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中国临床护理 2024年第9期16卷 588-591,F0003页

作者：殷勤丽高敬书牡丹江医学院护理学院黑龙江牡丹江150000 黑龙江中医药大学附属第一医院妇科哈尔滨150040

文章系统回顾了儿童癌症幸存者体力活动的相关研究,对儿童癌症幸存者体力活动的现状、影响因素和干预措施等进行综述,以期为儿童癌症幸存者体力活动的干预研究和护理实践提供参考。

关键词：儿童癌症癌症幸存者体力活动综述

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中医特色疗法治疗分娩疼痛的研究进展

中外女性健康研究 2024年第1期 57-59页

作者：李燕春高敬书牡丹江医学院2021级硕士研究生黑龙江牡丹江157011 黑龙江中医药大学附属第一医院妇科一科黑龙江哈尔滨150040

分娩疼痛是孕妇普遍面临的问题,传统的疼痛管理方式存在副作用和局限性。中医特色疗法具有独特的理论和方法,已经被广泛应用于治疗分娩疼痛。本文旨在综述针灸、穴位按摩、耳穴压豆等中医特色疗法治疗分娩疼痛的研究进展,以期为分娩疼... 详细信息

分娩疼痛是孕妇普遍面临的问题,传统的疼痛管理方式存在副作用和局限性。中医特色疗法具有独特的理论和方法,已经被广泛应用于治疗分娩疼痛。本文旨在综述针灸、穴位按摩、耳穴压豆等中医特色疗法治疗分娩疼痛的研究进展,以期为分娩疼痛的临床治疗提供参考。

关键词：中医特色疗法分娩疼痛综述

非痰湿型多囊卵巢综合征患者高血脂症的影响因素

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中华中医药杂志 2024年第7期39卷 3833-3837页

作者：罗蓉王宇高敬书丛晶葛航刘洋张蓓吴效科黑龙江中医药大学哈尔滨150040 黑龙江中医药大学附属第一医院哈尔滨150040 黑龙江省医院哈尔滨150030 徐州市中心医院徐州221000

目的:探讨非痰湿型多囊卵巢综合征(PCOS)患者的人群特征以及高血脂症的影响因素。方法:选取479例“针刺联合克罗米芬对PCOS不孕妇女活产的影响”临床试验(PCOSAct)非痰湿型受试者为研究对象,分析该类患者的人群特征。再将患者分为血脂正... 详细信息

目的:探讨非痰湿型多囊卵巢综合征(PCOS)患者的人群特征以及高血脂症的影响因素。方法:选取479例“针刺联合克罗米芬对PCOS不孕妇女活产的影响”临床试验(PCOSAct)非痰湿型受试者为研究对象,分析该类患者的人群特征。再将患者分为血脂正常307例和高血脂症172例,分析两组的人口学特征及生化指标。最后分析各指标与血脂成分的相关性及高血脂症的危险或保护性因素。结果:血脂成分以低高密度脂蛋白胆固醇(HDL-c)型为主,20.46%(98/479)患者1种成分异常,14.82%(71/479)患者伴2~3种成分异常。高血脂症年龄、身体质量指数(BMI)、腰围、腰臀比、收缩压、游离雄激素、游离雄激素指数、空腹胰岛素、稳态模型胰岛素抵抗指数、总胆固醇、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-c)、载脂蛋白B、乳酸脱氢酶(LDH)、谷丙转氨酶、谷草转氨酶显著高于血脂正常(P<0.01,P<0.05);而黄体生成素(LH)、LH/卵泡刺激素、性激素结合球蛋白(SHBG)、HDL-c、载脂蛋白A1、总胆红素、直接胆红素(DB)显著低于血脂正常(P<0.01,P<0.05)。TG与肥胖、胰岛素抵抗及肝功能的相关性最强(P<0.01),HDL-c与性激素(尤其SHBG)及LDH的相关性最强(P<0.01)。年龄、BMI、LDH是高血脂症的危险性因素,而SHBG、DB是保护性因素。结论:非痰湿型PCOS患者仍伴有较严重的高血脂症,年龄、BMI、LDH是高血脂症独立的危险性因素,SHBG和DB是保护性因素。

关键词：多囊卵巢综合征非痰湿型高血脂症影响因素生化指标

中国南北方多囊卵巢综合征不孕患者临床基线特征分布与疗效分析

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中华中医药杂志 2024年第4期39卷 2077-2080页

