检索结果-南通市图书馆

Water-Excluding Underwater Glue Induced by Marangoni Effect

在线全文

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第5期6卷 1289-1299页

作者： Ke Zhang Xizi Wan Zi-Yu Liu Feilong Zhang jingwei lu Jingxin Meng Ye Tian Haeshin Lee Lei Jiang Shutao Wang CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190 Green Catalysis Center College of ChemistryZhengzhou UniversityZhengzhou 450001 University of Chinese Academy of Sciences Beijing 100049 Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190 Beijing Key Laboratory for Bioengineering and Sensing Technology School of Chemistry and Biological EngineeringUniversity of Science and Technology BeijingBeijing 100083 The Graduate School of Nanoscience and Technology Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141

Marangoni effect at the two-phase interface with different surface tension as a unique mass transfer phenomenon has been widely used in daily life and ***,their marvelous liquid-driving capability between miscible liquids has long been ignored,especially in water ***,we first reveal a distinct underwater Marangoni effect between the solvent of glues and the water layer on solid *** by the Marangoni effect,organic solvents with water solubility,high dielectric constant,and low diffusivity could effectively exclude the interfacial water layer,enabling direct and effective contact between glues and solid *** experimental results and theoretical simulation proved that a relatively large ratio of the Marangoni number in the horizontal direction and to the vertical direction ensured an effective underwater adhesion of the water-excluding *** surface engineering approach provides an alternative to the traditional methods of molecular engineering for realizing underwater adhesion.

关键词： Marangoni effect underwater adhesion dynamic water-excluding water layer solvent diffusion

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

影响肌腱干细胞分化的因素

中国组织工程研究 2024年第13期28卷 2098-2104页

作者：逯静薇吕可馨蒋莉陈艺萱石厚银李森西南医科大学体育学院四川省泸州市646000 西南医科大学附属中医医院四川省泸州市646000

背景:肌腱病是一种肌肉骨骼疾病,以疼痛和活动能力下降为特征,伴有胶原蛋白紊乱和血管增生的病理变化。肌腱病常易发生在运动员、体力劳动者和老年人身上。肌腱病的机制之一是“失败的愈合反应”,而导致失败愈合反应的部分原因是肌腱干... 详细信息

背景:肌腱病是一种肌肉骨骼疾病,以疼痛和活动能力下降为特征,伴有胶原蛋白紊乱和血管增生的病理变化。肌腱病常易发生在运动员、体力劳动者和老年人身上。肌腱病的机制之一是“失败的愈合反应”,而导致失败愈合反应的部分原因是肌腱干细胞的错误分化。目的:通过阅读相关文献,介绍肌腱干细胞的特性,总结影响肌腱干细胞向肌腱细胞分化的因素以及导致肌腱干细胞错误分化(分化为脂肪细胞、骨细胞和软骨细胞)的因素,同时阐述肌腱干细胞在临床中的应用局限。方法:检索PubMed及Web of Science数据库中相关文献,检索词为“Tendon Stem/Progenitor Cells,Tendinopathy,Tendon injury,differentiation”,通过阅读筛选出相关文献,最终纳入109篇文献进行结果分析。结果与结论:①肌腱干细胞是可以自发分化为肌腱的一种干细胞,它具有自我更新、克隆和多向分化的能力,不同的外部条件作用于肌腱干细胞可以导致其向不同方向分化。调节肌腱干细胞命运的具体因素并不确定。当肌腱中的干细胞更新和分化出现异常时,会导致肌腱愈合失败,进而导致肌腱病。②衰老、细胞外基质成分的变化、过度的机械刺激、前列腺素E2和白细胞介素6以及白细胞介素10和一些系统性疾病可能对调控肌腱干细胞的错误分化有重要意义。③促进肌腱干细胞向腱细胞分化的可能有利因素有:一些生长因子和细胞因子、适度的机械刺激和细胞外基质的地形、低氧张力、药物以及某些转录基因和蛋白。④目前最为理想的治疗手段则是对内源性肌腱干细胞进行调节,或者外源性肌腱干细胞刺激内源性肌腱干细胞的增殖分化。⑤未来研究进一步了解调节肌腱干细胞错误分化的因素,可深入了解肌腱病的发病机制并找到治疗靶点,阐述诱导肌腱干细胞向肌腱分化则可促进其在组织工程中的应用。

关键词：肌腱干细胞干细胞肌腱病肌腱损伤肌腱愈合肌腱干细胞分化生长因子组织工程影响因素综述

Parallel Factories for Smart Industrial Operations:From Big AI Models to Field Foundational Models and Scenarios Engineering

