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Experimental Study of Effects of One Kind of Tangentially Non-uniform Tip Clearance on the Flow Field at an Exit of a Compressor Cascade Passage

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Journal of Thermal Science 2010年第1期19卷 7-13页

作者： Hongwei MA jinghui zhang Jun zhang School of Jet Propulsion Beihang University Beijing 100191 China National Key Laboratory of Science and Technology on Aero-Engines Beijing 100191 China

This paper presents an experimental investigation of effects of one kind of tangentially non-uniform tip clearance on the flow field at an exit of a compressor cascade *** tests were performed in a low-speed large-scale cascade with the uniform tip clearance and the non-uniform *** three-dimensional flow field was measured at the exit at three incidence angles of 0°,5°,and 8° using a mini five-hole pressure *** measurement results show that the non-uniform tip clearance can moderate the leakage flow and blow down more low-energy fluids at the tip corner and decrease the accumulation of low-energy fluids which cause the flow blockage in the blade *** the meantime,the non-uniform clearance can weaken the tangential migration of the low-energy fluids in the endwall boundary layer and reduce the secondary loss and the flow blockage in the tip region.

关键词： compressor cascade clearance leakage flow secondary flow vortex

Mapping genetic variations in the first assembled human genome

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Quantitative Biology 2021年第4期9卷 361-365页

作者： jinghui zhang Department of Computational Biology St.Jude Children's Research HospitalMemphisTN 38105-3678USA

On June 26,2000,President Bill Clinton held aceremony at the White House announcing the completion of the human genome ***,the leaders of the two competing groups,*** Collins from the National Institute of Health,and *** Venter from Celera Genomics,shook their *** a scientist who had been actively involved in both the public and private sides of human genome sequencing,I can still feel the excitement of being a contributor of this landmark scientific project even after 20 ***,I can also attest the significance of this achievement as the reference human genome sequence is being used every day by my research team to find cures for pediatric *** this feature I would like to present a foot soldier’s account on assembling and analyzing the sequence of the human genome.

关键词： Mapping Clinton pediatric

Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway

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Acta Pharmaceutica Sinica B 2020年第1期10卷 186-194页

作者： jinghui zhang Zhou Yu Guofeng You Department of Pharmaceutics RutgersThe State University of New JerseyPiscatawayNJ 08854USA

Organic anion transporter 3(OAT3)plays a vital role in removing a broad variety of anionic drugs from kidney,thus avoiding their possible toxicity in the *** the current study,we investigated the role of insulin-like growth factor 1(IGF-1)in the regulation of *** showed that IGF-1 induced a dose-and time-dependent increase in OAT3 transport activity,which correlated well with an increase in OAT3 *** IGF-1-induced increase in OAT3 expression was blocked by protein kinase A(PKA)inhibitor ***,IGF-1 induced an increase in OAT3 phosphorylation,which was also blocked by *** data suggest that the IGF-1 modulation of OAT3 occurred through PKA signaling *** further confirm the involvement of PKA,we treated OAT3-expressing cells with PKA activator Bt’2-cAMP,followed by examining OAT activity and *** showed that OAT3 activity and phosphorylation were much enhanced in Bt2-cAMP-treated cells as compared to that in control ***,linsitinib,an anticancer drug that blocks the IGF-1 receptor,abrogated IGF-1-stimulated OAT3 transport *** conclusion,our study demonstrated that IGF-1 regulates OAT3 expression and transport activity through PKA signaling pathway,possibly by phosphorylating the transporter.