作者：马红丽朱韵怡高敬书王宇沈文娟吴效科黑龙江中医药大学附属第一医院哈尔滨150040 黑龙江中医药大学哈尔滨150040 黑龙江省医院哈尔滨150036

目的:分析我国南北方多囊卵巢综合征(PCOS)不孕患者临床基线特征及疗效的差异,从而为不同地域女性预防与治疗PCOS提供指导。方法:以秦岭-淮河线将644例PCOS患者按就诊医院分为北方和南方,随机给予小檗碱、来曲唑或小檗碱联合来曲唑治疗... 详细信息

目的:分析我国南北方多囊卵巢综合征(PCOS)不孕患者临床基线特征及疗效的差异,从而为不同地域女性预防与治疗PCOS提供指导。方法:以秦岭-淮河线将644例PCOS患者按就诊医院分为北方和南方,随机给予小檗碱、来曲唑或小檗碱联合来曲唑治疗,配合超声监测排卵,疗程共6个月。观察南北方PCOS受试者临床基线特征及疗效的差异。结果:南方P C O S受试者年龄,身高,体质量,腰围,臀围,身体质量指数,左、右卵巢体积,孕酮,促黄体生成素/促卵泡生成素,游离睾酮指数,胰岛素浓度等显著低于北方PCOS受试者(P<0.01);左、右侧窦卵泡数,促卵泡生成素,性激素结合球蛋白水平,抗苗勒管激素显著高于北方PCOS受试者(P<0.05,P<0.01);南北方PCOS受试者的排卵率、受孕率、妊娠率、流产率及活产率差异均无统计学意义。结论:北方受试者的PCOS病情重于南方受试者,地域差异及病情严重程度对促排卵药物疗效及生殖结局没有明显影响。

关键词：多囊卵巢综合征基线特征临床表型特征不同地域身体质量指数

基于中医辨证的克罗米芬治疗多囊卵巢综合征不孕症疗效研究

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中华中医药杂志 2024年第9期39卷 5057-5061页

作者：王宇丛晶高敬书马红丽张蓓曹义娟吴效科黑龙江中医药大学哈尔滨150040 黑龙江中医药大学附属第一医院哈尔滨150040 徐州市中心医院徐州221009 黑龙江省医院哈尔滨150030

目的:分析不同中医证型多囊卵巢综合征(PCOS)不孕症女性接受克罗米芬治疗前后疗效变化的差异。方法:973例PCOS不孕症患者根据中医辨证分为肾虚肝郁证、肾虚血瘀证、脾虚痰湿证及痰瘀互结证。比较各证型患者使用克罗米芬或安慰剂治疗前... 详细信息

目的:分析不同中医证型多囊卵巢综合征(PCOS)不孕症女性接受克罗米芬治疗前后疗效变化的差异。方法:973例PCOS不孕症患者根据中医辨证分为肾虚肝郁证、肾虚血瘀证、脾虚痰湿证及痰瘀互结证。比较各证型患者使用克罗米芬或安慰剂治疗前后人口学特征、性激素水平、糖脂代谢水平及生殖结局变化的差异。结果:与安慰剂比较,克罗米芬使肾虚肝郁证、脾虚痰湿证及痰瘀互结证患者黄体生成素及卵泡刺激素水平较基线水平降低更显著,使各证型患者孕酮、雌二醇、总睾酮及性激素结合球蛋白水平较基线水平升高更显著,使脾虚痰湿证患者游离睾酮指数水平较基线水平降低更显著,使痰瘀互结证患者抗苗勒管激素水平较基线水平降低更显著(P<0.01,P<0.05);克罗米芬使肾虚血瘀证患者空腹血糖、空腹胰岛素及胰岛素抵抗指数水平较基线水平升高更显著(P<0.01);克罗米芬使肾虚血瘀证患者高密度脂蛋白及载脂蛋白A水平较基线水平升高更显著(P<0.05);克罗米芬使各证型患者排卵率显著提高,使肾虚肝郁证、脾虚痰湿证及痰瘀互结证患者受孕率、妊娠率及活产率显著提高(P<0.01,P<0.05)。结论:肾虚肝郁证、脾虚痰湿证及痰瘀互结证PCOS不孕症患者使用克罗米芬可降低促性腺激素水平、提高性激素水平及改善生殖结局;肾虚血瘀证患者使用克罗米芬虽可提高性激素及脂代谢水平,但却加重糖代谢异常且并不改善终点生殖结局。

