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Application of subharmonic-aided pressure estimation in a patient with giant hepatic cyst:A case report

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Portal Hypertension & Cirrhosis 2024年第2期3卷 124-127页

作者： Xiuyun Lu Jiaying Cao Yaozu Liu jingqin ma Jianjun Luo Yi Dong Wenping Wang Shanghai Institute of Medical Imaging ShanghaiChina Department of Ultrasound Zhongshan HospitalFudan UniversityShanghaiChina Department of Ultrasound Xinhua Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghaiChina Department of Interventional Radiology Zhongshan HospitalFudan UniversityShanghaiChina National Clinical Research Center for Interventional Medicine Zhongshan HospitalFudan UniversityShanghaiChina

Giant hepatic cysts may lead to impaired liver function by compressing surrounding tissue,resulting in symptoms such as nausea or portal ***-aided pressure estimation(SHAPE)offers a noninvasive method for quantitatively estimating pressure and monitoring interstitial fluid pressure.A 55-year-old female patient with giant hepatic cysts was admitted to our hospital with elevated protein electrophoretic gamma levels,likely caused by compression of important liver vessels by the *** surgery,B-mode ultrasound(BMUS)revealed multiple anechoic cystic lesions with thin,smooth walls in the right *** SHAPE,the curve of the portal vein was lower than that of the hepatic vein,which is absolutely different from a healthy volunteer in our previous SHAPE *** suggested that the patient may have had portal *** days after laparoscopic fenestration and drainage of hepatic cysts,the size of the largest cyst had decreased on BMUS and protein electrophoretic gamma levels had *** the curve of the portal vein remained lower than that of the hepatic vein,the difference between them had decreased compared to presurgery *** shows promise as a tool for noninvasively estimating portal hypertension and improving prognosis assessment in patients.

关键词： hepatic admitted impaired

Development of a Novel Endovascular Brachytherapy Stent:A Proof-of-concept Study

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Journal of Clinical and Translational Hepatology 2021年第5期9卷 711-718页

作者： Nan Du jingqin ma Zihan Zhang Yongjie Zhou Minjie Yang Wen Zhang Jianjun Luo Zhiping Yan Department of Interventional Radiology Zhongshan HospitalFudan UniversityShanghaiChina Shanghai Institution of Medical Imaging ShanghaiChina

Background and Aims:Endovascular implantation of iodine-125(125I)seeds strand combined with stent is an effective method of treatment for portal vein tumor *** aim of this study was to develop a novel endovascular brachytherapy stent(EVB-Stent)and to evaluate its feasibility of ***:An EVB-Stent was implanted into the main portal vein(MPV)in a live porcine model via the percutaneous transhepatic *** samples were collected and tested before and after operation,as well as before ***-photon emission computed tomography(SPECT)combined with CT(SPECT/CT)scan were performed directly after operation and CT scan was performed 2 months after *** the CT scan was performed,all animals were euthanized and histologically ***:The novel stent was successfully positioned in all six *** deterioration of liver function was observed during the 2-month follow-up ***/CT revealed the uniform distribution of radiation around the seeds strand,and the hottest spot was near the center of the *** patency of the stented MPV was confirmed using CT *** tissue-accumulated absorbed dose was 31,822.11 mGy at 10 mm transversely away from the midpoint of the 125I seeds strand,with a half-life of 59.4 *** examination results showed no significant atrophy or inflammation of adjunct liver tissue,and no obvious intima thickening or thrombosis were detected in the stented ***:A liver porcine model was used to demonstrate that the transhepatic placement of a novel endovascular brachytherapy stent,EVB-Stent,is both technically feasible and safe.

关键词： Portal vein tumor Tumor thrombus Brachytherapy Stent Iodine-125 seeds strand

Microwave ablation combined with transarterial chemoembolization containing doxorubicin hydrochloride liposome for treating primary and metastatic liver cancers

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Journal of Interventional Medicine 2023年第3期6卷 121-125页

作者： Qin Shi Zihan Zhang Wen Zhang jingqin ma Minjie Yang Jianjun Luo Lingxiao Liu Zhiping Yan Department of Interventional Radiology Zhongshan HospitalFudan UniversityShanghai200032China Shanghai Institution of Medical Imaging Shanghai200032China National Clinical Research Center for Interventional Medicine Zhongshan HospitalFudan UniversityShanghai200032China

