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Chinese Journal of Chemistry 2024年第4期42卷 363-369页

作者： Bin li Mengmeng Xie jingyu li Nana Shen Xinying Zhang Xuesen Fan State Key Laboratory of Antiviral Drugs Pingyuan LaboratoryKey Laboratory of Green Chemical Media and ReactionsKey Laboratory for Yellow River and Huai River Water Environmental Pollution ControlMinistry of EducationSchool of EnvironmentSchool of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiangHenan453007 China

Herein,we report a condition-controlled divergent synthesis of spiro indene-2,1'-isoindolinones and spiro isochroman-3,1'-isoindolinones through cobalt-catalyzed formal[4+1]and[4+1+1]spirocyclization of aromatic amides with 2-diazo-1H-indene-1,3(2H)-*** the reaction is carried out under air in ethyl acetate,spiro indene-2,1'-isoindolinones are formed through Co(II)-catalyzed C—H/N—H[4+1]*** the reaction is run under O2 in CH3CN,on the other hand,spiro isochroman-3,1'-isoindolinones are generated through Baeyer-Villiger oxidation of the in situ formed spiro indene-2,1'-isoindolinones with O2 as a cheaper and environmental-friendly oxygen *** general,these protocols have advantages such as using non-precious and earth-abundant metal catalyst,no extra additive,high efficiency and regioselectivity.A gram-scale synthesis and the removal of the directing group further highlight its utility.

关键词： Spiro indene-2,1'-isoindolinones Spiro isochroman-3,1'-isoindolinones 3d Transition metals Cobalt-catalyzed C-H Activation Switchable[4+1]and[4+1+1]spirocyclization Aromatic amides 2-Diazo-1H-indene-1,3(2H)-dione

Tunable magneto-Seebeck effect in Co_(2)FeSi/MgO/Co_(2)FeSi heterostructure via optimized interfacial engineering

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 128-135页

作者： jingyu li Xianbiao Shi Yurong Jin Le Ma liuming Wei Chi Zhang Hang li Peng-Fei liu International Joint Research Laboratory of New Energy Materials and Devices of Henan Province School of Physics and ElectronicsHenan UniversityKaifeng 475004China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Defence Industry Secrecy Examination and Certification Center Beijing 100089China School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Department of Network Security Henan Police CollegeZhengzhou 450046China College of Electrical Engineering Henan University of TechnologyZhengzhou 450001China

Enhancing the tunneling magneto-Seebeck(TMS) ratio and uncovering its underlying mechanism are greatly demanded in spin *** magnitude and sign of the TMS effect depend on the type of atom and the stacking order of atoms at the ***,we demonstrate that TMS ratios can be effectively manipulated by altering heterogonous or homogeneous interface through decoration on the CoFeSi(001) surface inserted on the MgO insulating *** maximum TMS ratio of pure Co_(2)/O termination is 4565% at 800 ***,the TMS ratio of the FeSi/O termination has two peak values,of which the maximum could reach up to-3290% at 650 *** comparing two different atom arrangements at the interface,we reveal that the sign and symbol of the TMS ratio can be controlled by the temperature and different atomic configurations at the Co_(2)FeSi/MgO ***,the spin-Seebeck coefficient up to ~150 μV/K is also possible when we select suitable terminations and *** findings will provide useful insights into how to control the sign and symbol of the TMS ratio and accordingly stimulate the development field of magneto-thermoelectric power and spin caloritronic devices based on the magneto-Seebeck effect in Heusler-based metallic multilayers.

关键词： magneto-Seebeck effect interface spintronics electronic structure spin-Seebeck effect

Optimal Operation Strategy of Electricity-Hydrogen Regional Energy System under Carbon-Electricity Market Trading

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Energy Engineering 2024年第3期121卷 619-641页

作者： jingyu li Mushui Wang Zhaoyuan Wu Guizhen Tian Na Zhang Guangchen liu Inner Mongolia Key Laboratory of Electrical Energy Conversion Transmission and Control Inner Mongolia University of TechnologyHohhot010080China School of Electric Power Inner Mongolia University of TechnologyHohhot010080China School of Electrical and Electronic Engineering North China Electric Power UniversityBeijing102206China

