检索结果-南通市图书馆

Sign Changing Solution of a Semilinear Schrödinger Equation with Constraint

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics 2021年第6期12卷 489-499页

作者： jingkun liu Qi Fan Chengyi University College Jimei University Xiamen China Xiamen Sinic-Tek Intelligent Technology Co. Ltd. Xiamen China

The purpose of this paper is to study a semilinear Schrödinger equation with constraint in H1(RN), and prove the existence of sign changing solution. Under suitable conditions, we obtain a negative solution, a positiv... 详细信息

关键词： Semilinear Schrödinger Equation Sign Changing Solution Palais-Smale Condition Pseudo-Gradient Vector Field

An Improved Randomized Circle Detection Algorithm Using in Printed Circuit Board Locating Mark

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics 2019年第10期10卷 848-861页

作者： jingkun liu Qi Fan Chengyi University College Jimei UniversityXiamenChina Xiamen Sinic-Tek Intelligent Technology Co. Ltd.XiamenChina

This paper presents an improved Randomized Circle Detection (RCD) algorithm with the characteristic of circularity to detect randomized circle in images with complex background, which is not based on the Hough Transform. The experimental results denote that this algorithm can locate the circular mark of Printed Circuit Board (PCB).

关键词： Circle Detection Randomized Algorithm Characteristic of Circularity Printed Circuit Board

Single-cell Transcriptomic Analysis Reveals the Cellular Heterogeneity of Mesenchymal Stem Cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2022年第1期20卷 70-86页

作者： Chen Zhang Xueshuai Han jingkun liu Lei Chen Ying Lei Kunying Chen Jia Si Tian-yi Wang Hui Zhou Xiaoyun Zhao Xiaohui Zhang Yihua An Yueying Li Qian-Fei Wang CAS Key Laboratory of Genomic and Precision Medicine Collaborative Innovation Center of Genetics and DevelopmentBeijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China China National Center for Bioinformation Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China Department of Medical Experimental Center Qilu Hospital(Qingdao)Cheeloo College of MedicineShandong UniversityQingdao 266035China Qingdao Key Lab of Mitochondrial Medicine Qingdao 266035China International Department Liangxiang CampusBeijing University of Chinese MedicineBeijing 102401China Yihua Biotechnology Co. Ltd.Beijing 100041China Peking University People’s Hospital Peking University Institute of HematologyBeijing 100044China Department of Functional Neurosurgery Third Medical CenterGeneral Hospital of Chinese PLABeijing 100039China

Ex vivo-expanded mesenchymal stem cells(MSCs)have been demonstrated to be a heterogeneous mixture of cells exhibiting varying proliferative,multipotential,and immunomodulatory ***,the exact characteristics of MSCs remain largely *** singlecell RNA sequencing of 61,296 MSCs derived from bone marrow and Wharton’s jelly,we revealed five distinct *** developmental trajectory of these five MSC subpopulations was mapped,revealing a differentiation path from stem-like active proliferative cells(APCs)to multipotent progenitor cells,followed by branching into two paths:1)unipotent preadipocytes or 2)bipotent prechondro-osteoblasts that were subsequently differentiated into unipotent *** stem-like APCs,expressing the perivascular mesodermal progenitor markers CSPG4/MCAM/NES,uniquely exhibited strong proliferation and stemness ***,the prechondrocyte subpopulation specifically expressed immunomodulatory genes and was able to suppress activated CD3^(+T) cell proliferation in vitro,supporting the role of this population in *** summary,our analysis mapped the heterogeneous subpopulations of MSCs and identified two subpopulations with potential functions in self-renewal and *** findings advance the definition of MSCs by identifying the specific functions of their heterogeneous cellular composition,allowing for more specific and effective MSC application through the purification of their functional subpopulations.

