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Biomimetic porous silicon oxycarbide ceramics with improved specific strength and efficient thermal insulation

Journal of Materials Science & Technology 2024年第1期168卷 185-193页

作者： Zhuoqing Zhang jinghan li Lei Cao Yu Shi Huajie Yang Rui Yang Fan Xie Xing Zhang Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China School of Materials Science and Engineering Shenyang Ligong UniversityShenyang 110159China Shenyang Aircraft Design and Research Institute Shenyang 110035China

Considering the challenge of aerodynamic heating,the development of high-performance insulating ce-ramic materials with lightweight and low thermal conductivity is crucially important for aerospace vehi-cles to achieve flight at high speed for a long time.In this work,macro-porous silicon oxycarbide(SiOC)ceramics with directional pores(DP-SiOC)(mean pore size of 88.1μm)were prepared using polysiloxane precursors via freeze casting and photocrosslinking,followed by pyrolysis.The DP-SiOC samples were lightweight(density∼0.135 g cm^(-3))with a porosity of 90.4%,which showed good shapability through the molding of polysiloxane precursors.The DP-SiOC samples also exhibited an ultra-low thermal con-ductivity of 0.048 W(m K)^(-1)at room temperature,which can also withstand heat treatment at 1200°C for 1 h.In addition,scaffolds with triply periodic minimal surfaces(TPMS)were fabricated using digital light processing(DLP)printing,which was further filled with polysiloxane precursors for increasing the strength of DP-SiOC.The TPMS scaffolds filled with macro-porous SiOC ceramics(TPMS-DP-SiOC)showed good integration between TPMS and macro-pore structures,which had a porosity∼75%and high specific strength of 9.73×10^(3)N m kg^(-1).The thermal conductivity of TPMS-DP-SiOC samples was 0.255 W(m K)^(-1)at room temperature.The biomimetic TPMS-DP-SiOC ceramics developed in this study are likely used for thermal protection systems.

关键词： Thermal insulation light weight Macro-porous ceramics SiOC

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Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance

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Genes & Diseases 2024年第4期11卷 98-101页

作者： jinghan Wang Xin Ku Qiuling Ma Haikuo li Sujuan Huang liping Mao Fang Yu Jie Jin Wei Yan Department of Hematology The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China Key Laboratory of Hematologic Malignancies Diagnosis and TreatmentHangzhouZhejiang 310003China Zhejiang Provincial Clinical Research Center for Hematologic Diseases HangzhouZhejiang 310003China Cancer Center Zhejiang UniversityHangzhouZhejiang 310003China Shanghai Center for Systems Biomedicine Key Laboratory of Systems Biomedicine(Ministry of Education)Shanghai JiaoTong UniversityShanghai 200240China The Second School of Clinical Medicine Henan University of Chinese MedicineZhengzhouHenan 450046China Department of Pathology The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China

Diffuse large B-cell lymphoma(DLBCL)is the most common subtype of B-cell lymphoma in adult patients.Due to the clinical and molecular heterogeneity of DLBCL patients,robust biomarkers in clinical practice are still re... 详细信息

关键词： clinical lymphoma patients

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From VIB‑to VB‑Group Transition Metal Disulfides:Structure Engineering Modulation for Superior Electromagnetic Wave Absorption

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Nano-Micro Letters 2024年第2期16卷 218-257页

作者： Junye Cheng Yongheng Jin jinghan Zhao Qi Jing Bailong Gu Jialiang Wei Shenghui Yi Mingming li Wanli Nie Qinghua Qin Deqing Zhang Guangping Zheng Renchao Che Department of Materials Science Shenzhen MSU-BIT UniversityShenzhen 517182People’s Republic of China School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China School of Materials Science and Engineering Qiqihar UniversityQiqihar 161006People’s Republic of China Department of Mechanical Engineering Hong Kong Polytechnic UniversityHung HomKowloonHong KongPeople’s Republic of China Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsFudan UniversityShanghai 200438People’s Republic of China Zhejiang Laboratory Hangzhou 311100People’s Republic of China

The laminated transition metal disulfides(TMDs),which are well known as typical two-dimensional(2D)semiconductive materials,possess a unique layered structure,leading to their wide-spread applications in various fields,such as catalysis,energy storage,sensing,etc.In recent years,a lot of research work on TMDs based functional materials in the fields of electromagnetic wave absorption(EMA)has been carried out.Therefore,it is of great significance to elaborate the influence of TMDs on EMA in time to speed up the application.In this review,recent advances in the development of electromagnetic wave(EMW)absorbers based on TMDs,ranging from the VIB group to the VB group are summarized.Their compositions,microstructures,electronic properties,and synthesis methods are presented in detail.Particularly,the modulation of structure engineering from the aspects of heterostructures,defects,morphologies and phases are systematically summarized,focusing on optimizing impedance matching and increasing dielectric and magnetic losses in the EMA materials with tunable EMW absorption performance.Milestones as well as the challenges are also identified to guide the design of new TMDs based dielectric EMA materials with high performance.