关键词：中医辨证分型多囊卵巢综合征不孕症克罗米芬糖脂代谢生殖结局

Semen Analysis and Fecundity Association Among Women with Polycystic Ovary Syndrome Experiencing Ovulatory Dysfunction Treated by Ovulation Induction

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Engineering 2021年第11期7卷 1586-1591页

作者： jingshu gao Yu Wang Mubai Li Mengyi Zhu Xuekui Liu Hongli Ma Yijuan Cao Lu Li Xinming Yang Xiaoke Wu College of Pharmacy The Department of MedicineHangzhou Normal UniversityHangzhou 311121China First Affiliated Hospital Heilongjiang University of Chinese MedicineHarbin 150040China Clinical Medical College Heilongjiang University of Chinese MedicineHarbin 150040China Department of Endocrinology Xuzhou Central HospitalXuzhou 221009China College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China Department of Obstetrics and Gynecology The Chinese University of Hong KongHong Kong 999077China Institute of Chinese Medicine The Chinese University of Hong KongHong Kong 999077China Heilongjiang Provincial Hospital Harbin 150030China

In this study,normal values of semen analysis were set for a general infertile population of couples among which most women had normal *** predictive capacity values of sperm quality,including concentration,motile count,progressive motile count,and morphology,are unclear for women with polycystic ovary syndrome(PCOS).A secondary analysis was conducted based on a randomized controlled trial investigating infertility among women with PCOS experiencing ovulatory disorder between 2011 and 2016 in China.A total of 1000 women received ovulation induction(acupuncture and clomiphene).We randomized the women with PCOS in 27 hospitals in China who received one of four interventions(acupuncture plus clomiphene,sham acupuncture plus clomiphene,acupuncture plus placebo,or sham acupuncture plus placebo).Semen analysis was performed for every male partner according to the World Health Organization(WHO)*** outcomes included conception,clinical pregnancy,and live *** regression was used to evaluate the predictive value of semen analysis among ovulatory women for conception,clinical pregnancy,and live *** the 1000 couples,the number of couples who attained ovulation,conception,clinical pregnancy,and live birth were 780,320,235,and 205,*** volume and motility were applied and used as prediction parameters for conception(area under the curve(AUC)of 0.62(95%confidence interval(CI),0.55–0.69)),clinical pregnancy(AUC of 0.67(95%CI:0.61–0.73)),and live birth(AUC of 0.57(95%CI:0.50–0.64)).No poor calibration was shown for these models in Hosmer–Lemeshow *** predictive capacity of semen analysis for treatment outcome in PCOS women with PCOS experiencing with ovulatory dysfunction is limited.

关键词： Semen analysis Fecundity Ovulatory dysfunction Predictive capacity

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中医外治法在分娩镇痛中的应用

光明中医 2024年第16期39卷 3358-3360页

作者：李燕春杨玉涵耿珍珍黄欣欣殷勤丽高敬书牡丹江医学院黑龙江牡丹江157011 黑龙江中医药大学附属第一医院妇科一科黑龙江哈尔滨150040

近年来,中医外治法作为一种独特的疗法,在中医理论的指导下,取得了显著的成果,不仅能够有效缓解产妇的分娩疼痛,而且还具有简单、便捷、高效、经济实惠的优点,深受产妇青睐。笔者查阅文献,将近几年中医外治法在分娩镇痛的应用现状进行综... 详细信息

近年来,中医外治法作为一种独特的疗法,在中医理论的指导下,取得了显著的成果,不仅能够有效缓解产妇的分娩疼痛,而且还具有简单、便捷、高效、经济实惠的优点,深受产妇青睐。笔者查阅文献,将近几年中医外治法在分娩镇痛的应用现状进行综述,主要有针刺、芳香疗法及联合疗法等,并总结目前中医外治法在分娩镇痛中的优点和缺点,以期为临床治疗提供参考。

关键词：分娩镇痛中医外治法综述

Hospital-Based Phenotypic Features and Treatment Outcomes of Chinese Women with Polycystic Ovary Syndrome: The Effect of Body Mass Index and Geographic Distribution

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Engineering 2021年第2期7卷 170-177页

作者： jingshu gao Hongli Ma Yu Wang Xinming Yang Yijuan Cao Bei Zhang Conghui Han Xiaoke Wua First Affiliated Hospital Heilongjiang University of Chinese MedicineHarbin 150040China Xuzhou Central Hospital Xuzhou 221009China