关键词： Mesenchymal stem cell Single-cell RNA sequencing Heterogeneity Lineage trajectory Immune regulation

Protective effects of baicalin on amyloid beta 25-35-induced apoptosis in human neuroblastoma SH-SY5Y cells

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2010年第22期5卷 1739-1744页

作者： Miao Geng Hongyan Chen Jianhua Wang Yazhuo Hu Jianwei liu Jing liu jingkun Pan Yuhong Gao Institute of Geriatrics Division of South Building Chinese PLA General Hospital Beijing 100853 China

Baicalin, a type of flavanoid, effectively prevents cellular apoptosis induced by various factors. However, little evidence is available regarding its role on amyloid β （Aβ） -induced neuronal apoptosis. The present study investigated the protective mechanisms of baicalin on Aβ-induced neuronal apoptosis. Flow cytometry and cation dye 5, 5＇, 6, 6＇-tetrachloro-1, 1＇, 3, 3＇-tetraethyl- benzimidazoly lcarbocyanine iodide （JC-1） were employed to measure mitochondrial membrane potential, and nitric oxide secretion and apoptotic-related factors, such as caspase-3, were comprehensively analyzed. Results demonstrated a protective effect of baicalin on Aβ-treated SH-SY5Y cell viability; the rate of apoptosis decreased, nitric oxide generation and expression of caspase-3 were effectively inhibited, and mitochondrial membrane potential was effectively protected. Baicalin inhibited Aβ-induced neuronal apoptosis via multiple targets and multiple pathways, such as the inhibition of free radical damage, reduction of caspase-3 expression, and protection of normal mitochondrial functions.

关键词： baicalin neuron apoptosis traditional Chinese medicine caspase-3 amyloid β neural regeneration

Effects of Different Harvest Periods on Seed Quality of Alpinia oxyphylla Miq.

在线全文

学校读者我要写书评

暂无评论

Medicinal Plant 2018年第2期9卷 52-56,82页

作者： Hanting CHENG jingkun liu Tingliang YAN Qiaoyan ZHANG Jinchuang WANG Environment and Plant Protection Institute Chinese Academy of Tropical Agricultural Sciences/Danzhou Scientific Observing and Experimental Station of AgroEnvironmentMinistry of Agriculture

[Objectives] To clarify the appropriate harvest period of Alpinia oxyphylla Miq. seed and improve the quality of seeds. [Methods] In this experiment,the basic parameters and germination characteristics of A. oxyphylla Miq. seeds during different harvest periods were analyzed and compared. [Results] The results showed that the A. oxyphylla Miq. fruit picking period was closely related to the seed quality,and the seed maturity was highest 100 d after the flowering of A. oxyphylla Miq.,that is,the A. oxyphylla Miq. fruit skin turned from green to yellow( yellow-green),the peel had a small number of brown spots,it was spicy enough,the fruit dry/fresh weight ratio was greater than0. 34,the seed thousand kernel weight reached 11 g or more,and the dried seed moisture content was 13. 01%. Using the TTC method,the seed viability index was determined to be 85%,and in this case,it was the best time of harvesting seed. The water permeability of A. oxyphylla Miq. seed was poor,and the seed imbibition and water absorption time was long,about 72 h. The maximum water absorption rate was about23. 71% at the imbibition and water absorption stage,and it was inferred that the A. oxyphylla Miq. seeds were hard seeds. The germination time of A. oxyphylla Miq. seeds was long,the mature A. oxyphylla Miq. seeds began to germinate on the 12 th d,and the germination rate reached 75. 56% on the 50 th d. [Conclusions] This study determined the optimum harvest period of A. oxyphylla Miq. seeds,clarified the biological characteristics of slow seed water absorption and long germination cycle,and concluded that the seed coat was the main factor leading to slow seed water absorption and long seed germination cycle.

关键词： Alpinia oxyphylla Miq Germination Harvest period Water absorption rate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

以审判为中心的诉讼制度改革之立法思考

中国刑事法杂志 2019年第1期1卷 99-111页

作者：刘静坤中国政法大学诉讼法学研究院

推进以审判为中心的诉讼制度改革,是中央刑事司法体制改革的重要部署,目前尚待纳入立法修改日程。为通过立法深入推进改革,有必要重新审视改革与立法的关系,探索改革与立法梯次发展的新型模式。正视改革的立法需求,有必要聚焦刑事程序... 详细信息

推进以审判为中心的诉讼制度改革,是中央刑事司法体制改革的重要部署,目前尚待纳入立法修改日程。为通过立法深入推进改革,有必要重新审视改革与立法的关系,探索改革与立法梯次发展的新型模式。正视改革的立法需求,有必要聚焦刑事程序立法的核心问题,明确改革立法化的基本思路,使推进以审判为中心的诉讼制度改革落到实处。