关键词： Transition metal disulfides Electromagnetic wave absorption Impedance matching Structure engineering modulation

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Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey

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Virologica Sinica 2024年第2期39卷 290-300页

作者： Suqin Duan Wei Zhang Yongjie li Yanyan li Yuan Zhao Weihua Jin Quan liu Mingxue li Wenting Sun lixiong Chen Hongjie Xu Jie Tang jinghan Hou Zijun Deng Fengmei Yang Shaohui Ma Zhanlong He Institute of Medical Biology Chinese Academy of Medical Sciences Medical Primate Research Center Peking Union Medical CollegeYunnan Key Laboratory of Vaccine Research Development on Severe Infectious DiseaseKunming650118China

Coxsackievirus B3(CVB3)is the pathogen causing hand,foot and mouth disease(HFMD),which manifests across a spectrum of clinical severity from mild to severe.However,CVB3-infected mouse models mainly demonstrate viral myocarditis and pancreatitis,failing to replicate human HFMD symptoms.Although several enteroviruses have been evaluated in Syrian hamsters and rhesus monkeys,there is no comprehensive data on CVB3.In this study,we have first tested the susceptibility of Syrian hamsters to CVB3 infection via different routes.The results showed that Syrian hamsters were successfully infected with CVB3 by intraperitoneal injection or nasal drip,leading to nasopharyngeal colonization,acute severe pathological injury,and typical HFMD symptoms.Notably,the nasal drip group exhibited a longer viral excretion cycle and more severe pathological damage.In the subsequent study,rhesus monkeys infected with CVB3 through nasal drips also presented signs of HFMD symptoms,viral excretion,serum antibody conversion,viral nucleic acids and antigens,and the specific organ damages,particularly in the heart.Surprisingly,there were no significant differences in myocardial enzyme levels,and the clinical symptoms resembled those often associated with common,mild infections.In summary,the study successfully developed severe Syrian hamsters and mild rhesus monkey models for CVB3-induced HFMD.These models could serve as a basis for understanding the disease pathogenesis,conducting pre-trial prevention and evaluation,and implementing post-exposure intervention.

关键词： Coxsackievirus B3(CVB3) Hand foot and mouth disease(HFMD) Animal models Syrian hamster Rhesus monkey

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Sugarcane leaves-derived polyphenols alleviate metabolic syndrome and modulate gut microbiota of ob/ob mice

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Food Science and Human Wellness 2024年第2期13卷 633-648页

作者： li Sun Tao Wang Baosong Chen Cui Guo Shanshan Qiao jinghan lin Huan liao Huanqin Dai Bin Wang Jingzu Sun Hongwei liu State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Savaid Medicine School University of Chinese Academy of SciencesBeijing 100101China Guangxi Academy of Sciences Nanning 530007China

Sugarcane leaves-derived polyphenols(SLP)have been demonstrated to have diverse health-promoting benefits,but the mechanism of action has not been fully elucidated.This study aimed to investigate the anti-metabolic disease effects of SLP and the underlying mechanisms in mice.In the current study,we prepared the SLP mainly consisting of three flavonoid glycosides,three phenol derivatives,and two lignans including one new compound,and further demonstrated that SLP reduced body weight gain and fat accumulation,improved glucose and lipid metabolism disorders,ameliorated hepatic steatosis,and regulated short-chain fatty acids(SCFAs)production and secondary bile acids metabolism in ob/ob mice.Notably,SLP largely altered the gut microbiota composition,especially enriching the commensal bacteria Akkermansia muciniphila and Bacteroides acidifaciens.Oral gavage with the above two strains ameliorated metabolic syndrome(MetS),regulated secondary bile acid metabolism,and increased the production of SCFAs in high-fat diet(HFD)-induced obese mice.These results demonstrated that SLP could be used as a prebiotic to attenuate MetS via regulating gut microbiota composition and further activating the secondary bile acids-mediated gut-adipose axis.