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2022年第12期9卷 2079-2086页

作者： jingwei lu Xingxia Wang Xiang Cheng Jing Yang Oliver Kwan Xiao Wang Qingdao Academy of Intelligent Industries Qingdao 266114 The State Key Laboratory for Management and Control of Complex Systems Chinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100190 Motion G Inc.Singapore 068898Singapore IEEE School of Artificial Intelligence Anhui UniversityHefei 230031

The rapid advancement of fundamental theories and computing capacity has brought artificial intelligence,internet of things, extended reality, and many other new intelligent technologies into our daily lives. Due to the lack of interpretability and reliability guarantees, it is extremely challenging to apply these technologies directly to real-world industrial systems. Here we present a new paradigm for establishing parallel factories in metaverses to accelerate the deployment of intelligent technologies in real-world industrial systems: QAII-1.0. Based on cyber-physical-social systems,QAII-1.0 incorporates complex social and human factors into the design and analysis of industrial operations and is capable of handling industrial operations involving complex social and human behaviors. In QAII-1.0, a field foundational model called Eu Artisan combined with scenarios engineering is developed to improve the intelligence of industrial systems while ensuring industrial interpretability and reliability. Finally, parallel oil fields in metaverses are established to demonstrate the operating procedure of QAII-1.0.

关键词： Cyber-physical-social system(CPSS) Industry5.0 Metaverses Parallel factories Parallel intelligence

绛红褐链霉菌CC2-6抑制大白菜根肿病的效果及机制分析

在线全文

学校读者我要写书评

暂无评论

园艺学报 2024年第5期51卷 1137-1150页

作者：王青胡燕陈姗陆景伟郑阳陶伟林孙现超周娜陈国康西南大学植物保护学院重庆400716 重庆市农业科学院蔬菜花卉研究所重庆401329 浙江省嘉善县林业技术推广站浙江嘉善314199

为筛选可抑制芸薹根肿菌(Plasm odiophora brassicae)的生防菌株,以棉花枯萎病尖孢镰刀菌(Fusarium oxysporum)为指示菌,通过平板对峙法筛选出优良菌株CC2-6,其抑制率为50.03%;该菌株发酵液能抑制根肿菌休眠孢子萌发及根肿菌根毛侵染,提... 详细信息

为筛选可抑制芸薹根肿菌(Plasm odiophora brassicae)的生防菌株,以棉花枯萎病尖孢镰刀菌(Fusarium oxysporum)为指示菌,通过平板对峙法筛选出优良菌株CC2-6,其抑制率为50.03%;该菌株发酵液能抑制根肿菌休眠孢子萌发及根肿菌根毛侵染,提前7 d接菌CC2-6对大白菜根肿病的盆栽防效为53.20%。同时,该菌株CC2-6对包括烟草叶斑病菌(Pestalotiopsis nicotiae)等9种病原菌均有抑制效果,其抑菌率在47.20%~76.19%,表明菌株CC2-6具有广谱抑菌活性。形态学观察及16S rDNA基因序列分析,初步鉴定菌株CC2-6为绛红褐链霉菌(Streptomyces purpeofuscus)。菌株CC2-6可产生蛋白酶、纤维素酶、几丁质酶,其发酵液可诱导大白菜中的PPO、POD、PAL活性增强,SA、JA含量升高,降低ET含量。GC-TOF/LC-QTOF/QE非靶标代谢组学检测结果表明,菌株CC2-6发酵液中含有潮霉素B(Hygromycin B)、喜树碱(Camptothecin)、2–苯乙醇(2-Phenylethanol)、柠檬酸(Citric acid)等抑菌活性物质,表明CC2-6可能通过产生上述化合物抑制根肿菌侵染寄主。

关键词：根肿菌生防放线菌绛红褐链霉菌诱导抗性代谢产物

氧化铈负载聚己内酯创面敷料在神经外科术后护理中的应用效果研究

在线全文

学校读者我要写书评

暂无评论

黑龙江医学 2024年第4期48卷 473-475页

作者：刘爽郑玉婷陆井伟尹萍张明辉哈尔滨医科大学附属第四医院黑龙江哈尔滨150001

目的:探讨氧化铈负载聚己内酯创面敷料在神经外科开颅患者术后伤口护理中的应用效果,为临床术后护理及降低并发症发生率提供依据。方法:选取2021年2月—2022年12月哈尔滨医科大学附属第四医院收治的124例接受神经外科开颅手术的患者作... 详细信息