关键词： Organic anion transporter Drug transport Regulation IGF-1 PKA Phosphorylation

Effects of a Kind of Surface Groove on Flow Loss in Both Rectangular and Circular Ducts at Different Reynolds Numbers

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Journal of Thermal Science 2016年第5期25卷 389-393页

作者： MA Rong MA Hongwei zhang Zhenyang zhang jinghui National Key Laboratory of Science and Technology on Aero-Engines Collaborative Innovation Center of Advanced Aero-EngineSchool of Energy & Power EngineeringBeihang University

Pipes are widely used to transport gas,oil and water in *** reduction in pipes is an increasingly concerned problem to save *** researches have indicated that the non-smooth surface with special structures can reduce flow *** this paper,an experimental investigation has been performed on the effects of a kind of surface groove on the drag in both rectangular and circular duct at different Reynolds *** the experiment of the rectangular duct,total pressure at both inlet and outlet were *** pressure on the wall was measured on the surface with smooth and grooved film *** the circular duct,a boundary layer pressure probe was used to measure the total pressure distribution at both inlet and *** taps at inlet and outlet were used to measure static *** loss coefficient is used to evaluate the effects of the surface groove on drag *** experiment was conducted with the Reynolds number range from 1.28×10~4 to 2.57×10~*** result shows a maximum drag loss reduction of approximately 2.4% in rectangular duct at Reynolds number of 2.4×10~4.A 10%reduction of pipe pressure loss by grooved surface is measured in circular duct at a Reynolds number of 3.0×10~5.

关键词： drag reduction surface groove rectangular duct circular duct

Efficient Location-Aware Data Placement for Data-Intensive Applications in Geo-distributed Scientific Data Centers

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Tsinghua Science and Technology 2016年第5期21卷 471-481页

作者： jinghui zhang Jian Chen Junzhou Luo Aibo Song School of Computer Science and Engineering Southeast University Nanjing 211189 China

Recent developments in cloud computing and big data have spurred the emergence of data-intensive applications for which massive scientific datasets are stored in globally distributed scientific data centers that have a high frequency of data access by scientists worldwide. Multiple associated data items distributed in different scientific data centers may be requested for one data processing task, and data placement decisions must respect the storage capacity limits of the scientific data centers. Therefore, the optimization of data access cost in the placement of data items in globally distributed scientific data centers has become an increasingly important *** data placement approaches for geo-distributed data items are insufficient because they either cannot cope with the cost incurred by the associated data access, or they overlook storage capacity limitations, which are a very practical constraint of scientific data centers. In this paper, inspired by applications in the field of high energy physics, we propose an integer-programming-based data placement model that addresses the above challenges as a Non-deterministic Polynomial-time（NP）-hard problem. In addition we use a Lagrangian relaxation based heuristics algorithm to obtain ideal data placement solutions. Our simulation results demonstrate that our algorithm is effective and significantly reduces overall data access cost.

关键词： data placement geo-distributed data center Lagrangian relaxation

A Dynamic and Deadline-Oriented Road Pricing Mechanism for Urban Traffic Management

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Tsinghua Science and Technology 2022年第1期27卷 91-102页

作者： Jiahui Jin Xiaoxuan Zhu Biwei Wu jinghui zhang Yuxiang Wang the School of Computer Science and Engineering Southeast UniversityNanjing 211189China the Department of Computer Science and Engineering Hangzhou Dianzi UniversityHangzhou 310018China

Road pricing is an urban traffic management mechanism to reduce traffic ***,most of the road pricing systems based on predefined charging tolls fail to consider the dynamics of urban traffic flows and travelers’demands on the arrival *** this paper,we propose a method to dynamically adjust online road toll based on traffic conditions and travelers’demands to resolve the above-mentioned *** method,based on deep reinforcement learning,automatically allocates the optimal toll for each road during peak hours and guides vehicles to roads with lower toll ***,it further considers travelers’demands to ensure that more vehicles arrive at their destinations before their estimated arrival *** method can increase the traffic volume effectively,as compared to the existing static mechanisms.

