerator for Self-Powered Pressure Sensing Electronic Skin

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Research 2021年第1期2021卷 876-884页

作者： Maosen Yang jinmei liu Dong liu Jingyi Jiao Nuanyang Cui Shuhai liu Qi Xu Long Gu Yong Qin School of Advanced Materials and Nanotechnology Xidian UniversityXi’an 710071China Institute of Nanoscience and Nanotechnology Lanzhou UniversityGansu 730000China

As an important way of converting mechanical energy into electric energy,a piezoelectric nanogenerator(PENG)has been widely applied in energy harvesting as well as self-powered sensors in recent ***,its robustness and durability are still severely challenged by frequent and inevitable mechanical impacts in real application ***,a fully selfhealing PENG(FS-PENG)as a self-powered pressure sensing electronic skin is *** self-healing piezoelectric composite and self-healing Ag NW electrode fabricated through mixing piezoelectric PZT particles and conductive Ag NWs into self-healing polydimethylsiloxane(H-PDMS)are assembled into the sandwich structure *** FS-PENG could not only effectively convert external stimulation into electrical signals with a linear response to the pressure but also retain the excellent self-healing and stable sensing property after multiple cycles of cutting and self-healing ***,a self-healing pressure sensor array composed of 9 FS-PENGs was attached on the back of the human hand to mimic the human skin,and accurate monitoring of the spatial position distribution and magnitude of the pressure was successfully realized.

关键词： piezoelectric healing generator

Fabric-Based Triboelectric Nanogenerators

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Research 2019年第1期2019卷 123-135页

作者： jinmei liu Long Gu Nuanyang Cui Qi Xu Yong Qin Rusen Yang School of Advanced Materials and Nanotechnology Xidian UniversityXi’an 710071China Institute of Nanoscience and Nanotechnology Lanzhou UniversityLanzhou 730000China

In the past decades,the progress of wearable and portable electronics is quite rapid,but the power supply has been a great challenge for their practical *** power sources,especially wearable energy-harvesting devices,provide some possible solutions for this *** various wearable energy harvesters,the high-performance fabric-based triboelectric nanogenerators(TENGs)are particularly *** this review paper,we first introduce the fundamentals of TENGs and their four basic working ***,we will discuss the material synthesis,device design,and fabrication of fabric-based ***,we try to give some problems that need to be solved for the further development of TENGs.

关键词： synthesis wear harvesting

Full-length transcriptome sequence and SSR marker development for genetic diversity research in yellowfin seabream Acanthopagrus latus

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Journal of Oceanology and Limnology 2023年第3期41卷 1073-1083页

作者： Jin ZHANG jinmei liu Chong HAN Cheng PENG Yong LI Junhong XIA Yong ZHANG Shuisheng LI Haoran LIN State Key Laboratory of Biocontrol Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic AnimalsSchool of Life SciencesSun Yat-Sen UniversityGuangzhou 510275China Zhuhai Modern Agriculture Development Center Zhuhai 519000China Guangdong Key Laboratory of Animal Conservation and Resource Utilization Guangdong Public Laboratory of Wild Animal Conservation and UtilizationInstitute of ZoologyGuangdong Academy of SciencesGuangzhou 510260China

Yellowfin seabream Acanthopagrus latus is an important economic fish in Chinese coastal *** its narrow distribution and overfishing,the genetic diversity of yellowfin seabream has been restricted for artificial breeding and *** performed full-length transcriptome sequencing and assembly of the genome of yellowfin seabream.A total of 68086 unigenes were obtained,with an N50 of 3391 bp on average length of 2933 bp.A total number of 50593 expressed sequence tags linked to simple sequence repeats(EST-SSR)were identified,among them dinucleotide repeats(40.6%)and AC/GT motifs(38.5%)were the most *** the 190 EST-SSRs for which PCR primer pairs were designed,150 primer pairs successfully amplified target loci and 15 SSRs showed high *** alleles per locus ranged 6-50 on average of *** expected and observed heterozygosity varied from 0.632 to 0.969 and from 0.519 to 0.953,*** polymorphic index content(PIC)values of each locus ranged 0.587-0.966 on average of *** six yellowfin seabream population samples preliminarily tested for genetic diversity and differentiation,the Fangchenggang(FCG)population in Guangxi Province had the highest mean observed heterozygosity(H_(o))value(0.786),whereas the Zhangzhou(ZZ)population in Fujian Province had the lowest(0.678).The pairwise fixation index(Fst)values indicated significant population differentiation among six yellowfin seabream *** study provided evidence for the usefulness of the transcriptomic resource information and EST-SSR markers for natural resource conservation,population genetics,and breeding studies of yellowfin seabream in South China.