Given the“double carbon”objective and the drive toward low-carbon power,investigating the integration and interaction within the carbon-electricity market can enhance renewable energy utilization and facilitate energy conservation and emission reduction ***,further research is necessary to explore operational optimization methods for establishing a regional energy system using Power-to-Hydrogen(P2H)technology,focusing on participating in combined carbon-electricity market *** study introduces an innovative Electro-Hydrogen Regional Energy System(EHRES)in this *** system integrates renewable energy sources,a P2H system,cogeneration units,and energy storage *** core purpose of this integration is to optimize renewable energy utilization and minimize carbon *** study aims to formulate an optimal operational strategy for EHRES,enabling its dynamic engagement in carbon-electricity market *** initial phase entails establishing the technological framework of the electricity-hydrogen coupling system integrated with ***,an analysis is conducted to examine the operational mode of EHRES as it participates in carbon-electricity market ***,the system scheduling model includes a stepped carbon trading price mechanism,considering the combined heat and power generation characteristics of the Hydrogen Fuel Cell(HFC).This facilitates the establishment of an optimal operational model for EHRES,aiming to minimize the overall operating *** simulation example illustrates that the coordinated operation of EHRES in carbon-electricity market transactions holds the potential to improve renewable energy utilization and reduce the overall system *** result carries significant implications for attaining advantages in both low-carbon and economic aspects.

关键词： Regional energy system electro-hydrogen coupling carbon-electricity market step carbon trading coordination and optimization

Lactate regulates major zygotic genome activation by H3K18 lactylation in mammals

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National Science Review 2024年第2期11卷 124-134页

作者： jingyu li Weibo Hou Qi Zhao Wei Han Hongdi Cui Songling Xiao ling Zhu Jiadan Qu Xiaoyu liu Weitao Cong Jingling Shen Yuzheng Zhao Shaorong Gao Guoning Huang Qingran Kong Chongqing Key Laboratory of Human Embryo Engineering Center for Reproductive Medicine Chongqing Health Center for Women and ChildrenWomen and Children's Hospital of Chongqing Medical University Oujiang Laboratory Zhejiang Provincial Key Laboratory of Medical Genetics Key Laboratory of Laboratory MedicineMinistry of EducationSchool of Laboratory Medicine and Life Sciences Wenzhou Medical University Frontier Science Center for Stem Cell Research School of Life Sciences and Technology Tongji University School of Pharmaceutical Science Wenzhou Medical University Institute of life Sciences College of Life and Environmental Sciences Wenzhou University Optogenetics&Synthetic Biology Interdisciplinary Research Center State Key Laboratory of Bioreactor Engineering Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism School of Pharmacy East China University of Science and Technology

Lactate is present at a high level in the microenvironment of mammalian preimplantation embryos in vivo and in vitro. However, its role in preimplantation development is unclear. Here, we report that lactate is highly enriched in the nuclei of early embryos when major zygotic genome activation(ZGA) occurs in humans and mice. The inhibition of its production and uptake results in developmental arrest at the 2-cell stage, major ZGA failure, and loss of lactate-derived H3K18lac, which could be rescued by the addition of Lac-Co A and recapitulated by overexpression of H3K18R mutation. By profiling the landscape of H3K18lac during mouse preimplantation development, we show that H3K18lac is enriched on the promoter regions of most major ZGA genes and correlates with their expressions. In humans, H3K18lac is also enriched in ZGA markers and temporally concomitant with their expressions. Taken together, we profile the landscapes of H3K18lac in mouse and human preimplantation embryos, and demonstrate the important role for H3K18lac in major ZGA, showing that a conserved metabolic mechanism underlies preimplantation development of mammalian embryos.

