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Palaeoclimate of the Paleogene Dongying Formation in Bozhong Sag of Bohai Bay Basin

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Petroleum Research 2021年第4期6卷 368-378页

作者： Juan Zhang Chenchen wang jingmin wang Linbo wang Yunqian Jia Rongrong Hu College of Earth Sciences Yangtze UniversityWuhan430100HubeiChina Laboratory of Reservoir Microstructure Evolution and Digital Characterization Wuhan430100HubeiChina Cooperative Innovation Center of Unconventional Oil and Gas Yangtze UniversityWuhan430100China School of Petroleum Engineering Yangtze UniversityWuhan430100China

It was showed that the sedimentary environment of lacustrine basins is more susceptible to basin size than that of marine basins,leading to frequent changes in sedimentary environment and large differences in sediment supply and *** on the comprehensive analysis of clay minerals,spore pollen,major elements and trace elements,the sedimentary environment of Dongying Formation and its evolution in Bozhong Sag were *** results showed that during the sedimentary period of Dongying Formation,the study area was in a subtropical warm and humid climate as a *** addition,the vertical distribution of spore pollen and algae was divided into four zones and each one represents different sedimentary *** zone I is characterized by a large number of spore pollen and algae,including juglanspollenites verus,ulmipollemites minor,abietineaepollenites and pinuspollenites,taxodiaceaepollenites hiatus,leiosphaeridia and granodiscus,and it indicates a relatively hot and dry climatic;Combination zone II mainly contains juglanspollenites verus,ulmipollemites minor,abietineaepollenites and pinuspollenites,pediastrum and *** with I,the number of spore pollen and algae decreases,but the number of pediastrum increases a lot,which represents warm and humid *** combination zone III is dominated by abietineaepollenites and pinuspollenites and chaetosphaeridium,and the species and quantity decrease *** indicates a relatively hot and humid climate at that *** zone IV contains a small amount of spore pollen and algae,and it means the climate was warm and humid at that *** frequent changes of sedimentary environment in lacustrine basins are influenceded by regional tectonic environment and basin *** S/A and E-T parameters,the paleoclimate in the study area was delineated and 10 sedimentary environment interfaces were identified,which further illustrated the characteristics of frequent fluctuati

关键词： Clastic rocks Spore pollen assemblage zone Sedimentary environment Bozhong sag Lacustrine basin

A highly efficient open-shell singlet luminescent diradical with strong magnetoluminescence properties

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Light(Science & Applications) 2023年第12期12卷 2636-2643页

作者： Alim Abdurahman Li Shen jingmin wang Meiling Niu Ping Li Qiming Peng Jianpu wang Geyu Lu State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityQianjin Avenue 2699Changchun 130012China College of Chemical Engineering and Environmental Chemistry Weifang UniversityWeifang 261061China Key Laboratory of Flexible Electronics(KLOFE) Institute of Advanced Materials(IAM)&School of Flexible Electronics(Future Technologies)Nanjing Tech University(NanjingTech)30 South Puzhu RoadNanjing 211816China Key Laboratory for Organic Electronics and Information Displays&Institute of Advanced Materials(IAM)National Synergistic Innovation Center for Advanced Materials(SICAM) Nanjing University of Posts&Telecommunications9 Wenyuan RoadNanjing 210023China

Developing open-shell singlet(OS)diradicals with high luminescent properties and exceptional single-molecule magnetoluminescence(ML)performance is extremely ***,we propose a concept to enhance luminescent efficiency by adjusting the donor conjugation of OS diradicals,thereby achieving a highly luminescent diradical,DR1,with outstanding stability and making it a viable option for use in the emitting layer of organic light-emitting diodes(OLEDs).More importantly,the 0.5wt%-DR1 doped film demonstrates significant single-molecule magnetoluminescence(ML)properties.A giant ML value of 210%is achieved at a magnetic field of 7T,showing the great potential of DR1 in magneto-optoelectronic devices.

关键词： luminescence luminescent magneto

Preparation and evaluation of tamsulosin hydrochloride sustained-release pellets modified by two-layered membrane techniques

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Asian Journal of Pharmaceutical Sciences 2015年第1期10卷 31-39页

作者： jingmin wang Yinghua Sun Bo Li Rui Fan Bing Li Tengrui Yin Ling Rong Jin Sun Shenyang Pharmaceutical University No.103Wenhua RoadShenyang 110016China

The aim of the present study was to develop tamsulosin hydrochloride sustained-release pellets using two-layered membrane *** granulator and fluidizedbed coater were employed to prepare drug-loaded pellets and to employ two-layered membrane coating *** prepared pellets were evaluated for physicochemical characterization,subjected to differential scanning calorimetry(DSC)and in vitro release of different *** release models and scanning electron microscopy(SEM)were utilized to analyze the release mechanism of Harnual■ and home-made *** comparing the dissolution profiles,the ratio and coating weight gain of Eudragit■ NE30D and Eudragit■ L30D55 which constitute the inside membrane were identified as 18:1 and 10%-11%.The coating amount of outside membrane containing Eudragit■ L30D55 was determined to be 0.8%.The similarity factors(f_(2))of home-made capsule and commercially available product(Harnual■)were above 50 in different dissolution *** studies confirmed that drug and excipients had good compatibility and SEM photographs showed the similarities and differences of coating surface between Harnual■ and self-made pellets before and after *** to Ritger-Peppas model,the two dosage form had different release mechanism.