关键词： yellowfin seabream Acanthopagrus latus full-length transcriptome expressed sequence tags linked to simple sequence repeats(EST-SSR)marker genetic diversity

Antitumor activity of aumolertinib, a third-generation EGFR tyrosine kinase inhibitor, in non-small-cell lung cancer harboring uncommon EGFR mutations

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Acta Pharmaceutica Sinica B 2023年第6期13卷 2613-2627页

作者： Chen Shi Cong Zhang Zhiwen Fu jinmei liu Yuanfeng Zhou Bao Cheng Cong Wang Shijun Li Yu Zhang Department of Pharmacy Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Hubei Province Clinical Research Center for Precision Medicine for Critical Illness Wuhan 430022China Department of Preclinical Translational Science Shanghai Hansoh Biomedical Co.Ltd.Shanghai 201203China Department of Chemistry Shanghai Hansoh Biomedical Co.Ltd.Shanghai 201203China

Uncommon epidermal growth factor receptor(EGFR) mutations account for 10% 20% of all EGFR mutations in non-small-cell lung cancer(NSCLC). The uncommon EGFR-mutated NSCLC is associated with poor clinical outcomes and generally achieved unsatisfactory effects to the current therapies using standard EGFR-tyrosine kinase inhibitors(TKIs), including afatinib and osimertinib. Therefore, it is necessary to develop more novel EGFR-TKIs to treat uncommon EGFR-mutated *** is a third-generation EGFR-TKI approved in China for treating advanced NSCLC with common EGFR mutations. However, it remains unclear whether aumolertinib is effective in uncommon EGFR-mutated NSCLC. In this work, the in vitro anticancer activity of aumolertinib was investigated in engineered Ba/F3 cells and patient-derived cells bearing diverse uncommon EGFR mutations. Aumolertinib was shown to be more potent in inhibiting the viability of various uncommon EGFR-mutated cell lines than those with wild-type EGFR. And in vivo, aumolertinib could also significantly inhibit tumor growth in two mouse allograft models(V769-D770insASV and L861Q mutations) and a patientderived xenografts model(H773-V774insNPH mutation). Importantly, aumolertinib exerts responses against tumors in advanced NSCLC patients with uncommon EGFR mutations. These results suggest that aumolertinib has the potential as a promising therapeutic candidate for the treatment of uncommon EGFR-mutated NSCLC.

关键词： Aumolertinib Non-small cell lung cancer Oncology Uncommon EGFR mutations Exon 20 insertion EGFR tyrosine kinase inhibitor Targeted therapy Anti-tumor activity

Design of All-aluminum Frame Golf Cart

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International Journal of Plant Engineering and Management 2018年第2期23卷 122-128页

作者： liu jinmei LI Min Greenman Machinery Company Beijing 101301 China

Through the analysis of field situation, combined with the design principle of golf cart and parameters of a cart at home and abroad, the overall plan and the high-strength aluminum truss performance as a vehicle frame are determined. Through the unique look and braking system integrated with brake and parking, finally a novel upscale golf cart is developed

关键词： golf cart all-aluminum alloy frame integrated braking system novel appearance

The genomic and bulked segregant analysis of Curcuma alismatifolia revealed its diverse bract pigmentation

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aBIOTECH 2022年第3期3卷 178-196页