目的:探讨氧化铈负载聚己内酯创面敷料在神经外科开颅患者术后伤口护理中的应用效果,为临床术后护理及降低并发症发生率提供依据。方法:选取2021年2月—2022年12月哈尔滨医科大学附属第四医院收治的124例接受神经外科开颅手术的患者作为研究对象,根据住院号的奇偶数将其分为对照组和实验组,每组各62例。对照组患者的手术伤口采用传统外科敷料进行覆盖,实验组患者使用氧化铈负载聚己内酯敷料进行覆盖,比较两组患者伤口无菌拭子培养阳性率、伤口愈合比值、伤口换药平均出血量和不良反应发生情况。结果:实验组患者术后第2天、第4天、第6天的伤口无菌拭子培养阳性率明显低于对照组,差异有统计学意义(χ^(2)=4.888、4.593、5.962,P<0.05)。术后当天、第2天、第4天、第6天,实验组患者的伤口愈合比值明显低于对照组,差异有统计学意义(χ^(2)=-2.813、2.552、2.544、5.555,P<0.05)。实验组患者伤口换药平均出血量明显低于对照组,差异有统计学意义(t=2.555,P<0.05)。实验组患者不良反应发生率明显低于对照组,差异有统计学意义(χ^(2)=8.798,P<0.05)。结论:在神经外科开颅患者术后的伤口护理中应用氧化铈负载聚己内酯创面敷料,能够降低患者伤口无菌拭子培养阳性率、伤口愈合比值、伤口换药平均出血量及不良反应发生率。

关键词：氧化铈负载聚己内酯创面敷料开颅术后伤口护理临床应用

Parallel Control for Optimal Tracking via Adaptive Dynamic Programming

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2020年第6期7卷 1662-1674页

作者： jingwei lu Qinglai Wei Fei-Yue Wang School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049 The State Key Laboratory for Management and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China IEEE State Key Laboratory for Management and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190 Institute of Systems Engineering Macao University of Science and TechnologyMacao 999078 Qingdao Academy of Intelligent Industries Qingdao 266109China

This paper studies the problem of optimal parallel tracking control for continuous-time general nonlinear *** existing optimal state feedback control,the control input of the optimal parallel control is introduced into the feedback ***,due to the introduction of control input into the feedback system,the optimal state feedback control methods can not be applied *** address this problem,an augmented system and an augmented performance index function are proposed ***,the general nonlinear system is transformed into an affine nonlinear *** difference between the optimal parallel control and the optimal state feedback control is analyzed *** is proven that the optimal parallel control with the augmented performance index function can be seen as the suboptimal state feedback control with the traditional performance index ***,an adaptive dynamic programming(ADP)technique is utilized to implement the optimal parallel tracking control using a critic neural network(NN)to approximate the value function *** stability analysis of the closed-loop system is performed using the Lyapunov theory,and the tracking error and NN weights errors are uniformly ultimately bounded(UUB).Also,the optimal parallel controller guarantees the continuity of the control input under the circumstance that there are finite jump discontinuities in the reference ***,the effectiveness of the developed optimal parallel control method is verified in two cases.

关键词： Adaptive dynamic programming(ADP) nonlinear optimal control parallel controller parallel control theory parallel system tracking control neural network(NN)

A slippery hydrogel coating with durable oil-repellent property and self-regeneration capacity

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2022年第8期65卷 1819-1827页

作者： XU Ting GAO ZhongShuai LI FangChao MIAO Gan JIA YuYu MIAO Xiao ZHU XiaoTao lu jingwei WANG Bo SONG YuanMing REN GuiNa LI XiangMing School of Environmental and Material Engineering Yantai UniversityYantai 264405China Shandong Key Laboratory of Optical Communication Science and Technology School of Physics Science and Information TechnologyLiaocheng UniversityLiaocheng 252000China

Traditional lubricant impregnated surfaces usually required fluorinated lubricants to achieve slippery oil repellency, but the lubricants infused were expensive and toxic and also suffered from limited stability because of their migrating, evaporating, and leaking during use. Herein, to address this issue, we fabricated a durably fluorine-free slippery oil-repellent hydrogel coating using water as the lubricant. Due to its enhanced water-binding affinity, water could wet the hydrogel completely and form a hydrated-water layer on the surface. The hydrated water layer could act as a lubricant to repel foreign oils, which allowed the hydrogel to display slippery oil-repellency in air, exhibit superoleophobicity underwater, and resist oil fouling upon oil *** hydrogel kept its oil-repellent properties after mechanical tests as well as thermal and freezing treatments,demonstrating its durability. Thanks to its moisture absorption, the water lubricant layer could self-regenerate upon the lubricated water layer depletion through exposure to a humid environment. Exploiting it is water-attracting and oil repellency, the hydrogel coating was demonstrated as a versatile platform for oil/water separation, polymer/water separation, drag-reduction, and antifogging.