关键词： Preparation In vitro evaluation Tamsulosin hydrochloride Sustained-release pellets Drug release mechanism Stability study

SOA Information Engineering System Based on Knowledge Grid Applications in Smart Grids

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Electricity 2012年第4期23卷 16-19页

作者： wang jingmin Dong Bo North China Electric Power University

Smart grids have the characteristics of being observable,controllable,adaptive,self-healing,embedded independent processing,and real-time *** the development of smart grids,constructing a grid to cover global,unified information systems,which should be adapted to fulf ill the requirements of the characteristics,is *** paper presents an service-oriented architecture(SOA)for smart grid information-engineering systems based on knowledge grid,which could form as a service-oriented architecture through business,technology and management;it would extract potentially valuable information from the massive amount of information on the generation side,the grid side,and the electricity side,then share the useful information to improve availability,security and stability.

关键词： knowledge grid smart grid service-oriented architecture (SOA) information security

Superresolution live-cell imaging reveals that the localization of TMEM106B to filopodia in oligodendrocytes is compromised by the hypomyelination-related D252N mutation

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Science China(Life Sciences) 2023年第8期66卷 1858-1868页

作者： Shijia Xing Xiaolu Zheng Huifang Yan Yanquan Mo Ruoyu Duan Zhixing Chen Kunhao wang Kai Gao Tongsheng Chen Shiqun Zhao jingmin wang Liangyi Chen National Biomedical Imaging Center State Key Laboratory of Membrane BiologyBeijing Key Laboratory of Cardiometabolic Molecular MedicineInstitute of Molecular MedicineCollege of Future TechnologyPeking UniversityBeijing 100871China Department of Pediatrics Peking University First HospitalBeijing 100034China PKU-IDG/McGovern Institute for Brain Research Beijing 100871China National Biomedical Imaging Center Institute of Molecular MedicineCollege of Future TechnologyPeking UniversityBeijing 100871China Key Laboratory of Laser Life Science Ministry of EducationCollege of BiophotonicsSouth China Normal UniversityGuangzhou 510631China National Center for Children’s Health Department of NeurologyBeijing Children’s HospitalCapital Medical UniversityBeijing 100045China

Hypomyelination leukodystrophies constitute a group of heritable white matter disorders exhibiting defective myelin *** identified as a lysosomal protein,the TMEM106B D252N mutant has recently been associated with ***,how lysosomal TMEM106B facilitates myelination and how the D252N mutation disrupts that process are poorly *** used superresolution Hessian structured illumination microscopy(Hessian-SIM)and spinning discconfocal structured illumination microscopy(SD-SIM)to find that the wild-type TMEM106B protein is targeted to the plasma membrane,filopodia,and lysosomes in human *** D252N mutation reduces the size of lysosomes in oligodendrocytes and compromises lysosome changes upon starvation *** importantly,we detected reductions in the length and number of filopodia in cells expressing the D252N ***1 is the most abundant myelin protein that almost entirely colocalizes with TMEM106B,and coexpressing PLP1 with the D252N mutant readily rescues the lysosome and filopodia phenotypes of ***,interactions between TMEM106B and PLP1 on the plasma membrane are essential for filopodia formation and myelination in oligodendrocytes,which may be sustained by the delivery of these proteins from lysosomes via exocytosis.

关键词： superresolution imaging oligodendrocyte TMEM106B lysosome filopodia

Clinical Analysis of 45 Patients with Thymic Carcinoma

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Chinese Journal of Clinical Oncology 2009年第2期6卷 129-132页

作者： Ruitai Fan jingmin wang Hongzhi Zhang Yanna Guo Hao Gu Department of Radiotherapy the First Hospital of Zhengzhou University Henan 450052Zhengzhou Province China

OBJECTIVE To retrospectively evaluate the prognostic factorsfor advanced thymic *** The data from 45 patients with advanced thymiccarcinoma were retrospectively analyzed according to Masaokastage criteria. There were 29 Stage Ⅲ patients and 16 StageⅣ patients (13 Stage ⅣA patients and 3 Stage ⅣB patients).According to the World Heath Organization Histological Criteria(2004), 25 cases were identified as low-grade and 20 caseswere identified as high-grade. All diagnoses were confirmedby biopsy. Five patients underwent gross total resection, 21patients underwent subtotal resection and 19 patients underwentbiopsy alone. Forty-two patients received radiotherapy with amedian dose of 60 Gy, and 37 patients underwent conventionalradiotherapy, including local irradiation and expanded *** irradiation volume covered the primary tumor bed andapproximately 1-2 cm^2 surrounding the tumor (according topreoperative imaging). Expanded irradiation volume coveredthe full mediastinal and pericardium areas (with or withoutprophylactic irradiation in the supraclavicular area). Five casesreceived stereotactic radiotherapy. Thirty-one patients were alsotreated with chemotherapeutics, including Cisplatin, VP-16,Endoxan, 5-FU and *** The median follow-up period was 59 months. Theoverall 3-year survival rate was 57.8%, and the median survivalwas 45 months. Univariate statistical analysis showed that thehistological subtype and Masaoka stage were prognostic *** 3-year survival rate was 61.9% in patients treated withgross total resection and 55.0% in those who underwent biopsyonly. The 3-year survival rate was 59.5% in patients treatedwith conventional radiotherapy and 80% in those treated withstereotactic radiotherapy. The 3-year survival rate was 64.5% inpatients treated with simultaneous chemotherapy and 42.9%in patients treated without simultaneous chemotherapy (P >0.05). Chemotherapy in combination with radiation treatmentand surgery achieved b