Aims:To determine the safety and efficacy of microwave ablation(MWA)and transarterial chemoembolization(TACE)with doxorubicin hydrochloride liposome(DHL)in patients with primary liver cancer(PLC)and metastatic liver cancer(MLC).materials and methods:The medical records of patients with primary or metastatic liver cancer who underwent MWA combined with TACE containing DHL from march 2019 to march 2022 were collected and ***-related adverse events(AEs)were *** tumor response was evaluated according to the modified RECIST *** tumor progression-free survival(LTPFS)and overall survival(OS)were calculated using the Kaplan-Meier ***:Altogether,96 patients with liver cancer were included(PLC,n=45;MLC,n=51).Forty(41.7%)patients experienced AEs during treatment,and eight(8.3%)patients developed grade 3 *** to before treatment,the serum total bilirubin level and neutrophil to lymphocyte ratio significantly increased after *** median LTPFS was 14.5 months in patients with PLC and 10.7 months in patients with *** median OS was not reached in patients with PLC or *** 1-month and 3-month disease control rates reached more than 80%in both ***:MWA combined with TACE with DHL may be a safe and effective method for the treatment of liver cancer.

关键词： Liver cancer Doxorubicin hydrochloride liposome Transarterial chemoembolization Microwave ablation

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肝癌介入治疗进一步思考

介入放射学杂志 2019年第6期28卷 507-510页

作者：马婧嶔颜志平复旦大学附属中山医院介入治疗科上海市影像医学研究所

肝细胞肝癌是全球最常见的恶性肿瘤之一,发生率与死亡率均居前列。目前肝癌介入治疗在我国逐步得到推广及发展,取得了很大成就,但有些方面需要进一步思考。肝癌可视为一种慢性疾病,以介入为主综合治疗中晚期肝癌比较合理的目标是控制肿... 详细信息

肝细胞肝癌是全球最常见的恶性肿瘤之一,发生率与死亡率均居前列。目前肝癌介入治疗在我国逐步得到推广及发展,取得了很大成就,但有些方面需要进一步思考。肝癌可视为一种慢性疾病,以介入为主综合治疗中晚期肝癌比较合理的目标是控制肿瘤生长,延长有质量的生存期。但实现这一目标并非易事,需要不断更新观念,随时调整治疗策略。制定肝癌治疗方案时,必须考虑肿瘤治疗与维持正常机体功能的平衡,同时兼顾规范化与个体化治疗。肝癌生物学特性决定了肝癌治疗是长期、多学科、多方法的综合治疗。重视肝癌治疗的社会适应证、效价比及肝功能储备,对合理安排治疗时间和间期颇为重要。应在合理选择精细TACE和适度TACE基础上,理性对待新型栓塞材料。

关键词：肝癌经导管动脉化疗栓塞术介入治疗

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论近代西方哲学对体育哲学的影响

体育文化导刊 2005年第12期 24-25页

作者：马景芹于涛山东师范大学

西方哲学伴随着文艺复兴、宗教改革、自然科学革命等伟大历史事件的发生而实现了西方哲学发展史上的历史性转向,诞生了一个坚持主客体二元模式、主体性及重视方法论的新文化形态。而作为人类文化有机组成部分的体育哲学势愉会受这一哲... 详细信息

西方哲学伴随着文艺复兴、宗教改革、自然科学革命等伟大历史事件的发生而实现了西方哲学发展史上的历史性转向,诞生了一个坚持主客体二元模式、主体性及重视方法论的新文化形态。而作为人类文化有机组成部分的体育哲学势愉会受这一哲学文化形态的影响。本文在概括总结近代西方哲学总体特征的基础上,概述了其或积极或消极的影响。

关键词：近代西方哲学体育哲学二元模式主体性方法论

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门静脉系统血栓的介入治疗

临床肝胆病杂志 2018年第10期34卷 2053-2057页

作者：马婧嶔罗剑钧复旦大学附属中山医院介入科上海200032

随着门静脉系统血栓(PVT)的确诊率不断提高,针对PVT的介入治疗也日益受到重视。机械性碎栓及药物性溶栓配合全身性抗凝治疗能部分甚至完全地逆转门静脉血栓后的局部及全身性血流动力学改变,恢复门静脉血流,降低门静脉压力。介入治疗PVT... 详细信息

随着门静脉系统血栓(PVT)的确诊率不断提高,针对PVT的介入治疗也日益受到重视。机械性碎栓及药物性溶栓配合全身性抗凝治疗能部分甚至完全地逆转门静脉血栓后的局部及全身性血流动力学改变,恢复门静脉血流,降低门静脉压力。介入治疗PVT需根据不同情况选择合适的治疗方法及途径。经肠系膜上动脉途径创伤及风险相对较小,但对亚急性、慢性血栓或侧支已形成的单纯门静脉主干血栓溶栓效果多不理想。经门静脉途径是目前最常用的介入治疗手段,包括经皮穿肝、经皮穿脾和经肠系膜静脉等多种入路。经颈静脉肝内门体分流术治疗可为门静脉系统提供一个低阻力的流出道,降低门静脉压力、改善门静脉血流瘀滞。PVT的介入治疗是多手段多途径联合的综合介入治疗。根据病情分别或联合应用多种治疗途径及多种治疗手段能取得更好疗效并降低并发症和病死率。