关键词： mammalian preimplantation development lactate epigenetic remodeling histone lactylation zygotic genome activation

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仪戏交融:探闽浙夫人戏的源流与形成

世界宗教文化 2024年第1期 181-188页

作者：李菁钰福建师范大学音乐学院

夫人戏源于临水夫人陈靖姑信仰,是民间表演陈靖姑题材之戏曲艺术的泛称。夫人戏拥有深厚的陈靖姑信俗文化背景,民间传说与民间说唱作为夫人戏同源同流的亲缘血脉共同促进民间艺术的衍化,传奇小说对夫人戏的情节架构起到了规范与统一的作... 详细信息

夫人戏源于临水夫人陈靖姑信仰,是民间表演陈靖姑题材之戏曲艺术的泛称。夫人戏拥有深厚的陈靖姑信俗文化背景,民间传说与民间说唱作为夫人戏同源同流的亲缘血脉共同促进民间艺术的衍化,传奇小说对夫人戏的情节架构起到了规范与统一的作用,而傀儡戏从“十八罗汉”到“三十六天罡”规制的三种递变,使夫人戏具备了独特的祭仪式特质,最终形成了融信仰、艺术于一体的民间祭祀仪式戏剧。

关键词：夫人戏陈靖姑傀儡戏仪式戏剧

以数实融合推动新型工业化的阶段性特征、战略定位与路径选择

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经济与管理评论 2024年第2期40卷 5-16页

作者：任保平李婧瑜南京大学数字经济与管理学院江苏苏州215163 西北大学经济管理学院陕西西安710127

新型工业化是我国高质量发展在工业化发展战略中的集中体现。在高质量发展阶段我国新型工业化发展的环境条件发生了深刻变化,既有数字经济背景下数字技术更迭带来的诸多新机遇和新挑战,也有国际分工结构调整与全球竞争加剧和国内过去工... 详细信息

新型工业化是我国高质量发展在工业化发展战略中的集中体现。在高质量发展阶段我国新型工业化发展的环境条件发生了深刻变化,既有数字经济背景下数字技术更迭带来的诸多新机遇和新挑战,也有国际分工结构调整与全球竞争加剧和国内过去工业发展模式的弊病逐渐显现。以数实融合推动新型工业化具有创新驱动、“四化”互通、高效集约、内外联动、供需协同的阶段性特征。以数实融合推动新型工业化,在目标要求定位上,要稳步迈进数字制造强国行列、筑牢新型工业化物质根基、营造利于新型工业化发展的外部环境;在主要内容定位上,要以质量变革、效率变革、动力变革持续推进我国新型工业化进程。因此,以数实融合推动新型工业化在实现路径上要着力提升产业链供应链韧性和安全水平,加快提升产业创新能力和人才综合素质,持续推动工业结构优化升级和工业企业“智改数转”,大力推动数字技术与实体经济深度融合。

关键词：数字经济实体经济新型工业化高质量发展

面向人机共驾模式下驾驶人接管过程的视觉转移特性研究

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汽车工程 2024年第5期46卷 795-804页

作者：李梦凡冯忠祥张卫华李靖宇合肥工业大学土木与水利工程学院合肥230000 合肥工业大学汽车与交通工程学院合肥230000

当在L3级自动驾驶系统操作期间,驾驶人无须时刻监管车辆,往往会处于脱离驾驶任务的状态,并可能从事各种与驾驶无关的任务。当自动驾驶系统遇到突发状况并发出接管请求时,驾驶人是否能安全及时地进行人机交互操作并顺利接管车辆是目前L3... 详细信息

当在L3级自动驾驶系统操作期间,驾驶人无须时刻监管车辆,往往会处于脱离驾驶任务的状态,并可能从事各种与驾驶无关的任务。当自动驾驶系统遇到突发状况并发出接管请求时,驾驶人是否能安全及时地进行人机交互操作并顺利接管车辆是目前L3级自动驾驶所面临的重要问题。本文针对驾驶人接管操作过程,根据道路线形的差异性,设计了5种不同道路场景进行L3级自动驾驶接管试验,分析了驾驶人在不同道路场景下的注视熵,构建了驾驶人接管行为的马尔可夫链注视模型,探讨了自动驾驶人机交互过程中驾驶人的视觉转移特性。结果表明,驾驶人在接管操作期间表现出明显的注视行为规律,重点关注道路前方、次任务区域和人机交互区域。随着道路曲率半径的减小,驾驶人的视觉特性呈现出明显的变化,对道路前方和右侧区域的关注增加,而对次任务区域的关注减少。结果可为自动驾驶人机界面的优化研究提供科学依据,从而提高驾驶员接管绩效和驾驶安全。

关键词：自动驾驶人机交互人机接管注视特性马尔可夫链

基于随机森林融合的金融机构风险关联影响因素研究

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系统工程理论与实践 2024年第1期44卷 296-315页