关键词： Sugarcane leaves-derived polyphenols Metabolic syndrome Bacteroides acidifaciens Akkermansia muciniphila Secondary bile acids metabolism

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THE SCIENCE AND TECHNOLOGY BACKYARD AS A LOCAL LEVEL INNOVATION INTERMEDIARY IN RURAL CHINA

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Frontiers of Agricultural Science and Engineering 2022年第4期9卷 558-576页

作者： jinghan li Cees LEEUWIS Nico HEERINK Weifeng ZHANG Knowledge Technology and Innovation GroupWageningen University&ResearchWageningen 6706KNthe Netherlands Development Economics Group Wageningen University&ResearchWageningen 6706KNthe Netherlands College of Resources and Environmental Science China Agricultural UniversityBeijing 100193China College of Resources and Environment Anhui Agricultural UniversityHefei 230036China

Agricultural innovation can be described as a coevolutionary process of technological innovation,symbolic change,and social or institutional innovation,which relies on the interactions and collaboration between multiple stakeholders.This view emphasizes the significance of innovation intermediaries in supporting the coevolution process of innovation.Many studies have provided evidence on how innovation intermediaries play roles in supporting the coevolution innovation process at a broader innovation system level.However,little emphasis has been given to the role of innovation intermediaries in supporting the coevolution process of innovation at the community level in rural China.To address this research gap,this paper offers a case study of a novel type of innovation support intervention designed to promote technical change at the community level,the Science and Technology Backyard(STB).The paper focuses on the efforts of a specific STB in Wangzhuang village to promote innovation in tillage methods in wheat production.The aims was to examine the role of this newly emerging innovation support intervention in supporting the coevolution process of innovation at the community level,and compare the outcome of the coevolution process in the village with an STB to that in villages without an STB.Innovation journey analysis is applied to understand the evolved intermediation roles in the innovation process,and multivariate regression analysis is employed to assess the outcome of the coevolution process in villages with and without an STB.The findings suggest that the roles of STBs have evolved from knowledge brokers to systemic innovation intermediaries that facilitate the coevolution process of innovation inside an STB village.It has led to a higher adoption rate of improved technology,a better enabling environment for learning,and more effective institutional support in STB villages than in non-STB villages.However,the effect of support provided by a single STB on the coevolution process outside the community was limit

关键词： agricultural innovation coevolution community level innovation intermediaries Science and Technology Backyards(STBs)

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适应能源转型发展的输配电价动态激励机制研究

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电网技术 2024年第6期48卷 2511-2519,I0070,I0071页

作者：周静涵何永秀李润菎吕媛黄成华北电力大学经济与管理学院北京市昌平区102206 新能源电力与低碳发展研究北京市重点实验室北京市昌平区102206 国网江苏省电力有限公司电力科学研究院江苏省南京市211103

在能源转型的背景下,“重约束,轻激励”的输配电定价方式已不适应输配电网络低碳、安全、高效转型的发展需求。因此,该文设计了一种激励与约束相容的输配电价动态激励机制,研究表明:转型阶段下,需要进一步通过优化电网投资结构,减少投... 详细信息

在能源转型的背景下,“重约束,轻激励”的输配电定价方式已不适应输配电网络低碳、安全、高效转型的发展需求。因此,该文设计了一种激励与约束相容的输配电价动态激励机制,研究表明:转型阶段下,需要进一步通过优化电网投资结构,减少投资冗余来提高输配电网络运营效率,电网仍是成本超支风险的主要承担者;省级电网的低碳、安全、高效之间的耦合协调程度整体呈现为逐年提升;所提激励机制兼顾差异性和公平性,有利于各省输配电网的清洁、低碳、可持续发展。

关键词：新型电力系统输配电价数据包络分析耦合协调动态激励机制

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基于状态估计的大规模新能源送出线路纵联保护

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电网技术 2024年第5期48卷 2189-2198,I0113,I0114页

作者：聂铭李猛和敬涵刘颖王紫琪宋晓帆李强北京交通大学电气工程学院北京市海淀区100044 国网经济技术研究院有限公司北京市昌平区102209 国网河南省电力公司经济技术研究院河南省郑州市450000 国网山西省电力公司经济技术研究院山西省太原市030024