关键词：静脉血栓形成门静脉外科手术,微创性

Uniform decomposition of velocity gradient tensor

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Journal of Hydrodynamics 2024年第1期36卷 24-34页

作者： Chenxi ma Chaoqun Liu Department of mathematics University of Texas at ArlingtonArlingtonTXUSA

In this paper,the principal decomposition of the velocity gradient tensor[∇v]is discussed in 3 cases based on the discriminant∆:∆0 with 3 distinct real eigen values,and∆=0 with 1 or 2 distinct real eigen *** velocity gradient tensor can also be classified as rotation point,which can be decomposed into three parts,i.e.,rotation[R],shear[S]and stretching/compression[SC],and non-rotation point,we defined a new resistance term[L],and the tensor can be decomposed into three parts,i.e.,resistance[L],shear[S]and stretching/compression[SC].Example matric are also displayed to demonstrate the new *** of principal decomposition between 3 different cases,and between Resistance and Liutex will also be discussed.

关键词： Velocity gradient Liutex resistance fluid kinematics

VOC emitted by biopharmaceutical industries:Source profiles,health risks,and secondary pollution

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Journal of Environmental Sciences 2024年第1期135卷 570-584页

作者： Jiawei ma Lin Li State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China National Engineering Laboratory for VOCs Pollution Control material&Technology University of Chinese Academy of SciencesBeijing 101408China

The biopharmaceutical industry contributes substantially to volatile organic compounds(VOCs)emissions,causing growing concerns and social developmental *** study conducted an on-site investigation of the process-based emission of VOCs from three biopharmaceutical *** the workshops of the three enterprises,26 VOCs were detected,which could be sorted into 4 classes:hydrocarbons,aromatic hydrocarbons,oxygen-containing compounds,and nitrogen-containing *** were the main components of waste gases,accounting for 44.13%-77.85%of the overall ***-based source profiles were compiled for each process unit,with the fermentation and extraction units of tiamulin fumarate being the main source of VOC *** heptanone,vinyl acetate,diethylamine,propylene glycol methyl ether(PGME),and benzene were screened as priority pollutants through a fuzzy comprehensive evaluation *** level concentration simulation results of the Gauss plume diffusion model demonstrated that the diffusivity of VOCs in the atmosphere was relatively high,indicating potential non-carcinogenic and carcinogenic risks 1.5-2 km ***,the process-based formation potentials of ozone and secondary organic aerosols(SOAs)were determined and indicated that N-methyl-2-pyrrolidone,dimethyl heptanone,and PGME should be preferentially controlled to reduce the ozone formation potential,whereas the control of benzene and chlorobenzene should be prioritized to reduce the generation of *** results provide a basis for understanding the characteristics of VOC emission by biopharmaceutical industries and their diffusion,potentially allowing the development of measures to reduce health risks and secondary pollution.

关键词： Biopharmaceutical Volatile organic compound Priority pollutant Exposure risk Secondary pollution

Deterministic and Robust Volt-var Control Methods of Power System Based on Convex Deep Learning

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 719-729页

作者： Qing ma Changhong Deng the School of Electrical Engineering and Automation Wuhan UniversityWuhanChina

Volt-var control(VVC)is essentially a non-convex optimization problem due to the non-convexity of power flow(PF)constraints,resulting in the difficulty in obtaining the optimum without convexity *** existing second-order cone method for the convexity conversion often leads to a sharp increase in PF constraints and optimization variables,which in turn increases the optimization difficulty or even leads to optimization *** paper first proposes a deterministic VVC method based on convex deep learning power flow(DLPF).This method uses the input convex neural network(ICNN)to establish a single convex mapping between state parameters and node voltage to complete the convexity conversion while the optimization variables only correspond to reactive power equipment,which can ensure the global optimum with extremely fast computation *** cope with the impact brought by the uncertainty of distributed energy and omit the additional worst scenario search of traditional robust VVC,this paper proposes robust VVC method based on convex deep learning interval power flow(DLIPF),which continues to adopt ICNN to establish another convex mapping between state parameters and node voltage *** DLIPF with DLPF,this method decreases the modeling and optimization difficulty of robust VVC *** results on 30-bus,118-bus,and 200-bus systems prove the correctness and rapidity of the proposed methods.

关键词： Volt-var control convexity conversion convex deep learning power flow