关键词： road pricing traffic congestion al eviation deep reinforcement learning

Photoinduced Radical-Ionic Transfer of Various Chlorofluorocarbons to Alkenes from Oxime-Based Surrogates

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CCS Chemistry 2024年第5期6卷 1222-1230页

作者： jinghui zhang Muliang zhang Martin Oestreich Institut für Chemie Technische Universität Berlin10623 Berlin Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry University of Science and Technology of ChinaHefei 230026

Functional-group-transfer strategies that avoid the use of unsustainable chemicals are attractive for the development of green ***(CFCs)not only contribute to the depletion of the stratospheric ozone layer,but their gaseous nature also poses a serious threat in scientific ***,the design of effective and sustainable alternatives to CFCs is highly ***,a practical CFC transfer platform for the addition of both a fluoroalkyl group and a chlorine substituent across alkenes by a photomediated redox-neutral manifold using bench-stable and easy-to-handle oxime-based surrogates is *** distinct reactivity of these tunable reagents allows for their single-electron reduction to trigger fragmentation driven by benzonitrile formation and loss of carbon *** other fragments released in that step,namely an electrophilic fluoroalkyl radical and a nucleophilic chloride anion,are subsequently transferred onto alkenes by a radical-ionic mechanism to deliver the desired chlorofluorocarbon products.

关键词： alkenes chlorofluorocarbons functionalgroup transfer radical-ionic crossover photoredox catalysis

Community Detection in Aviation Network Based on K-means and Complex Network

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Computer Systems Science & Engineering 2021年第11期39卷 251-264页

作者： Hang He Zhenhan Zhao Weiwei Luo jinghui zhang Civil Aviation Flight University of China Guanghan618307China WebChain Pty Ltd SydneyNSW 2118Australia

With the increasing number of airports and the expansion of their scale,the aviation network has become complex and *** order to investigate the complex network characteristics of aviation networks,this paper constructs a Chinese aviation network model and carries out related research based on complex network theory and K-means ***,the P-space model is employed to construct the Chinese aviation network ***,complex network indicators such as degree,clustering coefficient,average path length,betweenness and coreness are selected to investigate the complex characteristics and hierarchical features of aviation networks and explore their ***,using K-means clustering algorithm,five values are obtained as the initial clustering parameter K values for each of the aviation network hierarchies classified according to five complex network ***,clustering simulation experiments are conducted to obtain the visual clustering results of Chinese aviation network nodes under different K values,as well as silhouette coefficients for evaluating the clustering effect of each indicator in order to obtain the hierarchical classification of aviation networks under different ***,the silhouette coefficient is optimal when the K value is ***,the clustering results of the four layers of the aviation network can be *** to the experimental results,the complex network association discovery method combined with K-means algorithm has better applicability and simplicity,while the accuracy is improved.

关键词： K-means algorithm complex network community detection aviation network

supported by the National Natural Science Foundation of China(Nos.62172051,61772085,and 61877005)and Jiangsu Agriculture Science and Technology Innovation Fund(***(18)3054).

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Tsinghua Science and Technology 2023年第1期28卷 82-92页

作者： jinghui zhang Yuchen Wang Tianyu Huang Fang Dong Wei Zhao Dian Shen School of Computer Science and Engineering Southeast UniversityNanjing 211189China Hefei Comprehensive National Science Center Hefei 231299China School of Computer Science and Technology Anhui University of TechnologyHefei 230026China Department of Computer Science&Engineering The Chinese University of Hong KongHong Kong 999077China

Numerous neural network(NN)applications are now being deployed to mobile *** applications usually have large amounts of calculation and data while requiring low inference latency,which poses challenges to the computing ability of mobile ***,devices’life and performance depend on ***,in many scenarios,such as industrial production and automotive systems,where the environmental temperatures are usually high,it is important to control devices’temperatures to maintain steady *** this paper,we propose a thermal-aware channel-wise heterogeneous NN inference *** contains two parts,the thermal-aware dynamic frequency(TADF)algorithm and the heterogeneous-processor single-layer workload distribution(HSWD)*** on a mobile device’s architecture characteristics and environmental temperature,TADF can adjust the appropriate running speed of the central processing unit and graphics processing unit,and then the workload of each layer in the NN model is distributed by HSWD in line with each processor’s running speed and the characteristics of the layers as well as heterogeneous *** experimental results,where representative NNs and mobile devices were used,show that the proposed method can considerably improve the speed of the on-device inference by 21%–43%over the traditional inference method.

关键词： neural network inference mobile device temperature adjustment channel-wise parallelization