Genetic,lifestyle,and environmental factors contribute to the etiology of polycystic ovary syndrome(PCOS).Increased body mass index(BMI)exacerbates the reproductive and metabolic parameters and reduces the fecundity of women with *** is a secondary analysis of a large-sample,multicenter,randomized controlled trial conducted at 21 sites in Chinese mainland.A total of 1000 women diagnosed with PCOS were enrolled in this *** these,998 women with PCOS were included in the *** BMI was associated with more severe menstrual irregularities,elevated testosterone level,higher prevalence of metabolic syndrome,and poorer quality of *** rates of ovulation per woman for the normal,overweight,and obese BMI groups were 83.0%,78.2%,and 63.6%,respectively(P<0.001),and the rates of live birth were 23.6%,18.1%,and 15.3%(P=0.030).Northern PCOS patients showed more severe reproductive,glucose,and lipid profiles;less exercise;and lower total ovulation rates compared with PCOS patients from Southern China(74.8%vs 81.2%,absolute difference 6.4%,95%confidence interval 1.2%–11.5%).The results show the typical phenotypic features of Han women with PCOS in Northern and Southern *** women living in Northern China showed a higher BMI,more severe glycolipid metabolism profiles,and subsequently worse clinical outcomes by the same interventions than those living in Southern *** difference in phenotypic features can be explained mostly by differences in BMI and the resulting difference in ovulation.

关键词： Polycystic ovary syndrome Body mass index Phenotype Chinese cohort Geographic distribution

Value of qualitative research in polycystic ovary syndrome

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Chinese Medical Journal 2014年第18期127卷 3309-3315页

作者： Ma Hongxia Liang Huiling gao jingshu Ma Hongli Liu Jianping Ng Hungyu Ernest Billhult Annika Stener-Victorin Elisabet Mu Xin Wu Xiaoke Department of Traditional Chinese Medicine First Affiliated Hospitalof Guangzhou Medical College Guangzhou Guangdong 510120China Department of Obstetrics and Gynecology National Key Disciplineand Clinical Base Heilongjiang University of Chinese MedicineHarbin Heilongjiang 150040 China School of Preclinical Medicine Beijing University of ChineseMedicine Beijing 100029 China Department of Obstetrics & Gynecology the University of HongKong Hong Kong China Research and Development Unit Primary Health Care VastraGotalandsregionen Borers Sweden Institute of Neuroscience and Physiology Department of PhysiologySahlgrenska Academy University of Gothenburg GothenburgSweden

Objective This article aims to introduce the benefits of qualitative research and to discuss how such research can be applied to the study of polycystic ovary syndrome （PCOS）. Data sources Relevant articles were published in English as of May 2013 from Pubmed. Terms ＂polycystic ovary syndrome/PCOS, qualitative research and methodology＂ were used for searching. Study selection Articles studying PCOS with qualitative methods were reviewed. Articles associated with the use of qualitative research in clinical research were cited. Results Six qualitative studies related to PCOS were found in the literature search. These studies addressed different aspects in PCOS women including their womanhood, lived experience, information need, and experience of treatment with acupuncture. Five of these six studies used phenomenology as guiding theory. Conclusion Quantitative research has been the dominant approach in the field so far, qualitative research is relevant to the advancement of PCOS.

关键词： polycystic ovary syndrome quantitative research qualitative research

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陶瓷与竹材在灯具设计中的组合应用

淮南师范学院学报 2016年第6期18卷 103-106页

作者：高婧淑南京工业大学浦江学院江苏南京211134

竹材产量丰富,生长速度快,纹理清晰美观,色泽清新自然,材质坚韧易弯曲,在我国得到广泛应用,形成了深厚的竹文化。陶瓷质地坚硬、色彩丰富,加工性能优越,也具有深厚的文化底蕴和独特的表现形式。竹材与陶瓷材料组合,在造型、材料性能、... 详细信息

竹材产量丰富,生长速度快,纹理清晰美观,色泽清新自然,材质坚韧易弯曲,在我国得到广泛应用,形成了深厚的竹文化。陶瓷质地坚硬、色彩丰富,加工性能优越,也具有深厚的文化底蕴和独特的表现形式。竹材与陶瓷材料组合,在造型、材料性能、工艺等很多方面都能够有效结合,充分发挥陶瓷和竹材的优点,取长补短。从竹材与陶瓷结合的可行性进行分析,对竹材与陶瓷色彩、工艺、文化等方面的组合进行探讨。

关键词：陶瓷竹材灯具设计组合