关键词： thymic carcinoma combined modality therapy prognosis prognostic factors.

Neuregulin-1 therapy improved cardiac function and reduced ANPmRNA expression in post myocardial infarction rats with cardiac dysfunction

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Journal of Geriatric Cardiology 2005年第4期2卷 236-239页

作者： Yuanfang LI Naisheng CAI Xinghua GU jingmin ZHOU Keqiang wang Yunzeng ZOU Junbo GE Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Cardiovascular Disease Research InstituteShanghai 200032China

Objective To observe the influence of neuregulin-1 on the cardiac function of post-myocardial infarction *** Left ventricular MI was created in Sprague-Dawley rats by ligation of the left anterior descending *** months after the operation,rats were evaluated with echocardiology methods.36 rats that had an infarct area and a EF around 60%were randomized into 3 groups:MI group(n=12)were injected a blank vehicle fluid intravenously for 5 days,after which they continued to be raised on standard food and water for 30 ***+NRG group(n=12),received NRG-110μg·kg-^(1) intravenously for 5 days,after which they continued to be raised on standard food and water for 30 ***+Capt group(n=12)received captopril orally(dissolved in their drinking water 2g/L)for 30days,after which tap water substituted the solution for 5 *** echocardiographic and hemodynamic measurements were made at the end of 1 month of *** RNA was extracted from frozen left ventricular tissues,and was reverse transcribed into firststrand PCR was performed with primers for BNP、*** Rats treated with neuregulin had a smaller LVDs(P=0.014),a betterLVEF(P=0.004),and a tendency towards less lung perfusion than untreated *** decreased the expression of ANP mRNA in the ventricle(P=0.025).Conclusion Neuregulin markedly improved the cardiac function of rats that survived myocardial infarction,and decreased the expression of ANP mRNA in the ventricle.

关键词： neuregulin-1 myocardial infarction heart failure atrial natriuetic peptide

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杭州某高层建筑墙柱整体置换设计

建筑结构 2015年第17期45卷 37-39页

作者：王静民浙江省建筑科学设计研究院杭州310012

杭州某高层建筑,地上25层、地下1层,采用框架-剪力墙结构,主体结构已封顶。由于混凝土材料原因,17层柱、墙及18层梁的混凝土实际强度未达到设计要求,经专家论证,问题楼层须进行整体置换。通过设置临时钢支撑,分批置换混凝土竖向构件和... 详细信息

杭州某高层建筑,地上25层、地下1层,采用框架-剪力墙结构,主体结构已封顶。由于混凝土材料原因,17层柱、墙及18层梁的混凝土实际强度未达到设计要求,经专家论证,问题楼层须进行整体置换。通过设置临时钢支撑,分批置换混凝土竖向构件和水平构件,达到问题构件全部置换的目的,并通过了权威机构质量安全鉴定,取得了良好的经济效益和社会效益。

关键词：框架柱置换抱柱梁支撑钢管分批置换

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热磁耦合马氏体相变及其物理效应

稀有金属 2017年第5期41卷 505-514页

作者：蒋成保花慧王敬民北京航空航天大学材料科学与工程学院空天先进材料与服役教育部重点实验室北京100191

马氏体相变和磁性转变是两类典型的固态相变,其中,马氏体相变在钢铁等结构材料和形状记忆合金等功能材料中普遍存在,磁性转变在磁性材料中普遍存在。此前,这两类相变一直各自独立发生。在新型磁性形状记忆合金中发现了二者共同发生的热... 详细信息

马氏体相变和磁性转变是两类典型的固态相变,其中,马氏体相变在钢铁等结构材料和形状记忆合金等功能材料中普遍存在,磁性转变在磁性材料中普遍存在。此前,这两类相变一直各自独立发生。在新型磁性形状记忆合金中发现了二者共同发生的热磁耦合马氏体相变现象,此后基于该现象的磁场诱发相变及其引发的磁致应变、磁热、磁电阻等丰富的物理效应成为本领域的研究热点。本文综述了热磁耦合马氏体相变、磁场诱发相变及其物理效应等方面的研究进展,并对未来发展趋势做了展望。

关键词：磁性形状记忆合金热磁耦合马氏体相变磁场诱发相变物理效应