关键词：以审判为中心诉讼制度制度共识立法化

在线全文

学校读者我要写书评

暂无评论

未来电力系统储能的新形态：云储能

电力系统自动化 2017年第21期41卷 2-8,16页

作者：康重庆刘静琨张宁电力系统及发电设备控制和仿真国家重点实验室清华大学北京市100084

风电与太阳能发电等间歇性可再生能源的快速发展增加了电力系统对储能的需求,共享经济的迅速发展为储能的应用带来新的商业机会,基于储能设施共享的云储能可能成为未来电力系统新的形态特征之一。云储能是一种基于电网的储能服务,它使... 详细信息

风电与太阳能发电等间歇性可再生能源的快速发展增加了电力系统对储能的需求,共享经济的迅速发展为储能的应用带来新的商业机会,基于储能设施共享的云储能可能成为未来电力系统新的形态特征之一。云储能是一种基于电网的储能服务,它使得用户可以随时、随地、按需使用电网级的共享储能资源池中的资源,可以显著地降低提供储能服务的成本。文中解释了云储能的概念,并对云储能商业模式的各个要素进行了详细阐述。在此基础上,分析了云储能的投资与规划、运行以及服务定价等关键问题,总结了当前的研究进展并提出了相关的研究思路与方法,探讨了未来为了促进云储能的发展与实施还需要着力解决的问题,对云储能未来的研究进行了简要的展望。

关键词：共享经济可再生能源能源互联网云储能

如何防止无辜者被强迫认罪——兼论不被强迫认罪权的程序要素

在线全文

学校读者我要写书评

暂无评论

政法论坛 2021年第3期39卷 70-82页

作者：刘静坤中国政法大学全面依法治国研究院

防止无辜者被强迫认罪,是健全错案防范机制、完善认罪认罚从宽制度不容回避的问题。基于错案的"冰山一角"观,无辜者被强迫认罪问题存在较大黑数。受有罪推定观念影响,侦查讯问方法存在内在的心理强制,犯罪嫌疑人认罪后容易固化有罪认定... 详细信息

防止无辜者被强迫认罪,是健全错案防范机制、完善认罪认罚从宽制度不容回避的问题。基于错案的"冰山一角"观,无辜者被强迫认罪问题存在较大黑数。受有罪推定观念影响,侦查讯问方法存在内在的心理强制,犯罪嫌疑人认罪后容易固化有罪认定的程序偏见,潜在重刑威胁可能扭曲认罪自愿性,这些都是强迫无辜者认罪的制度成因。为建立无罪推定型刑事程序,应当将不被强迫认罪权作为权利基础,规范犯罪嫌疑人认定的司法程序和证明标准,构建以查明真相为宗旨的新型调查型讯问制度,健全识别无辜者被强迫认罪的梯次性核查询问制度,完善避免反向歧视的认罪认罚从宽制度。

关键词：强迫认罪无罪推定调查型讯问核查询问认罪认罚从宽

在线全文

学校读者我要写书评

暂无评论

电力系统云储能研究框架与基础模型

中国电机工程学报 2017年第12期37卷 3361-3371页

作者：刘静琨张宁康重庆电力系统及发电设备控制和仿真国家重点实验室(清华大学电机系) 北京市海淀区100084

能源互联网不断发展促进了分布式储能使用需求迅速增长。目前储能设备成本依然较高,限制了分布式储能的广泛应用。为了解决这一问题,该文介绍了云储能这种新的储能共享模式,分析了其运行机制和商业模式。在此基础上从运营、对象、市场... 详细信息

能源互联网不断发展促进了分布式储能使用需求迅速增长。目前储能设备成本依然较高,限制了分布式储能的广泛应用。为了解决这一问题,该文介绍了云储能这种新的储能共享模式,分析了其运行机制和商业模式。在此基础上从运营、对象、市场三条主线提出了云储能的研究框架,分析云储能研究中的科学问题和关键技术。建立了云储能基础模型,提出了云储能提供商模型控制预测运行决策方法,可以有效应对用户使用云储能服务时充放电需求的不确定性。基于实际数据的算例分析证明了该方法的有效性。

关键词：电力系统运行分布式储能光伏集中式储能模型预测控制虚拟储能云储能