关键词： slippery oil repellency self-regeneration moisture absorbing oil/water separation

Flexible regulation engineering of titanium nitride nanofibrous membranes for efficient electromagnetic microwave absorption in wide temperature spectrum

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第3期17卷 1666-1675页

作者： Cuiping Li lu Zhang Shuai Zhang Qiqi Yu Dan Li Lei Zhang Chunhong Gong jingwei Zhang Institute of Functional Polymer Composites College of Chemistry and Molecular SciencesHenan UniversityKaifeng 475004China National&Local Joint Engineering Research Center for Applied Technology of Hybrid Nanomaterials Henan UniversityKaifeng 475004China

Simultaneous development of well impedance matching and strong loss capability has become a mainstream method for achieving outstanding electromagnetic microwave absorption(EMWA)performances over wide temperature ***,it is difficult to pursue both due to the mutual restraint of relationship between impedance matching and loss capability about ***,we propose a flexible regulation engineering of titanium nitride(TiN)nanofibrous membranes(NMs,TNMs),which could be distributed uniformly in the polydimethylsiloxane(PDMS)matrix and contributed to the formation of abundant local conductive networks,generating the local conductive loss and enhancing the loss ability of ***,when the TNMs are used as functional units and dispersed in the matrix,the corresponding composites exhibit an outstanding anti-reflection effect on *** hoped,under the precondition of good impedance matching,local conductive loss and polarization loss together improve the loss capacity at room temperature,and polarization loss can compensate the local conductive loss to acquire effective dielectric response at elevated *** from the reasonably synergistic loss ability caused by flexible regulation engineering,the corresponding composites exhibit the perfect EMWA performances in a wide temperature range from 298 to 573 *** work not only elaborates the ponderable insights of independent membrane in the composition-structure-function connection,but also provides a feasible tactic for resolving coexistence of well impedance matching and strong loss capability issues in wide temperature spectrum.

关键词： flexible titanium nitride nanofibrous membranes local conductive loss dielectric loss electromagnetic microwave absorption wide temperature spectrum

Drug repurposing screening and mechanism analysis based on human colorectal cancer organoids

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Protein & Cell 2024年第4期15卷 285-304页

作者： Yunuo Mao Wei Wang jingwei Yang Xin Zhou Yongqu lu Junpeng Gao Xiao Wang lu Wen Wei Fu Fuchou Tang School of Life Sciences Biomedical Pioneering Innovation CenterDepartment of General SurgeryThird HospitalPeking UniversityBeijing 100871China Beijing Advanced Innovation Center for Genomics(ICG) Ministry of Education Key Laboratory of Cell Proliferation and DifferentiationBeijing 100871China Peking-Tsinghua Center for Life Sciences Peking UniversityBeijing 100871China Peking University Third Hospital Cancer Center Beijing 100871China The Research Center of Stem Cell and Regenerative Medicine School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China

Colorectal cancer(CRC)is a highly heterogeneous cancer and exploring novel therapeutic options is a pressing issue that needs to be ***,we established human CRC tumor-derived organoids that well represent both morphological and molecular heterogeneities of original *** efficiently identify repurposed drugs for CRC,we developed a robust organoid-based drug screening *** combining the repurposed drug library and computation-based drug prediction,335 drugs were tested and 34 drugs with anti-CRC effects were *** importantly,we conducted a detailed transcriptome analysis of drug responses and divided the drug response signatures into five representative patterns:differentiation induction,growth inhibition,metabolism inhibition,immune response promotion,and cell cycle *** anticancer activities of drug candidates were further validated in the established patient-derived organoids-based xenograft(PDOX)system in *** found that fedratinib,trametinib,and bortezomib exhibited effective anticancer ***,the concordance and discordance of drug response signatures between organoids in vitro and pairwise PDOX in vivo were *** study offers an innovative approach for drug discovery,and the representative transcriptome features of drug responses provide valuable resources for developing novel clinical treatments for CRC.

关键词： colorectal cancer organoids drug repurposing patient-derived organoids-based xenograft mechanism of action