“双碳”背景下,加快构建清洁低碳、安全高效的能源体系,已成为国家重大需求。但是,新能源电源等值内电势不稳定,与传统同步机电源特性存在本质差异,换流器控制导致故障电流幅值受限、相位受控,现有工频量保护性能下降,威胁电网安全稳... 详细信息

“双碳”背景下,加快构建清洁低碳、安全高效的能源体系,已成为国家重大需求。但是,新能源电源等值内电势不稳定,与传统同步机电源特性存在本质差异,换流器控制导致故障电流幅值受限、相位受控,现有工频量保护性能下降,威胁电网安全稳定。该文提出基于状态估计的大规模新能源送出线路纵联保护原理,在考虑线路分布电容的基础上建立精确的线路模型,利用瞬时值的状态估计冗余特性提升了保护的速动性和可靠性,通过比较所建模型与实际模型匹配程度判别故障。仿真表明,所提保护方法能快速可靠判别各种类型的区内、外故障,保护判别时间不超过2ms,并具有较好的耐过渡电阻和抗干扰能力。

关键词：新能源电源纵联保护状态估计贝瑞隆模型

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基于图结构的空间同位模式挖掘

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测绘学报 2024年第4期53卷 724-735页

作者：王靖涵艾廷华吴昊徐海江栗广岳武汉大学资源与环境科学学院湖北武汉430079 地理信息系统教育部重点实验室湖北武汉430079 测绘遥感信息工程国家重点实验室湖北武汉430079

空间同位模式反映了不同地理要素分布的依存关系,是地理学第一定律的体现,也符合空间大数据分析重在揭示事物关联特征的目标。空间同位模式挖掘需要顾及空间分布耦合机制,探测空间邻近关系及基于支持度等指标分析高频共生模式。现有方... 详细信息

空间同位模式反映了不同地理要素分布的依存关系,是地理学第一定律的体现,也符合空间大数据分析重在揭示事物关联特征的目标。空间同位模式挖掘需要顾及空间分布耦合机制,探测空间邻近关系及基于支持度等指标分析高频共生模式。现有方法多在判定邻近关系的同时搜索共生模式,导致在挖掘高阶共生模式时需要实时修正几何邻近关系,在复杂系统下丧失计算过程的灵活性。考虑到图数据蕴含的拓扑连接信息与空间同位模式相契合,本文提出一种基于图结构的空间同位模式挖掘方法。该方法一步完成几何上的邻近关系探测,然后在图数据库中通过子图搜索完成逻辑上的同位模式判别。首先,基于Delaunay三角网构建自适应邻接图,利用自适应邻接过滤器删除无效连接。然后,通过候选子图的不断连接、剪枝、生长,逐步从N元递推获取N+1元候选同位模式。最后,通过计算支持度指标并与预定义阈值比较以确定空间同位模式。本文基于不断生长迭代的图遍历思想提升了空间同位模式挖掘面向更复杂的空间场景的普适性。试验表明本文方法具备高效的挖掘能力,相较传统算法,在多元空间同位模式的挖掘任务中效果更优。

关键词：空间同位模式自适应邻接图图遍历 Apriori算法

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分布式新能源接入的10 kV配电网保护适应性分析

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电力建设 2024年第2期45卷 49-57页

作者：袁兆祥张翼聂铭李猛和敬涵国网经济技术研究院有限公司北京市102209 国家电网有限公司北京市100031 北京交通大学电气工程学院北京市100044

分布式电源(distributed generation,DG)的并网运行改变了传统单辐射式供电网络结构,同时潮流和负荷电流的双向流动影响了电力系统的安全稳定运行。针对分布式新能源接入10 kV配电网场景下的线路保护适应性进行分析,根据分布式电源接入... 详细信息

分布式电源(distributed generation,DG)的并网运行改变了传统单辐射式供电网络结构,同时潮流和负荷电流的双向流动影响了电力系统的安全稳定运行。针对分布式新能源接入10 kV配电网场景下的线路保护适应性进行分析,根据分布式电源接入位置不同,理论分析了新能源电源接入造成的助增电流、外汲电流、反向电流等对配电网现有保护的影响,明晰了分布式电源容量对保护性能的影响,量化了10 kV配电网保护性能边界条件,对于后续的保护配置方案以及保护新原理的研究提供理论支撑。仿真结果验证了保护适应性分析的正确性。

关键词：分布式电源(DG) 10 kV配电网保护适应性边界条件

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