作者： Xuezhu Liao Yuanjun Ye Xiaoni Zhang Dan Peng Mengmeng Hou Gaofei Fu Jianjun Tan Jianli Zhao Rihong Jiang Yechun Xu jinmei liu Jinliang Yang Wusheng liu Luke RTembrock Genfa Zhu Zhiqiang Wu Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen518120China Guangdong Provincial Key Lab of Ornamental Plant Germplasm Innovation and Utilization Environmental Horticulture Research InstituteGuangdong Academy of Agricultural SciencesGuangzhou510640China Yunnan Key Laboratory of Plant Reproductive Adaptation and Evolutionary Ecology Yunnan UniversityKunming650504China Guangxi Engineering and Technology Research Center for Woody Spices Guangxi Key Laboratory for Cultivation and Utilization of Special Non-Timber Forest CropsGuangxi Forestry Research InstituteNanning530002China Department of Agronomy and Horticulture University of Nebraska-LincolnLincolnNE68583USA Department of Horticultural Science North Carolina State UniversityRaleighNC27607USA Department of Agricultural Biology Colorado State UniversityFort CollinsCO80523USA Kunpeng Institute of Modern Agriculture at Foshan Foshan528200China

Compared with most flowers where the showy part comprises specialized leaves(petals)directly subtending the reproductive structures,most Zingiberaceae species produce showy“flowers”through modifications of leaves(bracts)subtending the true flowers throughout an *** alismatifolia,belonging to the Zingiberaceae family,a plant species originating from Southeast Asia,has become increasingly popular in the flower market worldwide because of its varied and esthetically pleasing bracts produced in different ***,we present the chromosome-scale genome assembly of ***“Chiang Mai Pink”and explore the underlying mechanisms of bract *** genomic analysis revealed *** contains a residual signal of whole-genome *** genes,including pigment-related genes,exhibit functional and structural differentiation resulting in diverse bract colors among *** *** addition,we identified the key genes that produce different colored bracts in ***,such as F3′5'H,DFR,ANS and several transcription factors for anthocyanin synthesis,as well as chlH and CAO in the chlorophyll synthesis pathway by conducting transcriptomic analysis,bulked segregant analysis using both DNA and RNA data,and population genomic *** work provides data for understanding the mechanism of bract pigmentation and will accelerate breeding in developing novel cultivars with richly colored bracts in *** and related *** is also important to understand the variation in the evolution of the Zingiberaceae family.

关键词： Anthocyanin synthesis Siam tulip Floriculture Zingiberaceae Genome evolution

EFFECT OF COARSENING OF SURFACE BED MATERIAL ONNON-EQUILIBRIUM SEDIMENT TRANSPORT PROCESSDURING RIVER DEGRADATION

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International Journal of Sediment Research 1999年第2期14卷 275-284页

作者： liu jinmei WANG Guangqian WANG Shiqiang (1,2,3 Dept. of hydraulic Eng., Tsinghua University, Beijing 100084, China)

Previous investigations of non-equilibrium and equilibrium sediment transport are analyzed and a two dimensional (longitudinal profile) mathematical model of non-equilibrium sediment transport in river channels with non-uniform bed material is presented in this paper The concept of exchange rate of bed material is introduced, and a very short time step is used in the calculation. The distance for sediment recovering equilibrium for the non-uniform bed material is far longer than that for uniform bed material and the mechanism of the phenomenon is discussed. Because the size of bed material is coarsened, the scouring of sand is far less than that for the initial state and the distance of non-equilibrium sediment transport becomes much longer. A slower exchange rate of bed material then leads to a longer distance of non-equilibrium sediment transport.

关键词： Coarsening of surface bed material Non-equilibrium sediment transport Exchange rate of bed material Recovering equilibrium distance

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食品生产企业质量信用评价体系设计

食品工业 2020年第11期41卷 253-257页

作者：刘金梅长春工程学院长春130012

我国食品企业诚信意识和安全食品不足、契约精神缺失,加之缺乏有效外部监管,食品质量问题凸显。现行食品生产企业产品质量信用评价机制缺乏具体可行措施,监管主体功能发挥不足,导致评价无依据、评价无后续制约、评价无震慑力等问题突出... 详细信息

我国食品企业诚信意识和安全食品不足、契约精神缺失,加之缺乏有效外部监管,食品质量问题凸显。现行食品生产企业产品质量信用评价机制缺乏具体可行措施,监管主体功能发挥不足,导致评价无依据、评价无后续制约、评价无震慑力等问题突出。构建以有效性、可操作性和灵活性为基本原则的企业质量信用评价体系,完善市场化和行政化信用评价机制建设,建立起包括机构监管、社会监督和惩戒机制协同推进的评价体系,能够有效解决食品生产企业质量安全问题,推动我国食品工业健康发展。

关键词：食品企业质量信用评价食品安全监管