作者：李靖宇郭湘媛谢启伟郑晓龙北京工业大学经济与管理学院北京100124 中国科学院自动化研究所北京100190 中国科学院大学人工智能学院北京101408

“太关联而不能倒”使得金融机构风险关联及其影响因素成为维护金融稳定的重要问题.本文借鉴随机森林进行基因调控研究的思想,将森林融合和随机置换相结合,提出构建变量间关联网络的方法,探究金融机构风险关联及相关因素的影响关系.所... 详细信息

“太关联而不能倒”使得金融机构风险关联及其影响因素成为维护金融稳定的重要问题.本文借鉴随机森林进行基因调控研究的思想,将森林融合和随机置换相结合,提出构建变量间关联网络的方法,探究金融机构风险关联及相关因素的影响关系.所提出的方法能克服传统回归分析、格兰杰因果检验和贝叶斯网络等方法的不足,随机置换的引入提升了模型对变量异质性的解决能力.基于2012–2022年46家中国上市金融机构的实证结果表明,所构建的网络能够清晰识别不同因素对风险关联的直接或间接影响作用,并且揭示了因素的影响路径,从而提供更为系统全面的影响关系刻画结果,表明本文方法在解决该问题上具有适用性,可以为金融监管和风险管理提供有力工具.

关键词：金融机构风险关联随机森林随机置换

大气污染对抑郁症的影响及其潜在作用机制的研究进展

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环境与职业医学 2024年第4期41卷 457-465页

作者：李靖宇杨文慧徐燕意复旦大学公共卫生学院环境卫生学教研室上海200032

大气污染是威胁人类健康的全球性问题。近年来,越来越多的研究发现,大气污染与抑郁症的发生密切相关。抑郁症是一种严重的神经精神疾病,其发病率逐年攀升,已成为威胁人类健康的隐形杀手。目前,大气污染与抑郁症的相关性研究仍十分有限,... 详细信息

大气污染是威胁人类健康的全球性问题。近年来,越来越多的研究发现,大气污染与抑郁症的发生密切相关。抑郁症是一种严重的神经精神疾病,其发病率逐年攀升,已成为威胁人类健康的隐形杀手。目前,大气污染与抑郁症的相关性研究仍十分有限,大气污染影响抑郁发生的分子机制也尚不明确。本文基于国内外现有的流行病学和毒理学研究,针对大气污染与抑郁症的关系及其可能的生物学机制进行综述,重点阐述了大气污染与抑郁结局指标之间的关系以及大气污染物种类、暴露时间、研究对象的年龄及健康状况等影响抑郁的可能因素,并总结归纳了神经炎症、氧化应激、神经发生、细胞凋亡等机制在空气污染导致抑郁过程中可能发挥的潜在作用,以期为大气污染的防控与抑郁症的预防和治疗提供科学依据。

关键词：大气污染细颗粒物抑郁症分子机制

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水分对木材细胞壁孔隙结构影响研究进展

北京林业大学学报 2024年第2期46卷 1-8页

作者：马尔妮王瑜瑶李京予仲翔北京林业大学木材科学与工程北京市重点实验室北京100083

木材是一种具有多级孔隙结构的天然可再生资源,其孔隙构造尤其是细胞壁孔隙结构至关重要。细胞壁孔隙结构的研究是木材加工的理论基础,对于提高木材综合利用率具有重要的现实意义。本文简要介绍了木材孔隙的种类及其表征技术,在此基础... 详细信息

木材是一种具有多级孔隙结构的天然可再生资源,其孔隙构造尤其是细胞壁孔隙结构至关重要。细胞壁孔隙结构的研究是木材加工的理论基础,对于提高木材综合利用率具有重要的现实意义。本文简要介绍了木材孔隙的种类及其表征技术,在此基础上梳理了水分对木材细胞壁孔隙结构影响的相关研究成果,总结了目前由水分引发的木材细胞壁孔隙结构变化领域仍存在的一些问题与挑战,对未来的发展方向及其前景进行展望,以期为深入揭示木材与水分的相互作用提供参考。

关键词：木材孔隙细胞壁木材水分孔隙结构孔隙表征